Druggability and molecular docking of essential secondary metabolites from Azadirachta indica leaf against angiotensin converting enzyme-2: Covid-19 in focus by Paul Chijioke Ozioko, Ukamaka Owohetete, Daniel Danladi Gaiya

“…Of the 5 FDAapproved medications for the treatment of COVID-19 under investigation, only paritaprevir was able to dock (representing 20%); while 6 out of the 12 compounds from A. indica were able to dock perfectly (representing 50%). …”
Get full text

Diabetes self-management education interventions in the WHO African Region: A scoping review. by Emmanuel Kumah, Godfred Otchere, Samuel Egyakwa Ankomah, Adam Fusheini, Collins Kokuro, Kofi Aduo-Adjei, Joseph A Amankwah

“…While the majority yielded significant positive results on HbA1c, diabetes knowledge, blood pressure, blood sugar and foot care practices; few demonstrated positive outcomes on self-efficacy, BMI, physical activity; self-monitoring of blood glucose, medication adherence, smoking and alcohol consumption.…”
Get full text

New era, new GOALs: cardiovascular screening and lipid management in cystic fibrosis by Katherine A. Despotes, Agathe S. Ceppe, Jennifer L. Goralski, Scott H. Donaldson

“…In the past year, 29% of adult providers prescribed lipid-lowering therapy, 54% started anti-hypertensive medications, and 48% initiated ischemic cardiac evaluations for pwCF. …”
Get full text

Acute dental pain and the different management methods among adults in Taif, Saudi Arabia: A cross-sectional study by Bandar S. Shukr, Ayman Mandorah, Faisal K. Altalhi, Yousef A. Alqurashi, Hassan T. Shawli, Ali A. Alqarni, Mohammed A. Alzubaidi

“…Conclusion: The prevalence of acute dental pain and self-medication practices was notably high among the study population. …”
Get full text

Environmental maternal exposures and the risk of premature birth and intrauterine growth restriction: The Generation Gemelli study protocol of newborn exposome. by Leonardo Villani, Angelo Maria Pezzullo, Roberta Pastorino, Alessandra Maio, Francesca Stollagli, Chiara Tirone, Marta Barba, Angela Maria Cozzolino, Denise Pires Marafon, Martina Porcelli, Annamaria Sbordone, Maria Letizia Patti, Anthea Bottoni, Angela Paladini, Simona Fattore, Domenico Marco Romeo, Ornella Parolini, Wanda Lattanzi, Guido Rindi, Luca Tamagnone, Marco Marazza, Maurizio Genuardi, Elisabetta Tabolacci, Eugenio Maria Mercuri, Antonio Chiaretti, Tina Pasciuto, Maurizio Sanguinetti, Vincenzo Valentini, Giovanni Scambia, Walter Ricciardi, Giovanni Vento, Antonio Lanzone, Stefania Boccia

“…We will conduct clinical follow-up assessments in both cases and controls at months 12 and 24 and we will collect anthropometric data, feeding types with particular reference to breastfeeding and its duration, pediatric emergency room visits, hospitalizations, medication usage, known allergies, and neuropsychological development.…”
Get full text

Developing a patient-centered measure to assess food-related and nutrition-related quality of life in patients with cancer by Seth Berkowitz, Mackenzie Kemp, Sara Beachy, Karla Martin, Brooke Worster, Richard W Hass, Iyaniwura Olarewaju, Kristin L Rising

“…Multiple linear regression found that receipt of medically tailored meals and treatment-related symptoms were related to FN-QoL when adjusting for all other variables.Conclusion Results suggest validity and potential utility of the FN-QoL measure to assess impact of food and nutrition interventions on quality of life among patients with cancer. …”
Get full text

Systematic review of spontaneous reports of myocarditis and pericarditis in transplant recipients and immunocompromised patients following COVID-19 mRNA vaccination by Saad Shakir, Samantha Lane, Alison Yeomans

“…Reports with comorbidities or concurrent medication indicative of transplantation, HIV infection or cancer (‘immunocompromised’ population) were compared with each overall database population.Data extraction and synthesis Two researchers extracted data. …”
Get full text

Long-term prognostic impact of glucagon-like peptide-1 receptor agonist before ST-segment elevation myocardial infarction in patients with type 2 diabetes: a nationwide cohort stud... by Jasmine Melissa Madsen, Alexander Krüger Kjaer, Jacob Thomsen Lønborg, Lars Køber, Charlotte Glinge, Reza Jabbari, Thomas Engstrøm

“…Type 2 diabetes was defined by prior hospital admission with type 2 diabetes or anti-diabetic prescriptions within one year before STEMI. Dispensed GLP-1RA medication was retrieved within one year before STEMI. …”
Get full text

Construction of a predictive model for the risk of aspiration in enteral nutrition patients in ICU by CHEN Yue, ZHANG Hui, GUAN Chun, HU Fasheng

“…The independent risk factors were ranked in order of importance from highest to lowest as number of days of placement [OR=1.038, 95%CI(1.024, 1.052)], body position [OR=3.879, 95%CI(2.104, 7.152)], duration of daily enteral nutrition [OR=1.035, 95%CI(1.004, 1.067)], APACHE II score [OR=1.063, 95%CI(1.032, 1.095)], use of sedative and analgesic medication [OR=4.054, 95%CI(1.804, 9.108)], partial pressure of oxygen [OR=0.985, 95%CI(0.974, 0.997)]. …”
Get full text

Association of dysautonomia and different risk factors in patients with Guillain-Barré syndrome in a tertiary hospital in the Philippines by Gerald T. Pagaling, Lowrence Precious C. Dichoso, Nikolai Gil D. Reyes, Mario B. Prado

“…The protective mechanism of premorbid hypertension could be attributed to the prior intake of antihypertensive medications, which mitigate cardiosympathetic fluctuations, while the protective effect of alcoholism needs to be further studied. …”
Get full text

Effect of potent nucleos(t)ide analog on alpha fetoprotein changes and occurrence of hepatocellular carcinoma in patients with chronic hepatitis B by Qianqian Ma, Junzhao Ye, Ling Luo, Yanhong Sun, Wei Wang, Shiting Feng, Bing Liao, Bihui Zhong

“…However, it is unclear whether different antiviral medications have varying effects on AFP levels. The purpose of this study was to evaluate this issue in those treated with entecavir (ETV) versus tenofovir disoproxil fumarate (TDF). …”
Get full text

Short-term and long-term prognoses in AChR-Ab positive very-late-onset myasthenia gravis patients by Nairong Xie, Qing Liu, Qi Wen, Yaye Wang, Haoran Liu, Yuting Jiang, Yan Lu, Li Di, Min Wang, Wenjia Zhu, Xinmei Wen, Xuxiang Zhang, Xin-Ming Shen, Yuwei Da

“…Conclusion: This study demonstrated that AChR-ab positive VLOMG patients have a favorable prognosis and responded well to medication, with age and comorbidities showing no significant impact.…”
Get full text

Sound-Induced Flash Illusions Support Cortex Hyperexcitability in Fibromyalgia by Vincenzo Di Stefano, Salvatore Iacono, Andrea Gagliardo, Bruna Maggio, Giuliana Guggino, Massimo Gangitano, Roberto Monastero, Vito Renato Maggio, Nadia Bolognini, Filippo Brighina

“…., FM, FM with migraine, and HCs) using repeated-measures analysis of variance. Medication history was recorded along with the administration of Fibromyalgia Impact Questionnaire and Hospital Anxiety and Depression scales. …”
Get full text

Research status of east Asian traditional medicine treatment for chronic cough: A scoping review. by Boram Lee, Chan-Young Kwon, Ye Ji Kim, Jae Hyun Kim, Kwan-Il Kim, Beom-Joon Lee, Jun-Hwan Lee

“…EATM was conducted for a mean of 19.1 days, and herbal medicine was the most common (80.6%). Conventional medication was frequently used as a control (81.2%). …”
Get full text

Real-Life State of Anti-Hepatitis B Virus Drug Choice in Child-Bearing Age Male Patients and Effect on Fertility and Fetal Safety by Zhao X. Hu, Yi N. Ye, Wei G. Wu, Xu J. Liang, Qi W. Wu, Ao Zhang, Xing R. Zheng, Zhi L. Gao, Liang Peng, Chan Xie

“…We collected data including medication type, fertility, and birth defects. Moreover, a survey of the knowledge of antiviral nucleoside analogs safety in fertility of male patients was conducted among physicians nationwide. …”
Get full text

Impact of Out-of-pocket Costs on Varenicline Utilization and Persistence by Aaron Galaznik, Katherine Cappell, Leslie Montejano, Geoffrey Makinson, Kelly H. Zou, Gregory Lenhart

“…**Background:** Varenicline is a smoking cessation medication. **Objectives:** We analyzed patients’ out-of-pocket costs and utilization of and persistence with varenicline. …”
Get full text

Evaluation and diagnostic approach in patient with Perrault Syndrome by Rachael Christin Nathania, Steven Yulius Usman, Ekarini Aryasatiani

“…There was no history of prior medication, family illness, or chronic infections. Born at term via spontaneous vaginal delivery, the patient weighed 3,000 grams. …”
Get full text

Potential biomarkers in Behçet’s disease: monocyte, neutrophil, platelet, and C-reactive protein to albumin ratios by Mestan Sahin, Cansu Celin Karakose, Meltem Alkan Melikoglu

“…Demographic characteristics, disease duration, and current medications were recorded for all participants. The BD Current Activity Form (BDCAF) was utilized to assess the activity of BD. …”
Get full text

Improving natural red pigment production by Streptomyces phaeolivaceus strain GH27 for functionalization of textiles with in silico ADME prediction by Gehad H. El Sayed, Mohamed Fadel, Rasha Fouad, Hend M. Ahmed, Ahmed A. Hamed

“…The ADME physicochemical properties of the predominant medication were assessed, together with its bioavailability. …”
Get full text

The effect of L-dopa and DBS on cortical oscillations in Parkinson's disease analyzed by hidden Markov model algorithm by Kunzhou Wei, Hang Ping, Xiaochen Tang, Dianyou Li, Shikun Zhan, Bomin Sun, Xiangyan Kong, Chunyan Cao

“…Methods: 21 PD patients treated with medication underwent MEG recording in both L-dopa medoff and medon conditions. …”
Get full text