Development and characterization of a reverse genetic system for studying dengue virus serotype 3 strain variation and neutralization. by William B Messer, Boyd Yount, Kari E Hacker, Eric F Donaldson, Jeremy P Huynh, Aravinda M de Silva, Ralph S Baric

“…The observed variability in neutralization titers suggests that relatively few residue changes in the E glycoprotein may have significant effects on DENV specific humoral immunity and influence antibody mediated protection or disease enhancement in the setting of both natural infection and vaccination. …”
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Gene Expression of CD70 and CD27 Is Increased in Alopecia Areata Lesions and Associated with Disease Severity and Activity by Radwa El- Sayed Mahmoud Marie, Noha M. Abd El-Fadeel, Yara El-Sayed Marei, Lina M. Atef

“…Alopecia areata (AA) is an acquired hair loss disorder induced by a cell-mediated autoimmune attack against anagen hair follicles. …”
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Evaluation of global DNA methylation, homocysteine and vitamin B12 levels among patients with celiac disease by Farah Tareq Yaseen, Rakad M.Kh. Al-Jumaily

“…Celiac disease (CD) is an immune-mediated disorder caused by gluten in genetically susceptible individuals characterized by chronic inflammation that essentially affects the small intestine. …”
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Emodin promotes the recovery of rheumatoid arthritis by regulating the crosstalk between macrophage subsets and synovial fibroblast subsets by Lianying Cheng, Xiaofeng Rong

“…Moreover, MerTKposTREM2high STM‐mediated secretion of exosomes was promoted, which can inhibit the secretion of pro‐inflammatory factors by FAPα+THY1+ FLSs and promote the secretion of anti‐inflammatory factors by FAPα+THY1+ FLSs, thereby inhibiting FAPα+THY1−FLS proliferation and migration, improving the local immune microenvironment, and inhibiting RA damage. …”
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Relationship of Serum IL-12 to Inflammation, Hematoma Volume, and Prognosis in Patients With Intracerebral Hemorrhage by Yazhao Zhang, Yanan Tian, Jianhui Wei, Yi Xiang

“…Interleukin-12 (IL-12) promotes brain inflammation, and regulates coagulation mediated by red blood cells and platelets. This study was designed to investigate the relationship of serum IL-12 to inflammation, hematoma volume, and prognosis in ICH patients. …”
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A Study of Occupational Therapy Strategies and Psychological Regulation of Students’ Internet Addiction in the Mobile Social Media Environment by Xueqin Zhang

“…Student peer attachment significantly and positively predicted adolescent Internet addiction; Internet use peer pressure played an incomplete mediating role in the prediction of peer attachment to Internet addiction; loneliness played a moderating role in the pathway of peer attachment to Internet addiction, and loneliness also played a moderating role in the pathway of peer attachment to Internet use peer pressure. …”
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Adipokines in Breast Cancer: Decoding Genetic and Proteomic Mechanisms Underlying Migration, Invasion, and Proliferation by Ließem A, Leimer U, Germann GK, Köllensperger E

“…Migration and invasion behaviors were quantified using specialized Boyden chamber assays.Results: We found significant, adipokine-mediated genetic and proteomic alterations, with PCR showing an up to 6-fold increase of numerous malignancy-associated genes after adipokine-supplementation. …”
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Efficacy and safety of hemoporfin photodynamic therapy in treating port-wine stains in Chinese children: a systematic review and meta-analysis by Jing Xu, Hongxin Li

“…ObjectiveThe purpose of this study is to explore the efficacy and safety of hematoporphyrin monomethyl ether mediated photodynamic therapy (HMME-PDT) in treating children with port-wine stains (PWS).MethodLiterature related to the topic was searched in PubMed, Embase, Cochrane Library, Web of Science, China National Knowledge Infrastructure, Wanfang, and China Science Technology Journal Database online databases. …”
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THE ROLE OF US IN CHINA – TAIWAN CRISIS by EDGAR AGUBAMAH

“…Be that as it may this work recommended that the US should abandon her partial strategic ambiguity (that is they will not commit to go to war to defend Taiwan, nor will they take the war option off the table if Taiwan is attacked) and other subtle supports to Taiwan and play a clear and transparent mutual meditative role in China-Taiwan crisis so that the issue between China and Taiwan can be settled amicably. A truthful mediator must prove herself or himself impartial. …”
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Gene expression profiling in B-cell non-Hodgkin lymphomas by Renas N. Saleem, Ahmed Khudair Yassin

“…PATIENTS, MATERIALS AND METHODS: The current clinical prospective study was mediated from June 1, 2021, to December 30, 2022, of NHL patients in Kurdistan, Iraq. …”
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Severe Plasmodium falciparum malaria is associated with circulating ultra-large von Willebrand multimers and ADAMTS13 inhibition. by Deirdre Larkin, Bas de Laat, P Vince Jenkins, James Bunn, Alister G Craig, Virginie Terraube, Roger J S Preston, Cynthia Donkor, George E Grau, Jan A van Mourik, James S O'Donnell

“…These novel findings suggest that severe P. falciparum infection is associated with acute endothelial cell activation, abnormal circulating ULVWF multimers, and a significant reduction in plasma ADAMTS13 function which is mediated at least in part by an unidentified inhibitor.…”
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Age-related lung changes linked to altered lysosomal protease profile, histology, and ultrastructure. by Mohammed Aufy, Mahmoud Abd-Elkareem, Medina Mustafic, Mostafa A Abdel-Maksoud, Ali Hakamy, Veronika Baresova, Akram A Alfuraydi, Mahmoud Ashry, Jana Lubec, Ayman S Amer, Christian R Studenik, Ahmed M Hussein, Mohamed H Kotob

“…These alterations highlight potential mechanisms underlying age-associated changes in lung tissue integrity and provide insights into protease-mediated ECM remodeling in the context of aging lungs.…”
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Towards the Universal Health Coverage in Ghana: An exploratory, cross-sectional study on the National Health Insurance Scheme by Richard Boateng, Alfred E Yawson

“…Discussion and Conclusion: Findings of our study showed that perceived quality of healthcare services delivered by NHIS may play a certain role on the attainment of UHC both directly and by mediating effects of UHA and FRP. Therefore, good healthcare services provided by NHIS can promote universal healthcare access and financial risk protection as major catalysts towards the attainment of UHC in Ghana.…”
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Sakuranetin Prevents Acetaminophen-Induced Liver Injury via Nrf2-Induced Inhibition of Hepatocyte Ferroptosis by Long Z, Yu X, Li S, Cheng N, Huo C, Zhang X, Wang S

“…Serum transaminase levels, histological changes, inflammatory mediators, oxidative stress, ferroptosis-related markers and Nrf2 signaling pathway proteins were analyzed.Results: Sakuranetin significantly reduced serum alanine aminotransferase (ALT) and aspartate aminotransferase (AST), as well as inflammatory factor; increased HepG2 activity and decreased cell death; inhibited ROS production, increased glutathione (GSH) content, expression of Glutathione Peroxidase 4 (GPX4) and Solute Carrier Family 7 Member 11 (SLC7A11), and decreased malondialdehyde and Acyl-CoA Synthetase Long Chain Family Member 4 (ACSL4) expression in mice and HepG2 cells after APAP treatment. …”
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From green demand to deceptive practices: A cross-cultural study the impact of consumer green preferences on corporate greenwashing behavior in China, Republic of Korea, and Malays... by Zhibin Tao

“…Utilizing valid survey data from 1433 enterprises across these three countries, and employing SEM and fsQCA methods, the empirical test results indicate that among the three countries: (1) Consumer green preferences lead to corporate engagement in greenwashing behavior. (2) Consumer green preferences lead to market competitive pressure. (3) Market competitive pressure results in corporate greenwashing behavior. (4) Market competitive pressure plays a significant mediating role in the process by which consumer green preferences influence corporate greenwashing behavior. (5) Regulatory environment plays a moderating role in some of the impact paths across different countries, and in some impact paths, the moderating effect is absent. (6) The analysis results using the fsQCA method show that there are 4 different configurations leading to strong greenwashing behavior in enterprises in China, 3 in Republic of Korea, and 4 in Malaysia, and the most influential and explanatory configurations and paths have been identified. …”
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The PTP1B Inhibitor Trodusquemine (MSI-1436) Improves Glucose Uptake in Equine Metabolic Syndrome Affected Liver through Anti-Inflammatory and Antifibrotic Activity by Lynda Bourebaba, Anna Serwotka-Suszczak, Nabila Bourebaba, Magdalena Zyzak, Krzysztof Marycz

“…Interestingly, PTP1B inhibition ameliorated the expression of TIMP-1 and Smad7, both important antifibrotic mediators. Furthermore, application of MSI-1436 was found to augment the abundance of glycosylated Glut-2, which subsequently expanded the glucose absorption in the EMS liver, probably due to an enhanced Glut-2 stability and half-life onto the plasma cell membranes. …”
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The influences of environmental awareness on green performance by M.H. Mansour

“…To evaluate the model, Smart Partial Least Square was employed to conduct validity and reliability testing and develop structural equation modeling.FINDINGS: According to the results, Environmental awareness mediated the effects of green human resource management and green behaviours on green performance. …”
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Health data sharing in Germany: individual preconditions, trust and motives by Elias Kühnel, Felix Wilke

“…Trust plays a particularly important role here, as it acts as a mediator between individual preconditions and individual motives. …”
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Influence of allelic polymorphism in the 3’ untranslated region of the <i>StTCP23</i> gene on the tolerance of potato cultivars to the potato spindle tuber viroid by N. V. Mironenko, A. V. Kochetov, O. S. Afanasenko

“…It is known that the pathological phenotype of potato plants can be mediated by complementary interactions between the genomic RNA of PSTVd and mRNA of some regulatory genes, which consequently lead to RNA interference, the synthesis of small interfering RNAs (vd-sRNA PSTVd), and impaired morphogenesis. …”
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Navigating the medical journey: Insights into medical students' psychological wellbeing, coping, and personality. by Aisha Ali Hawsawi, Neil Nixon, Elena Nixon

“…Notably, problem-focused coping partially mediated the relationship between stress and depression. …”
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