Piezoelectric biosensor with dissipation monitoring enables the analysis of bacterial lytic agent activity by Radka Obořilová, Eliška Kučerová, Tibor Botka, Hana Vaisocherová-Lísalová, Petr Skládal, Zdeněk Farka

“…Furthermore, the dissipation signal analysis facilitated the precise real-time monitoring of phage-mediated lysis. Finally, the QCM-D biosensor was employed to evaluate the synergistic effect of subinhibitory concentrations of the antibiotic amoxicillin with the bacteriophage P68, enabling monitoring of the lysis of P68-resistant wild-type strain S. aureus RN4220. …”
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Enhanced effect of the immunosuppressive soluble HLA-G2 homodimer by site-specific PEGylation by Chisato Yamada, Kimiko Kuroki, Naoyoshi Maeda, Hiroshi Watanabe, Ami Takahashi, Katsumi Maenaka

“…Abstract Human leukocyte antigen (HLA)-G is a nonclassical HLA class I molecule that has an immunosuppressive effect mediated by binding to immune inhibitory leukocyte immunoglobulin-like receptors (LILR) B1 and LILRB2. …”
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Bee Venom—A Potential Complementary Medicine Candidate for SARS-CoV-2 Infections by Keneth Iceland, Kasozi, Simon Peter, Musinguzi

“…BV anti-inflammatory properties are associated with melittin and phospholipase A2 (PLA2), both of which show activity against enveloped and non-enveloped viruses, including H1N1 and HIV, with activity mediated through antagonist activity against interleukin-6 (IL-6), IL-8, interferon-g (IFN-g), and tumor necrosis factor-a (TNF-a). …”
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Neutrophils: From Inflammatory Bowel Disease to Colitis-Associated Colorectal Cancer by Chen T, Liu J, Hang R, Chen Q, Wang D

“…Neutrophils affect the pathophysiology of IBD through various mechanisms, including the production of reactive oxygen species (ROS), degranulation, the release of inflammatory mediators and chemokines, and the formation of neutrophil extracellular traps (NETs). …”
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Levels of IL-6 and IL-1β in Umbilical Cord Blood in Relation to Mode of Birth by Ebru Aslan Patlakoğlu, Sündüz Özlem ALTINKAYA, Mustafa Uğur, Cuma Taşın, Nezaket Kadıoğlu

“…CONCLUSION: In healthy and term pregnancies, the exposition of spontaneous vaginal delivery and labor is not associated with activation of inflammatory mediators compared to cesarean. The data of the present study did not support the increasing ratio of newborn complications (respiratory distress syndrome, bronchopulmonary dysplasia, the need for prolonged oxygen therapy and neonatal intensive care unit, allergic diseases of infancy period) after cesarean delivery due to inadequate increasing levels of cytokines in newborns delivered by cesarean. …”
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Changing of expression actinbinding proteins in the kidney under dehydration by I. I. Khegay

“…The most probable molecular mechanism of changing the expression of the genes for alpha-actinin and tropomyosin is transduction of the V2-mediated vasopressin hormonal signal to protein kinase A, phosphorylation of the cAMPresponsible transcriptional factor CREB, and nuclear CREB interaction with gene CRE sites sensitive to it.…”
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Examining alternative approaches to antibiotic utilisation: A critical evaluation of phage therapy and antimicrobial peptides combination as potential alternatives by Chibuzo Vincent Alisigwe, Chibuzor Stanley Ikpa, Uchenna Joseph Otuonye

“…The results indicated that pre-treatment with R8K significantly increased the susceptibility of S. aureus to Lys11-mediated lysis, even at low concentrations. While the precise mechanisms underlying the synergistic action of AMPs and bacteriophages remain unclear, our findings underscore the need for further research in this promising domain. …”
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An Indole Alkaloid Extracted from Evodia rutaecarpa Inhibits Colonic Motility of Rats In Vitro by Guo-xiang Wang, Yan-li Xiang, Hong-gang Wang, Yang-de Miu, Guang Yu

“…This study provides the first evidence that evodiamine can regulate colonic motility in rats by mediating calcium homeostasis in smooth muscle cells. …”
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Identification of crucial pathways and genes linked to endoplasmic reticulum stress in PCOS through combined bioinformatic analysis by Yan Zhang, Xiujuan Chen, Yuan Lin, Xiaoqing Liu, Xiumei Xiong

“…Our study revealed that these DEGs were primarily associated with cell cycle arrest, p53-mediated signal transduction, drug response, and gland development, with molecular functions enriched in growth factor binding, collagen binding, and receptor protein kinase activity. …”
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Incidence, Risk Factors, and Treatment Outcome of Acute Renal Allograft Rejection by Remyasri Akhil, Eby Mathew, Bipi Prasannan, Vishnu Dev Urs, V. Narayanan Unni

“…At 23.77 ± 24.6 months of follow-up, graft survival was 12/12 (100%) in those with early T-cell-mediated rejection (TCMR) compared to 5/9 (55.6%) with late acute TCMR (P = 0.01). …”
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Immunoinformatic strategy for developing multi-epitope subunit vaccine against Helicobacter pylori. by Md Nahian, Md Rasel Khan, Fabiha Rahman, Hossain Mohammed Reza, Imren Bayil, Tanjum Ahmed Nodee, Tabassum Basher, Mostafizur Rahaman Sany, Rabeya Najnin Munmun, S M Ariful Habib, Lincon Mazumder, Mrityunjoy Acharjee

“…Additionally, immune simulations showed elevated levels of cell-mediated immunity, while repeated exposure simulations indicated rapid antigen clearance. …”
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The age and residence impact on IgE serum level in patients with allergic asthma by Raghdah Maytham Hameed, Huda Hadi Al-Hasnawy, Haidar Abdul Amir Najim Abood

“…Abstract Background: Immunoglobulin E (IgE) has a role in mediating allergic reactions and their powerful effector functions, but numerous factors influence its value. …”
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Axial Spondyloarthritis in Black Americans: An Observational Study From Five Centers in Shelby County, Tennessee by Krishna Kommineni, Iman Abutineh, Cathy Chapman, Debendra Pattanaik, Mohamad Bittar

“…Objective Axial spondyloarthritis (axSpA) is an immune‐mediated disease that predominantly affects the axial skeleton. …”
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Magnitude of Psoriasis and Its Associated Factors, and Quality of Life of Psoriasis Patients among Patients Who Attend Dermatology Clinic at Tibebe Ghion Comprehensive Specialized... by Wosen Ketema, Solomon Ketema Bogale, Eyob Ketema Bogale

“…Psoriasis is a common immune-mediated papulosquamous inflammatory skin disease characterized by well-demarcated, erythematous silvery scaly plaques. …”
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HIF-3α-Induced miR-630 Expression Promotes Cancer Hallmarks in Cervical Cancer Cells by Forming a Positive Feedback Loop by Qiaohui Gao, Zhenghua Ren, Shengyuan Jiao, Juan Guo, Xia Miao, Jin Wang, Junye Liu

“…Consequently, stable overexpression of miR-630 in HeLa cells promotes cancer hallmarks, including radioresistance, inhibition of apoptosis, increased migration and invasion, and EMT-mediated metastasis. Meanwhile, inhibition of miR-630 showed opposite features. …”
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Time Course of Brain Activity Changes Related to Number (Quantity) Processing Triggered by Digits Versus Number Words: An Event-Related Potential (ERP) Study by Peter Walla, Philipp Klimovic

“…Furthermore, it can be concluded that digits are better symbols for mediating quantity processing in the human brain than number words.…”
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MUC5B regulates alterations in the immune microenvironment in nasopharyngeal carcinoma via the Wnt/β-catenin signaling pathway by Hongming Wang

“…Conclusions Mucin 5B, oligomeric mucus/gel-forming regulates the immune escape of nasopharyngeal carcinoma cells and participates in tumor progression by mediating the Wnt/β-catenin signaling pathway.…”
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CSE-8, a filamentous fungus-specific Shr3-like chaperone, facilitates endoplasmic reticulum exit of chitin synthase CHS-3 (class I) in Neurospora crassa by Samantha Verónica González-Téllez, Meritxell Riquelme

“…The current evidence suggests that the biogenesis of CHS exclusive to filamentous fungi may involve pathways independent of CSE-mediated receptors.…”
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Rabies epidemiology, prevention and control in Nigeria: Scoping progress towards elimination. by Philip P Mshelbwala, J Scott Weese, Olufunmilayo A Sanni-Adeniyi, Shovon Chakma, Stephen S Okeme, Abdullah A Mamun, Charles E Rupprecht, R J Soares Magalhaes

“…<h4>Conclusion</h4>Significant improvements are necessary to achieve the elimination of human rabies mediated via dogs by 2030.…”
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An exacerbated phosphate starvation response triggers Mycobacterium tuberculosis glycerol utilization at acidic pH by Claire Healy, Sabine Ehrt, Alexandre Gouzy

“…Our data further support the role of limited glycerol uptake and ROS-mediated glyceraldehyde-3-phosphate dehydrogenase (GAPDH) inhibition in causing Mtb acid growth arrest. …”
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