Unraveling the immunological landscape and gut microbiome in sepsis: a comprehensive approach to diagnosis and prognosisResearch in context by Yali Luo, Jian Gao, Xinliang Su, Helian Li, Yingcen Li, Wenhao Qi, Xuling Han, Jingxuan Han, Yiran Zhao, Alin Zhang, Yan Zheng, Feng Qian, Hongyu He

“…These changes statistically mediated the association of Bacteroides salyersiae with sepsis, suggesting a potential underlying mechanism. …”
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Ethanolamine-induced assembly of microcompartments is required for Fusobacterium nucleatum virulence by Dana S. Franklin, Yi-Wei Chen, Yimin Chen, Manuel Wittchen, Angela Agnew, Alexis Luu, Julian P. Whitelegge, Z. Hong Zhou, Andreas Tauch, Asis Das, Hung Ton-That

“…Together, these results establish that the BMC-mediated metabolism of ethanolamine is critical for fusobacterial virulence.IMPORTANCEThe oral anaerobe Fusobacterium nucleatum can spread to distal internal organs, such as the colon and placenta, thereby promoting the development of colorectal cancer and inducing preterm birth, respectively. …”
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Genomic insights into the alphaproteobacterium Georhizobium sp. MAB10 revealed a pathway of Mn(II) oxidation-coupled anoxygenic photoautotrophy: a novel understanding of the biotic... by Xiuli Xu, Litao Zhang, Fuhang Song, Guoliang Zhang, Linlin Ma, Na Yang

“…These analyses provided insights into bacterial Mn(II) oxidation-coupled anoxygenic photoautotrophy during microorganism-mediated deep-sea ferromanganese nodule formation.IMPORTANCEMicroorganisms are believed to participate in the biotic process of deep-sea ferromanganese nodule formation [Mn(II) oxidation]. …”
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Yunvjian decoction attenuates lipopolysaccharide-induced acute lung injury by inhibiting NF-κB/NLRP3 pathway and pyroptosis by Fanxuan Zhang, Fang Wang, Lisha Zhao, Leqian Wang, Wenjing Li, Feihua Huang, Feihua Huang, Nani Wang, Nani Wang

“…Analysis of pneumonia-related lung injury samples from patients in the Gene Expression Omnibus dataset GSE40012 indicated that NOD-like receptor protein 3 (NLRP3)-mediated pyroptosis was a primary mechanism in ALI. …”
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Rancang Bangun Sistem Informasi Afiliasi Penjualan Tiket Seminar berbasis Website menggunakan Framework Laravel by Dimas Kurnia Pratama, Adi Suryaputra Paramita

“…Based on research result, affiliation system is able to mediate the needs between eo and sales in event ticket sales calculation. …”
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Revealing novel protein interaction partners of glyphosate in Escherichia coli by Alix Sarah Aldehoff, Dominique Türkowsky, Patrick Lohmann, Masun Nabhan Homsi, Ulrike Rolle–Kampczyk, Elke Ueberham, Jörg Lehmann, Martin von Bergen, Nico Jehmlich, Sven–Bastiaan Haange

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Construire des ressources relationnelles pour franchir des frontières multiples : Trajectoires de jeunes Tunisiens by Hasnia-Sonia Missaoui

“…We collected several social trajectories of “unemployed graduates” a few years after the overthrow of President Zine el-Abidine Ben Ali’s regime on January 14, 2011 in order to understand how the bubbling of democratic expression carried by powerful collective mobilization movements linked to the end of the dictatorship can influence the daily life of an age group that is particularly mediatized but invisibilized or instrumentalized by the public authorities. …”
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Role of Psychological Distress in the Assessment of Chronic Illness Care and Self-Management Behaviors of Elderly Patients with T2DM Chronic Complications by Sun X, Wang X, Zhou R, Deng W, Jiang J, Shi Y

“…Furthermore, the total effect of PAID-C on DSMB-O via PACIC was determined to be (0.27+0.22=0.49). Notably, the mediating effect accounted for 54.99%.Conclusion: Psychological distress is intricately linked to self-management behaviour among elderly patients suffering from T2DM and chronic complications. …”
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Examining the Impact of Cognitive and Emotional Factors on Consumer Behavioral Responses in Online Behavioral Advertising by Hossein Norouzi, Bahareh Osanlou, Ali Saleh Gohari

“…Moreover, perceived relevance and perceived intrusiveness serve as mediators in the relationship between perceived personalization and behavioral responses to advertisements.   …”
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Cellular Cholesterol Loss Impairs Synaptic Vesicle Mobility via the CAMK2/Synapsin-1 Signaling Pathway by Atikam Qurban, Mengqi Zhang, Hengbing Zu, Kai Yao

“…Conversely, elevated cellular cholesterol levels caused by knock-in of DHCR24 reversed the effects of cholesterol deficiency, suggesting that CAMK2-mediated synapsin-1 phosphorylation may be regulated in a lipid raft-associated manner. …”
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Hypoxia specifically induces CADM3 expression in pulmonary endothelial cells and promotes monocyte adhesion by MENG Xiangqiong, MENG Xiangqiong, CHEN Ting, CHEN Ting

“…Objective‍　‍To investigate the expression profile of cell adhesion molecular 3 （CADM3） on pulmonary endothelial cells， analyze its role in mediating specific adhesion to monocyte， and explore a new mechanism of hypoxia inducing peripheral monocyte infiltration in pulmonary vessels. …”
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Diversity in mitotic DNA repair efficiencies between commercial inbred maize lines and native Central American purple landraces by Carlos Víquez-Zamora, Sergio Castro-Pacheco, María Viñas, Pablo Bolaños-Villegas

“…The kinase gene ZeaATM1 was sequenced, and results indicate that in lines P1 and P2 there are polymorphisms near and within the FATC domain, a domain required for the activation of ATM1-mediated repair of DNA damage. Conclusions Significant differences in DNA repair efficiency exist between inbred lines and landraces of maize and may be linked to allelic diversity in key genes for homologous recombination. …”
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Pairs and his role in pattem of trade in Vilnius and Kaunas province in 1861-1914 by Aelita Ambrulevičiūtė

“…There, artisans and farmers, making for the market, could sell their products without a mediator. That is why the increasing number of fairs was one effect of the growth of the commercialization of agriculture, integration of the peasant's economy into the market, and his conversion into an entrepreneur. …”
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Platelet-derived HMGB1 induces NETosis, exacerbating brain damage in the photothrombotic stroke model by Sang-A. Oh, Song-I. Seol, Dashdulam Davaanyam, Seung-Woo Kim, Ja-Kyeong Lee

“…HMGB1, particularly platelet-derived HMGB1, emerges as a key mediator to this process. Therefore, targeting NETosis through modulation of HMGB1 presents a promising multipotent therapeutic strategy for mitigating ischemic brain damage.…”
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Effectiveness of app-based cognitive behavioral therapy for insomnia on preventing major depressive disorder in youth with insomnia and subclinical depression: A randomized clinica... by Si-Jing Chen, Jian-Yu Que, Ngan Yin Chan, Le Shi, Shirley Xin Li, Joey Wing Yan Chan, Weizhen Huang, Chris Xie Chen, Chi Ching Tsang, Yuen Lam Ho, Charles M Morin, Ji-Hui Zhang, Lin Lu, Yun Kwok Wing

“…In addition, the CBT-I group reported a greater decrease in depressive (adjusted difference -1.0 [-1.6 to -0.5]; Cohen's d = 0.53; p < 0.001) and insomnia symptoms (-2.0 [-2.7 to -1.3], d = 0.78; p < 0.001) than the controls at post-intervention and throughout 6-month follow-up. Insomnia was a mediator of intervention effects on depression. No adverse events related to the interventions were reported.…”
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Preventing epileptogenesis by interaction between inositol isomers and proteins by Lia Tsverava, Luka Kharkhelauri, Vincenzo Lagani, Giorgi Gamkrelidze, Veriko Bokuchava, Tamar Kiguradze, Merab Kokaia, Revaz Solomonia

“…Myo‐inositol (MI), the most prevalent isomer, functions as an osmolyte and mediates cell signal transduction. Other notable isomers include Scyllo‐inositol (SCI) and D‐Chiro‐inositol (DCHI). …”
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CCR7 and CD48 as Predicted Targets in Acute Rejection Related to M1 Macrophage after Pediatric Kidney Transplantation by Jie Zhang, Jun Pei, Chengjun Yu, Jin Luo, Yifan Hong, Yi Hua, Guanghui Wei

“…GO and KEGG enrichment analysis showed that these genes are mainly involved in cytokine binding, antigen binding, NK cell-mediated cytotoxicity, activation of immune receptors and immune response, and activation of the inflammatory NF-κB signaling pathway. …”
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Major facility superfamily sugar transporter protein SsMFSST1 regulates Sporisorium scitamineum mating, pathogenicity, and sugar transport/absorption by Yi Zhang, Yongding He, Meixin Yan, Shilong Zhang, Sisi Zhou, Wankuan Shen

“…Knockout mutants (∆SsMFSST1+ and ∆SsMFSST1−) and complementary mutants (COMMFSST1+ and COMMFSST1−) were obtained through polyethylene glycol (PEG)-mediated protoplast transformation technology. On this basis, the function of gene SsMFSST1 was analyzed. …”
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Circular RNA RHOT1 Regulates miR-142-5p/CCND1 to Participate in Chondrocyte Autophagy and Proliferation in Osteoarthritis by Gu Man, Haiwen Yang, Kai Shen, Donghong Zhang, Julin Zhang, Hao Wu, Hongyu Zhang, Jinhuan Wang

“…The overexpression of CCND1 or the inhibition of miR-142-5p reversed circRHOT1 depletion-mediated chondrocyte phenotypes. Conclusions. Circular RNA RHOT1 enhances the CCND1 expression by sponging miR-142-5p to inhibit chondrocyte autophagy and promote chondrocyte proliferation in osteoarthritis. …”
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Evaluation of the Feasibility of Transfusing Leukocyte Depletion Filter–Processed Intraoperative Cell Salvage Blood in Metastatic Spine Tumor Surgery: Protocol for a Non–Randomized... by Naresh Kumar, Si Jian Hui, Renick Lee, Sahil Athia, Joel Yong Hao Tan, Jonathan Jiong Hao Tan

“…Allogeneic blood transfusion (ABT) is the mainstay of blood replenishment but with immune-mediated postoperative complications. Alternative blood management techniques (salvaged blood transfusion [SBT]) allow us to overcome such complications. …”
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