LBP-CD155 Liposome Nanovaccine Efficiently Resist Colorectal Cancer and Enhance ICB Therapy by Yan Y, Duan T, Xue X, Yang X, Liu M, Ma B, Duan X, Su C

“…The nanovaccine was characterized by transmission electron microscopy and Zetasizer. It was evaluated in vitro, where NVs facilitated the endocytosis and maturation of DCs, and in vivo, where NVs improved the efficacy of prophylaxis and therapy. …”
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Xpert Ultra stool testing to diagnose tuberculosis in children in Ethiopia and Indonesia: a model-based cost-effectiveness analysis by Peter J Dodd, Nyashadzaishe Mafirakureva, Rina Triasih, Debebe Shaweno, Jens Levy, Eveline Klinkenberg, Petra de Haas, Ineke Spruijt, Nastiti Kaswandani, Ahmed Bedru, Melaku Gebremichael, Edine W Tiemersma

“…Costs increased under the intervention compared with a base case using smear microscopy in the standard of care resulting in incremental cost-effectiveness ratios of US$132 and US$94 per DALY averted in Ethiopia and Indonesia, respectively. …”
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Geological characteristics of deep coal rock and main geological factors controlling coalbed methane enrichment: a case study of the M area in the eastern Ordos Basin by Xiaojiao GUO, Lei WANG, Xianzhou YAO, Xu LI, Linke ZHANG, Xiaoshuang WANG

“…To promote increased reserves and efficient production of deep CBM, and to further develop the enrichment theory of deep CBM in the eastern Ordos Basin, a comprehensive study was conducted based on core observations, experimental tests, scanning electron microscopy, well logging data from 76 wells in the study area, and 3D seismic data. …”
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Suppressing GDF15 enhances the chemotherapeutic effect of 5 FU on MSI-H CRC by regulating the ferroptosis pathway SLC7A11/GSH/GPX4 by Zhi min Huang Fu, Ming Xiao, Hailun Xie, Shuxian Zhang, Tang Yi, Qingshu Li, Ming Li, Yalan Wang

“…We examined alterations in mitochondria via electron microscopy and changes in the mitochondrial membrane potential, ferroptosis-related signals (MDA, Fe2+), and SLC7A11/GSH/GPX4 protein pathway. …”
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Screening of N-Acyl Homoserine Lactone-degrading Bacteria and Evaluation of Their Quorum Quenching Activities by Xiqian TAN, Xiaoqing WANG, Fangchao CUI, Dangfeng WANG, Xinran LÜ, Xuepeng LI, Jianrong LI

“…The crystal violet staining and optical microscopy assay indicated that the isolated strains exhibited different inhibitory and dispersion capabilities against the biofilm of H. alvei. …”
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Pore Structure and Its Fractal Dimension: A Case Study of the Marine Shales of the Niutitang Formation in Northwest Hunan, South China by Wei Jiang, Yang Zhang, Tianran Ma, Song Chen, Yang Hu, Qiang Wei, Dingxiang Zhuang

“…To analyze the pore structure and fractal characteristics of marine shale in the lower Cambrian Niutitang Formation in northwestern Hunan Province, China, the pore characteristics of shale were characterized using total organic carbon (TOC) content, field emission scanning electron microscopy (FESEM), X-ray diffraction (XRD), low temperature nitrogen adsorption (LT-N₂GA) and methane adsorption experiments. …”
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Evaluation of the protective role of resveratrol on LPS-induced septic intestinal barrier function via TLR4/MyD88/NF-κB signaling pathways by Zhongliang Shi, Yanna Jiao, Zhizhen Lai, Juan Liu, Bo Yang, Mahong Hu, Jianbiao Meng

“…Various techniques including enzyme-linked immunosorbent assay (ELISA), hematoxylin and eosin staining (HE), periodic acid Schiff (PAS) staining, transmission electron microscopy (TEM), Western blot analysis (WB), and quantitative real-time polymerase chain reaction (qRT-PCR) were utilized to assess differences in inflammatory cytokine expression, histopathological changes, apoptosis, tight junction (TJ) protein, and the TLR4/MyD88/NF-кB signaling pathways. …”
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Itraconazole promotes melanoma cells apoptosis via inhibiting hedgehog signaling pathway-mediated autophagy by Shunqiao Jin, Shunqiao Jin, Xiaojiao Liu, Xiaojiao Liu, Lingqin Cai, Lingqin Cai, Jiayu Yan, Ling Li, Hongjun Dong, Yuxue Gao, Xicong Zhu, Cong Zhang, Xuezhu Xu

“…Western blot analysis was performed to examine autophagy and associated signaling proteins, while autophagy flux and autophagosome formation were visualized using fluorescence microscopy. A melanoma cell xenograft mouse model was established to evaluate the inhibitory mechanisms of itraconazole on tumor cell proliferation.ResultUsing the PMF machine learning algorithm, SQSTM1 was identified as the primary target of itraconazole. …”
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Hirudo extract ameliorates proliferative vitreoretinopathy by promoting autophagy and attenuating the THBS2/PI3K/Akt pathway by Hui Huang, Qun Huang, Jing Wang, Wanjie Wang, Yanlin Zheng

“…Autophagy was observed via transmission electron microscopy. The mRNA expression of MMP9, N-cadherin, vimentin, THBS2, PI3K, and Akt was measured via RT‒qPCR. …”
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Gallic acid alleviates exercise-induced muscle damage by inhibiting mitochondrial oxidative stress and ferroptosis by Likai Yu, Di Tian, Zishan Su, Li Zhang, Shaobo Guo, Wenhui Zhu, Yuan Fang, Peimin Wang, Nongshan Zhang

“…Transmission electron microscopy was used to observe the morphology of mitochondria. …”
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Eco-Friendly Synthesis of Zirconium Dioxide Nanoparticles from <i>Toddalia asiatica</i>: Applications in Dye Degradation, Antioxidant and Antibacterial Activity by Arumugam Kathirvel, Ramalingam Srinivasan, Sathasivam Harini, Natarajan Ranjith, Govindan Suresh Kumar, Kesavan Lalithambigai, Raji Atchudan, Mohamed A. Habila, Ahmed M. Aljuwayid, Hae Keun Yun

“…Analytical techniques, including various spectroscopy methods and electron microscopy, confirmed the formation of aggregated spherical ZrO₂ NPs, ranging from 15 to 30 nm in size, with mixed-phase structure composed of tetragonal and monoclinic structures. …”
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Polydomus karssenii gen. nov. sp. nov. is a dark septate endophyte with a bifunctional lifestyle parasitising eggs of plant parasitic cyst nematodes (Heterodera spp.) by Samad Ashrafi, Jan-Peer Wennrich, Yvonne Becker, Jose G. Maciá-Vicente, Anke Brißke-Rode, Matthias Daub, Torsten Thünen, Abdelfattah A. Dababat, Maria R. Finckh, Marc Stadler, Wolfgang Maier

“…Confocal laser scanning microscopy further demonstrated that the fungus colonised the root cells by predominant intercellular growth of hyphae, and frequent formation of appressorium-like as well as penetration peg-like structures through internal cell walls surrounded by callosic papilla-like structures. …”
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Boanmycin overcomes bortezomib resistance by inducing DNA damage and endoplasmic reticulum functional impairment in multiple myeloma by Jin-Xing Wang, Ling Zhang, Peng-Wei Zhang, Luo-Wei Yuan, Jian Jiang, Xiao-Hui Cheng, Wei Zhu, Yong Lei, Fa-Qing Tian

“…Cellular morphology was observed via transmission electron microscopy. Colony formation ability was evaluated, and cell apoptosis and the cell cycle were detected through flow cytometry. …”
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WKB ameliorates DSS-induced colitis through inhibiting enteric glial cells activation and altering the intestinal microbiota by Qi Sun, Bai-Rong Li, Dong-Hao Li, Xiao-Ying Wang, Qian-Yi Wang, Zhi-Meng Jiang, Shou-Bin Ning, Tao Sun

“…Epithelial barrier integrity was evaluated using immunofluorescence, transmission electron microscopy, and permeability assays. EGCs activity was analyzed via immunofluorescence and quantitative real-time PCR. …”
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Ionizing radiation and photodynamic therapy lead to multimodal tumor cell death, synergistic cytotoxicity and immune cell invasion in human bladder cancer organoids by Annabell Reinhold, Annegret Glasow, Sandra Nürnberger, Annett Weimann, Lucie Telemann, Jens-Uwe Stolzenburg, Jochen Neuhaus, Mandy Berndt-Paetz

“…Cytotoxicity was determined by microscopy, cell-based assays and histology. The cell death mode was analyzed by applying specific inhibitors followed by immunofluorescence or qPCR analyses of cell death markers. …”
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Biaxial fatigue behavior of a powder metallurgical TRIP steel by S. Ackermann, T. Lippmann, D. Kulawinski, S. Henkel, H. Biermann

“…Different types of major cracks were observed on the sample surfaces after biaxial cyclic deformation by using electron monitoring in an electron beam universal system and scanning electron microscopy (SEM). Specimens with strain ratios of 1, 0.5, -0.1 and -0.5 showed mode I major cracks (perpendicular to the axis of maximum principal strain). …”
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Application of green silver nano-particles as anti-bacterial and photo-catalytic degradation of azo dye in wastewater by Zainab Haider Ali, Lubna Abdulazeem, Wurood Alwan Kadhim¹, Mazin H. Kzar³, Osamah J. Al-sareji

“…The synthesized AgNPs were subsequently subjected to characterization utilizing several analytical methods, namely UV-visible spectroscopy, scanning electron microscopy (SEM), X-ray diffraction, and Fourier transform infrared spectroscopy (FTIR analysis). …”
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Anthelmintic Activity of Crude Extract and Essential Oil of Tanacetum vulgare (Asteraceae) against Adult Worms of Schistosoma mansoni by Loyana Silva Godinho, Lara Soares Aleixo de Carvalho, Clarissa Campos Barbosa de Castro, Mirna Meana Dias, Priscila de Faria Pinto, Antônio Eduardo Miller Crotti, Pedro Luiz Silva Pinto, Josué de Moraes, Ademar A. Da Silva Filho

“…Confocal laser scanning microscopy showed morphological alterations in the tegument of the S. mansoni surface after incubation with TV (50 and 100 μg/mL). …”
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Pore Preservation and Failure Mechanism of Sinian Dengying Formation Carbonate Reservoirs: A Case Study of Two Ultradeep Wells in the Sichuan Basin, Western China by Zeqi Li, Wei Sun, Shugen Liu, Zhiwu Li, Bin Deng, Juan Wu, Yi Ding, Kun Jiao, Xin Jin, Pengda Lu, Tengzhen Tian

“…This study performed thin-section, geochemistry, field emission scanning electron microscopy, fluid inclusion, and basin model analysis of samples from two boreholes over 8,000 m deep in the Sichuan Basin to determine the pore features and preservation mechanism of the Sinian (Ediacaran) Dengying Formation carbonate reservoirs. …”
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Effects of acteoside from Cistanche tubulosa on the plasma metabolome of cancer-related fatigue mice inoculated with colon cancer cells by Shilei Zhang, Fukai Gong, Jiali Liu, Shuping You, Tao Liu, Jianhua Yang, Junping Hu

“…Fatigue-associated behaviors, tumor inhibition rate, and skeletal muscle morphology assessed by hematoxylin-eosin (H&amp;E) staining and electron microscopy were evaluated. Finally, liquid chromatography-mass spectrometry (LC/MS) was employed to investigate alterations in the plasma metabolic profile of tumor-bearing mice with CRF in response to ACT treatment, and the affinity between metabolite-associated proteins and ACT was verified by Surface plasmon resonance (SPR) assay.ResultsOur study demonstrated the presence of CRF in the colon cancer mouse model, with the severity of fatigue increasing alongside tumor growth. …”
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