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8501
Tanshinlactone triggers methuosis in breast cancer cells via NRF2 activation
Published 2025-01-01“…This regimen holds promise for targeted therapy with minimized side effects and offers a new therapeutic avenue for breast patients with drug-resistant diseases.…”
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8502
Stress, Anxiety and Depression in First-year Medical Undergraduates and Coping Strategies Employed during COVID-19-induced Online Learning: A Cross-sectional Study from North India
Published 2024-12-01“…Their physical classes were suspended due to the onset of second wave of COVID-19 and underwent a significant shift from conventional classes to a hybrid teaching module involving online classes, minimal face-to-face contact with teachers and almost no practical exposure which is in contrast to the conventional teaching practices. …”
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8503
The winding road to health: A systematic scoping review on the effect of geographical accessibility to health care on infectious diseases in low- and middle-income countries.
Published 2021-01-01“…Results of the included publications could be broadly categorized into three groups: (1) decreased spatial accessibility to health care was associated with a higher infectious disease burden, (2) decreased accessibility was associated to lower disease reporting, minimizing true understanding of disease distribution, and (3) the occurrence of an infectious disease outbreak negatively impacted health care accessibility in affected regions. …”
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8504
Reproducibility of peak force for isometric and isokinetic multi-joint leg extension exercise
Published 2025-01-01“…Bland-Altman plots depicted minimal intersession disparities (-141.8–68.3 N, respectively − 3.02–1.26%), supporting high reliability. …”
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8505
Microstructural analysis and preliminary wear assessment of wire arc additive manufactured AA 5083 aluminum alloy for lightweight structures
Published 2025-01-01“…Hardness levels are consistent in the X-direction and show minimal variance in the Y-direction, with an average hardness of 89.4 ± 5.14 HV0.5. …”
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8506
Impact of Renewable Energy Sources on the Electricity Generation Cost
Published 2023-12-01“…A fundamental model of the energy system of the Republic of Belarus was also built. The principle of minimizing total system costs is chosen as the objective function for modeling, provided that a number of restrictions imposed on the power system are met. …”
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8507
'once they see blood then the mood for sex is spoiled' A qualitative exploration of female sex worker's male client views of menstruation, sex during menses and the menstrual disc.
Published 2024-01-01“…These findings suggest potential for adoption of menstrual discs by FSW with minimal adverse client reaction, and highlight possible partner support for women considering adopting a menstrual disc.…”
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8508
Comparison of the Migration Potential through Microperforated Membranes of CD146+ GMSC Population versus Heterogeneous GMSC Population
Published 2021-01-01“…GMSCs fulfilled all the minimal criteria of stem cells and showed low signal 10% for CD146 on average and extremely low signal 2% for CD271 on average. …”
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8509
Molecular Dynamics Insights into Peptide-Based Tetrodotoxin Delivery Nanostructures
Published 2024-12-01“…Tetrodotoxin (TTX), a potent Site-1 sodium channel blocker (S1SCB), offers highly effective local anesthetic properties with minimal addiction potential. To fully leverage TTX’s capabilities as a local anesthetic, it is crucial to develop a drug delivery system that balances its systemic toxicity with its therapeutic efficacy. …”
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8510
Attitudes towards transjugular intrahepatic portosystemic shunt (TIPS) in Australia: a national survey of TIPS centres
Published 2024-06-01“…Background Transjugular intrahepatic portosystemic shunt (TIPS) is a minimally invasive therapeutic option to treat the sequelae of portal hypertension. …”
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8511
A 250 °C Low-Power, Low-Temperature-Drift Offset Chopper-Stabilized Operational Amplifier with an SC Notch Filter for High-Temperature Applications
Published 2025-01-01“…The two-stage operational amplifier uses both cascode and Miller compensation, minimizing the influence of the feedforward signal path and improving the amplifier’s response speed. …”
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8512
Estimating whole-body centre of mass sway during quiet standing with inertial measurement units.
Published 2025-01-01“…We then calculated the correlation between the IMU- and force platform- CoM estimates to determine the minimal number of IMUs needed to estimate CoM sway. …”
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8513
STAT3 Expression and Its Correlation with PD-L1 Expression in Non-Hodgkin’s Lymphoma and Hodgkin’s Lymphoma at Dr. Saiful Anwar Regional Public Hospital in Malang, Indonesian Popul...
Published 2024-01-01“…Despite the availability of many therapeutic modalities for lymphoma, such as Brentuximab vedotin, Nivolumab, and Pembrolizumab, it is still necessary to identify appropriate strategies with minimal side effects. Immunotherapy is a promising approach, exemplified by targeting JAK/STAT3 signaling, which can inhibit tumor growth and enhance antitumor immune responses. …”
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8514
Regional Elastic Properties of the Achilles Tendon Is Heterogeneously Influenced by Individual Muscle of the Gastrocnemius
Published 2019-01-01“…The intraoperator ICC of the gastrocnemius muscle-Achilles tendon complex was 0.77 to 0.95, while the interoperator ICC was 0.76 to 0.94. The minimal detectable change (MDC) of the muscle was 1.72 kPa, while the AT was 32.90 kPa. …”
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8515
Chlorpromazine and Promethazine (C+P) Reduce Brain Injury after Ischemic Stroke through the PKC-δ/NOX/MnSOD Pathway
Published 2022-01-01“…This study investigated how C+P minimizes oxidative stress triggered by ischemic injury. …”
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8516
Third Trimester Lower Extremity Lymphorrhea
Published 2021-01-01“…In this patient, the capillary hydrostatic pressure was likely accentuated due to hypertension, obesity, and vaping. Furosemide was minimally effective to alleviate her symptoms. Torsemide provided much more effective diuresis and symptom control. …”
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8517
Microscopic Mechanism Affecting Shear Strength in Lignin-Treated Loess Samples
Published 2019-01-01“…The use of lignin as a stabilizing additive for valley fill material shows potential for controlling building foundation deformation by increasing soil strength and minimizing environmental impacts by maintaining the soil pH and limiting pollutant production.…”
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8518
Level of Awareness, Screening Practices, and Self-Detection Among Breast Cancer Patients
Published 2025-01-01“…Having previous knowledge and doing pre-tests regularly play a key role in the early detection of this cancer, which minimizes the consequences.…”
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8519
Sex and Age Comparisons in Neuromuscular And Biomechanical Characteristics of the Knee in Young Athletes
Published 2021-04-01“…These differences may be minimized through appropriate age and sex specific training programs…”
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8520
Leasing business organization based on a digital platform
Published 2024-12-01“…The digital platform assumes minimal human participation in the process of forming a commercial proposal and agreement, ensures digitalization of the transaction process, reducing the time and human resources of the lessee and lessor to conclude a leasing agreement. …”
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