Integrative analysis of miRNA expression data reveals a minimal signature for tumour cells classification by Sabrina Napoletano, David Dannhauser, Paolo Antonio Netti, Filippo Causa

“…Our results demonstrate a highly significant differentiation of cancer types, achieving 100 % classification accuracy with minimal training time using a streamlined miRNA signature. …”
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Minimally important change on the Columbia Impairment Scale and Strengths and Difficulties Questionnaire in youths seeking mental healthcare by Peter Szatmari, Claire de Oliveira, Myla E Moretti, Kristin Cleverley, Lisa D Hawke, Amy H Cheung, Meaghen Quinlan-Davidson, Clement Ma, Karolin R Krause, Alina Lee, Di Shan, Katherine Tombeau Cost, Jo L Henderson

“…Background Evidence-based mental health requires patient-relevant outcome data, but many indicators lack clinical meaning and fail to consider youth perceptions. The minimally important change (MIC) indicator designates change as meaningful to patients, yet is rarely reported in youth mental health trials.Objective This study aimed to establish MIC thresholds for two patient-reported outcome measures (PROMs), the Columbia Impairment Scale (CIS) and the Strengths and Difficulties Questionnaire (SDQ), using different estimation methods.Methods A sample of 247 youths (14–17 years) completed the CIS and SDQ at baseline and at 6 months in a youth mental health and substance use trial. …”
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Utilization of Waste Textile Cotton by Synthesizing Sodium Carboxymethyl Cellulose: An Approach to Minimize Textile Solid Waste by Md. Samsur Rahaman, Sultana Shamsun Nahar, Jahid M. M. Islam, Rajib Samadder, Md. Saifur Rahaman, Rujina Khatun Chadni, Faisal Rahaman Shagor, Md. Latifur Rahman, Tania Akter Ruhane, Mubarak Ahmad Khan

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Minimal Impacts of Tyre Particle Exposure on Estuarine Meiofaunal Community Structure, Primary Production, and Nutrient Cycling by Charlotte Woodhouse, Dannielle Senga Green, Andy Foggo, Paul J. Somerfield, Richard C. Thompson, Samantha L. Garrard

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Maintenance Scheduling of Wind Units from the Power Plant Owner’s Perspective with the Objective of Minimizing Economic Loss by Amir Allame, Asghar Akbari Foroud

“…The maintenance scheduling of wind units can be analyzed through the lens of an Independent System Operator (ISO) with goals that encompass cost minimization, enhanced system reliability, or improved social welfare. …”
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Cost-Minimization Analysis for Subcutaneous Daratumumab in the Treatment of Newly Diagnosed Multiple Myeloma in Three Gulf Countries by Anas Hamad, Shereen Elazzazy, Ruba Y. Taha, Hani Osman, Sana Alblooshi, Islam Elkonaissi, Mustaqeem A. Siddiqui, Khalil Al-Farsi, Mohammed Al Lamki, Sali Emara, Gihan H. Elsisi

“…**Objective:** To assess the financial effects of the adoption of subcutaneous daratumumab (dara-SC) rather than intravenous daratumumab (dara-IV) for the treatment of NDMM in three Gulf countries (Qatar, Oman and the United Arab Emirates; UAE), a cost-minimization model was constructed. **Methods:** We performed static cost minimization analyses from a societal perspective to evaluate the costs and possible reductions in resource utilization associated with a shift from dara-IV infusion to dara-SC injection for NDMM patients over a 5-year time horizon. …”
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Analysis of the Density of Electron-Hole Pairs for Minimal Pump Energy in a Laser Diode with Coherent Feedback by M. A. Grado-Caffaro, M. Grado-Caffaro

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Increasing the self-sufficiency of a university campus by expanding the PV capacity while minimizing the energy cost by Randrianantenaina Tina Arizo, Le Gal La Salle Josselin, Spataru Sergiu Viorel, David Mathieu

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Experimental Studies of Fluid Flow Resistance in a Heat Exchanger Based on the Triply Periodic Minimal Surface by Marcin Kruzel, Krzysztof Dutkowski, Tadeusz Bohdal

“…The device’s design is based on the triply periodic minimal surface (TPMS) geometry called gyroid, which can only be obtained by incremental manufacturing. …”
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Hybrid Gradient-Projection Algorithm for Solving Constrained Convex Minimization Problems with Generalized Mixed Equilibrium Problems by Lu-Chuan Ceng, Ching-Feng Wen

“…It is well known that the gradient-projection algorithm (GPA) for solving constrained convex minimization problems has been proven to have only weak convergence unless the underlying Hilbert space is finite dimensional. …”
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Algorithm for Solutions of Nonlinear Equations of Strongly Monotone Type and Applications to Convex Minimization and Variational Inequality Problems by Mathew O. Aibinu, Surendra C. Thakur, Sibusiso Moyo

“…Nonlinear equations occur in modeling problems, such as minimizing costs in industries and minimizing risks in businesses. …”
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A Cutting Plane and Level Stabilization Bundle Method with Inexact Data for Minimizing Nonsmooth Nonconvex Functions by Jie Shen, Dan Li, Li-Ping Pang

“…Under the condition that the values of the objective function and its subgradient are computed approximately, we introduce a cutting plane and level bundle method for minimizing nonsmooth nonconvex functions by combining cutting plane method with the ideas of proximity control and level constraint. …”
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Minimally Invasive Approach for Improving Anterior Dental Aesthetics: Case Report with 1-Year Follow-Up by H. Sevilay Bahadır, Gökhan Karadağ, Yusuf Bayraktar

“…Treating aesthetic demands with noninvasive or minimally invasive techniques can preserve the natural tissues. …”
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Spinal Metastasis of Well-Differentiated Liposarcoma Component in Retroperitoneal Dedifferentiated Liposarcoma Treated by Minimally Invasive Surgery by Jiro Ichikawa, Tetsuro Ohba, Hiroaki Kanda, Koji Fujita, Shigeto Ebata, Hirotaka Haro

“…We should carefully consider characteristics of DDLs during treatment. Minimally invasive surgery may be a powerful tool in patients with spinal metastasis.…”
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Iterative Approximation of the Minimal and Maximal Positive Solutions for Multipoint Fractional Boundary Value Problem on an Unbounded Domain by Guotao Wang, Sanyang Liu, Lihong Zhang

“…By employing the monotone iterative method, this paper not only establishes the existence of the minimal and maximal positive solutions for multipoint fractional boundary value problem on an unbounded domain, but also develops two computable explicit monotone iterative sequences for approximating the two positive solutions. …”
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Fracture Healing with Minimal Post Fracture Stiffness through Jingini Taila Bandage: A Case Study by Sreenadh P., T.S. Dudhamal

“…This study aims to facilitate proper fracture healing while minimizing post-cast stiffness by adhering to traditional Ayurvedic principles of fracture management. …”
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Optimization design based approach for the determination and minimization of the displacement under tensile load in hybrid composite joint by Fouzia Merabbi, Abdelkader Lousdad, Abdelkader Megueni, Abderahmane Sahli

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Minimizing skull defects in retrosigmoid approach: precision mapping of the sigmoid sinus with mastoid emissary vein canal by Artem V. Rozumenko, Mykola V. Yehorov, Vasyl V. Shust, Dmytro M. Tsiurupa, Anton M. Dubrovka, Petro M. Onishchenko, Volodymyr O. Fedirko

“…By facilitating precise sigmoid sinus mapping, the technique reduces the extent of bone removal and minimizes postoperative cranial defect.…”
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NGS Analysis of Clonality and Minimal Residual Disease in a Patient with Concurrent Richter’s Transformation and CLL/SLL by Shrihari S. Kadkol, Joshua Bland, Ashley Kavanaugh, Hongyu Ni, Vijeyaluxmi Nehru, David Peace

“…We show that NGS analysis facilitated clinical management in our patient by helping to characterize the VDJ rearrangement in detail and by tracking minimal residual disease with high sensitivity and specificity.…”
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Understanding and Minimizing Perimeter Losses of Silicon-Based Monolithic Tandem Solar Cells – A Simulation Study by Andreas Fell, Martin Bivour, Mario Hanser, Martin Schubert

“…An understanding of perimeter loss mechanisms and design rules for their minimization is therefore important for effectively progressing high efficient tandem solar cells in R&D. …”
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