Methylome profiling of cell-free DNA during the early life course in (un)complicated pregnancies using MeD-seq: Protocol for a cohort study embedded in the prospective Rotterdam pe... by Marjolein M van Vliet, Sam Schoenmakers, Ruben G Boers, Lotte E van der Meeren, Joost Gribnau, Régine P M Steegers-Theunissen

“…Maternal cell-free DNA (cfDNA) partly originates from the placenta and could enable the minimally invasive study of placental DNA methylation dynamics. …”
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A novel and efficient digital image steganography technique using least significant bit substitution by Shahid Rahman, Jamal uddin, Hameed Hussain, Sabir Shah, Abdu Salam, Farhan Amin, Isabel de la Torre Díez, Debora Libertad Ramírez Vargas, Julio César Martínez Espinosa

“…The LSB substitution method minimizes the error rate in the embedding process and is used to achieve greater reliability. …”
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Psychological impact and coping mechanisms among sudanese medical students: a study on anxiety, depression, behavioral, and cognitive changes post COVID-19 lockdown and ongoing con... by Ali Awadallah Saeed, Ahmad Mohammad Al Zamel, Abrar Abdu Abass, Aisha Ahmed Mohammed, Fidaaldeen Adil Abdallh, Hiba Elhadi Ali, Nooralain Mohammed Hassan, Raad Mohammed Osman, Toga Abdelmutaal Mohammed, Azza Osman Yousif, Lamya Bashir Eisa

“…Results Data analysis using SPSS 27 indicated minimal missing data (0.25%) among the 393 participants. …”
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Screening approaches and potential of isolated lactic acid bacteria for improving fermentation of Saccharina latissima by Evangelia Zioga, Susan Løvstad Holdt, Fredrik Gröndahl, Claus Heiner Bang-Berthelsen

“…Results By employing high-throughput analytical workflows, the screening processing time is minimized, and among the different strains from a well-characterized strain collection, it was possible to distinguish between strong acidifiers and to replicate similar results when the volumes were scaled from 96-well plates to lab-scale fermentations (40 mL) of whole seaweed. …”
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Problems and prospects of grapevine genetic resources preservation at “Magarach” Institute by A. A. Polulyakh, V. A. Volynkin, V. V. Likhovsko

“…To supplement the traditional method of grapevine genetic resources conservation in the field collection, we have developed a method of preserving the gene pool collection in vitro under the minimal growth conditions. At the institute “Magarach” we have formed a vegetative collection of 40 grapevine varieties, hybrids and clones in vitro, and this work is under way. …”
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Immunolipid magnetic bead-based circulating tumor cell sorting: a novel approach for pathological staging of colorectal cancer by Qingyan Deng, Weidong Li, Yueming Huang, Haitao Wang, Xinhao Zhou, Zhifen Guan, Bohao Cheng, Yao Wang

“…This system partially solves the problem of difficult tumor tissue sample collection and provides a reference for gene mutation testing in early diagnosis, therapeutic efficacy evaluation, prognosis assessment, and minimal metastasis detection in CRC patients, showing significant potential for clinical application, especially in targeted therapy gene testing for CRC.…”
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Cytotoxic and Apoptosis-Inducing Activity of Plants from the Family Asparagaceae in Relation to Human Alveolar Adenocarcinoma Cells by Y.N. Kamalova, V.V. Shtyreva, Essam Abdul-Hafeez, Omer H.M. Ibrahim, P.V. Zelenikhin, N.S. Karamova, O.N. Ilinskaya

“…Thus, it is urgent for scientists to search for alternative drugs with selective antitumor action and minimal side effects. It is known that some plant metabolites exhibit antioxidant, cytotoxic, and antitumor activity, while at the same time being less toxic than modern allopathic drugs. …”
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Efficacy and safety of anticoagulants on venous thromboembolism: a systematic review and network meta-analysis of randomized controlled trials by Weijie Fu, Maolin Zhao, Sheng Ding, Mei Xin, Ke Yang, Li Jiang, Fan Wu, Xiaochen Wu, Jian Wang, Jie Chen, Feng Gao, Siyi He

“…Additionally, after an exhaustive analysis of NOACs, analysis showed that apixaban (RR 0.5, 95%CI 0.17–1.46) had a superior performance in major bleeding compared to rivaroxaban (RR 3.87, 95%CI 1.48–10.09).ConclusionTIs and NOACs were superior in efficacy with minimal side effects, making them pivotal choices for both prevention and treatment of VTE. …”
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The fate and mobility of chromium, arsenic and zinc in municipal sewage sludge during the co-pyrolysis process with organic and inorganic chlorides by Mahboub Saffari, Masomeh Moazallahi, Rezvan Mashayekhi

“…While FeCl3 demonstrated better performance in Cr stabilization, these findings highlight the importance of selecting appropriate chlorinated additives based on the target heavy metal for optimizing biochar production and minimizing environmental impacts effectively.…”
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A CASE REPORT: A SCROTAL FLAP FOR PENILE PARAFFINOMA RECONSTRUCTION by Rr. Theodora Ratih Labdagati Iswara, Muhammad Aulia Ul Hakim, Jahnavi Malineni, Katrina Ysabelle Hidalgo

“… • The V-Y plasty can be used not only to form the penile shaft but also to minimize penile shortening. Abstract: Introduction: A large penile size is a source of pride and a symbol of masculinity for many men. …”
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Cold Ceramic in Endodontics Treatments: A Review by Amin Roshani, Seyyed Amirali Hashemi Baraz, Iman Shiezadeh

“…Clinical outcomes were generally favorable, with high success rates and minimal complications reported. Conclusion: All cases demonstrated radiographic and clinical healing and an absence of postoperative pain or infection during follow-up periods ranging from 3 months to 4 years. cold ceramics provide promising success rates and negligible complications in various clinical endodontic scenarios. …”
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The effect of combined thermal and sonication treatment on shelf life extension and quality retention of banana by Mahfujul Alam, Mir Meahadi Hasan, Mohammad Mainuddin Molla, Mrinal Kanti Debnath, Md Shakir Moazzem, Biddut Chandra Dey

“…Based on the findings, combined hot water and ultrasound treatment (HW+US) can be considered promising postharvest treatment of bananas, could extend their shelf life, minimize microbial contamination, and enhance overall quality retention during ambient storage. …”
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Low SAR compact wideband/dual-band semicircular slot antenna structures for sub-6 GHz 5G wireless applications by Reham W. Abd-Elsalam, Hussein E. Seleem, Mostafa M. Abd-Elnaby, Amr H. Hussein

“…A transmission line feed is included in the designed U-shaped radiating patch. To minimize the antenna size and control the bandwidth, a semicircle-defected ground structure is etched beneath the radiating patch. …”
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Physicochemical Characterization, Storage Stability Behavior, and Intestinal Bioaccessibility of Clove Extract Encapsulated Using Varying Combinations of Gum Arabic and Maltodextri... by Farhad Ahmadi, Hafiz A. R. Suleria, Frank R. Dunshea

“…Encapsulation was effective in protecting bioactive components of clove extract during storage at room (up to 40 days) or high temperature (60 °C for 7 days) and minimized the loss of antioxidant activity during storage, as compared to the clove extract in a non-encapsulated form. …”
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A Systematic Review and Meta-Analysis of Outcomes for Type 1 Diabetes after Bariatric Surgery by Alexandra Chow, Noah J. Switzer, Jerry Dang, Xinzhe Shi, Christopher de Gara, Daniel W. Birch, Richdeep S. Gill, Shahzeer Karmali

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Deguelin inhibits the proliferation of human multiple myeloma cells by inducing apoptosis and G2/M cell cycle arrest: Involvement of Akt and p38 MAPK signalling pathway by Sun Kening, Chen Ping, Zhang Liang, Lu Zhidong, Jin Qunhua

“…Deguelin specifically inhibited the multiple myeloma cell growth while the normal plasma cells were minimally affected. Multiple myeloma cells when treated with deguelin exhibited remarkably lower viability and colony-forming ability. …”
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Effect of jet flow control in front of the leading bogie on the aerodynamic drag and underbody slipstream of high-speed trains by Sha Huang, Zhi-Wei Li, Wen-Jing Peng, Jin-Rong Lin, Zun-Di Huang, Guang-Zhi Zeng

“…The impact of jet angle is comparatively less pronounced than that of jet velocity, the disparity in drag reduction rates caused by varying jet angles remains within a range of 2.4% at a specific jet velocity, and the mean slipstreams and turbulent variables demonstrate minimal changes with varying jet angles. Optimal aerodynamic drag reduction is achieved with an air jet velocity of 0.8U and an angle of 15°, which is 6.43% for the whole train. …”
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Factors Associated with Visit-to-Visit Variability of Blood Pressure Measured as Part of Routine Clinical Care among Patients Attending Cardiology Outpatient Department of a Tertia... by Thirunavukarasu Kumanan, Vathulan Sujanitha, Mahesan Guruparan, Nadarajah Rajeshkannan

“…In conclusion, we recommend simple practical measures to achieve sustainable BP control among hypertensive patients with DM and CKD to minimize the VVV and improve their cardiovascular outcome.…”
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Research on blow-out of shield tunnel in sandy soil with shallow burial by Yong-Xiang Shi, Yong-Xiang Shi, Bao-Ping Xi, Qi-Guang Di, Feng-Nian Wang, Feng-Nian Wang

“…The research on the failure zone found that an increase in the friction angle causes an enlargement of the failure zone and an increase in the dissipated power at the boundary, resulting in an exponential growth of the limit support pressure. The cohesion has a minimal effect on the shape and area of the failure zone, primarily manifesting as an increase in the dissipated power at the failure zone boundary. …”
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Learning curve and complications of unilateral biportal endoscopy–unilateral laminectomy bilateral decompression for lumbar spinal stenosis by Jiashen Shao, Zihan Fan, Hai Meng, Qi Fei

“…Conclusions: UBE is an effective minimally-invasive spinal endoscopic technique for treating lumbar spinal stenosis, offering short time to achieving surgical mastery and a low complication rate.…”
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