Crosstalk between non-coding RNAs and programmed cell death in colorectal cancer: implications for targeted therapy by Seyed Reza Taha, Mehdi Karimi, Bahar Mahdavi, Milad Yousefi Tehrani, Ali Bemani, Shahriar Kabirian, Javad Mohammadi, Sina Jabbari, Meysam Hushmand, Alireza Mokhtar, Mohammad Hossein Pourhanifeh

“…Non-coding RNAs (ncRNAs), including microRNAs (miRNAs), long non-coding RNAs (lncRNAs), and circular RNAs (circRNAs), have been identified as key regulators of gene expression, affecting diverse biological processes, notably programmed cell death (PCD). …”
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Upregulated miR-206 Aggravates Deep Vein Thrombosis by Regulating GJA1-Mediated Autophagy of Endothelial Progenitor Cells by Yan Li, Jingping Ge, Yuanyuan Yin, Ruowen Yang, Jie Kong, Jianping Gu

“…Deep vein thrombosis (DVT) is the third most prevalent vascular disease worldwide. MicroRNAs (miRNAs) play regulatory roles in functions of endothelial progenitor cells (EPCs), which is becoming a promising therapeutic choice for thrombus resolution. …”
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Deregulation mechanisms and therapeutic opportunities of p53-responsive microRNAs in diffuse large B-cell lymphoma by Elena N. Voropaeva, Yuriy L. Orlov, Anastasia B. Loginova, Olga B. Seregina, Vladimir N. Maksimov, Tatiana I. Pospelova

“…We overview the studies on the role of miRNAs in regulating gene expression associated with tumorigenesis processes, with particular emphasis on their role as tumor growth-suppressing factors. …”
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Unveiling the potential anticancer activity of Spirulina maxima extract-nanoemulsion through in vitro and in vivo studies by Mohammed Yasser Hussein, Merna Nasr, Veronia Emad, Julie Maged, Portia George, Amina Emad, Abeer Mahmoud Badr, Mehrez E. El-Naggar, Sayeda M. Abdo, Jihan Hussein

“…The study concludes that SMNE, with its anti-inflammatory and antioxidant properties and ability to modulate key miRNAs, enhances SME delivery and shows promise as an effective cancer treatment.…”
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The Central Roles of Noncoding RNA in Estrogen-Dependent Female Reproductive System Tumors by Jiajie Tu, Huan Yang, Lei Jiang, Yu Chen, Yu Chen, Zhe Li, Lei Li, Yuanyuan Zhang, Xiaochun Chen, He Chen, Zhiying Yu

“…Noncoding RNAs (ncRNAs) are defined as RNAs that do not encode proteins, including microRNAs (miRNAs) and long noncoding RNAs (lncRNAs), both of which have been reported in estrogen-dependent female reproductive system tumors. …”
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Antidepressant Treatment Response Prediction With Early Assessment of Functional Near-Infrared Spectroscopy and Micro-RNA by Lok Hua Lee, Cyrus Su Hui Ho, Yee Ling Chan, Gabrielle Wann Nii Tay, Cheng-Kai Lu, Tong Boon Tang

“…To address this, the aim of the current study is to investigate MDD ATR at three response levels using fNIRS and micro-ribonucleic acids (miRNAs). Our proposed algorithm includes a custom inter-subject variability reduction based on the principal component analysis (PCA). …”
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Circulating miRNA-125b Is a Potential Biomarker Predicting Response to Rituximab in Rheumatoid Arthritis by Isabelle Duroux-Richard, Yves-Marie Pers, Sylvie Fabre, Meryem Ammari, Dominique Baeten, Guillaume Cartron, Isabelle Touitou, Christian Jorgensen, Florence Apparailly

“…Although biologic therapies have changed the course of rheumatoid arthritis (RA), today’s major challenge remains to identify biomarkers to target treatments to selected patient groups. Circulating micro(mi)RNAs represent a novel class of molecular biomarkers whose expression is altered in RA. …”
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Identification and Analysis of Circular RNAs in Mammary Gland from Yaks Between Lactation and Dry Period by Yilin Shi, Xiaoyun Wu, Guangyao Meng, Xiaoming Ma, Yongfu La, Pengjia Bao, Min Chu, Ping Yan

“…Circular RNA (circRNA), a non-coding RNA, acts as a molecular sponge that sequesters microRNAs (miRNAs) to regulate target gene expression. Although circRNA has been linked to mammary gland lactation, its specific role in yaks remains underexplored. …”
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Inflammation and Immune Escape in Ovarian Cancer: Pathways and Therapeutic Opportunities by Liu C, Yin Q, Wu Z, Li W, Huang J, Chen B, Yang Y, Zheng X, Zeng L, Wang J

“…Additionally, emerging research on the microbiome and inflammation-related biomarkers, such as microRNAs (miRNAs) and exosomes, points to new opportunities for early detection and precision medicine. …”
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Identification and analysis of pancreatic intraepithelial neoplasia: opportunities and challenges by Ling-ling Pian, Ling-ling Pian, Mei-hui Song, Teng-fei Wang, Teng-fei Wang, Ling Qi, Tie-li Peng, Ke-ping Xie

“…In addition, metabolomics technologies and miRNAs are playing an increasingly important role in the field of cancer diagnosis, offering more possibilities for efficient identification of PanIN. …”
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Construction and Investigation of MicroRNA-mRNA Regulatory Network of Gastric Cancer with Helicobacter pylori Infection by Ping Yang, Junjie Liu, Tianci Yang, Lei Zhang, Peiyou Gong, Boqing Li, Xiuzhi Zhou

“…Results. 22 DEMs and 68 DEGs were identified in GSE197694 and GSE27411 dataset. 16 miRNAs and 509 genes were involved in the expression network, while the cross-genes of the network were mainly enriched in MAP kinase (MAPK) signaling pathway and TGF-beta signaling pathway. …”
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Argonaute2 modulates megakaryocyte development and sex-specific control of platelet protein expression and reactivity by Sophia Lazar, Jeremy G.T. Wurtzel, Shayan Askari, Matthew Cooper, Xuefei Zhao, Peisong Ma, Lawrence E. Goldfinger

“…Abstract Platelets are enriched in miRNAs and harbor Ago2 as the principal RNA silencing Argonaute. …”
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Role of Sex Hormones in the Development and Progression of Hepatitis B Virus-Associated Hepatocellular Carcinoma by Maurizio Montella, Giovanni D’Arena, Anna Crispo, Mario Capunzo, Flavia Nocerino, Maria Grimaldi, Antonio Barbieri, Anna Maria D’Ursi, Mario Felice Tecce, Alfonso Amore, Massimiliano Galdiero, Gennaro Ciliberto, Aldo Giudice

“…Additionally, sex hormones can also affect HBV-related hepatocarcinogenesis by inducing epigenetic changes such as the regulation of mRNA levels by microRNAs (miRNAs), DNA methylation, and histone modification in liver tissue. …”
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Analysis of the lncRNA-Associated Competing Endogenous RNA (ceRNA) Network for Tendinopathy by Bing-Zhe Huang, Yang Jing-Jing, Xiao-Ming Dong, null Zhuan Zhong, null Xiao-Ning Liu

“…The ceRNA network contained 7 lncRNAs (MIR133A1HG, LINC01405, PRKCQ-AS1, C10orf71-AS1, MBNL1-AS1, HOTAIRM1, and DNM3OS), 63 mRNAs, and 41 miRNAs. Downregulated lncRNA MIR133A1HG could competitively bind with hsa-miR-659-3p and hsa-miR-218-1-3p to regulate the TPM3. …”
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CircRNAs in colorectal cancer: potential roles, clinical applications, and natural product-based regulation by Jingjing Yang, Jingjing Yang, Qiqi Fan, Yiyun Wang, Yuanyue Liu, Xiaoning Xu, Yeqi Liang, Jiakang Xie, Jiajie Li, Fengting Ai, Yong Cao, Shangzhen Yu, Jinman Liu

“…CircRNAs regulate tumor-related signaling pathways through interactions with microRNAs (miRNAs) and proteins, playing key roles in tumorigenesis, progression, invasion, metastasis, and chemoresistance. …”
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Transcriptomic Response of Arabidopsis thaliana to Pseudomonas syringae Infection: An In Silico Approach by Amir Ghaffar Shahriari, Mohamad Hamed Ghodoum Parizipour, Yaser Biniaz, Aminallah Tahmasebi, Fatemeh Gholizadeh

“…Also, critical factors, including hub genes, protein-protein interaction (PPI), and micro RNAs (miRNAs), were analyzed. A total number of 22 biological pathways were significantly enriched with up-/down-regulated differentially expressed genes (DEGs) in the Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis. …”
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<i>Lin28b-let-7</i> Modulates mRNA Expression of <i>GnRH1</i> Through Multiple Signaling Pathways Related to Glycolysis in GT1-7 Cells by Yujing Xie, Xin Li, Meng Wang, Mingxing Chu, Guiling Cao

“…Additionally, 77 differentially expressed miRNAs (DEMIs) in <i>Lin28b</i>-overexpressed GT1-7 cells were identified. …”
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Circ_0044516 Regulates miR-136/MAT2A Pathway to Facilitate Lung Cancer Development by Yue-Wei Chen, Qiu-Rong Du, Yu-Juan He, Wen-Shu Chen, Wen-Yang Jiang, Qi Gui, Cheng-Cheng Xu, Wei Wang, Hong-Yun Cheng

“…Circular RNA (circRNA) is a type of noncoding RNA that can interact with miRNAs to regulate gene expression. However, little is known concerning circRNA, which is crucial in the pathogenesis of lung cancer. …”
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Clinical Role of Epigenetics and Network Analysis in Eye Diseases: A Translational Science Review by Michele Lanza, Giuditta Benincasa, Dario Costa, Claudio Napoli

“…A large panel of upregulated micro-RNAs (miRNAs), including hsa-hsa-miR-494, hsa-let-7e, hsa-miR-513-1, hsa-miR-513-2, hsa-miR-518c, hsa-miR-129-1, hsa-miR-129-2, hsa-miR-198, hsa-miR-492, hsa-miR-498, hsa-miR-320, hsa-miR-503, and hsa-miR-373,∗ may have a putative role in the development of retinoblastoma. …”
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The emerging role of blood-based biomarkers in early detection of colorectal cancer: A systematic review by Faris Shweikeh, Yuhao Zeng, Abdur Rahman Jabir, Erica Whittenberger, Saurav P. Kadatane, Yuting Huang, Mohamad Mouchli, Dani Ran Castillo

“…For instance, methylation patterns in genes such as MYO1-G and NDRG4 exhibited high diagnostic accuracies with AUCs reaching up to 0.996. RNA biomarkers like miRNAs and circRNAs also showed promising results, with circ_0011536 achieving AUCs of 0.982. …”
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