Inflammatory Mediators and Angiogenic Factors in Choroidal Neovascularization: Pathogenetic Interactions and Therapeutic Implications by Claudio Campa, Ciro Costagliola, Carlo Incorvaia, Carl Sheridan, Francesco Semeraro, Katia De Nadai, Adolfo Sebastiani, Francesco Parmeggiani

“…Mediators of Inflammation…”
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Mindfulness Practice and Work Performance: The Mediating Role of Emotional Intelligence and Psychological Capital by Hoang Cuu Long, Ho Minh An, Pham Thi Phuong Dung, Nguyen Le Dinh Quy

“…In addition, emotional intelligence partially mediated the relationship between mindfulness and performance, as evidenced by a greater indirect effect than direct effect. …”
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The Mediating Role of Basic Psychological Needs and Meaning in Life in Adolescent Suicidal Ideation by Jiayi Li, Jinqian Liao, Shuai Chen, Cheng Guo

“…Statistical analyses, including mediation and chain mediation analyses, were conducted to examine the relationships between parental psychological control, basic psychological needs, meaning in life, and suicidal ideation. …”
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The molecular basis of Human FN3K mediated phosphorylation of glycated substrates by Ankur Garg, Kin Fan On, Yang Xiao, Elad Elkayam, Paolo Cifani, Yael David, Leemor Joshua-Tor

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The role of gaze in meaning negotiation episodes in video synchronous computer-mediated interactions by Li Chenxi

“…Therefore, this study aims to investigate the webcam’s role in video synchronous computer-mediated communication (SCMC). Negotiation for meaning episodes, in which interlocutors try to resolve non-understanding through verbal interaction, were selected for analysis because they are widely believed to be helpful for second language acquisition. …”
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Investigating the Relationship between Attachment Styles and Academic Burnout: The Mediating Role of Alexithymia by Zahra Amanat, Majid Barzegar, Azarmidokht Rezaei, Hossein Bagholi

“…The data analysis was conducted using structural equation modeling, with the mediation role being examined through the application of the bootstrap in AMOS. …”
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The Role of Neuroglial Crosstalk and Synaptic Plasticity-Mediated Central Sensitization in Acupuncture Analgesia by Zhongxi Lyu, Yongming Guo, Yinan Gong, Wen Fan, Baomin Dou, Ningcen Li, Shenjun Wang, Yuan Xu, Yangyang Liu, Bo Chen, Yi Guo, Zhifang Xu, Xiaowei Lin

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Growth Hormone-Releasing Hormone and Its Analogues: Significance for MSCs-Mediated Angiogenesis by Xiangyang Xia, Quanwei Tao, Qunchao Ma, Huiqiang Chen, Jian’an Wang, Hong Yu

“…We also discussed the relationship between GHRH analogues and MSC-mediated angiogenesis. The analyses provide new insights into molecular pathways of MSCs-based therapies and their augmentation by GHRH analogues.…”
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The Relationship between Insecure Attachment to Depression: Mediating Role of Sleep and Cognitive Reappraisal by Yige Liu, Hongfan Li, Xiayue Xu, Yukun Li, Zhutao Wang, Huan Zhu, Xia Zhang, Shan Jiang, Naling Li, Simeng Gu, Fushun Wang, Jason H. Huang

“…The results showed that (1) insecure attachment positively predicted poor sleep quality; (2) sleep quality partially affected depression, possibly due the same stress neuromodulators such as norepinephrine and cortisol; and (3) cognitive reappraisal moderated the mediating path leading from attachment anxiety to poor sleep quality. …”
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Impact of strategic orientation on sustainable competitive advantage: the mediating role of organizational capabilities by Mohammed Majeed, Ahmed Tijani, Kwame Simpe Ofori, Aidatu Abubakari, George Oppong Appiagyei Ampong

“…Specifically, it analyzes the impact of strategic orientation on organizational capabilities, and how social media capability mediates the relationship between strategic orientation and sustainable competitive advantage. …”
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Tau mediates the reshaping of the transcriptional landscape toward intermediate Alzheimer’s disease stages by Giacomo Siano, Giacomo Siano, Martina Varisco, Marco Terrigno, Congwei Wang, Arianna Scarlatti, Vincenzo Iannone, Marco Groth, Marie-Christine Galas, Jeroen J. M. Hoozemans, Alessandro Cellerino, Alessandro Cellerino, Antonino Cattaneo, Cristina Di Primio

“…We previously demonstrated that destabilization and nuclear delocalization of Tau alter the expression of glutamatergic genes, mediating early neuronal damage.MethodsIn this study, we discovered that changes in Tau availability are linked to global alterations in gene expression that affect multiple neuronal pathways. …”
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Evidence for microbially-mediated tradeoffs between growth and defense throughout coral evolution by Hannah E. Epstein, Tanya Brown, Ayọmikun O. Akinrinade, Ryan McMinds, F. Joseph Pollock, Dylan Sonett, Styles Smith, David G. Bourne, Carolina S. Carpenter, Rob Knight, Bette L. Willis, Mónica Medina, Joleah B. Lamb, Rebecca Vega Thurber, Jesse R. Zaneveld

“…Because microbes can influence multiple aspects of host physiology, including growth rate and susceptibility to disease or stress, changes in animal-microbial symbioses have the potential to mediate life-history tradeoffs. Scleractinian corals provide a biodiverse, data-rich, and ecologically-relevant host system to explore this idea. …”
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Wildland-Urban Interface Case Study: Mediating for Change in Martin County, Florida by Lauren McDonell, Martha C. Monroe

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The Mediating Role of Communication in Fostering Religious Tolerance within a Diverse Society by Totok Wahyu Abadi, Andrea Resha Zetira, Ahmad Riyadh Umar Balahmar, Kirti Dang Longani

“…The data was analysed using Structural Equation Modelling (SEM) to test the relationships between the variables and the mediating role of communication behaviour. The results show that communication behaviour plays a crucial role in mediating the influence of social prejudice, local wisdom, social piety, and religious identity on religious tolerance. …”
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Skin Microbiota: Mediator of Interactions Between Metabolic Disorders and Cutaneous Health and Disease by Magdalini Kreouzi, Nikolaos Theodorakis, Maria Nikolaou, Georgios Feretzakis, Athanasios Anastasiou, Konstantinos Kalodanis, Aikaterini Sakagianni

“…By addressing systemic metabolic dysfunction and microbiota-mediated pathways, precision strategies are paving the way for improved patient outcomes in dermatologic care.…”
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Suppressive Effect of Insulin on the Gene Expression and Plasma Concentrations of Mediators of Asthmatic Inflammation by Husam Ghanim, Kelly Green, Sanaa Abuaysheh, Manav Batra, Nitesh D. Kuhadiya, Reema Patel, Antoine Makdissi, Sandeep Dhindsa, Ajay Chaudhuri, Paresh Dandona

“…Following our recent demonstration that the chronic inflammatory and insulin resistant state of obesity is associated with an increase in the expression of mediators known to contribute to the pathogenesis of asthma and that weight loss after gastric bypass surgery results in the reduction of these genes, we have now hypothesized that insulin suppresses the cellular expression and plasma concentrations of these mediators. …”
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Oxygen Defect-Mediated Magnetism in Fe-C Codoped TiO2 by Zhaorui Zou, Zhongpo Zhou, Haiying Wang, Meng Du

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The emergence of DNAM-1 as the facilitator of NK cell-mediated killing in ovarian cancer by Rachel Pounds, Rachel Pounds, Wayne Croft, Hayden Pearce, Tasnia Hossain, Kavita Singh, Janos Balega, David N. Jeevan, Sudha Sundar, Sudha Sundar, Sean Kehoe, Jason Yap, Jason Yap, Paul Moss, Jianmin Zuo

“…Expression of PVR, the DNAM-1 ligand, was significantly increased on tumours and DNAM-1 mediated NK cell lysis of primary tumour tissue was observed in vitro.DiscussionThese findings reveal profound modulation of the tumour tissue and systemic profile of NK cells which likely contributes to the high rates of local progression and metastasis seen with OC. …”
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A mitochondria-to-nucleus regulation mediated by the nuclear-translocated mitochondrial lncRNAs. by Jia Li, Ruoling Bai, Yulian Zhou, Xu Song, Ling Li

“…Here, we identify functional implication of the mtlncRNAs MDL1AS, lncND5 and lncCyt b in retrograde regulation. Mediated by HuR and PNPT1 proteins, the mtlncRNAs undergo a mitochondria-to-nucleus traveling and then regulate a network of nuclear genes. …”
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Wogonin Inhibits Cardiac Hypertrophy by Activating Nrf-2-Mediated Antioxidant Responses by Xiaowen Shi, Bin Zhang, Zhenliang Chu, Bingjiang Han, Xueping Zhang, Ping Huang, Jibo Han

“…Using gene-specific siRNA for Nrf-2, we discovered that these antioxidative effects of Wog are mediated through Nrf-2 induction. Conclusions. Our results provide further evidence for the potential use of Wog as an antioxidative agent for treatment of cardiac hypertrophy, and Nrf-2 might serve as a therapeutic target in the treatment of cardiac hypertrophy.…”
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