Using Aptamers for Cancer Biomarker Discovery by Yun Min Chang, Michael J. Donovan, Weihong Tan

“…Aptamers can be paired with recent advances in nanotechnology, microarray, microfluidics, and other technologies for applications in clinical medicine. …”
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The Influence of Adalimumab and Cyclosporine A on the Expression Profile of the Genes Related to TGFβ Signaling Pathways in Keratinocyte Cells Treated with Lipopolysaccharide A by Iwona Adwent, Beniamin Oskar Grabarek, Marta Kojs-Mrożkiewicz, Ryszard Brus, Rafał Staszkiewicz, Andrzej Plewka, Michał Stasiowski, Anita Lyssek-Boroń

“…The expression profile of mRNA related to TGFβ paths was indicated by microarray and RTqPCR analyses. The ELISA test was used to analyze changes on the proteome level. …”
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Profiling of Circulating Cell-free DNA Methylation Patterns Identifies Aberrant Methylated CTBP1 Promotor Sites for Prediction of Alzheimer’s Disease by Zhiwu Dong, Kewen Zhao, Hongjun Gu, Wenwei Yang, Xin Zhang

“…The R Bioconductor Linear Models for Microarray Data (LIMMA) package was employed to identify methylation variable positions (MVPs), and Probe Lasso was used to pinpoint differentially methylated regions (DMRs) linked to AD. …”
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Pure Duplication of the Distal Long Arm of Chromosome 15 with Ebstein Anomaly and Clavicular Anomaly by Rachel O'Connor, Amel Al-Murrani, Salim Aftimos, Philip Asquith, Roberto Mazzaschi, Dominique Eyrolle-Guignot, Alice M. George, Donald R. Love

“…This report is of a patient with pure trisomy of 15q24-qter who presents with the rare Ebstein anomaly and a previously unreported skeletal anomaly. Chromosome microarray analysis allowed high-resolution identification of the extent of the trisomy and provided a means of achieving higher-resolution breakpoint data. …”
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Spheroid Culture of Mesenchymal Stem Cells by Zoe Cesarz, Kenichi Tamama

“…Furthermore, spheroid formation causes drastic changes in the gene expression profile of MSC in microarray analyses. In spite of these significant changes, underlying molecular mechanisms and signaling pathways triggering and sustaining these changes are largely unknown.…”
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Exploration of Epigenetic Mechanisms and Biomarkers Among Patients with Very-Late-Onset Schizophrenia-Like Psychosis by Gan Y, Yue W, Sun J, Yang D, Fang C, Zhou Z, Yin J, Zhou H

“…We then collected blood samples from VLOSLP patients and age-matched healthy controls (n = 80) at the Wuxi Mental Health Center for methylation microarray profiling and bisulfite sequencing validation. …”
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Application of family whole-exome sequencing for prenatal diagnosis—an analysis of 357 cases by Yijun Ge, Huizhen Yuan, Yao Yu, Junfang Xiao, Danping Liu, Yongbao Peng, Ying Liu, Shuhui Huang, Bicheng Yang, Yongyi Zou, Yanqiu Liu

“…Using techniques such as amniotic fluid, chorionic villus, or umbilical cord blood sampling, intact fetal cells were extracted for cell culture and subsequently analyzed using chromosomal karyotyping and chromosomal microarray techniques. 2. With fully informed consent, fetuses and their parents whose genetic etiology could not be detected by karyotyping combined with chromosomal microarray technology had their cellular DNA subjected to whole-exome sequencing of the pedigree. 3. …”
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Characterization of a MERS-related betacoronavirus in Danish brown long-eared bats (Plecotus auritus) by Camille Melissa Johnston, Vithiagaran Gunalan, Hans J. Baagøe, Anna S. Fomsgaard, Charlotta Polacek, Morten Rasmussen, Louise Lohse, Thomas Bruun Rasmussen

“…Positive samples underwent ORF1b sequencing, microarray analysis and Illumina MiSeq sequencing, followed by metagenomic assembly of full-length genomes. …”
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Treatment with Rhizoma Dioscoreae Extract Has Protective Effect on Osteopenia in Ovariectomized Rats by Zhiguo Zhang, Lihua Xiang, Dong Bai, Xiaowei Fu, Wenlai Wang, Yan Li, Hong Liu, Jinghua Pan, Ya’nan Li, Gary Guishan Xiao, Dahong Ju

“…Our results show that RDE could inhibit bone loss of OVX rats after a 12-week treatment. The microarray analysis showed that 68 genes were upregulated and that 100 genes were downregulated in femurs of the RDE group rats compared to those in the OVX group. …”
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The liver pharmacological and xenobiotic gene response repertoire by Georges Natsoulis, Cecelia I Pearson, Jeremy Gollub, Barrett P Eynon, Joe Ferng, Ramesh Nair, Radha Idury, May D Lee, Mark R Fielden, Richard J Brennan, Alan H Roter, Kurt Jarnagin

“…Abstract We have used a supervised classification approach to systematically mine a large microarray database derived from livers of compound‐treated rats. …”
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An Ensemble Classification Method for High-Dimensional Data Using Neighborhood Rough Set by Jing Zhang, Guang Lu, Jiaquan Li, Chuanwen Li

“…Efficient and effective sample classification and feature selection are challenging tasks due to high dimensionality and small sample size of microarray data. Feature selection is necessary in the process of constructing the model to reduce time and space consumption. …”
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A systems biology approach to prediction of oncogenes and molecular perturbation targets in B‐cell lymphomas by Kartik M Mani, Celine Lefebvre, Kai Wang, Wei Keat Lim, Katia Basso, Riccardo Dalla‐Favera, Andrea Califano

“…To identify interactions that are dysregulated in three distinct non‐Hodgkin's lymphomas and in samples perturbed with CD40 ligand, we use the B‐cell interactome (BCI), a genome‐wide compendium of human B‐cell molecular interactions, in combination with a large set of microarray expression profiles. The method consistently ranked the known gene in the top 20 (0.3%), outperforming conventional approaches in 3 of 4 cases.…”
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Glucose regulates transcription in yeast through a network of signaling pathways by Shadia Zaman, Soyeon I Lippman, Lisa Schneper, Noam Slonim, James R Broach

“…Abstract Addition of glucose to yeast cells increases their growth rate and results in a massive restructuring of their transcriptional output. We have used microarray analysis in conjunction with conditional mutations to obtain a systems view of the signaling network responsible for glucose‐induced transcriptional changes. …”
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Determination of Viral Nucleic Acid in the Human Blood by M. A. Abdurashitov, N. A. Netesova

“…Methods such as in situ hybridization, reverse transcription reaction (RT-PCR), nested PCR, multiplex PCR, as well as DNA microarray technology, and the method of massive parallel sequencing are considered in detail. …”
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miR-361-5p contributes to the pathogenesis of Alzheimer’s disease by Abbas Jalaiei, Jalal Gharesouran, Shahram Arsang-Jang, Mahnaz Talebi, Maryam Rezazadeh, Soudeh Ghafouri-Fard

“…This study investigated the roles of HOMER1, ATAD1, and miR-361 in AD pathogenesis using microarray (GSE106241, GSE157239; n = 60) and RT-PCR (n = 100; 50 AD patients, 50 controls from Northwest Iran) analyses. …”
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Metabolomic and flux‐balance analysis of age‐related decline of hypoxia tolerance in Drosophila muscle tissue by Laurence Coquin, Jacob D Feala, Andrew D McCulloch, Giovanni Paternostro

“…We expand the reactions in the model using tissue‐ and age‐specific microarray data from the literature, and then examine metabolomic profiles of thoraxes after 4 h at 0.5% O2 and after 5 min of recovery in 40‐ versus 3‐day‐old flies. …”
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Discovering structural cis‐regulatory elements by modeling the behaviors of mRNAs by Barrett C Foat, Gary D Stormo

“…We applied our structural cis‐regulatory element detector (StructRED) to microarray and mRNA sequence data from Saccharomyces cerevisiae, Drosophila melanogaster, and Homo sapiens. …”
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Role of Genetic and Epigenetic Factors and Mechanisms Involved in the Occurrence of Congenital Heart Diseases (CHD) by Fateme Tabrizi, Mehri Khatami, Mohammad Mehdi Heidari

“…Advanced research in molecular genetics, especially techniques such as whole-exome sequencing and chromosomal microarray analysis, which focus on protein-coding regions of the human genome, has identified hundreds of genes associated with the development of CHD. …”
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Pairing of competitive and topologically distinct regulatory modules enhances patterned gene expression by Itai Yanai, L Ryan Baugh, Jessica J Smith, Casey Roehrig, Shai S Shen‐Orr, Julia M Claggett, Andrew A Hill, Donna K Slonim, Craig P Hunter

“…We used RNAi and time series, whole‐genome microarray analyses to systematically perturb and characterize components of a Caenorhabditis elegans lineage‐specific transcriptional regulatory network. …”
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Probing the microRNA landscape in cadmium chloride induced renal toxicity through an in silico approach by Arnab Mukherjee, Sai Eashan Vankamamidi, Mukunthan KS

“…These non-coding RNAs regulate gene expression by promoting mRNA degradation and translational repression. In this study, microarray data from HK-2 cells exposed to CdCl₂ was analyzed, revealing increased oxidative stress and disrupted mitochondrial function. …”
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