Serum lipids mediate the association of per- and polyfluoroalkyl substances exposure and age-related macular degeneration. by Xiaodong Chen, Jiaqi Li, Ningda Xu, Xuewei Li, Jiarui Li, Qianwen Guo, Jia Zhang, Heng Miao, Lvzhen Huang

“…ORHDL, 1.028; 95% CI, 1.014 to 1.042; P<0.001), and mediated the relationship of PFOS exposure and AMD risk, with mediation proportions of 5.73% (P = 0.020) and 7.27% (P = 0.032), respectively.…”
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Influence of personality trait on business performance: The mediating role of risk aversion in hybrid tourism entrepreneurs by Shahnawaz Ahmad Dar, Neda Ul Bashir

“…In addition, risk aversion partially mediates the association between personality traits and business performance. …”
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Warming-driven migration of enterotypes mediates host health and disease statuses in ectotherm Litopenaeus vannamei by Shenzheng Zeng, Zhijian Huang, Satapornvanit Kriengkrai, Renjun Zhou, Derun Yuan, Nguyễn Văn Tuấn, Zhiming Zhu, Luwei Zheng, Qilu Hou, Xuanting Li, Qi Chen, Lingyu Zhang, Dongwei Hou, Zhixuan Deng, Shicheng Bao, Wenjun Wang, Sukontorn Khoruamkid, Soo Loon Goh, Shaoping Weng, Jianguo He

“…Collectively, the warming-driven enterotypes mediated shrimp health, which exemplified the causal relationship between temperature rising and ectothermic animals’ health. …”
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Proximal tubular RAGE mediated the renal fibrosis in UUO model mice via upregulation of autophagy by Bohao Liu, Tianshi Sun, Huiling Li, Shuangfa Qiu, Yijian Li, Dongshan Zhang

“…Mechanistically, RAGE mediated TGF-β1-induced phosphorylation of Stat3 and directly upregulated the Atg7 to increase the level of autophagy, and ultimately resulting in renal fibrosis. …”
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The mediating effects of perceived usefulness and perceived ease of use on nurses’ intentions to adopt advanced technology by Abid Hussain, Ma Zhiqiang, Mingxing Li, Arif Jameel, Shahida Kanwel, Saif Ahmad, Bailin Ge

“…The study examines the intention to use technology through the mediating effects of perceived usefulness and perceived ease of use, with technology sophistication. …”
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The educational potential of collaborative writing mediated by digital technology in times of pandemic: a scoping review by Liverano Giuseppe

“…The aim of this contribution is to highlight the most effective technology-mediated collaborative writing interventions that have been implemented during the Covid-19 pandemic. …”
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The Mediating Effect of Social Emotional Learning between Relationship on Basic Psychological Needs and Technology Addiction by Murat Agirkan

“…The study also examined whether there is a mediating effect of SEL in the relationship between basic psychological needs and technology addiction. …”
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Age modulates, religious coping mediates: the role of attitude to self in cancer patients’ quality of life by Maria-Chidi C. Onyedibe, Runcie C.W. Chidebe, Runcie C.W. Chidebe, Runcie C.W. Chidebe, Barbara L. Andersen, Uzoamaka F. Ugwoke, Lawrence Ejike Ugwu, Lawrence Ejike Ugwu

“…Negative religious coping (NRC) mediated the relationships between ATS and HRQoL, amplifying negative effects on physical (β = −0.25, p &lt; 0.001) and functional well-being (β = −0.32, p &lt; 0.001). …”
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The effect of prosocial behaviour manageability on conscious awareness in university athletes: The mediating role of athlete identity by Unal Saki, Mehmet Oztas

“…The results of this study show that athlete identity plays an important mediating role in the effect of prosocial behaviors on mindfulness. …”
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Jiangzhi Granule Ameliorates JNK-Mediated Mitochondrial Dysfunction to Reduce Lipotoxic Liver Injury in NASH by Jiang Y, Xu J, Ding J, Liu T, Liu Y, Huang P, Wang Q, Zheng P, Song H, Yang L

“…This study aims to investigate the pharmacological mechanism of Jiangzhi Granule (JZG), a Chinese herbal formula against NASH, with a focus on its regulation of JNK signaling-mediated mitochondrial function.Methods: Hepatocytes were induced by palmitic acid (PA) for 24 h to establish an in vitro lipotoxic model, which was simultaneously treated with either JZG or vehicle control. …”
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The Use of Antisense-Mediated Inhibition to Delineate The Role of Inflammatory Agents in The Pathophysiology of Spinal Cord Injury by Damien D. Pearse, Francisco C. Pereira, Katina Chatzipanteli, Francisco W. Dalton Dietrich, Mary Bartlett Bunge

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Variational graph autoencoder for reconstructed transcriptomic data associated with NLRP3 mediated pyroptosis in periodontitis by Pradeep K. Yadalam, Prabhu Manickam Natarajan, Carlos M. Ardila

“…Abstract The NLRP3 inflammasome, regulated by TLR4, plays a pivotal role in periodontitis by mediating inflammatory cytokine release and bone loss induced by Porphyromonas gingivalis. …”
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Brand Love Mediates Fashion Innovativeness, Perceived Quality, Value for Money, and Word of Mouth Effects by Ida Bagus Putu Wahyadyatmika, Luh Putu Mahyuni

“…The revised text is as follows: (2) The formulation of the research problem is to examine whether Fashion Innovativeness, Perceived Quality, Value for Money, and Word of Mouth have an influence on Brand Love and Brand Loyalty, and to analyze whether Brand Love serves as a mediating factor in the relationship between these variables and Brand Loyalty. (3) The purpose of this research is to determine the impact of Fashion Innovativeness, Perceived Quality, Value for Money, and Word of Mouth on Brand Love and Brand Loyalty, as well as to evaluate the mediating role of Brand Love in influencing Brand Loyalty. (4) This research was conducted in the city Denpasar with a total of 150 respondents, data collection was carried out through questionnaires and analyzed using SEM for mediation tests. (5) The research reveals that Fashion Innovativeness and Value for Money have limited impact on Brand Love and Brand Loyalty, with the latter showing a negative effect. …”
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Sotorasib resistance triggers epithelial-mesenchymal transition and activates AKT and P38-mediated signaling by Raquel Arantes Megid, Guilherme Gomes Ribeiro, Izabela Natalia Faria Gomes, Ana Carolina Laus, Letícia Ferro Leal, Letícia Ferro Leal, Luciane Sussuchi da Silva, Abu-Bakr Adetayo Ariwoola, Josiane Mourão Dias, Rui Manuel Reis, Rui Manuel Reis, Renato Jose da Silva-Oliveira, Renato Jose da Silva-Oliveira

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The Mediating Effect of Self-Efficacy on the Relationship Between Entrepreneurship Education and Entrepreneurial Intentions of University Students by Jacob L. Oyugi

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Multifunctional nanoparticles confers both multiple inflammatory mediators scavenging and macrophage polarization for sepsis therapy by Wenjie Xi, Weijie Wu, Lili Zhou, Qi Zhang, Shushu Yang, Lihong Huang, Yijun Lu, Jing Wang, Xinjin Chi, Yang Kang

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Inactivity‐mediated molecular adaptations: Insights from a preclinical model of physical activity reduction by Alice Meyer, Nicole Kim, Melissa Nguyen, Monica Misch, Kevin Marmo, Jacob Dowd, Christian Will, Milica Janosevic, Erin J. Stephenson

“…These adaptations manifest during the early stages of physical inactivity, even when energy balance is maintained, suggesting that inactivity‐mediated metabolic reprogramming is an early event that precedes changes in body composition. …”
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Pulmonary Remodeling in Equine Asthma: What Do We Know about Mediators of Inflammation in the Horse? by Ann Kristin Barton, Heidrun Gehlen

“…Mediators of Inflammation…”
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The Mediating Role of Organizational Citizenship Behavior (OCB) on Employee Performance: Locus of Control and Self-Efficacy by Amirul Syah, Safrida Safrida

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Oridonin Relieves Angiotensin II-Induced Cardiac Remodeling via Inhibiting GSDMD-Mediated Inflammation by Shuang Lin, Shanshan Dai, Jiahui Lin, Xiaohe Liang, Weiqi Wang, Weijian Huang, Bozhi Ye, Xia Hong

“…These results suggest that oridonin is proved to be a potential protective drug against GSDMD-mediated inflammation and myocardial remodeling.…”
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