The unified theory of acceptance and use of DingTalk for educational purposes in China: an extended structural equation model by Yukun Hou, Zhonggen Yu

“…The findings indicated that (1) effort expectancy (EE), performance expectancy (PE), facilitating conditions (FC), self-efficacy (SE), and received feedback (RF) could significantly impact users’ attitudes toward behavior (ATB); (2) social influence (SI), FC, RF, and ATB could be significant predictors of user behavioral intention (BI); (3) FC, RF, and BI were found to have a significant effect on use behavior (UB); (4) the extended UTAUT model could explain 60.9% of the variance of users’ behavioral intention of DingTalk in China; (5) the study identified ATB and BI as joint mediators between certain variables in the model. The study presented a robust theoretical underpinning to explain the acceptance and use of educational technologies in China and provided insights into the future enhancement of E-learning platforms.…”
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Rethinking Urban Greening: Implications of Crime Prevention Through Environmental Design for Enhancing Perceived Safety in Baitashan Park, Lanzhou by Fei Hou, Massoomeh Hedayati Marzbali, Mohammad Javad Maghsoodi Tilaki, Aldrin Abdullah

“…Our findings reveal that interpersonal needs significantly mediate the impact of CPTED on perceived safety, with SES playing a moderating role in both the direct and indirect effects. …”
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SDG-enabled decarbonisation transport pathways for mid-sized Indian cities by Darshini Mahadevia, Saumya Lathia, Chandrima Mukhopadhyay

“…This paper argues that (1) climate mitigation measures in countries like India – with rising income inequality and high social diversity in caste, religion and region – need a tailored assessment approach, (2) carefully mediating climate mitigation measures – like deep decarbonisation – at the local level is crucial to enable transformative change required to meet the Paris Agreement and the UN Agenda 2030, (3) enabling ‘just’ deep decarbonisation or SDG-enabled decarbonisation at the local level requires addressing unmet needs of the vulnerable population even at the cost of increased emissions, and (4) sector-specific decarbonisation strategies at the national level must be translated into the local area’s social, economic, environmental and institutional realities. …”
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The role of green finance in reshaping end-use energy consumption: insights from regional evidence in China by Mingzheng Deng, Xiangyi Lu, Ruibin Tong, Yan Xue, Shuaihang Shi, Rui Guo

“…Stronger impacts are observed in eastern regions due to mature financial infrastructures, whereas central and western regions experience comparatively weaker outcomes.DiscussionContrary to expectations, mediating factors such as industrial structure, energy efficiency, and green innovation have limited explanatory power for the observed impacts. …”
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Conducting polymer-based electrochemical sensors: Progress, challenges, and future perspectives by Aashutosh Dube, Shweta J. Malode, Abdullah N. Alodhayb, Kunal Mondal, Nagaraj P. Shetti

“…Incorporation of redox mediators, use of conducting hydrogels, and molecular imprinting are promising strategies for better performance of the derived sensor. …”
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Maternal and Fetal Lipid and Adipokine Profiles and Their Association with Obesity by Mario Solis-Paredes, Salvador Espino y Sosa, Guadalupe Estrada-Gutierrez, Sonia Nava-Salazar, Veronica Ortega-Castillo, Mario Rodriguez-Bosch, Eyerahi Bravo-Flores, Aurora Espejel-Nuñez, Maricruz Tolentino-Dolores, Rubí Gaona-Estudillo, Nancy Martinez-Bautista, Otilia Perichart-Perera

“…Excessive maternal weight gain during pregnancy may exert an effect over metabolic mediators in both mother and newborn.…”
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CNS resident macrophages exhibit region-specific states and immunogenic responses during Rbpj-deficient brain arteriovenous malformation by Sera Nakisli, Kayleigh Fanelli, Julia LaComb, Lily J. Arnold, Corinne M. Nielsen

“…Here, we used a mouse model of brain arteriovenous malformation (bAVM)—mediated by endothelial loss of Recombination signal binding protein for immunoglobulin kappa J region (Rbpj)—to investigate changes to brain resident macrophage states during neurovascular disease pathogenesis. …”
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CPK1 activates CNGCs through phosphorylation for Ca2+ signaling to promote root hair growth in Arabidopsis by Meijun Zhu, Bo-Ya Du, Yan-Qiu Tan, Yang Yang, Yang Zhang, Yong-Fei Wang

“…Abstract Cyclic nucleotide-gated channel 5 (CNGC5), CNGC6, and CNGC9 (CNGC5/6/9 for simplicity) control Arabidopsis root hair (RH) growth by mediating the influx of external Ca2+ to establish and maintain a sharp cytosolic Ca2+ gradient at RH tips. …”
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The Role of Mitochondrial NADPH-Dependent Isocitrate Dehydrogenase in Cancer Cells by Katarína Smolková, Petr Ježek

“…In highly respiring cells, the resulting NAD+ accumulation then induces sirtuin-3-mediated activating IDH2 deacetylation, thus increasing its protective function. …”
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Promotion of beta cell proliferation through DYRK kinase inhibition using the marine natural product breitfussin C by Sara Ullsten, Kine Østnes Hansen, Guillaume Axel Petit, Espen Holst Hansen, Jeanette Hammer Andersen

“…These results suggest that BfC mediates beta cell-protective effect by promoting proliferation through DYRK inhibition, highlighting its potential as a molecular starting point for the development of a therapeutic agent against diabetes.…”
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Identification of dequalinium as a potent inhibitor of human organic cation transporter 2 by machine learning based QSAR model by Fumihiro Yamane, Kenji Ikemura, Masayoshi Kondo, Manami Ueno, Masahiro Okuda

“…Moreover, dequalinium inhibited hOCT2-mediated transport of platinum anti-cancer agents (cisplatin and oxaliplatin) in a concentration-dependent manner. …”
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Interspecific potato hybrids as donors of durable resistance to pathogens by E. V. Rogozina, E. E. Khavkin

“…To overcome incompatibility in crosses, breeders employ ploidy manipulation in the parental forms, bridge crosses, the mediator method and various in vitro technologies. …”
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Autologous Cytokine-Induced Killer Cell Immunotherapy Enhances Chemotherapy Efficacy against Multidrug-Resistant Tuberculosis by Peijun Tang, Xingnian Chen, Junchi Xu, Yunlong Hu, Zhijian Ye, Xiafang Wang, Yumei Xiao, Xinghua Shen, Jianping Zhang, Yanjun Feng, Cuilin Shi, Xin Yu, Lixian Yi, Xinchun Chen, Binfeng Lu, Ping Xu, Zhongwen Sun, Meiying Wu

“…Multidrug-resistant tuberculosis (MDR-TB) causes persistent infection and challenges tuberculosis control worldwide. T cell-mediated immunity plays a critical role in controlling Mycobacterium tuberculosis (Mtb) infection, and therefore, enhancing Mtb-specific T cell immune responses represents a promising therapeutic strategy against TB. …”
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The Role of Parent-child Relationship in Parental Financial Teaching and Financial Behaviour of Students by Xolile Antoni

“…Furthermore, parental financial teaching mediates the role of the parent-child relationship on financial behaviour. …”
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Foxtail millet supplementation improves glucose metabolism and gut microbiota in rats with high-fat diet/streptozotocin-induced diabetes by Xin Ren, Linxuan Wang, Zenglong Chen, Min Zhang, Dianzhi Hou, Yong Xue, Xianmin Diao, Ruihai Liu, Qun Shen

“…In addition, 4 weeks of 48% FM supplementation siginificantly increased the relative abundance of Bifidobacterium and concentration of butyrate, suggesting that the hypoglycemic effects of FM supplementation might be partially mediated by gut microbiota. Collectively, we found a dose-dependent relationship between FM supplementation and improvement of blood glucose metabolism, but did not find a synergistic effect between FM supplementation and metformin (Met) treatment. …”
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RITUXIMAB VERSUS SPLENECTOMY IN CHRONIC PRIMARY ITP: EXPERIENCE OF A SINGLE HEMATOLOGY CLINIC by Rawanda Shamoon, Ahmed Khudair Yassin, Sarah Laith Alnuaimi

“… Objective: Immune thrombocytopenia (ITP) is an acquired immune-mediated disease that lacks an underlying etiology. …”
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Unveiling the role of knowledge management effectiveness in university's performance through administrative departments’ innovation by Abu Elnasr E. Sobaih, Hassane Gharbi, Mohamed A. Ben Abdallah, Osama H. Mahmoud Hassan

“…Furthermore, the results suggest that departments’ innovation acts as a mediator in the link between knowledge management effectiveness and performance of KFU (β= 0.129, with p = 0.021 <0.05). …”
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A RESEARCH ON SOCIAL MEDIA ADDICTION AND DOPAMINE DRIVEN FEEDBACK by Gamze Macit, Hüseyin Bilal Macit, Orhan Güngör

“…Everyone in society has got the chance to become mediatic and famous, and many of them have started to make an effort for it. …”
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Decursinol angelate relieves inflammatory bowel disease by inhibiting the ROS/TXNIP/NLRP3 pathway and pyroptosis by Yudi Wang, Yudi Wang, Jiamin Wang, Yonghu Chen, Xuezheng Li, Xuezheng Li, Zhe Jiang, Zhe Jiang

“…Molecular docking technique and co-immunoprecipitation (Co-IP) method assay were applied to evaluate the targeting effect of DA on NLRP3 proteins, and MCC950, a specific inhibitor of NLRP3, was used as a positive control for validation.ResultsOur research indicates that DA’s distinctive molecular mechanism could entail binding to the NLRP3 protein, thereby suppressing the activation of the NLRP3 pathway and diminishing the assembly and activation of the NLRP3 inflammasome, thus functioning as an anti-inflammatory agent.ConclusionDA may play a role in improving BD by inhibiting the activation of the ROS/TXNIP/NLRP3 signaling pathway and the release of inflammatory mediators, and by repairing the intestinal barrier function.…”
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Chemical Identification and Antioxidant Screening of Bufei Yishen Formula using an Offline DPPH Ultrahigh-Performance Liquid Chromatography Q-Extractive Orbitrap MS/MS by Jinyan Wu, Bangrong Cai, Ang Zhang, Peng Zhao, Yan Du, Xuefang Liu, Di Zhao, Liu Yang, Xinguang Liu, Jiansheng Li

“…Numerous clinical trials have confirmed that Bufei Yishen formula (BYF), an herbal medicine, can alleviate the symptoms of COPD by reducing oxidative stress-mediated inflammation. However, the active components of BYF remain unclear. …”
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