The Rare Case of a Probably True IgE-Mediated Allergy to Local Anaesthetics by Christina Fellinger, Felix Wantke, Wolfgang Hemmer, Gabriele Sesztak-Greinecker, Stefan Wöhrl

“…In order to rule out the exceptional case of a true IgE-mediated reaction, allergy testing with local anaesthetics is still required in the workup of patients.…”
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The mediating role of social support in self-management and quality of life in patients with liver cirrhosis by Ying Zhang, LeYao Xiao, Qian Liu, XinYi Zhang, MingDan Li, YaLi Xu, Mei Dai, Fei Zhao, YouShu Shen, Jordan Tovera Salvador, Ping Yang

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Functional Development of the Human Gastrointestinal Tract: Hormone- and Growth Factor-Mediated Regulatory Mechanisms by Daniel Ménard

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Family cohesion, children’s thoughts, and children’s cognitive assessments: Mediating role of sport anxiety by Юмна Али, Сайед М. И. Шах

“…Hayes’ PROCESS Macro further demonstrated that sport anxiety has a significant mediating effect between thoughts and cognitive outcomes, including negative self-evaluations, off-task evaluations, positive self-evaluations, and on-task thoughts. …”
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From Innovation and Compatibility to The Intention to Adopt Mobile Payment with User Expectations as The Mediating Factor by Lady Lady, Kelvin Lie, Hesniati Hesniati, Candy Candy

“…A noteworthy finding is that Comp significantly influences BI, with EE acting as a mediator.…”
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Carbonic anhydrase 2 mediates anti-obesity effects of black tea as thermogenic activator by Peng Ma, Jie Xiao, Biyu Hou, Ping He, Xinyu Yang, Yisa Wang, Zijing Wang, Tianshu Xu, Xiuying Yang, Xuan Zhu, Shasha Xiang, Song Li, Guanhua Du, Jian Ying, Guifen Qiang

“…Our findings demonstrated anti-obesity effect of BTE as thermogenic activator through CA2-mediated BAT thermogenesis and WAT browning via CA2-AKT-UCP1 signaling pathway, which could be developed as promising anti-obesity agent with good safety and efficacy.…”
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Therapeutic Applicability of Anti-Inflammatory and Proresolving Polyunsaturated Fatty Acid-Derived Lipid Mediators by Gerard L. Bannenberg

“…Different aspects of the therapeutic applicability of lipid mediators have been addressed here, and indicate that the development of innovative pharmacotherapy based on anti-inflammatory and proresolution lipid mediators presents novel prospects for the treatment of inflammatory disease.…”
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Metformin blocks BIK1-mediated CPK28 phosphorylation and enhances plant immunity by Yazhou Bao, Qian Zhang, Hai Zhu, Yong Pei, Yaning Zhao, Yixin Li, Peiyun Ji, Dandan Du, Hao Peng, Guangyuan Xu, Xiaodan Wang, Zhiyuan Yin, Gan Ai, Xiangxiu Liang, Daolong Dou

“…Conclusion: Collectively, our data suggest that MET enhances plant immunity by blocking BIK1-mediated CPK28 phosphorylation.…”
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The Regulation of Inflammatory Mediators in Acute Kidney Injury via Exogenous Mesenchymal Stem Cells by Tao Du, Ying-Jian Zhu

“…Mediators of Inflammation…”
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Microplastics mediates the spread of antimicrobial resistance plasmids via modulating conjugal gene expression by Qiu E. Yang, Zhenyan Lin, Dehao Gan, Minchun Li, Xuedan Liu, Shungui Zhou, Timothy R. Walsh

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Ultraviolet Radiation and the Slug Transcription Factor Induce Proinflammatory and Immunomodulatory Mediator Expression in Melanocytes by Stephanie H. Shirley, Elizabeth A. Grimm, Donna F. Kusewitt

“…UVR induces keratinocytes to secrete proinflammatory and immunomodulatory mediators that promote inflammation and skin tumor development; expression of the slug transcription factor in keratinocytes is required for maximal production of these mediators. …”
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Optimization of Vacuum Microwave-Mediated Extraction of Syringoside and Oleuropein from Twigs of Syringa oblata by Xiangping Liu, Xuemin Jing, Guoliang Li

“…A vacuum microwave-mediated method was used to extract syringoside and oleuropein from Syringa oblata twigs. …”
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Sleep as a Mediator in the Pathway Linking Environmental Factors to Hypertension: A Review of the Literature by Oluwaseun A. Akinseye, Stephen K. Williams, Azizi Seixas, Seithikurippu R. Pandi-Perumal, Julian Vallon, Ferdinand Zizi, Girardin Jean-Louis

“…Through this narrative review of the extant literature, we highlight that poor sleep quality mediates the relationship between environmental factors and hypertension. …”
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Isoacteoside alleviates hepatocellular carcinoma progression by inhibiting PDHB-mediated reprogramming of glucose metabolism by Lijun Zhao, Haonan Qi, Weiting Liu, Huiying Lv, Peixian Li, Wenyue Liu, Ruili Sun, Qiongzi Wang, Xiangpeng Wang

“…Mechanistically, PDHB mediates metabolic reprogramming by binding to the promoter regions of SLC2A1, GPI, and PKM2, promoting glycolysis-related gene transcription, contributes to HCC sorafenib resistance. …”
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Inflammatory disease progression shapes nanoparticle biomolecular corona-mediated immune activation profiles by Jacob R. Shaw, Nicholas Caprio, Nhu Truong, Mehari Weldemariam, Anh Tran, Nageswara Pilli, Swarnima Pandey, Jace W. Jones, Maureen A. Kane, Ryan M. Pearson

“…Integrated multi-omics analysis of proteomics, lipidomics, metabolomics, and cytokine datasets highlight a set of differentially enriched TLR4 ligands that correlate with dynamic NP corona-mediated immune activation. Pharmacological inhibition and genetic knockout studies validate that NP coronas mediate this response through TLR4/MyD88/NF-κB signaling. …”
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Wildfires mediate carbon transfer from land to lakes across boreal and temperate regions by Mathilde Bélair, Ian M. McCullough, Christopher T. Filstrup, Jennifer A. Brentrup, Jean-François Lapierre

“…The greater quantity and dominance of dissolved organic carbon in burned lakes over other carbon forms with different turnover rates and fates suggest a potential fire-mediated carbon export up to several years post fire with a yet undetermined fate in northern forested watersheds and with important implications for regional to global carbon budgets.…”
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6-thioguanine inhibits EV71 replication by reducing BIRC3-mediated autophagy by Qiao You, Jing Wu, Ruining Lyu, Yurong Cai, Na Jiang, Ye Liu, Fang Zhang, Yating He, Deyan Chen, Zhiwei Wu

“…Mechanistically, 6-TG treatment reduced the expression of baculoviral IAP repeat containing 3 (BIRC3), and further inhibited EV71 replication by attenuating BIRC3-mediated the complete autophagy. Conclusions 6-TG exerted a significant inhibitory effect on EV71 infection in vitro and prevented EV71-induced the complete autophagy by decreasing BIRC3 expression. …”
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NADPH Oxidase 2-Mediated Insult in the Auditory Cortex of Zucker Diabetic Fatty Rats by Zheng-De Du, Wei Wei, Shukui Yu, Qing-Ling Song, Ke Liu, Shu-Sheng Gong

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The role of universities’ social responsibility in enhancing business sustainability: Mediating role of entrepreneurial culture by Abdelrehim Awad

“…Additionally, entrepreneurial culture mediates this relationship, contributing an indirect effect of 0.446 and amplifying the total impact of social responsibility on business sustainability to 70.1%. …”
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Natural Compounds as Regulators of NLRP3 Inflammasome-Mediated IL-1β Production by József Tőzsér, Szilvia Benkő

“…Mediators of Inflammation…”
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