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441
Long noncoding RNAs predict the survival of patients with colorectal cancer as revealed by constructing an endogenous RNA network using bioinformation analysis
Published 2019-03-01“…The RNA sequencing profiles of patients with colorectal cancer were downloaded from TCGA database, and 62 lncRNAs, 30miRNAs, and 59 mRNAs were identified to comprise the ceRNA network (fold change > 2, P < 0.01). …”
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442
Endothelial Cell-Derived Extracellular Vesicles Target TLR4 via miRNA-326-3p to Regulate Skin Fibroblasts Senescence
Published 2022-01-01“…Real-time PCR was applied to assay miRNAs and mRNAs expressions. Western blot was used to detect TLR4 protein expression. …”
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443
WWTR1-AS1 LncRNA as a Novel Potential Diagnostic and Prognostic Biomarker in Breast Cancer
Published 2024-02-01“…Proteomic analysis recognized 1149 differential expressed proteins in breast cancer with regulatory agents consisting of 76 TFs, 61 kinases, 366 miRNAs, and 162 lncRNAs. A multi-regulatory network with 1811 nodes and 4022 edges was constructed based on differentially expressed proteins and their associated elements. …”
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444
Exploring serum miR-33b as a novel diagnostic marker for hypercholesterolemia and obesity: insights from a pilot case-control study
Published 2025-01-01“…Abstract Obesity and atherosclerosis are significant metabolic diseases characterized by disrupted lipid metabolism. MicroRNAs (miRNAs) are small, conserved, non-coding RNA sequences consisting of approximately 22 nucleotides, playing crucial roles in biological and pathological functions. …”
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445
MiR-25-3p regulates pulmonary arteriovenous malformation after Glenn procedure in patients with univentricular heart via the PHLPP2-HIF-1α axis
Published 2025-02-01“…In addition, we investigated the tube formation, migration, and proliferation of human lung microvascular endothelial cells (HMVEC-L) transfected with miR-25-3p mimic, miR-25-3p inhibitor, or PHLPP2 small interfering RNA, and examined HIF-1α/VEGF-A signaling after hypoxic stimulation. Serum miRNAs that showed ≥ 2-fold higher levels in patients with G-PAVMs than in other patients were selected. …”
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446
MicroRNA-223 Expression Is Upregulated in Insulin Resistant Human Adipose Tissue
Published 2015-01-01“…MicroRNAs (miRNAs) are short noncoding RNAs involved in posttranscriptional regulation of gene expression and influence many cellular functions including glucose and lipid metabolism. …”
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447
Comparative analysis of the profile of circulating microRNAs in the blood plasma of patients with gliomas
Published 2024-06-01“…Endogenous noncoding miRNAs that regulate the expression of target mRNAs have become attractive targets for the development of circulating biomarker-based assays, because sample acquisition does not require invasive sampling such as biopsy.Purpose of the study. …”
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448
Identification and Validation of the Pyroptosis-Related Hub Gene Signature and the Associated Regulation Axis in Diabetic Keratopathy
Published 2024-01-01“…A competing endogenous RNA network comprising 16 DEPRGs, 22 lncRNAs, 13 miRNAs, and 3 circRNAs was constructed. After PPI network, five hub genes (Nfkb1, Casp8, Traf6, Ptgs2, and Il18) were identified as upregulated in the diabetic group, and their expression was validated by RT-qPCR in streptozocin-induced rats. …”
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449
Effect of miR-1285-3p as a diagnostic biomarker for chronic heart failure on vascular endothelial cells
Published 2025-01-01“…Abstract Background MicroRNAs (miRNAs) are closely related to cardiovascular diseases, including chronic heart failure (CHF). …”
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450
Effect of miR-223-3p and miR-328a-3p Knockdown on Allergic Airway Inflammation in Rat Precision-Cut Lung Slices
Published 2025-01-01“…Our study highlighted some important issues: the need to extend the model by including more biological replicates, the need to standardize culture conditions, and the need to consider co-transfection with several miRNA inhibitors when modifying miRNAs expression in the PCLS model.…”
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451
Molecular Signature of miR-34a/NEAT-1/p53 Axis in Mycosis Fungoides
Published 2024-01-01“…Understanding the role of miRNAs and ncRNAs in p53-response has become an open discussion, as they can regulate p53 or its downstream targets, and ncRNAs themselves. …”
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452
Maintenance of Self-Renewal and Pluripotency in J1 Mouse Embryonic Stem Cells through Regulating Transcription Factor and MicroRNA Expression Induced by PD0325901
Published 2016-01-01“…Moreover, PD can significantly modulate the expressions of multiple miRNAs that have crucial functions in ESC development. …”
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453
lncRNA IGHCγ1 Acts as a ceRNA to Regulate Macrophage Inflammation via the miR-6891-3p/TLR4 Axis in Osteoarthritis
Published 2020-01-01“…Accumulating data have implicated that long noncoding RNA (lncRNA) plays an important role in osteoarthritis (OA), which may function as a competitive endogenous RNA (ceRNA) of microRNAs (miRNAs). lncRNA IGHCγ1 has been demonstrated to regulate inflammation and autoimmunity. …”
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454
MicroRNA-Based Markers of Oral Tongue Squamous Cell Carcinoma and Buccal Squamous Cell Carcinoma: A Systems Biology Approach
Published 2023-01-01“…Orthogonal partial least square (OPLS) analysis identified common differentially expressed miRNAs (DEMs) in OTSCC and BSCC compared to their adjacent normal mucosa. …”
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455
Identification of important genes related to ferroptosis in early missed abortion based on WGCNA
Published 2025-01-01“…However, the interacting miRNAs predicted for SLC3A2 in the miRanda, miRDB, and TargetScan databases were limited to hsa-miR-661 and hsa-miR-4311, with no interacting lncRNAs found in the spongeScan database. …”
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456
Mir-615-5p inhibits cervical cancer progression by targeting TMIGD2
Published 2025-01-01“…Abstract Background Cervical cancer (CC) is a prevalent gynecological malignancy, contributing to a substantial number of fatalities among women. MicroRNAs (miRNAs) have emerged as promising biomarkers with significant potential for the early detection and prognosis of CC. …”
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457
Macrophage Infiltration and ITGB2 Expression in ESCC: A Novel Correlation
Published 2025-01-01“…Furthermore, we identified three miRNAs associated with abnormal ITGB2 expression, providing insights into the upstream molecular interactions of ITGB2. …”
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458
Chromosome-level genome assembly and annotation of Barbel chub Squaliobarbus curriculus
Published 2024-12-01“…Additionally, we annotated 2,041 miRNAs, 16,426 tRNAs, 5,488 rRNAs and 1,536 snRNAs in the S. curriculus genome. …”
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459
Expression of some circulating microRNAs as predictive biomarkers for prognosis and treatment response in glioblastoma
Published 2025-01-01“…Therefore, new insights into GBM management are urgently needed to increase the chance of therapeutic success. Circulating miRNAs (miRs) are important regulators of cancer progression and are potentially useful for GBM diagnosis and treatment. …”
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460
MicroRNA as a Potential Diagnostic and Prognostic Biomarker in Diffuse Large B‐Cell Lymphoma: A Systematic Review and Meta‐Analysis
Published 2025-01-01“…ABSTRACT Background Recently, microRNAs (miRNAs) have been applied as biomarkers for diffuse large B‐cell lymphoma (DLBCL) patients. …”
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