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9621
Soil Respiration Variations in Temperate Rhododendron (Rhododendron arboreum) Forest of Annapurna Conservation Area (ACA) in Nepal
Published 2022-01-01“…And the variation in SR was mediated by a short-range (2-3°C) of ST difference in the month of October during autumn season. …”
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9622
Endothelial Function in Women with and without a History of Glucose Intolerance in Pregnancy
Published 2013-01-01“…Endothelial dysfunction, as indicated by impaired flow-mediated dilatation (FMD) on brachial artery ultrasound, is an early marker of vascular disease. …”
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9623
Influence of leptin administration to pregnant female mice on obesity development, taste preferences, and gene expression in the liver and muscles of their male and female offsprin...
Published 2021-10-01“…An increase in blood leptin level in pregnant females reduces the risk of obesity and insulin resistance in the offspring, although the mechanisms mediating this effect are unknown. Neither is it known whether maternal leptin affects taste preferences. …”
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9624
Is polymyositis a rare or over-diagnosed entity? A descriptive follow-up study of patients initially admitted in a tertiary center with the diagnosis of polymyositis
Published 2020-01-01“…During a median follow-up period of 4.0 years and constant diagnostic reinvestigation, only 30 (27.7%) out of the 108 participants maintained the PM diagnosis, whereas the other patients were re-diagnosed with immune-mediated necrotizing myopathy (20.4%), inclusion body myositis (18.5%), muscular dystrophy 13.0% as (13.0%), antisynthetase syndrome (8.3%), metabolic myopathies (5.6%), and other muscle diseases (7.3%). …”
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9625
Movement disorders in autoimmune encephalitis: Clinical spectrum, prognosis, and outcomes from an Indian cohort
Published 2024-12-01“…BACKGROUND: Antibody-mediated autoimmune encephalitis (AE) encompasses inflammatory central nervous system disorders linked etiologically with neuronal autoantibodies. …”
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9626
Optogenetic screening of MCT1 activity implicates a cluster of non-steroidal anti-inflammatory drugs (NSAIDs) as inhibitors of lactate transport.
Published 2024-01-01“…However, current drugs targeting either MCT1 or MCT4, which traditionally mediate lactate import or efflux respectively, show limited efficacy beyond in vitro models. …”
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9627
State tax policy in Ukraine: historical and legal aspect (based on the example of the XX century)
Published 2020-06-01“…However, discrepancy of the made tax decisions, which took root on general level, turned out to be consequence strengthening of planned methods and mediate in administrative control, which constantly amplified arbitrariness from the state. …”
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9628
Discourse of University: Knowledge in the Era of Contemporary Forms of Capitalism Development
Published 2021-04-01“…It is shown that the predominance of one or another tendency depends on university’s discourse functioning which serves as a mediator between a subject of knowledge and the capitalism discourse. …”
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9629
The human‐specific noncoding RNA RP11‐424G14.1 functions at the intersection of sexually dimorphic pathways in inflammation, senescence, and metabolism
Published 2025-02-01“…Conversely, in female keratinocytes, IGFBP3 is the top gene repressed by the X‐linked long noncoding RNA XIST, suggesting a central role of IGFBP3 in mediating sexual dimorphism. Knockdown of RP11‐424G14.1 or IGFBP3 in male keratinocytes inhibits cellular senescence, consistent with increased longevity in females. …”
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9630
The link between spreading depolarization and innate immunity in the central nervous system
Published 2025-02-01“…Research has established a clear link between SD and the activation of pro-inflammatory pathways, particularly through the release of cytokines like interleukin-1β and tumor necrosis factor-α, and the involvement of inflammatory mediators such as cyclooxygenase-2 and high mobility group box 1 (HMGB1). …”
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9631
Kounis Syndrome Secondary to Medicine-Induced Hypersensitivity
Published 2021-01-01“…Kounis syndrome is the concurrence of an acute coronary syndrome (ACS) caused by coronary vasospasms, acute myocardial infarctions, or stent thromboses in case of allergic or hypersensitivity reactions. Kounis syndrome is mediated by mast cells that interact with macrophages and T-lymphocytes, causing degranulation and inflammation with cytokine release. …”
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9632
Generality of toxins in defensive symbiosis: Ribosome-inactivating proteins and defense against parasitic wasps in Drosophila.
Published 2017-07-01“…Here we test the generality of RIP-mediated protection by examining whether Spiroplasma RIPs also play a role in wasp protection, in D. melanogaster and D. neotestacea. …”
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9633
Posttranscriptional Suppression of Lipopolysaccharide-Stimulated Inflammatory Responses by Macrophages in Middle-Aged Mice: A Possible Role for Eukaryotic Initiation Factor 2α
Published 2014-01-01“…Given that a reduced rate of protein synthesis is a common age-related biochemical change, which is partially mediated by increased phosphorylation of eukaryotic initiation factor-2α (eIF-2α), we investigated the mechanism responsible for the deterioration of macrophage inflammatory responses, focusing specifically on the age-related biochemical changes in middle-aged mice. …”
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9634
MiR-223 within neutrophil axis promotes Th17 expansion by PI3K-AKT pathway in systemic lupus erythematosus
Published 2025-02-01“…Finally, we elucidated that neutrophils potentiate the induction of Th17 through the activation of thePI3K-AKT pathway mediated by miR-223 during SLE-associated Th17 expansion. …”
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9635
Affective and social pain modulation in children-Experimental evidence using picture viewing.
Published 2024-01-01“…The correlation between children's tendency to catastrophize and pain relief by mothers' faces was mediated by induced arousal, likely reflecting the degree of motivational activation of seeking social support.…”
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9636
Mechanisms of Cancer-Induced Bone Pain
Published 2025-01-01“…When tumor cells produce inflammatory mediators that acidify the microenvironment or damage nerve endings, the spinal cord becomes excessively stimulated, resulting in increased or prolonged pain signals that propagate to the higher central nervous system through the ascending pathway. …”
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9637
PET imaging of AAV9 and AAVBR1 trafficking in normal mice
Published 2025-02-01“…Abstract Adeno-associated virus (AAV) mediated gene therapy is advancing and needs a noninvasive imaging tool to evaluate its effective targeting, biodistribution and clearance for precise use in humans. …”
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9638
Clinical Features in Aromatic L-Amino Acid Decarboxylase (AADC) Deficiency: A Systematic Review
Published 2022-01-01“…Adeno-associated viral vector-mediated gene transfer of the human AADC gene into the putamina has become available. …”
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9639
Nitroxyl protects H9C2 cells from H/R-induced damage and inhibits autophagy via PI3K/Akt/mTOR pathway.
Published 2025-01-01“…Further experiments demonstrated that the effects of HNO were mediated through upregulation of PI3K/Akt/mTOR pathway. …”
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9640
2′-Fucosyllactose as a prebiotic modulates the probiotic responses of Bifidobacterium bifidum
Published 2025-01-01“…The growth inhibition of 2′-FL on the Cronobacter strains was mediated by promoting the secretion of antibacterial substances from B. bifidum. …”
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