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181
Increased expression of plasma mir-9-3p and let-7b-3p in methamphetamine use disorder and its clinical significance
Published 2024-12-01“…This study endeavors to elucidate the alterations in expression changes of miRNAs in the plasma of methamphetamine use disorder and elucidate the alterations in miRNA expression in the plasma of individuals with methamphetamine use disorder and investigate the relationship between these differentially expressed miRNAs and the disorder itself, cravings for methamphetamine, and associated mental disorders. …”
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182
Reconstruction and computational analysis of the microRNA regulation gene network in wheat drought response mechanisms
Published 2025-01-01“…The key network components regulated by miRNAs are the MYBa and WRKY41 family transcription factors, heat-shock protein HSP90, and the RPM1 protein. …”
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183
Whole transcriptome analysis and construction of gene regulatory networks of granulosa cells from patients with polycystic ovary syndrome (PCOS)
Published 2025-01-01“…Among the ncRNAs, there were 2047 lncRNAs, 892 circRNAs, and 1389 miRNAs. Based on the condition |log2(fold_change) |≥ 1 and a P-value of ≤ 0.05, we obtained 705 differentially expressed genes (DEGs), 204 differentially expressed lncRNAs, 111 differentially expressed circRNAs, and 88 differentially expressed miRNAs. …”
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184
Computational identification and experimental validation of novel Saccharum officinarum microRNAs along with their targets through RT-PCR approach
Published 2025-12-01“…Various metabolic and cell signaling processes impact the functions of sugarcane plant cells. MicroRNAs (miRNAs) play critical regulatory roles in enhancing yield and providing protection against various stressors. …”
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185
MicroRNA functions in osteogenic differentiation of periodontal ligament stem cells: a scoping review
Published 2025-01-01“…In conclusion, Exosome-derived miRNAs play a key role in PDLSCs osteogenic differentiation during tissue regeneration. …”
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186
Cell-Free miR-27a, a Potential Diagnostic and Prognostic Biomarker for Gastric Cancer
Published 2015-09-01“…MicroRNAs (miRNAs) have been demonstrated to play an important role in carcinogenesis. …”
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187
Hairpin in a haystack: In silico identification and characterization of plant-conserved microRNA in Rafflesiaceae
Published 2025-01-01“…In this study, we use homology-based in silico approaches to characterize micro-RNAs (miRNAs) expressed by Sapria himalayana and Rafflesia cantleyi from published omics data. …”
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188
Enhancing Venous Thromboembolism Risk Prediction through Novel Biomarkers and Inflammatory Indicators
Published 2024-12-01“…CONCLUSION: The study highlights the importance of novel biomarkers such as thrombin generation time, factor VIII levels, circulating miRNAs, and inflammatory markers in assessing VTE risk. …”
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189
Expanding the miRNA Transcriptome of Human Kidney and Renal Cell Carcinoma
Published 2018-01-01“…We find that these novel kidney miRNAs are also expressed in renal cancer cell lines. …”
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190
The Potential Importance of MicroRNAs as Novel Indicators How to Manage Patients with Juvenile Idiopathic Arthritis More Effectively
Published 2021-01-01“…Small, noncoding sequences of ribonucleic acid called microRNAs (miRNAs, miR) are functioning as posttranscriptional regulators of gene expression. …”
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191
Exosome-Derived microRNA: Potential Target for Diagnosis and Treatment of Sepsis
Published 2024-01-01“…Exosome-derived microRNAs (miRNAs) are emerging as pivotal players in the pathophysiology of sepsis, representing a new frontier in both the diagnosis and treatment of this complex condition. …”
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192
microRNAs as a New Mechanism Regulating Adipose Tissue Inflammation in Obesity and as a Novel Therapeutic Strategy in the Metabolic Syndrome
Published 2014-01-01“…This review will focus on the implication of miRNAs in white AT inflammation in obesity, and will also highlight the potential of miRNAs as targets for therapeutic intervention in MS as well as the challenges lying in miRNA-targeting therapeutics.…”
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193
The Potential of MicroRNAs as Novel Biomarkers for Transplant Rejection
Published 2017-01-01“…The control of gene expression by microRNAs (miRNAs, miR) influences many cellular functions, including cellular differentiation, cell proliferation, cell development, and functional regulation of the immune system. …”
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194
miR-155: An Important Role in Inflammation Response
Published 2022-01-01“…MicroRNAs (miRNAs) are a class of small, mature, noncoding RNA that lead to posttranscriptional gene silencing to regulate gene expression. miRNAs are instrumental in biological processes such as cell development, cell differentiation, cell proliferation, and cell apoptosis. …”
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195
Hsa-miR-532-3p protects human decidual mesenchymal stem cells from oxidative stress in recurrent spontaneous abortion via targeting KEAP1
Published 2025-03-01“…However, the miRNAs involved in regulating oxidative stress in hDMSCs remain unclear. …”
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196
miRNA-375 a Sensor of Glucotoxicity Is Altered in the Serum of Children with Newly Diagnosed Type 1 Diabetes
Published 2016-01-01“…Background. The use of miRNAs as biomarkers for Type 1 Diabetes (T1D) risk is attractive as T1D is usually diagnosed in front of acute symptoms. …”
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197
Mechanisms of miRNA-Mediated Gene Regulation from Common Downregulation to mRNA-Specific Upregulation
Published 2014-01-01“…Discovered in 1993, micoRNAs (miRNAs) are now recognized as one of the major regulatory gene families in eukaryotes. …”
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198
MicroRNAs as Prognostic Biomarkers for Atrial Fibrillation Recurrence After Catheter Ablation: Current Evidence and Future Directions
Published 2024-12-01“…This review presents the existing evidence on the prognostic role of microRNAs (miRNAs) in the prediction of AF recurrence after catheter ablation. …”
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199
Analysis of Exosomal miRNA and Hepatic mRNA Expression in the Dysregulation of Insulin Action in Perimenopausal Mice
Published 2025-01-01“…Conclusion: The perimenopausal period acts as a potential factor in introducing insulin resistance as evidenced by impaired insulin action and altered expression profiles of exosomal miRNAs and hepatic genes. The present study contributes to the understanding that abnormal cargos carried by plasma exosomes, such as miRNAs, may be related to altered expression of the corresponding genes in the liver and abnormal insulin response.…”
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200
Investigating the miRNA-mRNA interactome of human trabecular meshwork cells treated with TGF-β1 provides insights into the pathogenesis of pseudoexfoliation glaucoma.
Published 2025-01-01“…Pseudoexfoliation glaucoma is a severe form of secondary open angle glaucoma and is associated with activation of the TGF-β pathway by TGF-β1. MicroRNAs (miRNAs) are small non-coding RNA species that are involved in regulation of mRNA expression and translation. …”
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