Progress in Treatment of Temporomandibular Joint Disorder by Wei YANG, Minghua XIE, Yu CAI, Zhuoming CHEN

“…., the curative effect is remarkable; He-Ne laser therapy could activate the intracranial morphine peptide system, inhibit the release of pain causing substances; when the conservative treatment is ineffective, minimally invasive surgery under the arthroscope can be selected to release adhesion and improve spasm. …”
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A Comparative Study of 0.25% Levobupivacaine, 0.25% Ropivacaine, and 0.25% Bupivacaine in Paediatric Single Shot Caudal Block by Jagdeep Sharma, Ruchi Gupta, Anita Kumari, Lakshmi Mahajan, Jasveer Singh

“…We conclude that levobupivacaine and ropivacaine provide similar intraoperative quality with minimal haemodynamic variability and shorter duration of postoperative analgesia without any significant complications when compared with racemic bupivacaine. …”
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Combined Use of Excimer Laser and High-Speed Rotational Atherectomy to Overcome a Severely Calcified Lesion in Endovascular Therapy by Keisuke Nakabayashi, Shinya Hata, Nobuhito Kaneko, Akihiro Matsui, Kazuhiko Tanaka, Hiroshi Ando, Minoru Shimizu

“…However, no devices (minimal balloon, microcatheter, or Crosser system) were able to pass the lesion in antegrade or retrograde manner, even though the child catheter support or needle cracking technique from outside/inside was applied. …”
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The Effect of Bariatric Surgery Volume on General Surgery Outcomes for Morbidly Obese Patients by Katheryn Hope Wilkinson, Ruizhe Wu, Aniko Szabo, Rana Higgins, Jon Gould, Tammy Kindel

“…HVBH may have a volume-outcomes relationship where the hospital and staff familiarity with the management principles required to minimize the postoperative risk associated with morbid obesity and improve patient outcomes.…”
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Effect of Low-Temperature Storage on Chemical Composition and Antimicrobial Activity of Honey by Dmitry V. Gruznov, Olga A. Gruznova, Alexey B. Sokhlikov, Anton V. Lobanov

“…At 0–5°C, the changes were minimal: hydrogen peroxide (H2O2) remained stable, and its concentration decreased by ≤ 12.2% after 12 months of storage. …”
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Continuous Improvements and Future Challenges of Air Pollution Control at an Advanced Semiconductor Fab by Hsueh-Hsing Lu, Ming-Chun Lu, Thi-Cuc Le, Zhiping An, David Y. H. Pui, Chuen-Jinn Tsai

“…Finally, the by-product NOx can be minimized by using low-NOx burners or de-NOx control technologies in the future.…”
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Identifying focus zones for the conservation and promotion of priority birds in Swiss farmland by Noëlle Klein, Antoine Adde, Adrienne Grêt‐Regamey, Antoine Guisan, Felix Herzog, Philippe Jeanneret, Sonja Kay

“…Multivariate clustering was used to identify zones that should be preserved (low management impact, high bird potential) and zones where conservation measures could be promoted (high management impact, high bird potential). Zones which were minimally impacted by management and had a high potential for birds included grassland with structures, covering ca. 18% of the studied farmland. …”
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Clinical profiling of psoriatic arthritis: an observational cross-sectional study from Karnataka Psoriatic Arthritis Cohort by Chanakya Kodishala, Vineeta Shobha, S Chandrashekara, Sharath Kumar, Vikram Haridas, Vijay K R Rao, Ramesh Jois, Manisha Daware, Yogesh Preet Singh, Shweta Singhai, B G Dharmanand, Pramod Chebbi, R Subramanian, Ashwini Kamath, Uma Karjiigi, Vikram Raj K Jain, Chethana Dharmapalaiah, Shiva Prasad, C Srinivasa, Ramya Janardana, Benzeeta Pinto, Beenish Nazir, A S Harshini, K M Mahendranath

“…Conclusions: We report high articular disease activity in half while cutaneous disease activity was minimal in majority.…”
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Nutrient conditions affect antimicrobial pharmacodynamics in Pseudomonas aeruginosa by Maik Kok, Thomas Hankemeier, J. G. Coen van Hasselt

“…We show that single-nutrient modifications minimally affected bacterial growth rate. For specific nutrient-antibiotic combinations, we find relevant alterations in antibiotic sensitivity (i.e., EC50) and the maximum drug effect (Emax), in particular for ciprofloxacin, colistin, imipenem, and tobramycin. …”
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Multi-stage structure-based virtual screening approach combining 3D pharmacophore, docking and molecular dynamic simulation towards the identification of potential selective PARP-1... by Mahmoud A. El Hassab, Wagdy M. Eldehna, Ghaneya S. Hassan, Sahar M. Abou-Seri

“…In an attempt to provide a future guide for developing selective inhibitors for PARP-1 over PARP-2 to minimize the resulting side effects from PARP-2 inhibitors, we constructed a structure-based virtual screening approach (SBVS). …”
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Oncolytic vaccinia virus armed with anti-CD47 nanobody elicit potent antitumor effects on multiple tumor models via enhancing innate and adoptive immunity by Jie Chen, Liu Yang, Mengyuan Li, Qian Ye, Shibing Wang, Zengpeng Li, Wenbin Qian

“…However, this therapeutic approach is often hampered by on-target side effects, physical barriers, and immunosuppressive tumor microenvironment (TME).Methods To improve therapeutic efficacy while minimizing toxicities, we engineered an oncolytic vaccinia virus (OVV) encoding an anti-CD47 nanobody (OVV-αCD47nb). …”
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Fieldwork on animals living in extreme conditions as a source of biomedical innovation by Yvon Le Maho, Aurélie Tasiemski, Fabrice Bertile, Philippe Bulet

“…Specific techniques and methods are requested, not only to work in extreme environments, but also to minimize the ecological footprint of field work. The erosion of biodiversity is a major threat. …”
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Issues of diagnostics and treatment of abdominal pain at irritable bowel syndrome at outpatient stage of the healthcare by Yu. A. Kucheryavy, T. L. Lapina, M. A. Livzan, M. F. Osipenko

“…In the case of visceral pain the minimal range of laboratory and instrumental tests is indicated. …”
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Establishment of an oral burn model in streptozotocin-induced diabetic rats by Su-Young Kim, Seong-Gon Kim, Dae-Won Kim, Ji-Hyeon Oh

“…In contrast, Groups P5 and P3 showed minimal healing. This faster healing on the tongue was further supported by significantly lower expression levels of TNF-α and IL-1β and a reduction in ulcer size, particularly on the tongue compared to the palate. …”
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Efficacy and safety of anti-CD38 monoclonal antibodies-based therapy versus standard therapy in newly diagnosed multiple myeloma patients: a systematic review and meta-analysis by Muhammad Osama, Muhammad Haris Khan, Safeena Khan, Amna Hussain, Ammara Tahir, Mehran Ullah, Abdullah Afridi, Ubaid Ullah, Wajeeh Ur Rehman

“…The primary outcomes were progression-free survival (PFS) and minimal residual disease (MRD) status. Dichotomous outcomes were pooled using risk ratio (RR) along with the 95% confidence interval (CI) in RevMan 5.4. …”
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Urinary Calculi: A Microbiological and Biochemical Analysis at a Tertiary Care Hospital in Eastern Nepal by Pratima Shah, Ratna Baral, C. S. Agrawal, Madhab Lamsal, Dharanidhar Baral, Basudha Khanal

“…This study emphasizes the use of appropriate antimicrobial agents to prevent the regrowth of residual stones and minimize the risk of infectious complications after surgical removal of stones.…”
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Aplicación del modelo "Antecedente-Comportamiento-Consecuencia" en la construcción de lumbreras y túneles Application of an "Antecedent-Behavior-Consequence" model... by Victor Jiménez Arguelles, Jesús A Bustamante, Luis A Rocha Chiu

“…Considering that the construction of the project will require three more years, the second part of the research aims to develop and implement a plan of labor risks prevention (LRP) based on the behavioral intervention of workers, in order to minimize the presence of accidents at work.…”
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A Panel of Three MicroRNA Signatures as a Potential Biomarker for CRC Screening Based on Stages and Functional Prediction Using Bioinformatic Analysis by Syarah Syamimi Mohamed, Azmir Ahmad, Nurul Syakima Ab Mutalib, Tengku Ahmad Damitri Al-Astani Tengku Din, Md Salzihan Md Salleh, Andee Dzulkarnaen Zakaria, Zaidi Zakaria

“…The reflective circulating miRNAs can be contributed to by minimal invasive screening tools. …”
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Enhanced ensemble learning-based uncertainty and sensitivity analysis of ventilation rate in a novel radiative cooling building by Majid Mohsenpour, Mohsen Salimi, Atieh Kermani, Majid Amidpour

“…The analysis reveals that uncertainties have minimal impact in the reference building, while the test building demonstrates greater sensitivity during warmer months, emphasizing the importance of accounting for seasonal variations. …”
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Participatory research towards the control of snakebite envenoming and other illnesses in a riverine community of the Western Brazilian Amazon. by Alícia Patrine Cacau Santos, Evellyn Antonieta Rondon Tomé Silva, Hiran Sátiro Souza da Gama, Jady Shayenne Mota Cordeiro, Ana Paula Silva Oliveira, Jéssica Albuquerque Araújo, Rafaela Nunes Dávila, Hélio Afonso Amazonas Júnior, Altair Seabra Farias, Jacqueline Almeida Gonçalves Sachett, Vinícius Azevedo Machado, Wuelton Marcelo Monteiro, Felipe Leão Gomes Murta

“…In this scenario, the significant burden of snakebite envenoming (SBE) highlights the need for participatory research to address ways to minimize this situation. Thus, this study aimed to describe the priority health problems identified by this population and the ranking of SBEs in that context, mapping solutions according to the local reality.…”
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