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Computer analysis shows differences between mitochondrial miRNAs and other miRNAs
Published 2025-01-01“…A subclass of miRNAs with as yet unknown specific functions is mitomiRs – mitochondrial miRNAs that are mainly derived from nuclear DNA and are imported into mitochondria; moreover, changes in the expression levels of mitomiRs are associated with some diseases. …”
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Regulation of miRNAs in obesity and diabetes
Published 2023-12-01“…The identification of dysregulated miRNAs and in particular novel dysregulated miRNAs, may lead to the development of miRNA-based personalised therapeutics for obesity and diabetes.…”
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Use of miRNAs as Biomarkers in Sepsis
Published 2015-01-01“…Recent studies highlight the use of new biomarkers for sepsis, namely, miRNAs. miRNAs belong to a class of small, noncoding RNAs with an approximate content of 19–23 nucleotides. …”
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miRNAs and Melanoma: How Are They Connected?
Published 2012-01-01“…miRNAs are non-coding RNAs that bind to mRNA targets and disturb their stability and/or translation, thus acting in gene posttranscriptional regulation. …”
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Modulation of miRNAs in Pulmonary Hypertension
Published 2015-01-01“…MicroRNAs (miRNAs) have emerged as a new class of posttranscriptional regulators of many cardiac and vascular diseases. …”
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Base Composition Characteristics of Mammalian miRNAs
Published 2013-01-01“…MicroRNAs (miRNAs) are short RNA sequences that repress protein synthesis by either inhibiting the translation of messenger RNA (mRNA) or increasing mRNA degradation. …”
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鼻咽癌差异表达miRNAs筛选研究
Published 2007-01-01“…【目的】应用miRNAs芯片筛选原代培养的鼻咽癌细胞差异表达miRNAs,并寻找差异表达miRNAs调控的靶基因,为进一步研究其在鼻咽癌发病机制中的作用打下基础。…”
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Mechanism and Therapeutic Prospect of miRNAs in Neurodegenerative Diseases
Published 2023-01-01“…MicroRNAs (miRNAs) are the smallest class of noncoding RNAs, which widely exist in animals and plants. …”
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Identification of Aberrantly Expressed miRNAs in Gastric Cancer
Published 2014-01-01“…It is necessary to identify novel aberrantly expressed miRNAs in gastric cancer. In this study, the expression profile of 1891 miRNAs was analyzed using a miRCURY array LNA miRNA chip from three gastric cancer tissues and three normal tissues. …”
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The context signals of mitochondrial miRNAs (mitomiRs) of mammals
Published 2023-01-01“…MicroRNAs (miRNAs) are small non-coding RNAs that regulate gene expression at the post-transcriptional level in the cytoplasm and play an important role in a wide range of biological processes. …”
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Bioinformatics analysis of miRNAs germacrone protection on diabetic nephropathy
Published 2024-12-01“…Based on our results, we found 23 miRNAs were differentially expressed in the DN group compared to the controls, and a total of 14 miRNAs were differentially expressed between the DN group and the germacrone-treated group. …”
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The Role of miRNAs in the Regulation of Pancreatic Cancer Stem Cells
Published 2016-01-01“…In this review, we synthesize the latest findings on the role of miRNAs in regulating different biological properties of pancreatic cancer stem cells.…”
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Preeclampsia, Natural History, Genes, and miRNAs Associated with the Syndrome
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Exosomal miRNAs involvement in pathogenesis, diagnosis, and treatment of rheumatoid arthritis
Published 2025-01-01“…Furthermore, circulating exosomal miRNAs were introduced as available diagnostic and prognostic biomarkers for RA pathology. …”
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Research Progress on Natural Products That Regulate miRNAs in the Treatment of Osteosarcoma
Published 2025-01-01“…miRNAs are small non-coding RNA molecules that play critical roles in the regulation of gene expression and have been closely associated with various diseases, including cancer. …”
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The Role of miRNAs as Biomarkers for Pregnancy Outcomes: A Comprehensive Review
Published 2017-01-01“…This study has the aim to provide a comprehensive review on the role of miRNAs as potential biomarkers for adverse pregnancy outcomes and prenatal environmental exposure.…”
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miRNAs Participate in MS Pathological Processes and Its Therapeutic Response
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The Emerging Role of miRNAs and Their Clinical Implication in Biliary Tract Cancer
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Integrated analysis of miRNAs and mRNAs in thousands of single cells
Published 2025-01-01“…PSCSR-seq V2 offers unique functionality to users conducting functional studies of miRNAs in clinical and basic biological research.…”
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Epigenetic modifications in bladder cancer: crosstalk between DNA methylation and miRNAs
Published 2025-02-01“…Consequently, this work aims to explore the interaction mechanisms between DNA methylation and miRNAs in the occurrence and development of BC. Research has demonstrated that DNA methylation not only directly influences the expression of miRNA genes but also indirectly affects the maturation and functionality of miRNAs by modulating the methylation status of miRNA promoter regions. …”
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