Developing “You’re History, Pal!”: Employing Role-Playing Games as Pedagogical Instruments by Ștefana Iosif

“…As such, through a variety of role playing games, the students essentially take over the classroom, with the instructor’s main objective being to guide and mediate, removing their traditional teaching hat. …”
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The moderating effects of physical activity on social anxiety and sleep disturbance: managing gaming disorder in young e-sports players by Serdar Solmaz, Mehmet İnan, Mustafa Yaşar Şahin

“…This study aims to examine the potential relationship between IGD, social anxiety, and insomnia, investigate the mediating role of social anxiety in this relationship, and explore the moderating role of physical activity in alleviating the negative effects of IGD.MethodsThe study involved 475 adolescent and young e-sports players aged 14–24, who typically engage in an average of 6 h of gaming per day. …”
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Applying Educational Programming Language-Based Learning to Enhance the Programming Skills of Non-ICT Engineering College Students by Jorge Rodas-Silva, Jorge Parraga-Alava, Mariuxi Vinueza-Morales, Ana Eva Chacón Luna, Jesennia Cárdenas-Cobo

“…The study results showed that students who received EPL-mediated learning with App Lab had significant increase in their programming skills. …”
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The effects of fluid resuscitation on the hemodynamic parameters of experimental induced endotoxemia in the neonatal calves by Enes Akyüz, Alparslan Coşkun, İsmail Şen

“…<p><strong>Aim:</strong> Endototoxin is known to be an important mediator of gram negative bacterial sepsis. Endotoxemia is associated with high mortality rates in neonatal calves. …”
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Therapeutic Implications of a Polymethoxylated Flavone, Tangeretin, in the Management of Cancer via Modulation of Different Molecular Pathways by El-Shaimaa A. Arafa, Noura T. Shurrab, Manal A. Buabeid

“…Furthermore, tangeretin works through mitigating levels of inflammatory mediators in the immune system. Using tangeretin in combination with clinically applied anticancer drugs could be a good strategy for increasing the efficiency of these agents and protecting noncancerous cells from damage caused by chemotherapy. …”
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The effect of liquidity risk, capital and third-party fund on bank performance with credit risk as intervening variable: Cases in conventional Bank in Indonesia by Sutrisno Sutrisno

“…Practical implications – It is hoped this research can be used by bank management in its efforts to increase profitability by considering four variables that influence it and shows the role of credit risk in mediating the influence of independent variables on profitability. …”
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Enhancing Mesenchymal Stromal Cell Immunomodulation for Treating Conditions Influenced by the Immune System by Bella S. Guerrouahen, Heba Sidahmed, Asma Al Sulaiti, Moza Al Khulaifi, Chiara Cugno

“…The precise mechanism by which MSCs affect functions of most immune effector cells is not completely understood but involves direct contact with immune cells, soluble mediators, and local microenvironmental factors. Recently, it has been shown that their homeostatic resting state requires activation, which can be achieved in vitro with various cytokines, including interferon-γ. …”
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Efficacy and safety of dual-targeted therapy for inflammatory bowel disease: a retrospective multicenter study in China by Xiuxiu Jin, Kefang Sun, Liying Wang, Haiyan Shen, Dan Ma, Tejia Shen, Chunxiao Chen, Lan Li

“…Objective: This study aimed to examine the efficacy and safety of combining biologics or small molecules in patients with refractory IBD, active EIM, or active immune-mediated inflammatory disease (IMID). Design: This was a retrospective and multicenter study. …”
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Prevalence of direct antiglobulin test positive in whole blood donors: Study at a tertiary blood center Northern India by Jyoti Bharti, Archana Solanki, Ashutosh Singh, Mallika Agarwal, Tulika Chandra

“…Rarely, DAT is positive in nonimmune-mediated hemolytic anemias as well. Standard donor screening techniques do not require the DAT to be performed. …”
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Microalgae-based bioremediation of refractory pollutants: an approach towards environmental sustainability by Mostafa M. El-Sheekh, Hala Y. El-Kassas, Sameh S. Ali

“…Microalgal biomass can mediate contaminated wastewater effectively through accumulation, adsorption, and metabolism. …”
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Upregulation of PGC-1α Attenuates Oxygen-Glucose Deprivation-Induced Hippocampal Neuronal Injury by Bin Han, Hui Zhao, Xingji Gong, Jinping Sun, Song Chi, Tao Liu, Anmu Xie

“…ChIP-Seq analysis was employed to discover the underlying molecular mechanism of PGC-1α-mediated neuroprotective effects. Our results showed that mitochondrial membrane potentials were increased and ROS production was decreased in PGC-1α overexpressing cells, which increased cell viability. …”
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Augmenter of Liver Regeneration (ALR) Protects Kidney from Ischemia/Reperfusion (I/R) Injury via Regulation of TLR4/MAPK Signaling Pathway by Ying Li, Yanying Xiong, Huihui Li, Yan Luo, Ling Zhang, Qin Zhang, Weijian Xiong, Haitao Tu

“…Toll-like receptor 4 (TLR4) can mediate innate activation and inflammation, and it is typically expressed within the ischemic kidney. …”
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RELIGIOUS COMMUNICATION IN THE CONTEXT OF CULTURE MEDIA by Maria S. Petrushkevych

“…Phenomena, that reflects the dramatic changes in the communicative environment are: mediatization of body and mind, the new practice of processing / reading information, the phenomenon of simultaneous perception of a large number of information channels – similar or different. …”
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Is Nuclear Anarchy Sustainable? A Temporal Approach by Ye. I. Uchaev, A. A. Kvartalnov

“…However, the debate, as it stands now, ignores the fact that both technology and social structures are embedded in – and mediated by – cultures and worldviews. In particular, both nuclear weapons and interstate anarchy are embedded in specific temporalities.Taking this fact into account, we identify and compare perceptions of time that are interrelated with nuclear weapons, on one hand, and international anarchy, on the other. …”
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Predicting microRNA target genes using pan-cancer correlation patterns by Shuting Lin, Peng Qiu

“…Together, this analysis revealed a novel framework for uncovering previously unidentified miRNA-gene relationships, enhancing the collective comprehension of miRNA-mediated gene regulation.…”
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Association of loneliness with the risk of pain in older Chinese adults by Aijun Song, Siying Yu, Yao Shen, Zongyan Guo, Jian Shi

“…Abstract This study investigates the long-term effects of loneliness on pain experiences in older Chinese adults, focusing on the mediating role of depression. Data from the China Health and Retirement Longitudinal Study (2013–2020) included 1,592 participants aged 60 and above. …”
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LysR-Type Transcriptional Regulator VirR Responds to Temperature and pH and Directly Activates the Transcription of virS-Containing Operon in Rhodococcus equi by Tsutomu Kakuda, Takashi Sato, Mari Takuhara, Hirofumi Hagiuda, Yasunori Suzuki

“…Furthermore, the regulation of VapA expression in response to temperature and pH is mediated by VirR.…”
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Influence of Kinship on Family Stability in Kagunga Sub-County Rukungiri District. by Mugarura, Junior

“…Both older and younger respondents recognize the importance of these relationships in providing emotional support, sharing resources, and mediating conflicts. Kinship networks contribute significantly to the well-being of family members by offering a support system that helps stabilize the family unit during times of need. …”
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Effects of B-Blockers on the Sympathetic and Cytokines Storms in Covid-19. by Al-kuraishy, Hayder M., Al-Gareeb, Ali Ismail, Mostafa-Hedeab, Gomaa, Keneth Iceland, Kasozi, Zirintunda, Gerald, Aslam, Akhmed, Allahyani, Mamdouh, Welburn, Susan Christina, Batiha, Gaber El-Saber

“…In conclusion, b-blockers interrupt this interaction through inhibition of several mediators of CS and SS with prevention development of neural-cytokine loop in SARS-CoV-2 infection. …”
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Photodynamic and photothermal bacteria targeting nanosystems for synergistically combating bacteria and biofilms by Xiao Wang, Wenxuan Shi, Yu Jin, Zhuoyuan Li, Tanjun Deng, Tingshu Su, Ao Zheng, Lingyan Cao

“…Upon exposure to red-light (RL) irradiation, Ce6@ZIF-8-PDA/UBI showed excellent antibacterial effect on S. aureus, E. coli, F. nucleatum, and P. gingivalis and exceptional light-driven antibiofilm activity to P. gingivalis biofilm, which was a result of the efficient bacterial localization mediated by PDA/UBI, as well as the PDT/PTT facilitated by Ce6/PDA interactions. …”
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