Anti-Inflammatory Effects of Cannabigerol In Vitro and In Vivo Are Mediated Through the JAK/STAT/NFκB Signaling Pathway by Ga Hee Jeong, Ki Chan Kim, Ji Hyun Lee

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Investigating the Structural Model of Predicting Sleep Disorders Through Symptoms of Rumination with the Mediating Role of Social Support in Dialysis Patients by Farhad Ghorbani, Amin Rafiepoor, Niloufar Tahmouresi, Reza, Hosseinpour

“…Structural equation modeling was employed for data analysis.Results: The results indicated that social support serves as a mediating factor in the relationship between rumination and sleep disorders. …”
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The impact of parental phubbing on social withdrawal in preschool children: the serial mediating roles of parent–child conflict and negative emotions by Pan Zhang, Xiaoying Wang

“…To address this gap, the present study constructed a chain mediation model to examine the association between parental phubbing and social withdrawal in preschool children, by introducing two mediating variables—parent–child conflict and negative emotions. …”
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Immune Mediator Profile in Aqueous Humor Differs in Patients with Primary Acquired Ocular Toxoplasmosis and Recurrent Acute Ocular Toxoplasmosis by Claudia Thieme, Stephan Schlickeiser, Sylvia Metzner, Claudia Dames, Uwe Pleyer

“…Mediators of Inflammation…”
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Mycoplasma pneumoniae drives macrophage lipid uptake via GlpD-mediated oxidation, facilitating foam cell formation by Takeshi Yamamoto, Miki Okuno, Koichi Kuwano, Yoshitoshi Ogura

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Linking employee voice to service recovery performance in the hotel sector: The mediating role of tacit knowledge sharing and employee innovation by Sultan Alzyoud, Waed Ensour, Ayman Harb

“…The findings demonstrated that tacit knowledge plays apartial mediating role in the association between employee voice and employee innovation. …”
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hERG activators exhibit antitumor effects in breast cancer through calcineurin and β-catenin-mediated signaling pathways by Yan Yu, Chengchun Zhu, Xiao Wang, Ying Shi, Yiping Gao, Zhiyi Yu

“…Mechanistically, the anti-proliferative activity of hERG activators were mediated through calcineurin activation via enhanced calcium ion influx, which facilitated the nuclear translocation of nuclear factor of activated T cells (NFAT) and upregulated p21Waf/Cip expression. …”
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RASGRF2 as a potential pathogenic gene mediating the progression of alcoholic hepatitis to alcohol-related cirrhosis and hepatocellular carcinoma by Zhengyuan Chen, Danfeng Fan, Tianyi Hang, Xiaoqing Yue

“…Conclusion RASGRF2 serve as a pathogenic gene that mediates the progression of AH to AC and potentially to HCC.…”
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Chinese Medicine Huzhen Tongfeng Formula Effectively Attenuates Gouty Arthritis by Inhibiting Arachidonic Acid Metabolism and Inflammatory Mediators by Jianping Deng, Zicong Wu, Chen Chen, Zhenling Zhao, Yifei Li, Zhengquan Su, Yiguang Lin, Yifei Wang, Zhiping Wang

“…Mediators of Inflammation…”
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Akkermansia muciniphila Mediated the Preventive Effect of Disulfiram on Acute Liver Injury via PI3K/Akt Pathway by Ruonan Zhang, Xuewei Sun, Han Lu, Xinrui Zhang, Mingyan Zhang, Xuewen Ji, Xinyi Yu, Chengliang Tang, Zihan Wu, Yinghua Mao, Jin Zhu, Minjun Ji, Zhan Yang

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The relationship between borderline personality features and self-efficacy: the mediating role of school adjustment and the moderating role of social support by Tengfei Yu, Xiaodi Niu, Liran Fu, Liju Qian

“…Results (1) Adolescents' school adjustment and self-efficacy were negatively associated with borderline personality features. (2) The relationship between borderline personality features and self-efficacy was partially mediated by school adjustment. (3) The relationships among borderline personality features, school adjustment, and self-efficacy were moderated by social support. …”
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Inflammatory Mediators in Induced Sputum and Airway Hyperresponsiveness in Cough Variant Asthma during Long-Term Inhaled Corticosteroid Treatment by Meixuan Liu, Kaixiong Liu, Ning Zhu, Jingwen Xia, Xiaodong Chen

“…Mediators of Inflammation…”
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Exploring the anti-metastatic potential of sunitinib and novel analogs in colorectal cancer: insights into HIF-1α mediated metastasis by Fatemeh B. Rassouli, Maryam M. Matin, Maryam M. Matin, Farzin Hadizadeh, Farzin Hadizadeh, Masoud Nejabat, Hossein Allahverdizadeh, Hamidreza Jamali, Shahin Gharedaghi, Halimeh Hassanzadeh

“…For in vitro studies, analogs of sunitinib were synthesized, and cells were assessed for viability, migration, invasion, MMPs activity and gene expression in hypoxic condition.Results and DiscussionComputational analyses highlighted the importance of HIF-1α as a crucial mediator of metastasis in CRC. Molecular docking and dynamics simulations demonstrated favorable and stable interaction of sunitinib and three novel analogs with HIF-1α PAS-B domain. …”
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Anti-PD-1 exacerbates bleomycin-induced lung injury in mice via Caspase-3/GSDME-mediated pyroptosis by Fei Wang, Haiyi Deng, Maolin Zhou, Yilin Yang, Jiankui Zhou, Yansheng Wang, Xiaohong Xie, Xinqing Lin, Ming Liu, Gengyun Sun, Chengzhi Zhou

“…Our results suggest that GSDME-mediated pyroptosis may be associated with the pathogenesis of ICI-LI, indicating that targeting GSDME could be a potential therapeutic strategy for treating ICI-LI.…”
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Patients Who Fainted Whilst Giving a Blood Sample in the Blood Collectıon Unit and a Stress Mediator: Cortisol by Şenol Arslan, Mevlana Ömeroğlu

“…OBJECTIVE: Cortisol is a glucocorticoid and can be used as a stress mediator in association with adrenal insufficiency. …”
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Tumor-infiltrating lymphocytes mediate complete and durable remission in a patient with NY-ESO-1 expressing prostate cancer by Elke Jäger, Julia Karbach, Claudia Wahle, Dragan Kiselicki, Kathrin Brand, Evgueni Sinelnikov, Dirk Gustavus, Hans Hoffmeister, Hans-Bernd Prisack, Akin Atmaca

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Enhanced motivated behavior mediated by pharmacological targeting of the FGF14/Nav1.6 complex in nucleus accumbens neurons by Nolan M. Dvorak, Paul A. Wadsworth, Guillermo Aquino-Miranda, Pingyuan Wang, Douglas S. Engelke, Jingheng Zhou, Nghi Nguyen, Aditya K. Singh, Giuseppe Aceto, Zahra Haghighijoo, Isabella I. Smith, Nana Goode, Mingxiang Zhou, Yosef Avchalumov, Evan P. Troendle, Cynthia M. Tapia, Haiying Chen, Reid T. Powell, Timothy J. Baumgartner, Jully Singh, Leandra Koff, Jessica Di Re, Ann E. Wadsworth, Mate Marosi, Marc R. Azar, Kristina Elias, Paul Lehmann, Yorkiris M. Mármol Contreras, Poonam Shah, Hector Gutierrez, Thomas A. Green, Martin B. Ulmschneider, Marcello D’Ascenzo, Clifford Stephan, Guohong Cui, Fabricio H. Do Monte, Jia Zhou, Fernanda Laezza

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Comparative Efficacy of Antihypertensive Agents in Flow-Mediated Vasodilation of Patients with Hypertension: Network Meta-Analysis of Randomized Controlled Trial by Hong Ding, Shu Liu, Ke-Xin Zhao, Jie Pu, Ya-Fei Xie, Xiao-Wei Zhang

“…A popular and widely used noninvasive tool, flow-mediated dilation (FMD), is used to examine peripheral artery endothelium-dependent dilation. …”
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Ex Vivo Antioxidant Activity of Selected Medicinal Plants against Fenton Reaction-Mediated Oxidation of Biological Lipid Substrates by Namratha Pai Kotebagilu, Vanitha Reddy Palvai, Asna Urooj

“…Free radical-mediated oxidation is often linked to various degenerative diseases. …”
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Investigating the Effect of Effective Factors on Actual Purchase with the Mediating Role of Purchase Intention and the Moderating Role of Iranian Product Type by Aliakbar Shahri Mejarshin, Alireza Rousta, Abdullah Naami

“…Purpose: The primary purpose of this study is to investigate the factors affecting the actual or final purchase of Iranian goods by evaluating the mediation effect of purchase intention and the moderating role of Iranian product type. …”
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