Comparative miRNAome combined with transcriptome and degradome analysis reveals a novel miRNA-mRNA regulatory network associated with starch metabolism affecting pre-harvest sprout... by Longqing Sun, Ting Zhao, Dandan Qin, Jing Dong, Daorong Zhang, Xifeng Ren

“…In order to further obtain candidate miRNAs, the different datasets of differentially expressed miRNAs were excavated by using differential-expression and time-series analysis. …”
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Integrated microRNA and mRNA signatures associated with overall survival in epithelial ovarian cancer. by Joanna Lopacinska-Jørgensen, Douglas V N P Oliveira, Guy Wayne Novotny, Claus K Høgdall, Estrid V Høgdall

“…However, the role of miRNAs in tumorigenesis is still to be determined, mainly due to the lack of consensus regarding optimal methodologies for identification and validation of miRNAs and their targets. …”
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In silico identification of chilli genome encoded MicroRNAs targeting the 16S rRNA and secA genes of “Candidatus phytoplasma trifolii” by Vineeta Pandey, Aarshi Srivastava, Ramwant Gupta, Haitham E. M. Zaki, Haitham E. M. Zaki, Muhammad Shafiq Shahid, Rajarshi K. Gaur

“…P. trifolii”) through plant miRNA prediction algorithms. Mature chilli miRNAs (CA-miRNAs) were collected and used to hybridise the 16S rRNA and secA genes. …”
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Elevated and Correlated Expressions of miR-24, miR-30d, miR-146a, and SFRP-4 in Human Abdominal Adipose Tissue Play a Role in Adiposity and Insulin Resistance by Yury O. Nunez Lopez, Gabriella Garufi, Magdalena Pasarica, Attila A. Seyhan

“…We explored the relationships among microRNAs (miRNAs) and SFRP4, as they relate to adipose tissue functions including lipolysis, glucose and glycerol turnover, and insulin sensitivity. …”
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Elucidating the molecular basis of salt tolerance in potatoes through miRNA expression and phenotypic analysis by Caicai Lin, Shuangshuang Zheng, Kui Liu, Ru Yu, Peiyan Guan, Baigeng Hu, Lingling Jiang, Mengyu Su, Guodong Hu, Qingshuai Chen, Xia Zhang

“…Transcriptome analysis of the highly tolerant variety Z1076-1 identified 68 differentially expressed miRNAs (DE miRNAs). qRT-PCR validation for eight randomly selected DE miRNAs confirmed consistent expression trends with transcriptome data. …”
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Extracellular vesicular microRNAs and cardiac hypertrophy by Hai Hu, Hai Hu, Xiulian Wang, Hui Yu, Hui Yu, Zhanli Wang

“…Finally, the potential role of EV-derived miRNAs as targets in the diagnosis and treatment of cardiac hypertrophy will be discussed.…”
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Comprehensive analysis of mRNA and miRNA differential expression profiles in the hypothalamus-pituitary-gonadal axis in laying and broodiness period of Wanxi white geese by Xinwei Tong, Xiaojin Li, Yuhua Wang, Fei Xie, Ruidong Li, Man Ren, Qianqian Hu, Shenghe Li

“…In addition, 22 potential hub miRNAs were screened. Dual luciferase reporter assays confirmed the targeting relationship between miR-144-y and DIO3. …”
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MicroRNA Profiling: From Dark Matter to White Matter, or Identifying New Players in Neurobiology by Anna M. Krichevsky

“…Contemporary biology has been revolutionized by a recently discovered class of small regulatory RNA molecules, microRNAs (miRNAs). Missed by researchers for decades due to their tiny size, usually mapping to non-protein-coding regions of genomes, miRNAs and miRNA-mediated regulatory networks have been the “dark matter” of molecular biology. …”
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Impact of periodontal microRNAs associated with alveolar bone remodeling during orthodontic tooth movement: a randomized clinical trial by Alessandro Polizzi, Angela Alibrandi, Antonino Lo Giudice, Alfio Distefano, Laura Orlando, Amer M. Analazi, Giuseppe Pizzo, Giovanni Li Volti, Gaetano Isola

“…Abstract Background Micro-RNAs (miRNAs) have been reported to play an important role during orthodontic tooth movement (OTM) through the regulation of periodontal soft and hard tissue homeostasis and functions. …”
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RNA-Sequence Reveals the Regulatory Mechanism of miR-149 on Osteoblast Skeleton under Mechanical Tension by Yifan Wang, Guanyin Zhu, Fang Pei, Yigan Wang, Jun Liu, Caixia Lu, Zhihe Zhao

“…Based on RNA-sequencing (RNA-seq), the regulation of miRNAs differentially expressed in dental, periodontal, and alveolar bone tissue of orthodontic tree shrews on osteoblast skeleton under tension was investigated. …”
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Function of Dicer with regard to Energy Homeostasis Regulation, Structural Modification, and Cellular Distribution by Xiaohui Tong, Nianjun Yu, Rongchun Han, Tongsheng Wang

“…Through miRNAs, Dicer regulates the hypothalamic melanocortin-4 system and central autophagy promoting energy expenditure. …”
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hsa-miR-548d-3p: a potential microRNA to target nucleocapsid and/or capsid genes in multiple members of the Flaviviridae family by H. W. Cayatineto, S. T. Hakim

“…These viruses cause diseases ranging from mild to severe and are considered important human pathogens. MicroRNAs (miRNAs) are non-coding molecules involved in growth, development, cell proliferation, protein synthesis, apoptosis, and pathogenesis. …”
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MicroRNAs in pancreatic cancer drug resistance: mechanisms and therapeutic potential by Fangying Dong, Jing Zhou, Yijie Wu, Zhaofeng Gao, Weiwei Li, Zhengwei Song

“…Pancreatic cancer (PC) remains one of the most lethal malignancies, primarily due to its intrinsic resistance to conventional therapies. MicroRNAs (miRNAs), key regulators of gene expression, have been identified as crucial modulators of drug resistance mechanisms in this cancer type. …”
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Let-7b-5p sensitizes breast cancer cells to doxorubicin through Aurora Kinase B. by Murat Kaya, Asmaa Abuaisha, Ilknur Suer, Selman Emiroglu, Semen Önder, Evren Onay Ucar, Mustafa Nuri Yenerel, Sukru Palanduz, Kivanc Cefle, Sukru Ozturk, Zeyneb Kurt

“…MicroRNAs (miRNAs) are small, non-coding RNAs that regulate the expression level of the target genes in the cell. …”
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The miR-23a/27a/24 − 2 cluster drives immune evasion and resistance to PD-1/PD-L1 blockade in non-small cell lung cancer by Hao Luo, Bin Hu, Xiang-Rong Gu, Jing Chen, Xiao-Qing Fan, Wei Zhang, Ren-Tao Wang, Xian-Dong He, Wei Guo, Nan Dai, Dan Jian, Qing Li, Cheng-Xiong Xu, Hua Jin

“…In summary, we elucidate the mechanism by which the miR-23a/27a/24 − 2 cluster miRNAs maintain their own expression and the molecular mechanism by which the miR-23a/27a/24 − 2 cluster miRNAs promote tumor immune evasion and PD-1/PD-L1 blockade resistance. …”
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Analysis of Circulating Plasma MicroRNA Profile in Low-Grade and High-Grade Glioma – A Cross-Sectional Study [version 1; peer review: 2 approved, 1 approved with reservations, 1 no... by Sekar Safitri, Rachmat Andi Hartanto, Rusdy Ghazali Malueka, Bo Sun, Ery Kus Dwianingsih, Kusumo Dananjoyo, Ahmad Asmedi, Endro Basuki, Christina Megawimanti Sianipar, Yeshua Putra Krisnugraha

“…Circulating microRNAs (miRNAs) are considered as promising biomarkers for glioma due to their sensitivity, specificity, and non-invasive properties. …”
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What Is in the Field for Genetics and Epigenetics of Diabetic Neuropathy: The Role of MicroRNAs by V. Spallone, C. Ciccacci, A. Latini, P. Borgiani

“…After a brief summary of recent studies on the genetics of diabetic neuropathy, the current review focused mainly on microRNAs (miRNAs), including the authors’ results in this field. …”
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An Ex Vivo Study on Release, Uptake, and miRNA Profile of Exosomes in Rat Lens by Junfang Zhang, Jiawei Luo, Guowei Zhang, Bai Qin, Xiumei Ren, Huaijin Guan

“…LECs released numerous exosomes into the medium through the capsule, which contained abundant miRNAs. The most abundant miRNAs included miR-184, let-7c-5p, let-7a-5p, let-7b-5p, let-7f-5p, miR-125a-5p, miR-204-5p, miR-125b-5p, miR-1b, and miR-23a-3p. …”
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miRNA-Disease Association Prediction with Collaborative Matrix Factorization by Zhen Shen, You-Hua Zhang, Kyungsook Han, Asoke K. Nandi, Barry Honig, De-Shuang Huang

“…As one of the factors in the noncoding RNA family, microRNAs (miRNAs) are involved in the development and progression of various complex diseases. …”
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The Multifaceted Role of Extracellular Vesicles in Glioblastoma: microRNA Nanocarriers for Disease Progression and Gene Therapy by Natalia Simionescu, Radu Zonda, Anca Roxana Petrovici, Adriana Georgescu

“…Glioblastoma (GB) is the most aggressive form of brain cancer in adults, characterized by poor survival rates and lack of effective therapies. MicroRNAs (miRNAs) are small, non-coding RNAs that regulate gene expression post-transcriptionally through specific pairing with target messenger RNAs (mRNAs). …”
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