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461
Cyclooxygenase 2 (COX2) and Peroxisome Proliferator-Activated Receptor Gamma (PPARG) Are Stage-Dependent Prognostic Markers of Malignant Melanoma
Published 2010-01-01“…Using tissue microarrays (TMAs) we studied COX2/PPARG immunoreactivity in a broad spectrum of tumors focussing on clinicopathological correlations and the outcome of patients with malignant melanoma (MM). …”
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462
Identification of TTLL8, POTEE, and PKMYT1 as immunogenic cancer-associated antigens and potential immunotherapy targets in ovarian cancer
Published 2025-12-01“…From this dataset, we identified TTLL8, POTEE, and PKMYT1 peptides as candidate tumor antigens with low expression in normal tissues and upregulated expression in OC. Using tissue microarrays, we assessed the protein expression of TTLL8 and POTEE and their association with patient outcomes in a large cohort of OC patients. …”
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463
Application of reproductive technologies to the improvement of dairy cattle genomic selection
Published 2015-07-01“…The main trends in the development of genomic selection include improvement of the accuracy of breeding value estimations by combination of reference populations; use genotyping of cows in breeding programs; imputation of genotypes for absent SNPs with low marker density microarrays, and prediction of animal genotypes from the genotypes of relatives. …”
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464
Blood Transcriptional Signatures for Disease Progression in a Rat Model of Osteoarthritis
Published 2017-01-01“…We used whole-genome microarrays to reveal OA-related transcriptional alterations of 72 transcripts. …”
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465
GADD45β Determines Chemoresistance and Invasive Growth of Side Population Cells of Human Embryonic Carcinoma
Published 2010-01-01“…To further characterize the NEC8 SP cells, we used DNA microarrays. Among 38,500 genes, we identified 12 genes that were over-expressed in SP cells and 1 gene that was over-expressed in non-SP cells. …”
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466
TGFβ1-Induced Differentiation of Human Bone Marrow-Derived MSCs Is Mediated by Changes to the Actin Cytoskeleton
Published 2018-01-01“…To identify the mechanisms underlying this TGFβ-mediated enhancement of lineage commitment, we compared the gene expression profiles of TGFβ1-treated hMSC cultures using DNA microarrays. In total, 1932 genes were upregulated, and 1298 genes were downregulated. …”
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467
Pancreatic Acinar Cells Employ miRNAs as Mediators of Intercellular Communication to Participate in the Regulation of Pancreatitis-Associated Macrophage Activation
Published 2016-01-01“…Exosomal miRNAs were extracted and examined using microarrays. A total of 115 differentially expressed miRNAs were identified, and 30 showed upregulated expression, while 85 displayed downregulated expression. …”
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468
Immunohistochemical Expression of Dual-Specificity Protein Phosphatase 4 in Patients with Colorectal Adenocarcinoma
Published 2015-01-01“…We constructed tissue microarrays and investigated DUSP4 expression by immunohistochemistry. …”
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469
Soil-Borne Microbial Functional Structure across Different Land Uses
Published 2014-01-01“…In a multivariate regression tree analysis of soil physicochemical properties and genes detected by functional microarrays, the main factor that explained the different microbial community functional structures was C : N ratio. …”
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470
A new dimensionality reduction technique based on the Wavelet Transform for cancer classification
Published 2025-01-01“…Although the advent of methylation microarrays such as the HumanMethylation450 platform has greatly reduced the dimensionality of the problem from billions to 450K positions, this data size is still too large to be processed by machine learning algorithms for cancer prediction and classification. …”
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471
Involvement of circRNAs in Proinflammatory Cytokines-Mediated β-Cell Dysfunction
Published 2021-01-01“…Methods. circRNA expression profile of MIN6 cells stimulated with a mix of cytokines, including IL-1β, IFN-γ, and TNF-α, was detected by circRNA microarrays. Four dysregulated circRNAs were validated by qRT-PCR. …”
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472
Cyclooxygenase-2 Expression Is a Predictive Marker for Late Recurrence in Colorectal Cancer
Published 2018-01-01“…Immunohistochemical staining, performed for the presence of COX-2 on tissue microarrays, was analyzed. Results. Forty-six patients showed elevated COX-2 expression, and 52 patients did not. …”
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473
History and prospects of flax genetic markers
Published 2025-01-01“…Cost-effective and accurate analysis of large number of genotypes for multiple markers simultaneously using microarrays or targeted deep sequencing became available, as well as HRM, TaqMan, KASP, and other fluorescence-based high-throughput methods for detecting DNA polymorphisms. …”
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474
Quantifying intratumoral biomarker heterogeneity in tubo-ovarian high-grade serous carcinoma to optimize clinical translation
Published 2025-01-01“…Markers were stained on tissue microarrays and scored using a continuous or categorical interpretation of staining patterns. …”
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475
MicroRNA-208a Dysregulates Apoptosis Genes Expression and Promotes Cardiomyocyte Apoptosis during Ischemia and Its Silencing Improves Cardiac Function after Myocardial Infarction
Published 2015-01-01“…Differential gene expression was assessed using microarrays. MI was induced in male C57BL/6 mice randomly assigned to antagomir (n=6) or control group (n=7), while sham group (n=7) had sham operation done. …”
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476
The future of plant lectinology: Advanced technologies and computational tools
Published 2025-01-01“…Techniques such as glycan microarrays allow rapid assessment of lectin specificity across a diverse range of glycans by evaluating interactions with immobilized glycans on solid surfaces. …”
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477
Surface Modification by Combination of Dip-Pen Nanolithography and Soft Lithography for Reduction of Bacterial Adhesion
Published 2018-01-01“…DPN allowed creating microarrays from 1 to 5 µm in diameter on model surfaces that were successfully transferred to the stainless steel 316L surface via microstamping. …”
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478
miRNA Expression Profile and Effect of Wenxin Granule in Rats with Ligation-Induced Myocardial Infarction
Published 2017-01-01“…MI rat model was established by a coronary artery ligation surgery. miRNA expression microarrays were performed and the data were deposited in Gene Expression Omnibus (GEO number GSE95855). …”
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479
ATG5 and ATG7 Expression Levels Are Reduced in Cutaneous Melanoma and Regulated by NRF1
Published 2021-08-01“…We investigated the expression of ATG proteins in benign nevi, primary and metastatic melanoma tissues using customized tissue microarrays (TMA). Results from immunohistochemistry show that the expression of ATG5 and ATG7 is significantly reduced in melanoma tissues compared to benign nevi. …”
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480
Spatial profiling of endoplasmic reticulum stress markers in tumor associated cells predicts patient outcomes in pancreatic cancer
Published 2025-02-01“…Methods: Multiplex immunofluorescence was performed on tumor microarrays and images were analyzed using HALO AI software. …”
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