Emergency medicine physician supervision and mortality among patients receiving care from non-physician clinicians in a task-sharing model of emergency care in rural Uganda: a retr... by Rebecca Leff, Brian Rice, Bradley Dreifuss, Heather Hammerstedt, Mark Bisanzo, Stacey Chamberlain, Ashley Pickering, Colleen Laurence, Prisca Mary Kizito, Steven Jonathan Kisingiri, Charles Ndyamwijuka, Serena Nakato, Lema Felix Adriko

“…Objectives To assess the association between emergency medicine physician supervision and 3-day mortality for patients receiving care from non-physician clinicians in a task-sharing model of emergency care in rural Uganda.Design Retrospective cohort analysis with multivariable logistic regression.Setting Single rural Ugandan emergency unit.Participants All patients presenting for care from 2009 to 2019.Interventions Three cohorts of patients receiving care from non-physician clinicians had three different levels of physician supervision: ‘Direct Supervision’ (2009–2010) emergency medicine physicians directly supervised all care; ‘Indirect Supervision’ (2010–2015) emergency medicine physicians were consulted as needed; ‘Independent Care’ (2015–2019) no emergency medicine physician supervision.Primary outcome measure Three-day mortality.Results 38 033 ED visits met inclusion criteria. …”
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Elevated blood glucose and unfavourable tuberculosis treatment outcomes in a low-income setting: findings from a prospective cohort study in Eswatini by Diederick E Grobbee, Kerstin Klipstein-Grobusch, Kennedy Otwombe, Victor Williams, Alinda G Vos-Seda, Marianne Calnan, Colani S Ngwenya, Samson Haumba, Lindiwe Mdluli-Dlamini

“…To understand this dual burden in Eswatini, we describe the prevalence and predictors of elevated baseline blood glucose and unfavourable tuberculosis treatment outcomes.Methods We conducted a prospective cohort study at 11 health facilities in Eswatini and included adults ≥18 years commencing tuberculosis treatment. Blood glucose measurements were taken at baseline, months 2 and 5, and patients’ sociodemographic and clinical data were extracted. …”
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Integrating Two-Tier Optimization Algorithm With Convolutional Bi-LSTM Model for Robust Anomaly Detection in Autonomous Vehicles by Moneerah Alotaibi, Manal Abdullah Alohali, Khalid Mahmood, Asma A. Alhashmi, Jehad Saad Alqurni, Sultan Refa Alotaibi, Ahmad A. Alzahrani, Imene Issaoui

“…AVs play a significant role since they are measured as a vital module of smart cities. The AV is an advanced automobile efficient in preserving secure driving by evading collisions formed by drivers. …”
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Significance of Heparin-Binding Protein and D-dimers in the Early Diagnosis of Spontaneous Bacterial Peritonitis by Tomasz Mikuła, Mariusz Sapuła, Joanna Jabłońska, Joanna Kozłowska, Wojciech Stańczak, Dagny Krankowska, Alicja Wiercińska-Drapało

“…Sensitivities, specificities, and positive and negative predictive values for SBP were calculated for the aforementioned makers of inflammation. Measurements and Main Results. A total of 63 patients with decompensated liver cirrhosis and ascites participated in the study. …”
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Mental health in the COVID-19 pandemic: A longitudinal analysis of the CLoCk cohort study. by Laura Panagi, Simon R White, Snehal M Pinto Pereira, Manjula D Nugawela, Isobel Heyman, Kishan Sharma, Terence Stephenson, Trudie Chalder, Natalia K Rojas, Emma Dalrymple, Kelsey McOwat, Ruth Simmons, Olivia Swann, CLoCk Consortium, Tamsin Ford, Roz Shafran

“…Findings from multilevel mixed-effects linear regression model showed that on average mental health symptoms as measured by the total SDQ score increased over time (B = 0.11 (per month), 95% CI = 0.09 to 0.12, p < 0.001) although this increase was small and not clinically significant. …”
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Phytochemical Profile Screening and Selected Bioactivity of <i>Myrtus communis</i> Berries Extracts Obtained from Ultrasound-Assisted and Supercritical Fluid Extraction by Ilir Mërtiri, Gigi Coman, Mihaela Cotârlet, Mihaela Turturică, Nicoleta Balan, Gabriela Râpeanu, Nicoleta Stănciuc, Liliana Mihalcea

“…The antidiabetic potential was evaluated <i>in vitro</i> by measuring the inhibition of <i>α</i>-amylase from porcine pancreas (type I-A). …”
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Risk of hemorrhagic fever with renal syndrome associated with meteorological factors in diverse epidemic regions: a nationwide longitudinal study in China by Nan Chang, Wenzhong Huang, Yanlin Niu, Zhihu Xu, Yuan Gao, Tingting Ye, Zihao Wang, Xiaohui Wei, Yuming Guo, Qiyong Liu

“…Targeted preventive measures should be taken during cold and dry spring days in Rattus-dominant regions, and during warm and moderately humid winter days in Apodemus-dominant regions. …”
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Associations between media parenting practices and early adolescent consumption of R-rated movies and mature-rated video games by Jason M. Nagata, Karen Li, Shirley S. Sui, Jonanne Talebloo, Christopher D. Otmar, Iris Yuefan Shao, Orsolya Kiss, Kyle T. Ganson, Alexander Testa, Jinbo He, Fiona C. Baker

“…Conclusions Media parenting practices such as monitoring or limiting screen use are significantly associated with playing mature-rated video games and watching R-rated movies. Punitive measures, such as restricting screen time as a punishment are slightly associated with increased engagement with such content. …”
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Mortality Prediction Using SaO2/FiO2 Ratio Based on eICU Database Analysis by Sharad Patel, Gurkeerat Singh, Samson Zarbiv, Kia Ghiassi, Jean-Sebastien Rachoin

“…S/F ratio is a noninvasive continuous method of measuring hypoxemia as compared to P/F ratio. Our study shows that the S/F ratio is a better predictor of mortality than the more widely used P/F ratio to monitor and manage hypoxemia.…”
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Towards a cervical cancer-free future: women’s healthcare decision making and cervical cancer screening uptake in sub-Saharan Africa by Bright Opoku Ahinkorah, Abdul-Aziz Seidu, Richard Gyan Aboagye, Bernard Yeboah-Asiamah Asare, Joshua Okyere, Bupe Mwamba

“…We employed multilevel binary logistic regression modelling.Setting Sub-Saharan Africa.Participants Women aged 15–49 years in Benin (n=5282), Côte d’Ivoire (n=1925), Cameroon (n=7558), Kenya (n=6696), Namibia (n=1990) and Zimbabwe (n=5006).Primary outcome measures Cervical cancer screening uptake.Results The overall prevalence of cervical cancer screening across the six sub-Saharan African countries was 13.4%. …”
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Associations between social determinants of health and mental health disorders among U.S. population: a cross-sectional study by S. Tanarsuwongkul, J. Liu, M. Spaulding, K. Perea-Schmittle, M. Lohman, Q. Wang

“…The strong correlations between the SDOH summary score and mental health disorders indicate a possible use of the summary score as a measure of risk of developing mental health disorders. …”
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Life cycle assessment of paper products based on recycled and virgin fiber by J. Simamora, E.I. Wiloso, M. Yani

“…All impact magnitudes were measured in functional units per 1 ton of paper product.CONCLUSION: The study has revealed the environmental impact of paper products produced in Indonesia. …”
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Mortality and immunological indicators of men who have sex with men living with HIV on antiretroviral therapy: a 10-year retrospective cohort study in Southern China by Huaxiang Lu, Huanhuan Chen, Shujia Liang, Yuhua Ruan, He Jiang, Jinghua Huang, Guangjie Tan, Xiuling Wu, Jianjun Li, Chen Gong, Qiuying Zhu, Guanghua Lan

“…These were then incorporated into the Cox models in the form of repeated measurements to evaluate the associations (Adjusted-hazard ratios, aHRs) and 95% confidence intervals (95% CIs) of these immunological indicators with mortality at different stages. …”
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Cerebral Ultrasound at Term-Equivalent Age: Correlations with Neuro-Motor Outcomes at 12–24 Months Corrected Age by Adrian Ioan Toma, Vlad Dima, Lidia Rusu, Alexandra Floriana Nemeș, Bogdan Florin Gonț, Alexandra Arghirescu, Andreea Necula, Alina Fieraru, Roxana Stoiciu, Larisa Andrășoaie, Loredana Mitran, Claudia Mehedințu, Al Jashi Isam

“…The neurologic evaluation was performed at 12 and 24 months of corrected age, according to the Amiel Tison neurologic examination, and the items from the calendar of motor acquisitions were used as outcome measures of the study—gross and fine motor subsets. …”
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Within- and between-day test–retest reliability of responses to rapid bilateral anterolateral magnetic phrenic nerve stimulation in healthy humans (ReStim) by Kyle G. P. J. M. Boyle, Andrea A. Beglinger, Heinrich Häusler, Anna Stahel, Esther I. Schwarz, Esther I. Schwarz, Christina M. Spengler, Christina M. Spengler

“…Relative and absolute reliability of both Pdi,mean and VT were quantified by calculating intraclass correlation coefficients (ICC) and standard error of measurements (SEM), respectively. An ordinal regression was used to determine changes of sensory ratings within and between days.ResultsAt all stimulator outputs, within-day Pdi,mean displayed “good” reliability (ICC range 0.78–0.89). …”
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Effects of Bride Price on Women's Rights Among the Bakiga in Kabale District: A Case Study of Kitumba Sub-County. by Asiimwe, Bettus

“…It was guided by the following objectives; to examine the reasons why the bride price is paid in Kitumba Sub County, to assess the effects of bride price on women's rights in Kitumba Sub County, and to establish measures aimed at reducing women's rights abuse in Kitumba Sub County. …”
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CircUCK2(2,3) promotes cancer progression and enhances synergistic cytotoxicity of lenvatinib with EGFR inhibitors via activating CNIH4–TGFα–EGFR signaling by Xindong Wei, Anfeng Si, Shuai Zhao, Yi Fu, Jilei Li, Kedeerya Aishanjiang, Yujie Ma, Chang Yu, Bo Yu, Chunhong Cui, Hui Wang, Xianming Kong, Shibo Li, Xiaoni Kong, Ying Tong, Hailong Wu

“…CircUCK2(2,3) levels were measured in two independent HCC cohorts using quantitative real-time PCR (qRT–PCR). …”
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Charlson comorbidity index has no incremental value for mortality risk prediction in nursing home residents with COVID-19 disease by Anum Zahra, Maarten van Smeden, Petra J. M. Elders, Jan Festen, Jacobijn Gussekloo, Karlijn J. Joling, Anouk van Loon, Kim Luijken, René J. F. Melis, Simon P. Mooijaart, Karel G. M. Moons, Geeske Peeters, Harmke A. Polinder-Bos, Fenne Wouters, Anne de Hond

“…The addition of CCI did not improve these predictive performance measures. Conclusion The addition of the CCI as a vulnerability indicator did not improve short-term mortality prediction in NH residents. …”
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Prioritizing breast cancer surgeries: insights from the KRONOS SCORE by Lucía Navarro, Lucía Navarro, Lucía Navarro, Luis Perez-Bartivas, Luis Perez-Bartivas, Luis Perez-Bartivas, David Ponferrada, David Ponferrada, David Ponferrada, Javier Cejas, Javier Cejas, Javier Cejas, Juan Adrián Camús, Juan Adrián Camús, Juan Adrián Camús, Natalia Rangel, Natalia Rangel, Natalia Rangel, Maria Porras, Cristina Morales Estevez, Cristina Morales Estevez, Cristina Morales Estevez, Amalia Palacios Eito, Amalia Palacios Eito, Amalia Palacios Eito, Pilar Rioja, Pilar Rioja, Pilar Rioja, Marina Alvarez, Marina Alvarez, Marina Alvarez, Enrique Aranda, Enrique Aranda, Enrique Aranda, Juan De La Haba-Rodríguez, Juan De La Haba-Rodríguez, Juan De La Haba-Rodríguez

“…IntroductionIn many healthcare systems, the time to surgery (TTS) is used as a quality measure in breast cancer (BC) care. Although guidelines suggest that a waiting period of up to four weeks is acceptable, this is often exceeded, potentially impacting treatment outcomes. …”
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LRP11 promotes stem-like T cells via MAPK13-mediated TCF1 phosphorylation, enhancing anti-PD1 immunotherapy by Zhishui Chen, Gang Chen, Li Chen, Xiangli Zhao, Lingjuan Sun, Zhibo Ma, Xiaosheng Tan, Yuhao Tu, Jingzeng Wang, Peixiang Lan

“…Flow cytometry was used to measure cell proportions and activation status. Molecular interactions and TCF1 status were examined using Western blotting. …”
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