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Risk of hereditary spherocytosis misdiagnosis due to limited effective diagnostic methods
Published 2025-02-01“…The percentage of spherocytes was scored from peripheral blood smear observation; the percentage of decreased mean fluorescent intensity from Eosin-5'-maleimide binding assay was used to determine red cell membrane protein deficiency, and hereditary spherocytosis was finally confirmed by gene sequencing as a gold standard. …”
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82
Identification of CTL Epitopes on Efflux Pumps of the ATP-Binding Cassette and the Major Facilitator Superfamily of Mycobacterium tuberculosis
Published 2021-01-01“…In this study, we identified cytotoxic T lymphocyte epitopes on drug resistance-associated membrane protein efflux pumps of MTB, the ATP-binding cassette and the major facilitator superfamilies. …”
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83
The impact of intermittent preventive treatment in school aged children with dihydroartemisinin piperaquine and artesunate amodiaquine on IgG response against six blood stage Plasm...
Published 2025-01-01“…This study compared IgG reactivity against GLURP-R2, MSP1, MSP3, and CIDR domains (CIDRa1.1, CIDRa1.4, and CIDRa1.5) of Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP-1) in intervention and control groups using enzyme linked immunosorbent assay (ELISA) technique. …”
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84
Immunolocalization of SP22 (Park7) on the human sperm membrane is indicative of live birth
Published 2025-01-01“…More than twenty years have passed since we discovered a novel sperm membrane protein (SP22) derived from the Park7 gene that is highly correlated with the fertility of rat sperm exposed to epididymal toxicants. …”
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85
Identification and Characterization of the <i>LecRLKs</i> Gene Family in Maize, and Its Role Under Biotic and Abiotic Stress
Published 2024-12-01“…Plant lectin receptor-like kinases (LecRLKs) are plant membrane protein receptor kinases. Lectin-like receptor kinases play a crucial role in regulating plant growth, development, and responses to environmental stimuli. …”
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86
Development of IgY-Based Sandwich ELISA as a Robust Tool for Rapid Detection and Discrimination of Toxigenic Vibrio cholerae
Published 2018-01-01“…This study aimed to introduce two sensitive sandwich ELISAs based on avian antibodies (IgY) targeting outer membrane protein W (OmpW) and cytotoxin B (CtxB) antigens of V. cholerae. …”
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87
Acquisition of Fc-afucosylation of PfEMP1-specific IgG is age-dependent and associated with clinical protection against malaria
Published 2025-01-01“…Abstract Protective immunity to malaria depends on acquisition of parasite-specific antibodies, with Plasmodium falciparum erythrocyte membrane protein 1 (PfEMP1) being one of the most important target antigens. …”
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88
Neuromyelitis optica spectrum disorder: epidemiology, pathogenesis, diagnosis, treatment, and prognosis
Published 2021-03-01“…The main pathogenetic mechanism of NMOSD is the interaction of aquaporin-4 (AQP4), an integral astrocyte plasma membrane protein, and antibodies against aquaporin-4 (AQP4-IgG). …”
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89
A framework for the simulation of individual glycan coordinates to analyze spatial relationships within the glycocalyx
Published 2025-01-01“…It plays crucial roles in various cellular processes in health and disease, such as cancer immune evasion, cancer immune therapy, blastocyst implantation, and functional attenuation of membrane protein diffusion. In addition, alterations in glycocalyx structure may play an important role in ocular surface diseases, e.g., dry eye disease. …”
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90
Vaccinomics Approach for Designing Potential Peptide Vaccine by Targeting Shigella spp. Serine Protease Autotransporter Subfamily Protein SigA
Published 2017-01-01“…Casein-degrading serine protease autotransporter of enterobacteriaceae (SPATE) subfamily protein SigA, an outer membrane protein, exerts both cytopathic and enterotoxic effects especially cytopathic to human epithelial cell type-2 (HEp-2) and is shown to be highly immunogenic. …”
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91
Effects of orally exposed SiO2 nanoparticles on lipid profiles in gut-liver axis of mice
Published 2025-01-01“…However, lysosomal-associated membrane protein 2 (Lamp2) showed different trend, that it was significantly increased in intestines but decreased in livers. …”
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92
Lacticaseibacillus rhamnosus Fmb14 ameliorates hyperuricemia-induced hepatocyte pyroptosis via NLRP3 inflammasome cascade inhibition
Published 2024-07-01“…L. rhamnosus Fmb14 administration restored mitochondrial inner membrane protein (MPV17) and connexin 43 from 2.83 and 0.73 to 0.80 and 0.98 respectively in PDIH mice, indicating that dysbiosis of mitochondrial membrane potential was restored in liver. …”
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93
Study on Management of Blood Transfusion Therapy in Patients with Hereditary Spherocytosis
Published 2022-01-01“…Based on the sequencing results, the type of mutated membrane protein in each proband was analyzed using the eosin-5′-maleimide (EMA) binding test and sodium dodecyl sulfate polyacrylamide gel electrophoresis (SDS-PAGE). …”
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94
O Serogroup-Specific Touchdown-Multiplex Polymerase Chain Reaction for Detection and Identification of Vibrio cholerae O1, O139, and Non-O1/Non-O139
Published 2014-01-01“…A panel of molecular marker-based TMPCR method generates reproducible profiles of V. cholerae-specific (588 bp) amplicons derived from ompW gene encoding the outer membrane protein and serogroup-specific amplicons, 364 bp for the O1 and 256 bp for the O139, authentically copied from rfb genes responsible for the lipopolysaccharide biosynthesis. …”
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95
Network pharmacology and in silico investigation into the therapeutic potential of phytoconstituents of Peucedanum ostruthium as anti-tubercular agents
Published 2025-03-01“…In addition, the docking studies demonstrated that kampeferol-3-O-rutinoside exhibits stronger binding affinities to the Mycobacterial membrane protein Large 3 (MmpL3). This study presents compelling evidence that P. ostruthium may be effectively used to target TB after experimental validation. …”
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96
Characterizations of cytokines and viral genomes in serum of patients with Dabie bandavirus infection
Published 2025-01-01“…The ratio of dN/dS in the membrane protein was the highest. SZ03-TXF was a recombinant strain with the location of possible breakpoints at nucleotides 795 and 1,432 in the CDS region of the L segment.ConclusionA recombination event was identified in SZ03-TXF strain. …”
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97
Circulating CD3+HLA-DR+ Extracellular Vesicles as a Marker for Th1/Tc1-Type Immune Responses
Published 2019-01-01“…To establish T cell subset-specific biomarkers, we performed proteomic analysis with Th1- and Th2-derived EVs and identified HLA-DR as a Th1-dominated EV membrane protein. We designed a measurement system for CD3+CD4+, CD3+CD8+, and CD3+HLA-DR+ EVs to specifically determine EV subpopulations derived from CD4+, CD8+, and Th1-type T cells, respectively. …”
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98
Establishment of a rapid method for the detection of Brucella canis based on recombinase-mediated thermostable nucleic acid amplification technology
Published 2025-01-01“…ObjectiveTo establish a rapid detection method for canine brucellosis using recombinase-aided amplification (RAA) technology.MethodsThe outer membrane protein 25 gene fragment (Omp25) of Brucella canis was targeted. …”
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99
Characterization of chemosensory genes in the subterranean pest Gryllotalpa Orientalis based on genome assembly and transcriptome comparison
Published 2025-01-01“…This sensory process is governed by diverse gene families, including odorant-binding proteins (OBPs), olfactory receptors (ORs), ionotropic receptors (IRs), chemosensory proteins (CSPs), gustatory receptors (GRs), and sensory neuron membrane proteins (SNMPs). The oriental mole cricket (Gryllotalpa orientalis Burmeister), an invasive pest with an underground, phyllophagous lifestyle, causes substantial crop damage. …”
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100
SLC25A38 is required for mitochondrial pyridoxal 5’-phosphate (PLP) accumulation
Published 2025-01-01“…In this study, we used a genome-wide CRISPR interference screen in erythroleukemia cells and organellar metabolomics to identify the mitochondrial inner membrane protein SLC25A38 as a regulator of mitochondrial pyridoxal 5’-phosphate. …”
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