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41
Ion channel classification through machine learning and protein language model embeddings
Published 2024-11-01Subjects: Get full text
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42
Structure of an ex vivoDrosophila TOM complex determined by single-particle cryoEM
Published 2025-01-01Subjects: Get full text
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43
Specific Immune Responses and Oncolytic Effects Induced by EBV LMP2A-Armed Modified Ankara-Vaccinia Virus Vectored Vaccines in Nasopharyngeal Cancer
Published 2025-01-01Subjects: “…Epstein-Barr virus latent membrane protein 2A…”
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44
A guide to selecting high-performing antibodies for VAPB (UniProt ID: O95292) for use in western blot, immunoprecipitation, and immunofluorescence [version 1; peer review: 3 approv...
Published 2024-12-01Subjects: “…Vesicle-associated membrane protein-associated protein B/C…”
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45
Escherichia coli O127 group 4 capsule proteins assemble at the outer membrane.
Published 2021-01-01“…We have developed an expression system for the large-scale production of the outer membrane protein GfcD. Contrary to annotations, we find that GfcD is a non-acylated integral membrane protein. …”
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46
Machine learning models for predicting interaction affinity energy between human serum proteins and hemodialysis membrane materials
Published 2025-01-01“…Affinity energy, defined as the strength of interaction between membranes and human serum proteins, plays a crucial role in assessing membrane-protein interactions. These interactions may trigger adverse reactions, potentially harmful to patients. …”
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47
Fragment optimized chalcone derivatives targeting OmpA protein as a therapeutic approach against multidrug resistant Acinetobacter baumannii
Published 2025-01-01“…Abstract Acinetobacter baumannii is a notorious pathogen associated with life-threatening infections, with its outer membrane protein A (OmpA) being a key contributor to its pathogenicity by targeting epithelial cell apoptosis. …”
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48
Development of an sRNA-mediated conditional knockdown system for Chlamydia trachomatis
Published 2025-02-01“…To test for polar effects, we separately targeted the inclusion membrane proteins IncE and IncG, which are expressed from the incDEFG operon. …”
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49
UPR-Mediated Membrane Biogenesis in B Cells
Published 2012-01-01“…In activated B cells, the demand for membrane protein and lipid components leads to activation of the UPR transcriptional activator XBP1(S) which, in turn, initiates a cascade of biochemical events that enhance supplies of phospholipid precursors and build machinery for the synthesis, maturation, and transport of secretory proteins. …”
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50
Diffusion-driven self-assembly of emerin nanodomains at the nuclear envelope
Published 2025-01-01“…Emerin, a nuclear membrane protein with important biological roles in mechanotransduction and nuclear shape adaptation, self-assembles into nanometer-size domains at the inner nuclear membrane. …”
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51
Tissue Factor Structure and Function
Published 2012-01-01“…Tissue factor (TF) is an integral membrane protein that is essential to life. It is a component of the factor VIIa-TF complex enzyme and plays a primary role in both normal hemostasis and thrombosis. …”
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52
Updated review on diagnosis of Helicobacter pylori
Published 2024-10-01“…The main themes include invasive and noninvasive diagnostic methods of H. pylori, newer methods, such as a panel of ten H. pylori specific antibodies test, testing for H. pylori using gastric fluid and outer membrane protein-cell receptor reactions diagnostic methods, and serological and pepsinogen tests. …”
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53
Adaptive Genetic Traits in Human Populations: Evolutionary Responses to Malaria
Published 2025-01-01“…Notable adaptations include hemoglobinopathies (sickle cell trait, thalassemias, hemoglobin C), enzyme disorders (G6PD deficiency, pyruvate kinase deficiency), and membrane protein variations (Duffy antigen negativity, hereditary ovalocytosis). …”
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54
Recycling of endocytic BDNF through extracellular vesicles in astrocytes
Published 2025-01-01“…Downregulation of vesicle-associated membrane protein 3 (Vamp3) led to an increase in the colocalization of endosomal BDNF and CD63 but a decrease in extracellular vesicle release, suggesting the necessity of Vamp3-dependent signaling for EV-mediated BDNF secretion. …”
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55
Protein-Mediated Interactions of Pancreatic Islet Cells
Published 2013-01-01“…Among these, several mechanisms depend on different families of integral membrane proteins, which ensure direct (cadherins, N-CAM, occludin, and claudins) and paracrine communications (pannexins) between beta cells, and between these cells and the other islet cell types. …”
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56
Drug Resistance Mechanism of Enterobacteriaceae with Decreased Antibiotic Sensitivity
Published 2022-01-01“…Plasmid-mediated deletion of IMP-1 metallo-β-lactamase binding outer membrane protein is one of the main reasons for the decrease of antibiotic sensitivity.…”
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57
Soluble Urokinase Receptor and the Kidney Response in Diabetes Mellitus
Published 2017-01-01“…Recently, podocyte membrane protein urokinase receptor (uPAR) and its circulating form (suPAR) are found to be significantly induced in glomeruli and sera of DN patients, respectively, and elevated suPAR levels predicted diabetic kidney disease years before the occurrence of microalbuminuria. …”
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58
Irisin a Novel Metabolic Biomarker: Present Knowledge and Future Directions
Published 2018-01-01“…It is the product of type I membrane protein cleavage encoded by the fibronectin type III domain containing 5 (FNDC5) gene. …”
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59
Mining the Virgin Land of Neurotoxicology: A Novel Paradigm of Neurotoxic Peptides Action on Glycosylated Voltage-Gated Sodium Channels
Published 2012-01-01“…Voltage-gated sodium channels (VGSCs) are important membrane protein carrying on the molecular basis for action potentials (AP) in neuronal firings. …”
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60
The Effect of Highly Hydroxylated Fullerenol C60(OH)36 on Human Erythrocyte Membrane Organization
Published 2015-01-01“…This confirms that fullerenol interacts with erythrocyte membrane proteins via available protein –SH groups.…”
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