Showing 1,481 - 1,500 results of 11,114 for search '"mediation"', query time: 0.13s Refine Results
  1. 1481
  2. 1482

    The Stability of a Model Substrate for Topoisomerase 1-Mediated DNA Religation Depends on the Presence of Mismatched Base Pairs by William H. Gmeiner, Freddie Salsbury, Chris M. Olsen, Luis A. Marky

    Published 2011-01-01
    “…The reduced efficiency for Top1-mediated religation contributes to the anticancer activity of widely used anticancer drugs including fluoropyrimidines and gemcitabine. …”
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    Article
  3. 1483

    TGFβ1-Induced Differentiation of Human Bone Marrow-Derived MSCs Is Mediated by Changes to the Actin Cytoskeleton by Mona Elsafadi, Muthurangan Manikandan, Sami Almalki, Mohammad Mobarak, Muhammad Atteya, Zafar Iqbal, Jamil Amjad Hashmi, Sameerah Shaheen, Nehad Alajez, Musaad Alfayez, Moustapha Kassem, Raed Abu Dawud, Amer Mahmood

    Published 2018-01-01
    “…To identify the mechanisms underlying this TGFβ-mediated enhancement of lineage commitment, we compared the gene expression profiles of TGFβ1-treated hMSC cultures using DNA microarrays. …”
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  4. 1484

    Sulforaphane enhances Nrf2-mediated antioxidant responses of skeletal muscle induced by exhaustive exercise in HIIT mice by Yangwenjie Wang, Yang Xiang, Ruiqi Wang, Xiangning Li, Jianxiong Wang, Siwang Yu, Ying Zhang

    Published 2022-09-01
    “…In the present study, we evaluated the effects of sulforaphane (SFN), a dietary isothiocyanate derived from cruciferous vegetables and a potent Nrf2 activator, on Nrf2-mediated antioxidant defense responses of skeletal muscle induced by exhaustive exercise in HIIT mice. …”
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    Article
  5. 1485

    Mediating Effect of Organizational Learning Capacity on the Relationship between Relational Embeddedness and Innovation Performance in Freight Logistics Service by Pengxia Bai, Qunqi Wu, Qian Li, Chenlei Xue, Lei Zhang

    Published 2021-01-01
    “…Meanwhile, OLC partially mediates the relationship between RE and IPFLS. The findings provide practical guidance for managers to strengthen the relationship with partners and enhance OLC.…”
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  6. 1486

    Metabolites and lipid species mediate the associations of adiposity in childhood and early adulthood with mammographic breast density in premenopausal women by Kayla R. Getz, Myung Sik Jeon, Lili Liu, Lei Liu, Haixiang Zhang, Chongliang Luo, Jingqin Luo, Adetunji T. Toriola

    Published 2025-02-01
    “…We performed high dimensional mediation analysis using the HIMA R package, adjusted for confounders, to determine whether lipid species and metabolites mediate the associations of BMI at 10 and 18 with MBD. …”
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  7. 1487

    Relationship Between Sleep Time and Depressive Symptoms in Middle-Aged and Elderly Chinese: Mediating Role of Body Pain by Yang Z, Li B, Ma D, Lv Y, Qiu X, Zhang W, Wang J, Zhang Y, Xu C, Deng Y, Li J, Zhen X, Zhang J

    Published 2025-01-01
    “…Body pain accounts for a 19.05% mediating effect between sleep time and depressive symptoms, and even after controlling confounding factors, there remains a 7.5% mediating effect.Conclusion: The research findings indicate that there is a significant correlation among sleep time, body pain, and depressive symptoms. …”
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  8. 1488
  9. 1489

    Identification of clinical subgroups in anti-SRP positive immune-mediated necrotizing myopathy patients using cluster analysis by Beibei Cui, Hongjiang Liu, Ruiting Liu, Geng Yin, Qibing Xie

    Published 2025-01-01
    “…Background: Anti-signal recognition particle immune-mediated necrotizing myopathy (anti-SRP IMNM) is a rare autoimmune disorder characterized by muscle weakness and necrosis. …”
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  10. 1490

    Phosphodiesterase 10A Is a Mediator of Osteogenic Differentiation and Mechanotransduction in Bone Marrow-Derived Mesenchymal Stromal Cells by Sigrid Müller-Deubert, Carolin Ege, Melanie Krug, Jutta Meißner-Weigl, Maximilian Rudert, Oliver Bischof, Franz Jakob, Regina Ebert

    Published 2020-01-01
    “…Mechanotransduction leads to the formation of second messengers such as cAMP, cGMP, or Ca2+ influx resulting in the activation of transcription factors mediating gene regulation. The second messengers cAMP and cGMP are degraded by phosphodiesterase isoenzymes (PDE), but the role of these enzymes during osteogenic differentiation or mechanotransduction remains unclear. …”
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    Article
  11. 1491
  12. 1492
  13. 1493

    Neuropilin 1 Mediates Keratinocyte Growth Factor Signaling in Adipose-Derived Stem Cells: Potential Involvement in Adipogenesis by Simona Ceccarelli, Cristina Nodale, Enrica Vescarelli, Paola Pontecorvi, Valeria Manganelli, Giovanni Casella, Maria Giuseppina Onesti, Maurizio Sorice, Ferdinando Romano, Antonio Angeloni, Cinzia Marchese

    Published 2018-01-01
    “…Our study contributes to clarify the molecular bases of human adipogenesis, demonstrating a role of KGF in the early steps of this process, and points out a role of NRP1 as a previously unknown mediator of KGF action in ASCs.…”
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  14. 1494
  15. 1495

    Sikap atas Produk Tiruan sebagai Mediator Kerentanan Konsumen terhadap Intensi Membeli Produk Fashion Tiruan by Angger Agung Permadi, Dewi Syarifah

    Published 2021-07-01
    “…Penelitian ini bertujuan untuk mengetahui pengaruh kerentanan konsumen terhadap intensi membeli produk fashion tiruan dengan sikap atas produk tiruan sebagai mediator. Laporan MIAP menunjukkan sebagian konsumen di Indonesia kurang memperhatikan keaslian produk ketika akan membeli suatu produk fashion, akibatnya banyak diantara masyarakat yang kemudian membeli produk fashion tiruan. …”
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  16. 1496

    The Relationship between Personality Structures and Moral Development: Mediating Role of Mind Reading in the Students of Farhangian University of Kerman by Mohammad Esmaeilzadeh, Hamdollah Manzari Tavakoli, Mitra Kamyabi, Amanollah Soltani

    Published 2024-03-01
    “…Furthermore, the results indicated that the dimensions of mind reading ability significantly mediated the relationship between personality traits and moral development. …”
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    Article
  17. 1497

    The Role of Social Support to Foster Creative Thinking of Vocational Students In University: Mediating Effect of Creative Self-Efficacys by Ida Nugroho Saputro, Sukatiman Sukatiman, Abdul Haris Setiawan, Ayu Intan Sari

    Published 2024-09-01
    “…Creative self-efficacy only significantly mediates the effect of lecturer support on creative thinking. …”
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  18. 1498

    Religiosity as a potential mediator for violence in childhood and adulthood: results from a Brazilian nationally representative survey by Homero Vallada, Ronaldo Laranjeira, Juliane Piasseschi de Bernardin Gonçalves, Giancarlo Lucchetti, Maria do Rosario Dias Latorre

    Published 2022-06-01
    “…However, while there was a significant association between suffering violence during childhood and suffering and/or perpetrating violence in adulthood, religiosity did not mediate this relationship.Conclusions Although religious individuals self-reported less violence suffered in childhood, religiosity did not show evidence of being a potential mediator for childhood and adulthood violence (experienced and/or perpetrated). …”
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  19. 1499

    Pseudomonas aeruginosa pili and flagella mediate distinct binding and signaling events at the apical and basolateral surface of airway epithelium. by Iwona Bucior, Julia F Pielage, Joanne N Engel

    Published 2012-01-01
    “…At the BL surface, flagella-mediated binding to HS activates the epidermal growth factor receptor (EGFR), adaptor protein Shc, and PI3K/Akt, and induces bacterial entry. …”
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