Acute phase responses in clinically healthy multiparous Holsteins with and without calcium dysregulation during the early postpartum period by J.A. Seminara, C.R. Seely, J.A.A. McArt

“…The acute phase response produces markers and mediators of inflammation; therefore, the objective of our case-control study was to evaluate postpartum patterns of 3 positive acute phase proteins in cows with and without dyscalcemia. …”
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USP14 inhibition by degrasyn induces YAP1 degradation and suppresses the progression of radioresistant esophageal cancer by Fang Yuan, Juan Xu, Lingmei Xuan, Chan Deng, Wei Wang, Rong Yang

“…Ubiquitin-specific peptidase 14 (USP14) is a novel deubiquitinase and can mediate cancer cells’ response to irradiation, although the underlying mechanism remains unclear, including in ESCA. …”
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Phenotypes of primary sclerosing cholangitis in children by M.B. Dyba, V.S. Berezenko

“…Primary sclerosing cholangitis (PSC) in children is a rare chronic immune-mediated disease of the biliary tract, which, unlike in adults, has a less aggressive course with da­mage to the intrahepatic bile ducts and is combined with autoimmune hepatitis, creating a special clinical phenotype of PSC, autoimmune sclerosing cholangitis (ASC). …”
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Protective mechanism of safflower yellow injection on myocardial ischemia-reperfusion injury in rats by activating NLRP3 inflammasome by Lingmei Li, Ce Cao, Hao Guo, Li Lin, Lei Li, Yehao Zhang, Gaojie Xin, Zixin Liu, Shujuan Xu, Xiao Han, Qiong Zhang, Jianhua Fu

“…Abstract Objectives This study intended to explore whether the protective effect safflower yellow injection (SYI) on myocardial ischemia-reperfusion (I/R) injury in rats mediated of the NLRP3 inflammasome signaling. Methods The I/R model was prepared by ligating the left anterior descending coronary artery for 45 min and then releasing the blood flow for 150 min. 96 male Wistar rats were randomly divided into sham group, I/R group, Hebeishuang group (HBS), SYI high-dose group (I/R + SYI-H), SYI medium-dose group (I/R + SYI-M) and SYI low-dose group (I/R + SYI-L). …”
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The generation and evaluation of TKO/hCD55/hTM/hEPCR gene-modified pigs for clinical organ xenotransplantation by Guoli Huai, Yong Wang, Jiaxiang Du, Zhenhui Cheng, Yuxuan Xie, Jia Zhou, Hongmei Tang, Yanyan Jiang, Xiangyang Xing, Shaoping Deng, Dengke Pan, Dengke Pan, Dengke Pan

“…Similar to TKO/hCD55 pAECs, 6GE pAECs exhibited a substantial reduction in complement-mediated cytotoxicity (p<0.001) compared to TKO pAECs. …”
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Functional assessment of the glycoproteins of a novel Hendra virus variant reveals contrasting fusogenic capacities of the receptor-binding and fusion glycoproteins by Andrew Z. Ma, Yao Yu Yeo, Jean F. Lee, Colin M. Kim, Shahrzad Ezzatpour, Carolina Menchaca, Viraj Upadhye, Edward J. Annand, John-Sebastian Eden, Raina K. Plowright, Alison J. Peel, David W. Buchholz, Hector C. Aguilar

“…As the receptor-binding (G) and fusion (F) glycoproteins of HeV are essential for mediating viral entry, functional characterization of emerging HeV genotypic variants is key to understanding viral entry mechanisms and broader virus-host co-evolution. …”
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PreS1 deletions in genotype C HBV leads to severe hepatic inflammation and hepatocarcinogenesis via the IRE1-JNK axis by Yu-Min Choi, Junghwa Jang, Dong Hyun Kim, Ziyun Kim, Eunseo Kim, Won Hyeok Choe, Bum-Joon Kim

“…Conclusions: PreS1Del leads to enhanced HBV replication and HCC development through IRE1-JNK-IL6/COX2-mediated hepatocyte proliferation and liver inflammation. …”
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Global phylogeography and genetic characterization of carbapenem and ceftazidime-avibactam resistant KPC-33-producing Pseudomonas aeruginosa by Longjie Zhou, Jiayao Yao, Ying Zhang, Xiaofan Zhang, Yueyue Hu, Haiyang Liu, Jintao He, Yunsong Yu, Minhua Chen, Yuexing Tu, Xi Li

“…However, KPC variants have become the main mechanism mediating CZA resistance in KPC-producing gram-negative bacteria after increasing the application of CZA. …”
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Disrupting EDEM3‐induced M2‐like macrophage trafficking by glucose restriction overcomes resistance to PD‐1/PD‐L1 blockade by Shaoyong Peng, Minshan Wu, Qian Yan, Gaopo Xu, Yumo Xie, Guannan Tang, Jinxin Lin, Zixu Yuan, Xiaoxia Liang, Ze Yuan, Jingrong Weng, Liangliang Bai, Xiaolin Wang, Huichuan Yu, Meijin Huang, Yanxin Luo, Xiaoxia Liu

“…Additionally, EDEM3 plays a role in tumour immunityduring tumour progression. However, the EDEM3‐mediated upregulation of PD‐L1 expression underpins PD‐1/PD‐L1 blockade resistance in vivo. …”
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Presenting the model of antecedents affecting moral-emotional acting in education by arefeh kazemi malekmahmoudi, negin jabbari, kiomars niaz azari

“….- Education: It is an educational organization responsible for the education of children and teenagers as well as the training of teachers (Hyati et al, 2023).Kang & Jang (2022) conducted a research titled emotional labor of frontline employees towards their colleagues: the mediating role of team members' exchanges. In this research, the relationship between emotional labor of employees towards their colleagues and turnover intention was investigated by mediating the exchanges and supervisory listening, and the results showed that the relationship between employees' emotional labor towards their colleagues and the intention to leave the job is moderated by team member exchange, but the moderating effect of supervisory listening was found between surface action towards colleagues and team member exchange.Nixon et al, (2020) in a research aimed at investigating the effect of collective values ​​(culture) at the national and individual level on emotional acting strategies and employee pressure, emotional stress, turnover goals, job satisfaction and organizational commitment showed that collective values (culture) directly and reciprocally affect the emotional acting process model. …”
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Analysis of the impact of the quality of service to the elderly on their loyalty through a Memorable experience and satisfaction among the elderly in 5-star hotels in Mashhad. by tina ezazi, vajihe hoshyar

“…The effect of service quality through customer satisfaction on customer loyalty has been calculated equal to (0.07), which indicates a favorable effect. The mediator's role is confirmed in recent hypotheses.   …”
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Presenting the indigenous model of organizational self-leadership with an emphasis on training in non-governmental organizations by Sajad Ghoreishi, abbas abbaspour, Mostafa Niknami, Morteza Taheri

“…In a research titled investigating the role of self-leadership strategies on employee creativity as a mediator of career success, Shamkhani, Kazemi Laegh (2023) finally concluded that self-leadership strategy has a positive and significant effect on creativity with a role as a mediator of employee career success. …”
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Design and validation of consumer behavior model based on user-generated content in the banking industry by Sepahdar Rahnama, Marzieh ZendehDel, Mir Hadi Moazen Jamshidi

“…In fact, any form of content, which is produced outside of professional structures, is called user-generated content, usually disseminated in social platforms and technologies including social networks, social computing, web 2, collective action tools, social web, read/write web, Customer-generated networks, virtual communities, computer-mediated communication, socio-technical systems (Koivisto & Mattila, 2018). …”
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Overexpression of the <i>GmPM35</i> Gene Significantly Enhances Drought Tolerance in Transgenic Arabidopsis and Soybean by Xinyu Wang, Yao Sun, Rui Wang, Xinyang Li, Yongyi Li, Tianyu Wang, Zhaohao Guo, Yan Li, Wenxi Qiu, Shuyan Guan, Qi Zhang, Piwu Wang, Mingze Li, Siyan Liu, Xuhong Fan

“…To further investigate the drought tolerance function of this gene in soybeans, nine overexpression lines of the T₃ generation soybean <i>GmPM35</i> gene and two editing lines of the T₃ generation soybean <i>GmPM35</i> gene were obtained by Agrobacterium-mediated method using a wild-type soybean strain (JN28) as a receptor. …”
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Evaluation of Southern African wild edible plants for potential herb-drug interactions through ex vivo p-glycoprotein and in vitro cytochrome P450 3A4 inhibitory effects by P.S. Kheoane, K.C. Mokhetho, S. Mokhele, K.C. Mbara, C.M. Leonard, T.H. Gadaga, C. Tarirai

“…Conclusion: The observed inhibitory effects of certain wild edible plants on P-gp-mediated drug efflux and CYP3A4 drug metabolism indicate potential food/herb-drug interactions challenges for clinical practice. …”
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Diplomacy and Recruitment of Mercenaries before the Battle of Žalgiris by Sven Ekdahl

“…Sigismund now decided to replace his brother Venceslas as a mediator and arranged a meeting with Vytautas in the Hungarian city of Klismark (the German name; in Hungarian Kesmark, in Polish Kiezmark, today Kežmarok in Slovakia). …”
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Effect of the Iridoid-rich Fraction from <italic>Valeriana jatamansi</italic> Jones on Oxidative Stress in Rats with Spinal Cord Injury by Jiaojuan HUANG, Wenchun WANG, Deqi XIONG, Hao LU, Wu XIANG, Xiaohua ZHAO, Ruihan ZHOU, Anren ZHANG

“…The rats were sacrificed on third days after administration, and the contents of oxidative stress indexes superoxide dismutase(SOD)and malondialdehyde(MDA)in serum were detected by enzyme linked immunosorbent assay(ELISA); the related biochemical kit was used to test glutathione peroxidase(GSH-PX)and catalase(CAT)viability of the spinal cord tissue; the expression levels of apoptosis-related proteins of Caspase-3, B cell lymphoma(Bcl-2)associated X protein(Bax), and Bcl-2 were detected by Western blot; and the Hematoxylin/eosin(HE)staining was used to observe the pathological changes of the spinal cord tissue at the perilesional area; and Terminal-deoxynucleoitidyl transferase mediated nick end labeling(TUNEL)was used to observe the apoptosis of nerve cells of the spinal cord tissue at the perilesional area.Results:The results of ELISA showed that compared with the sham-operated group, the SOD content in the serum of the model group decreased, and the MDA content increased; compared with the model group, the SOD content in the serum of the treatment group with iridoid-rich fraction from <italic>Valeriana jatamansi</italic> Jones increased significantly(<italic>P</italic>&lt; 0.05), and the MDA content decreased significantly(<italic>P</italic>&lt; 0.01). …”
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Effect of integrin α5 on NLRP3 expression in periodontal ligament fibroblasts within an inflammatory microenvironment by DAI Jingyi, CAI Hongxuan, SI Weixing, ZHANG Zan, WANG Zhurui, LI Mengsen, TIAN Ya guang

“…Conclusion <i>In vitro</i> and <i>in vivo</i> experiments showed that integrin α5 mediated NLRP3 expression in PDLFs under an inflammatory microenvironment. …”
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Designing a causal model of factors affecting the Lars supply chain by mojtaba khalesi, mojdeh rabani, Hasan Dehghan Dahnavi, Abolfazl Sadeghian, mohammad taghi honari

“…In other words, supply chain innovation can play a mediating role in the relationship between supply chain analysis and robustness. …”
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Authority and Moral Conflicts in the Films of Adébáyọ Fálétí: Àfọ̀njá, Gáà, Ṣawo Ṣẹ̀gbẹ̀rì and the Yorùbá Cosmopolis by Olayinka Agbetuyi

“…In Àfọ̀njá and Gáà that context is provided by the empire phase of Yorùbá civilization in which Yorùbá civilization was the dominant point of reference; in Ṣawo Ṣẹgbẹ ̀ rì ̀ the drama is situated in the context of postcolonial Nigerian city, in a nation that boasts large ethnic nationalities of which the Yorùbá are only one and in which Yorùbá culture is mediated by the postcolonial state with its symbol of the English language as the means of communication and its cultural spin offs. …”
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