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241
Deciphering the Regulatory Network of Some Key Drought-responsive Genes and microRNAs in Canola
Published 2024-02-01“…The hub genes were regulated by vital drought-responsive miRNAs such as miR9558, miR854, miR172, miR834, miR390, and miR167. …”
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242
MicroRNA Profiling in Cartilage Ageing
Published 2017-01-01“…Whilst there is an increasing amount of research on the roles of miRNAs in ageing, there has been scant research on age-related changes in miRNA in a cartilage. …”
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243
Expression of miRNA and Occurrence of Distant Metastases in Patients with Hürthle Cell Carcinoma
Published 2016-01-01“…In the present study, we investigated whether the expression of miRNAs of interest is associated with the occurrence of metastases in patients with HCTC. …”
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244
Exosomes loaded with the anti-cancer molecule mir-1-3p inhibit intrapulmonary colonization and growth of human esophageal squamous carcinoma cells
Published 2024-12-01“…This study will investigate the anti-cancer effects of exosomes loaded with specific anti-cancer microRNAs in vivo and in vitro. Methods Specific miRNAs that were significantly down-regulated in EC tissues were screened using the miRNAs profiling data of human EC tissue samples in TCGA, and the role of their exogenous expression in the proliferation and migration of human EC cell lines, KYSE150 and Eca109, were detected using CCK-8 and Transwell assays. …”
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245
Analysis of whole transcriptome reveals the immune response to porcine reproductive and respiratory syndrome virus infection and tylvalosin tartrate treatment in the porcine alveol...
Published 2025-01-01“…The miRNA-seq revealed that tylvalosin tartrates-enhanced miRNAs might play roles in regulating angiogenesis and innate immune-related functions, and it rescued the expression of three anti-inflammation miRNAs (ssc-miR-30a-5p, ssc-miR-218-5p, and ssc-miR-218) that were downregulated due to PRRSV infection. …”
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246
Prediction of circRNA-miRNA Associations Based on Network Embedding
Published 2021-01-01“…Therefore, predicting associations between circRNAs and miRNAs can promote the understanding of pathogenesis of disease. …”
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247
Determining the Potential Roles of Branched-Chain Amino Acids in the Regulation of Muscle Growth in Common Carp (Cyprinus carpio) Based on Transcriptome and MicroRNA Sequencing
Published 2023-01-01“…Skeletal muscle growth is a complex process; some muscle-specific microRNAs (miRNAs) are involved in the regulation of muscle thickening and muscle mass. …”
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248
Differentially expressed microRNAs in pre-transplant lung biopsies target immune checkpoint proteins and can predict primary graft dysfunction in lung transplantation
Published 2025-02-01“…Specifically, deregulated miRNAs targeted key ICP proteins, including PD-L1, CD40LG, and OX40L. …”
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249
Overexpression of miR-21-5p as a potential pathogenesis marker for ovarian endometriosis
Published 2025-01-01“…Results Our screening qPCR results showed that 9 miRNAs were upregulated (miR-21-5p, miR-200c-3p, miR-19a-3p, miR-203-3p, miR-181b-5p, miR-182-5p, miR-let7a-5p, miR-205-5p, and miR-200b-3p), whereas 2 miRNAs were downregulated (miR-16-5p and miR-222-3p) in ovarian endometriomas compared to eutopic endometrium. …”
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250
An Autocatalytic Platform Combining a Nonlinear Hybridization Chain Reaction and DNAzyme to Detect microRNA
Published 2024-12-01“…MicroRNAs (miRNAs) are small, non-coding RNAs that play pivotal roles in gene regulation; they are increasingly recognized as vital biomarkers for various diseases, notably cancer. …”
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251
A mutation in porcine pre-miR-15b alters the biogenesis of MiR-15b\16-1 cluster and strand selection of MiR-15b.
Published 2017-01-01“…MicroRNAs (miRNAs) are small non-coding RNAs that are involved in translational regulation of the messenger RNA molecules. …”
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252
Advances in Research Related to MicroRNA for Diabetic Retinopathy
Published 2024-01-01“…The aim of this review is to systematically summarize the signaling pathways and molecular mechanisms of miRNAs involved in the occurrence and development of DR, mainly from the pathogenesis of oxidative stress, inflammation, and neovascularization. …”
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253
miRNA-451a and miRNA-125a Expression Levels in Ankylosing Spondylitis: Impact on Disease Diagnosis, Prognosis, and Outcomes
Published 2020-01-01“…Early diagnosis of ankylosing spondylitis (AS) is yet not elucidated, with a potential diagnostic glance of microRNAs (miRNAs). Aim. Study the expression profile of miRNA-451a and miRNA-125a in AS patients and their impact on disease activity and prognosis. …”
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254
Optimizing therapeutic outcomes: preconditioning strategies for MSC-derived extracellular vesicles
Published 2025-02-01“…Additionally, miRNA variability in MSC-EVs presents challenges due to the diverse roles of miRNAs play in regulating gene expression and cell behavior. …”
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255
In vitro high-content screening reveals miR-429 as a protective molecule in photoreceptor degeneration
Published 2025-03-01“…Given their ability to simultaneously modulate multiple molecular pathways, miRNAs represent promising therapeutic tools for disorders with high genetic heterogeneity, such as IRDs. …”
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256
Human Periodontal Ligament Stem Cell-Derived Exosomes Promote Bone Regeneration by Altering MicroRNA Profiles
Published 2020-01-01“…The results showed that seventy-two miRNAs were upregulated and thirty-five miRNAs were downregulated after osteogenic induction. …”
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257
Prediction of Associations between OMIM Diseases and MicroRNAs by Random Walk on OMIM Disease Similarity Network
Published 2013-01-01“…Increasing evidence has revealed that microRNAs (miRNAs) play important roles in the development and progression of human diseases. …”
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258
Competing Endogenous RNA: The Key to Posttranscriptional Regulation
Published 2014-01-01“…Competing endogenous RNA, ceRNA, vie with messenger RNAs (mRNAs) for microRNAs (miRNAs) with shared miRNAs responses elements (MREs) and act as modulator of miRNA by influencing the available level of miRNA. …”
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259
MicroRNA as a Potential Biomarker and Treatment Strategy for Ischemia-Reperfusion Injury
Published 2021-01-01“…With growing evidence that microRNAs (miRNAs) play an important role as posttranscription gene silencing mediators in many I/R injury, in this review, we highlight the microRNAs that are related to I/R injury and their regulatory molecular pathways. …”
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260
Early Biomarkers for Detecting Subclinical Exposure to Fumonisin B1, Deoxynivalenol, and Zearalenone in Broiler Chickens
Published 2024-12-01“…These findings suggest that serum FITC-d, AST, CK, and liver miRNAs could serve as biomarkers for detecting mycotoxin exposure in broiler chickens.…”
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