The Diagnostic and Predictive Significance of Immune-Related Genes and Immune Characteristics in the Occurrence and Progression of IgA Nephropathy by Jian-Bo Qing, Wen-Zhu Song, Chang-Qun Li, Ya-Feng Li

“…A ceRNA network associated with IgAN progression which contained 8 miRNAs, 14 lncRNAs, and 3 mRNAs was established. A higher macrophage ratio and lower CD4+ T cell ratio in IgAN compared to controls were observed, and the correlation between macrophages and monocytes in the glomeruli of IgAN patients was inverse compared to controls. …”
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Comparison of Proangiogenic Effects of Adipose-Derived Stem Cells and Foreskin Fibroblast Exosomes on Artificial Dermis Prefabricated Flaps by Jiachao Xiong, Zhixiao Liu, Minliang Wu, Mengyan Sun, Yu Xia, Yuchong Wang

“…NGS indicated that there were some differentially expressed miRNAs in both exosomes. Bioinformatics analysis suggested that significantly upregulated hsa-miR-760 and significantly downregulated hsa-miR-423-3p in ADSC-Exo could regulate the expression of the ITGA5 and HDAC5 genes, respectively, to promote the vascularization of skin flaps. …”
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miR-224 activates cancer-associated fibroblasts to enhance lung cancer cell migration and invasion by targeting Akirin1 by Seonyeong Oh, Sieun Lee, Inyoung Cheon, Young-Ho Ahn

“…This study utilized global microRNA (miRNA) expression profiling to identify specific miRNAs responsible for reprogramming normal lung fibroblasts (LFs) into CAFs. miR-224 demonstrates increased expression in CAFs, and its levels are elevated in lung tumors compared to those in normal tissues, according to data from public databases. …”
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The relationship of lamins with epigenetic factors during aging by R. N. Mustafin, E. K. Khusnutdinova

“…There is also an inverse regulation, since transposons are sources of miRNAs that affect lamins. We suggest that lamins can be attributed to epigenetic factors, since they are part of the NURD, interact with histone deacetylases and regulate gene expression without changing the nucleotide sequences. …”
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Exercise-induced extracellular vesicles in reprogramming energy metabolism in cancer by Marju Puurand, Alicia Llorente, Alicia Llorente, Alicia Llorente, Aija Linē, Tuuli Kaambre

“…By transferring bioactive cargo such as miRNAs, proteins and metabolites, exercise-induced EVs may influence cancer cells by altering glycolysis and oxidative phosphorylation, potentially shifting metabolic plasticity – a hallmark of cancer. …”
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Comprehensive RNA-seq analysis of benign prostatic hyperplasia (BPH) in rats exposed to testosterone and estradiol by Xiao-Hu Tang, Zhi-Yan Liu, Jing-Wen Ren, Heng Zhang, Ye Tian, Jian-Xin Hu, Zhao-Lin Sun, Guang-Heng Luo

“…DEGs were also regulated by 250 miRNAs. In conclusion, we built a novel T + E2-induced rat BPH model, and discovered potentially important genes, pathways, and miRNA-mRNA regulatory networks.…”
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The role of microRNAs in learning and long-term memory by L. N. Grinkevich

“…It describes microRNA biogenesis and the role of miRNAs in the regulation of gene expression, as well as the latest achievements in studying the functional role of microRNAs in learning and in long-term memory formation, depending on the activation or inhibition of their expression. …”
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Bioinformatic Prediction of Novel microRNAs Encoded in Krüppel-like Factor 4 Gene by Mina Zahiri, Maryam Hassanlou, Amir-Reza Javanmard, Nooshin Bijari

“…The UCSC database assessed the conservation status of these miRNAs and their precursors. From the results of bioinformatics analysis of KLF4 gene, three microRNAs were predicted. …”
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Flavonoids as Strong Inhibitors of MAPK3: A Computational Drug Discovery Approach by Amir Taherkhani, Parita Khodadadi, Lida Samie, Zahra Azadian, Zeynab Bayat

“…Negative regulation of MAPK3 expression using miRNAs has led to therapeutic effects in cancer. Objectives. …”
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Bioinformatics analysis of mitochondrial metabolism-related genes demonstrates their importance in renal cell carcinoma by Mohsen Ahmadi, Maryam Motallebinezhad, Pegah Mousavi, Amir Hossein Miladipour, Shamim Fooladgar, Soudeh Ghafouri-Fard, Seyed Amirhossein Fazeli

“…We also investigated gene interaction with miRNAs and immune infiltration analysis. Results Through these steps, we provided a list of possible diagnostic markers and therapeutic targets for ccRCC. …”
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Study on the Correlation between Interleukin-27 and CXCL10 in Pulmonary Tuberculosis by Jiahui Fan, Yefeng Yang, Liang Wang, Xiaoqian Shang, Li Zhang, Hu Sun, Yujie Ma, Ying Li, Jing Wang, Xiumin Ma

“…To investigate the correlation between interleukin-27 and CXCL10 and other cytokines in pulmonary tuberculosis and to further explore the related miRNAs through bioinformatics. Methods. Collect the lesion tissue and peripheral blood of pulmonary tuberculosis patients and the peripheral blood of healthy controls. …”
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Clinical value of miR-200b in diagnosis and prognosis of childhood pneumonia by Weiwei Qi, Beibei Teng, Fan Zhang, Ying Chen, Jinmei Xu, Jinling Luan

“…However, differential changes in miRNAs may interact with the regulation of CP. The aim of this paper was to discuss the miR-200b expression in CP and its diagnostic and prognostic value. …”
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Identification of biomarkers associated with ferroptosis in macrophages infected with Mycobacterium abscessus using bioinformatic tools. by Jiahua Qian, Chenghua Lu, Kai Meng, Zhihong Xu, Honghao Xue, Weijie Yang

“…The RBP-mRNA network highlighted significant interactions between hub genes and key RNA-binding proteins, while the ceRNA network predicted that miRNAs and lncRNAs regulate ferroptosis-related genes NACC2 and ITPKB. …”
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The Potential Diagnostic Value of Immune-Related Genes in Interstitial Fibrosis and Tubular Atrophy after Kidney Transplantation by Bin Yang, Dike Shi, Yahong Chen, Yi Zhu

“…Finally, we found multiple miRNAs that could regulate diagnostic genes from the ceRNA network. …”
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T Cell Subsets and the Expression of Related MicroRNAs in Patients with Recurrent Early Pregnancy Loss by Ya-ni Yan, Jian Zhang, Na Yang, Chaochao Chen, Weiwei Li

“…The expression levels of T cell subset-related markers and T cell subset-related miRNAs, in addition to the frequencies of T cell subsets, in peripheral blood of the two groups were analyzed. …”
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Extracellular Vesicle-Encapsulated MicroRNA-375 from Bone Marrow-Derived Mesenchymal Stem Cells Inhibits Hepatocellular Carcinoma Progression through Regulating HOXB3-Mediated Wnt/... by Zhaoxia Yu, Ju Liu, Qiqi Fan, Jun Yu, Xiaoting Ren, Xiaobin Wang

“…Nowadays, microRNA-375 (miR-375) has been implicated in many types of cancers, including hepatocellular carcinoma (HCC), and the functions of miRNAs encapsulated by extracellular vesicles (EV) in HCC progression have also been extensively investigated. …”
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miR-449a/miR-340 reprogram cell identity and metabolism in fusion-negative rhabdomyosarcoma by Enrico Pozzo, Laura Yedigaryan, Nefele Giarratana, Chao-chi Wang, Gabriel Miró Garrido, Ewoud Degreef, Vittoria Marini, Gianmarco Rinaldi, Bernard K. van der Veer, Gabriele Sassi, Guy Eelen, Mélanie Planque, Alessandro Fanzani, Kian Peng Koh, Peter Carmeliet, Jason T. Yustein, Sarah-Maria Fendt, Anne Uyttebroeck, Maurilio Sampaolesi

“…In this study, we identify miRNAs impacting FN-RMS cell identity, revealing miR-449a and miR-340 as major regulators of the cell cycle and p53 signaling. …”
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METTL1 coordinates cutaneous squamous cell carcinoma progression via the m7G modification of the ATF4 mRNA by Xinru Zhang, Tong Chen, Fanrong Zhang, Huanhuan Shi, Xiang Li, Zhijuan Wang, Dong Wang, Chao Hou

“…Abstract Methyltransferase-like 1 (METTL1)-mediated m7G modification is a common occurrence in various RNA species, including mRNAs, tRNAs, rRNAs, and miRNAs. Recent evidence suggests that this modification is linked to the development of several cancers, making it a promising target for cancer therapy. …”
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miR-370-3p as a Novel Biomarker Promotes Breast Cancer Progression by Targeting FBLN5 by Jiahui Mao, Lingxia Wang, Junying Wu, Yichun Wang, Huiyan Wen, Xueming Zhu, Bo Wang, Huan Yang

“…miRNAs play a crucial part in multiple biological processes of cell proliferation, migration, apoptosis, and chemoresistance. …”
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Comprehensive analysis of ceRNA Networks in UCEC: Prognostic and therapeutic implications. by Li Fan, Mengqiu Lan, Xiaohua Wei, Lili Wei, Liuhong Yang, Liuying Nong, Jiajia Wei, Jingjing Li, Wenjie Huang

“…Differential expression analysis was conducted using the DESeq2 package, identifying differentially expressed lncRNAs, miRNAs, and mRNAs (DElncRNAs, DEmiRNAs, and DEmRNAs). …”
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