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341
miRNA Expression Profile and Effect of Wenxin Granule in Rats with Ligation-Induced Myocardial Infarction
Published 2017-01-01“…This study aims to investigate a comprehensive miRNA expression profile, and the predicted correlation pathways to be targeted by differentially expressed miRNAs in MI, and mechanisms of WXKL from a gene level. …”
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342
gga-miR-6634-5p Affects the proliferation and steroid hormone secretion of chicken (Gallus Gallus) granulosa cells by targeting MMP16
Published 2025-01-01“…MiRNAs are typically reported to play a negative regulatory role in post-transcriptional expression of target genes and are widely involved in a variety of biological processes such as growth, metabolism and reproduction. …”
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343
Salivary Biomarkers: Noninvasive Ways for Diagnosis of Parkinson’s Disease
Published 2023-01-01“…Although salivary flow rate is decreased in PD patients, high levels of heme oxygenase and acetylcholinesterase might be used as noninvasive biomarkers. Salivary miRNAs (miR-153, miR-223, miR-874, and miR-145-3p) are novel diagnostic biomarkers that should be given more attention.…”
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344
Knockdown of Gfi1 increases BMSCs exosomal miR-150-3p to inhibit osteoblast ferroptosis in steroid-induced osteonecrosis of the femoral head through BTRC/Nrf2 axis
Published 2025-02-01“…Additionally, microRNAs (miRNAs) have been identified as regulators of SONFH progression. …”
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345
MicroRNA-451a is a candidate biomarker and therapeutic target for major depressive disorder
Published 2024-02-01“…Background Increasing evidence supports the role of microRNAs (miRNAs) in major depressive disorder (MDD), but the pathophysiological mechanism remains elusive.Aims To explore the mechanism of microRNA-451a (miR-451a) in the pathology and behaviours of depression.Methods Abnormal miRNAs such as miR-451a reported previously in the serum of patients with MDD were screened and then confirmed in a mouse model of depression induced by chronic restraint stress (CRS). …”
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346
Diagnostic Value of Glycosylated Extracellular Vesicle microRNAs in Gastric Cancer
Published 2025-01-01“…The five miRNA pairs could also aid in making treatment decisions. Thus, miRNAs derived from glycosylated exosomes are promising biomarkers for cancer diagnosis.Keywords: biomarker, diagnosis, gastric cancer, extracellular vesicles, microRNAs…”
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347
Impaired hippocampal neurogenesis associated with regulatory ceRNA network in a mouse model of postoperative cognitive dysfunction
Published 2025-02-01“…The identified key regulatory lncRNAs, miRNAs, and drugs provide potential therapeutic targets for POCD prevention and treatment.…”
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348
miRNA-541-5p regulates myocardial ischemia–reperfusion injury by targeting ferroptosis
Published 2025-01-01“…Abstract Background This article aims to use high-throughput sequencing to identify miRNAs associated with ferroptosis in myocardial ischemia–reperfusion injury, select a target miRNA, and investigate its role in H9C2 cells hypoxia-reoxygenation injury. …”
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349
Altered Atlas of Exercise-Responsive MicroRNAs Revealing miR-29a-3p Attacks Armored and Cold Tumors and Boosts Anti-B7-H3 Therapy
Published 2025-01-01“…Increasing evidence has shown that physical exercise remarkably inhibits oncogenesis and progression of numerous cancers and exercise-responsive microRNAs (miRNAs) exert a marked role in exercise-mediated tumor suppression. …”
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350
Noncoding RNA profiling in omentum adipose tissue from obese patients and the identification of novel metabolic biomarkers
Published 2025-02-01“…Noncoding RNAs (ncRNAs), including long noncoding RNAs (lncRNAs), circular RNAs (circRNAs), and microRNAs (miRNAs), play pivotal roles in regulating gene expression. …”
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351
Agathisflavone Inhibits Viability and Modulates the Expression of miR-125b, miR-155, IL-6, and Arginase in Glioblastoma Cells and Microglia/Macrophage Activation
Published 2025-01-01“…Hence, the modulation of miRNAs and inflammatory factors may improve GBM treatments. …”
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352
Reduced Circulating Levels of miR-491-5p and miR-485-3p Are Associated with the Occurrence of Vertebral Fractures in Postmenopausal Women with Osteoporosis
Published 2022-01-01“…This study aims to characterize roles of miRNAs in osteoporosis and subsequent incidence risk of vertebral fractures for postmenopausal women. …”
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353
Dynamic Roles of RNA and RNA Epigenetics in HTLV-1 Biology
Published 2025-01-01“…This review will highlight the dynamic roles of known RNA and post-transcriptional RNA epigenetic modifications within HTLV-1 biology, including viral <i>hbz</i>, long noncoding RNAs, microRNAs (miRNAs), transfer RNAs (tRNAs), R-loops, N6-methyladenosine (m<sup>6</sup>A) modifications, and RNA-based therapeutics and vaccines.…”
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354
Potential Roles of Exosomal lncRNAs in the Intestinal Mucosal Immune Barrier
Published 2021-01-01“…Exosomes are phospholipid bilayer nanovesicles that allow cell-cell communication by secreting physiologically active substances including proteins, lipids, transcription factors, mRNAs, micro-RNAs (miRNAs), and long noncoding RNAs (lncRNAs). Exosomal lncRNAs are involved in immune cell differentiation and the modulation of the immune response. …”
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355
ROLE OF SMALL RNAs IN PLANT DEFENSE AGAINST BIOTIC AND ABIOTIC STRESSES
Published 2014-12-01“…Small RNAs (siRNAs and miRNAs), the pathways of formation and, particularly, their putative functions in plant defense against biotic and abiotic stresses are concisely reviewed. …”
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356
miR-559 Inhibits Proliferation, Autophagy, and Angiogenesis of Hepatocellular Carcinoma Cells by Targeting PARD3
Published 2022-01-01“…Although prevention and treatment of HCC has improved, it still faces poor prognosis and high mortality. miRNAs play a critical role in the tumorigenesis of HCC, but the underlying mechanism has not been well investigated. …”
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357
Genome-Wide Comprehensive Identification and In Silico Characterization of Lectin Receptor-Like Kinase Gene Family in Barley (Hordeum vulgare L.)
Published 2024-01-01“…In addition, 46 putative miRNAs were predicted to target 81 HvlecRLK genes and HvlecRLK13 was the most targeted gene by 8 different miRNAs. …”
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358
MicroRNAs in Neurotoxicity
Published 2012-01-01“…Neurotoxicity can also be brought about by external agents like drugs and alcohol as well as brain injury with miRNAs playing a pivotal role in diseases. It is therefore vital to understand the expression of these microRNAs and their impact on neuronal activities. …”
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359
The Role of Noncoding RNA in Airway Allergic Diseases through Regulation of T Cell Subsets
Published 2022-01-01“…Noncoding RNAs (ncRNAs) are a class of transcribed RNA molecules that cannot be translated into polypeptides and consist of three major categories, microRNAs (miRNAs), long noncoding RNAs (lncRNAs), and circular RNAs (circRNAs). …”
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360
Non-coding RNAs and exosomal ncRNAs in colorectal cancer
Published 2025-02-01“…We focus on microRNAs (miRNAs), long non-coding RNAs (lncRNAs), circular RNAs (circRNAs), and exogenous ncRNAs and their roles in regulating key signaling pathways such as the Wnt/β signaling pathway. β-catenin, PI3K/Akt, and TGF-β. …”
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