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Time series segmentation for recognition of epileptiform patterns recorded via microelectrode arrays in vitro.
Published 2025-01-01“…The algorithms were validated validated against epileptiform activity induced by 4-aminopyridine in mouse hippocampus-cortex (CTX) slices and recorded via microelectrode array, as a case study. The ZdensityRODE algorithm showcased a precision and recall of 93% for ictal event detection and 42% precision for interictal event detection, while the AMPDE algorithm attained a precision of 96% and recall of 90% for ictal event detection and 54% precision for interictal event detection. …”
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Impedance mapping with high-density microelectrode array chips reveals dynamic heterogeneity of in vitro epithelial barriers
Published 2025-01-01Subjects: “…CMOS microelectrode arrays…”
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Simultaneous recording of neuronal discharge and calcium activity reveals claustrum-cortex neurosynchrony under anesthesia
Published 2025-01-01Subjects: “…Microelectrode array…”
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Microfabricated sensors for non-invasive, real-time monitoring of organoids
Published 2024-12-01Subjects: Get full text
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Multi-channel microelectrode arrays for detection of single-cell level neural information in the hippocampus CA1 under general anesthesia induced by low-dose isoflurane
Published 2025-01-01“…In this research, four-shank 32-channel implantable microelectrode arrays (MEAs) were developed for the real-time recording of single-cell level neural information in rat hippocampal CA1. …”
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Network-wide effects of pallidal deep brain stimulation normalised abnormal cerebellar cortical activity in the dystonic animal model
Published 2025-02-01Subjects: Get full text
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High-density multielectrode arrays bring cellular resolution to neuronal activity and network analyses of corticospinal motor neurons
Published 2025-01-01“…Here, we combine optical imaging with high-density microelectrode array (HD-MEA) system enabling single cell resolution and utilize UCHL1-eGFP mice to bring cell-type specificity to our understanding of the electrophysiological features of healthy CSMN, as they mature and form network connections with other cortical neurons, in vitro. …”
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Fluorescent identification of axons, dendrites and soma of neuronal retinal ganglion cells with a genetic marker as a tool for facilitating the study of neurodegeneration
Published 2025-01-01“…Controls indicated no impact of Slc17a6‐tdTomato expression on light‐dependent neuronal function as measured with a microelectrode array (MEA), or on retinal structure as measured with optical coherence tomography (OCT). …”
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NeuTox 2.0: A hybrid deep learning architecture for screening potential neurotoxicity of chemicals based on multimodal feature fusion
Published 2025-01-01“…Four datasets were used to profile neurotoxicity; these were related to blood–brain barrier permeability, neuronal cytotoxicity, microelectrode array–based neural activity, and mammalian neurotoxicity. …”
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Extracellular Recordings of Patterned Human Pluripotent Stem Cell-Derived Cardiomyocytes on Aligned Fibers
Published 2016-01-01“…To create tissue-like constructs of CMs for extracellular monitoring, we placed aligned fibers (AFs) on the surface of a microelectrode array and then seeded hiPSC-CMs for subsequent monitoring for 14 days. …”
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Electrical excitability of neuronal networks based on the voltage threshold of electrical stimulation
Published 2024-12-01“…Abstract Microelectrode arrays (MEAs) have been widely used in studies on the electrophysiological features of neuronal networks. …”
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Microelectrothermoforming (μETF): one-step versatile 3D shaping of flexible microelectronics for enhanced neural interfaces
Published 2025-01-01“…Abstract Increasing the proximity of microelectrode arrays (MEA) to targeted neural tissues can establish efficient neural interfaces for both recording and stimulation applications. …”
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Intelligent in-cell electrophysiology: Reconstructing intracellular action potentials using a physics-informed deep learning model trained on nanoelectrode array recordings
Published 2025-01-01“…We developed a physics-informed deep learning model to reconstruct iAP waveforms from extracellular recordings recorded from NEAs and Microelectrode arrays (MEAs), demonstrating its potential for non-invasive, long-term, high-throughput drug cardiotoxicity assessments. …”
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Botulinum Toxin Suppression of CNS Network Activity In Vitro
Published 2014-01-01“…Murine spinal cord and frontal cortex networks cultured on substrate integrated microelectrode arrays allowed monitoring of spontaneous spike and burst activity with exposure to BoNT serotype A (BoNT-A). …”
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