Rap1 Guanosine Triphosphate Hydrolase (GTPase) Regulates Shear Stress-Mediated Adhesion of Mesenchymal Stromal Cells by Melanie Giesen, Erika Fleck, Jürgen Scheele, Tanja Nicole Hartmann, Reinhard Henschler

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Circulating Interleukin-6 (but Not Other Immune Mediators) Associates with Criteria for Fried’s Frailty among Very Old Adults by Gilberto Santos Morais Junior, Diego Ignacio Valenzuela Perez, Audrey Cecília Tonet-Furioso, Lucy Gomes, Karla Helena Coelho Vilaça, Vicente Paulo Alves, Clayton Franco Moraes, Otávio Toledo Nóbrega

“…The present research aimed to investigate the association of components of Fried’s frailty (as well as of the phenotype as a whole) with total serum levels of a panel of inflammatory mediators. Methods. One hundred and sixty-one very old patients (aged ≥80 years) devoid of cognitive decline were eligible for analyses. …”
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The Effect of Business Intelligence on Firm Performance Considering the Mediating Role of Knowledge Sharing, Organizational Innovation and Competitive Advantage by Hossein Norouzi, Soheila Khoddami, Zahra Abidi

“…Purpose: This study analyzes the effect of business intelligence on firm performance by considering the mediating role of knowledge sharing, organizational innovation, and competitive advantage.Methodology: This study is descriptive correlational research. …”
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Sigma1 inhibitor suppression of adaptive immune resistance mechanisms mediated by cancer cell derived extracellular vesicles by Paola A. Castagnino, Derick A. Haas, Luca Musante, Nathalia A. Tancler, Bach V. Tran, Rhonda Kean, Alexandra R. Steck, Luis A. Martinez, Elahe A. Mostaghel, D. Craig Hooper, Felix J. Kim

“…Here, we demonstrate that a selective small molecule inhibitor of Sigma1 can block IFN-γ mediated adaptive immune resistance in part by altering the incorporation of PD-L1 into cancer cell-derived EVs. …”
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Impact of gratitude on posttraumatic growth in patients with coronary stent implantation: the mediating role of resilience and perceived social support by Shanyan Lei, Yujie Zhang, Fang Yang

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Quorum sensing-mediated inter-specific conidial anastomosis tube fusion between Colletotrichum gloeosporioides and C. siamense by Nikita Mehta, Abhishek Baghela

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Peran Gratitude Sebagai Mediator Antara Perceived Teacher’s Social Support dan Purpose in Life Pada Remaja by Nurul Aisah, Livia Yuliawati

“…Data analysis was conducted using JASP 0.14.1 and hypothesis testing through mediation analysis with a causal steps model. The results of the mediation analysis showed that perceived teachers' social support has a significant influence on purpose in life through gratitude as a mediator variable, but the resulting mediation effect is partial. …”
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Tumor Necrosis Factor Alpha Mediates GABAA Receptor Trafficking to the Plasma Membrane of Spinal Cord Neurons In Vivo by Ellen D. Stück, Randolph N. Christensen, J. Russell Huie, C. Amy Tovar, Brandon A. Miller, Yvette S. Nout, Jacqueline C. Bresnahan, Michael S. Beattie, Adam R. Ferguson

“…GABAAR protein levels in membrane fractions of TNFα and vehicle-treated subjects were not significantly different by Western Blot, yet high-resolution quantitative confocal imaging revealed that TNFα induces GABAAR trafficking to synapses in a dose-dependent manner by 60 min. TNFα-mediated GABAAR trafficking represents a novel target for CNS excitotoxicity.…”
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Internal communication as a mediator in the relationship between transformational leadership and academic staff’s readiness for change in higher education by Saharudin Saharudin, Ekawarna Ekawarna, Urip Sulistiyo, Mohd. Odha Meditamar, Santo Kristiyono

“…Internal communication was found to mediate the relationship between transformational leadership and organizational change readiness on academic staff's readiness for change. …”
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The mediating effect of social support on the relationship between intimacy and perceived partner responsiveness in endometriosis women of childbearing age by Jia Chen, Jia Chen, Yuanjing Ge, Xiaohong Jin, Haiyan Huang, Xiao Shan, Xujuan Xu, Xujuan Xu

“…A four-step hierarchical regression analysis was conducted.ResultsPositive correlations were found among intimacy and subjective support, support utilization, and PPR. Mediation analysis indicated a partial mediating effect of support utilization on the relationship between intimacy and PPR.ConclusionThere is a positive correlation between intimacy and PPR in EM patients of childbearing age, and the support utilization plays a partial mediating role.…”
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Exploring how attachment insecurities mediate the link between sexual and partnership satisfaction in adolescents and young adults with cancer by Svenja Heyne, Hannah Brock, Diana Richter, Annekathrin Sender, Jenny Rosendahl, Michael Friedrich, Kristina Geue, Anja Mehnert-Theuerkauf

“…Sexual satisfaction partially predicted partnership satisfaction of AYA cancer survivors through attachment-related anxiety and attachment-related avoidance while the mediating effect accounted for 75% of the total effect. …”
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Pengaruh Resiliensi terhadap Psychological Well-Being dengan Dukungan Sosial sebagai Variabel Mediator pada Mahasiswa by Lili Dwi Novianti, Ilham Nur Alfian

“…Ditunjukkan bahwa dukungan sosial menjelaskan 25% dari total effect sehingga tergolong partial mediation. Hasil penelitian menunjukkan adanya pengaruh resiliensi terhadap psychological well-being dengan dimediasi oleh dukungan sosial dan jenis mediasi bersifat parsial.…”
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Correction: HOXB8 mediates resistance to cetuximab in colorectal cancer cells through activation of the STAT3 pathway by Yunan Liang, Han Lin, Zongsheng Jiang, Qi Zhao, Ri Cui, Shaotang Li

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PD‐1+CD8+ T Cell‐Mediated Hepatocyte Pyroptosis Promotes Progression of Murine Autoimmune Liver Disease by Jie Long, Si‐Yu Yang, Zhen‐Hua Bian, Hao‐Xian Zhu, Min Ma, Xiao‐Qing Wang, Liang Li, Weici Zhang, Ying Han, M. Eric Gershwin, Zhe‐Xiong Lian, Zhi‐Bin Zhao

“…Depletion of PD‐1+CD8+ T cells using CAR‐T cells effectively alleviates the disease. GSDMD‐mediated pyroptosis is found to be aberrantly activated in the livers of model mice, and treatment with a GSDMD‐specific inhibitor significantly inhibits disease progression. …”
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The mediating effects of self-concept on the relationship between parenting styles and young children’s social problem-solving in Türkiye by Ahmet Ayık, Türker Sezer, Sinan Koçyiğit

“…The aim of this study was to investigate the associations between parenting styles, young children’s social problem-solving skills, and the mediating role of self-concept in a sample of 200 Turkish preschoolers aged 48–72 months, with an equal distribution of male and female participants. …”
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Identification of ALEKSIN as a novel multi-IRF inhibitor of IRF- and STAT-mediated transcription in vascular inflammation and atherosclerosis by Aleksandra Antonczyk, Katarzyna Kluzek, Natalia Herbich, Mahdi Eskandarian Boroujeni, Bart Krist, Dorota Wronka, Anna Karlik, Lukasz Przybyl, Adam Plewinski, Joanna Wesoly, Hans A. R. Bluyssen

“…Together, this suggests that ALEKSIN represents a novel class of multi-IRF inhibitors, which inhibits IRF-, STAT-, and NF-κB-mediated transcription and could offer great promise for the treatment of CVDs. …”
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Ultrasound Microbubble-Mediated microRNA-505 Regulates Cervical Cancer Cell Growth via AKT2 by Leilei Xu, Qin Zhang, Changhua Li, Fu Hua, Xiaoping Liu

“…The application of ultrasound and microbubbles (USMB-) mediated microRNA (miR) is a promising approach of gene delivery for cancer treatment. …”
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Self-regulated Learning as a Mediator between Authoritative Parenting and Academic Achivement of Junior high School Students by Husnaini Husnaini, Rita Eka Izzaty

“…Based on both, the regression coefficient c' decreased, proving the existence of partial mediation. It can be concluded that there is a partial mediation effect of self-regulated learning from authoritative parenting on learning achievement.…”
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The effect of social support on academic performance among adolescents: The chain mediating roles of self-efficacy and learning engagement. by Xiangping Zhang, Wensheng Qian

“…It also seeks to explore the mediating roles of self-efficacy and learning engagement in this relationship.…”
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Mediating effect of sleep quality on relationship between job stress and mental health status among occupational population by Mengting LIU, Li NING, Xiaoyan GAO

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