Consumption of Raw Herbal Medicines Is Associated with Major Public Health Risks amongst Ugandans by Fred, Ssempijja, Keneth Iceland, Kasozi, Ejike, Daniel Eze, Andrew, Tamale, Sylvia Anurika, Ewuzie, Kevin, Matama, Justine, Ekou, Paul, Bogere, Regan, Mujinya, Grace Henry, Musoke, Jovile Kasande, Atusiimirwe, Gerald, Zirintunda, Muhamudu, Kalange, Joel, Lyada, Ritah, Kiconco, Theophilus, Pius, Christopher, Nandala, Roland Mugisha, Kamugisha, Yunusu, Hamira, Edgar Mario, Fernandez, Simon Peter, Musinguzi

“…+e EDI, THQ, and ILCR were modelled and significance was measured at 95% confidence. Results. +e study showed that mean ± SEM concentrations of heavy metals were highest in the order of Cr, 121.8 ± 4.291 ppm > Ni, 84.09 ± 2.725 ppm > Zn, 53.87 ± 2.277 ppm > Pb, Hindawi Journal of Environmental and Public Health Volume 2020, Article ID 8516105, 10 pages https://doi.org/10.1155/2020/8516105 40.61 ± 3.891 ppm > Cu, 28.75 ± 2.202 ppm > Fe, 14.15 ± 0.7271 ppm > Co, 7.923 ± 0.7674 ppm > Cd, 0.1163 ± 0.005714 ppm. …”
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Association of coronary revascularisation after physician-referred non-invasive diagnostic imaging tests with outcomes in patients with suspected coronary artery disease: a post ho... by Takao Kato, Moriaki Inoko, Naoya Matsumoto, Yukari Uemura, Masanao Naya, Mitsuru Momose, Satoshi Hida, Takao Yamauchi, Takatomo Nakajima, Eriko Suzuki, Tohru Shiga, Nagara Tamaki

“…We assessed the effect of revascularisation (within 90 days) in each diagnostic imaging stratum and the interaction between the two strata.Primary and secondary outcome measures Major adverse cardiac events (MACEs), including death, myocardial infarction, hospitalisation for heart failure and late revascularisation, were followed up for 1 year. …”
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Assessment of grain starch content and responses to CMS-S and CMS-C in high-starch maize hybrids by M. R. Firsova, B. R. Shomakhov, R. S. Kushkhova, Z. T. Khashirova, R. A. Kudaev, A. Kh. Gyaurgiev, S. P. Appaev, A. M. Kagermazov, A. V. Khachidogov, A. I. Buzurtanov, K. Sh. Badurgova, M. A. Bazgiev, V. G. Goldshtein, V. I. Khoreva, E. B. Khatefov

“…Native starch content in the grain of hybrids with highest yields was measured at the All-Russian Research Institute of Starch and Starch-Containing Raw Materials Processing using the method proposed by L. …”
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VCP regulates early tau seed amplification via specific cofactors by Sushobhna Batra, Jaime Vaquer-Alicea, Clarissa Valdez, Skyler P. Taylor, Victor A. Manon, Anthony R. Vega, Omar M. Kashmer, Sourav Kolay, Andrew Lemoff, Nigel J. Cairns, Charles L. White, Marc I. Diamond

“…We exposed cells to fibrils or brain homogenates in cell culture media and measured effects on uptake and induction of intracellular tau aggregation following various genetic and pharmacological manipulations of VCP. …”
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Longitudinal changes in the 6-minute walk test and the Glittre-activities of daily living test in adults with cystic fibrosis by Vera Lucia Barros Abelenda, Cláudia Henrique da Costa, Mônica de Cássia Firmida, Raphael Freitas Jaber de Oliveira, Rogério Rufino, Agnaldo José Lopes

“…Pulmonary function tests, handgrip strength (HGS), and the Cystic Fibrosis Questionnaire-Revised (CFQ-R) were conducted. Measurements were collected at baseline (T1) and 1 year later (T2). …”
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Prevalence of anaemia and the associated factors among hospitalised people living with HIV receiving antiretroviral therapy in Southwest China: a cross-sectional study by Jie Yuan, Hai Long, Min Liu, Juan He, Jue Liu, Yu Wu, Wenzhan Jing, Min Du, Manna Zhang, Yaping Wang, Su Song, Siqi Liu, Guiying Cao, Yuedong Liang, Xiaoxin Xie, Yanhua Fu

“…Objectives To estimate anaemia prevalence and the associated factors among hospitalised people living with HIV (PLHIV) receiving antiretroviral therapy (ART).Design A cross-sectional study.Setting PLHIV receiving ART and hospitalised in a specialised hospital for infectious disease in Guizhou Province, Southwest China, between 1 January 2018 and 31 March 2021.Participants A total of 6959 hospitalised PLHIV aged ≥18 years and receiving ART were included in this study.Primary and secondary outcome measures Anaemia was diagnosed as a haemoglobin concentration <120 g/L for non-pregnant females and <130 g/L for males. …”
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An Overview of Patient-reported Outcomes for Men with Prostate Cancer: Results from the PIONEER Consortium by Sebastiaan Remmers, Katharina Beyer, Tariq A. Lalmahomed, Peter Prinsen, Nicole J.E. Horevoorts, Nora Tabea Sibert, Christoph Kowalski, Francesco Barletta, Oliver Brunckhorst, Giorgio Gandaglia, Jochem R.N. van der Voort van Zyp, Emma J. Smith, Andre Deschamps, Laurence Collette, Philip Cornford, Susan Evans-Axelsson, James N’Dow, Mieke Van Hemelrijck, Monique J. Roobol, Lionne D.F. Venderbos

“…Background and objective: Patient-reported outcome measures (PROMs) are increasingly being used to capture the patients’ perspective of their functional status and quality of life (QoL). …”
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Evaluation of waning of IgG antibody responses after rVSVΔG-ZEBOV-GP and Ad26.ZEBOV, MVA-BN-Filo Ebola virus disease vaccines: a modelling study from the PREVAC randomized trial by Simon Valayer, Marie Alexandre, Mélanie Prague, Abdoul Habib Beavogui, Seydou Doumbia, Mark Kieh, Brian Greenwood, Bailah Leigh, Marie Poupelin, Christine Schwimmer, Samba O. Sow, Irina Maljkovic Berry, Jens H. Kuhn, Daniela Fusco, Natasha Dubois Cauwelaert, Deborah Watson-Jones, Rodolphe Thiébaut, Yves Lévy, Yazdan Yazdanpanah, Laura Richert, Edouard Lhomme

“…Challenges associated with measuring long-term clinical protection warrant the evaluation of immune response kinetics after vaccination. …”
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The Positive Regulatory Effect of DBT on Lipid Metabolism in Postpartum Dairy Cows by Zheng Zhou, Kang Yong, Zhengzhong Luo, Zhenlong Du, Tao Zhou, Xiaoping Li, Xueping Yao, Liuhong Shen, Shumin Yu, Yixin Huang, Suizhong Cao

“…The levels of serum biochemical indices were measured at three time points in the three groups using commercial kits. …”
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Estimation of tuberculosis incidence at subnational level using three methods to monitor progress towards ending TB in India, 2015–2020 by Swati Mahajan, Amar Shah, Sarit Sharma, Rituparna Das, Kathiresan Jeyashree, Mathavaswami Vijayageetha, Bhavesh Modi, Burugina Nagaraja Sharath, Vijay Singh, Shamim Mannan, Sairu Philip, Jasleen Kaur, Ranjani Ramachandran, Raghuram Rao, Sriram Selvaraju, Bency Joseph, Vaibhav Shah, Kiran Rade, Lalit Sankhe, Surinder Singh, Sandeep Chauhan, Anupam Banerjee, Devender Kumar, Ganapathy Kalaiselvan, Bhavin Vadera, Paras Mehta, Meenakumari Natarajan, Manoj Murhekar, Aswathy Sreedevi, Jeromie Thangaraj, Saravanakumar Velusamy, Sasidharan Akhil, Dhanapal Sudha Rani, Ramasamy Sabarinathan, Sakthivel Manikandanesan, Rajalakshmi Elumalai, Amarendra Mahapatra, Almas Shamim, Ashok Bhardwaj, Anil Purty, Anand Sridhar, Aniket Chowdhury, Asif Shafie, Avijit Choudhury, Deka Dhrubjyoti, Hardik Solanki, Krushna Sirmanwar, Kshitij Khaparde, Malik Parmar, Nisha Dahiya, Parija Debdutta, Quazi Ahmed, Ranjeet Prasad, Rohini Shinde, Rupali Baruah, Sandip Bharaswadkar, Shanta Achanta, Shibu Balakrishnan, Shivani Chandra, Sophia Khumukcham, Sudarsan Mandal, Sumitha Chalil, Venkatesh Roddawar, Kuldeep Sachdeva, Jayakrishna Kurada, Mayank Sharma, Debajyoti Mohapatra, Yogesh Patel, Sapna Thekkepat, Karthikeyan Kumaraswamy, Mallika Tharakan, Shramana Majumdar, Vrinda Manocha, Sukriti Chauhan, Shekhar Waikar, Puja Ambule, Krithika Murali, Devi Madhavi Bhimarasetty, Tulika Goswami, Darshan Mahyavanshi, Krutarth Bhrahmbhatt, Bhautik Modi, Anmol Gupta, Sunil Raina, Rajiv Kumar Gupta, Ratnesh Sinha, Manju Toppo, Gajen Medhi, Swati M Patki, Bishnu Ram Das, Lisa Sarangi, Afsal Hakim, Suresh Balan, Baer Philip Ravikumar, Subrata Baidya, Abhik Sinha, Boddepalli Nagendra Naidu, Bikash Chandra Nayak, Anoop Dev, Pallavi Boro, Debarshi Paul, Amrita Sarkar, Bhavesh Bariya, Jatin Chhaya, Dixit Chauhan, Mithun Sanghavi, Nilesh Thakor, Rohit Ram, Hinal Baria, Abhilash Sood, Anupam Parashar, Yangchen Dolma, Rakesh Bahl, Dilip Kumar, Mohammad Salim Khan, A K Jayasree, Zinia Nujum, Sheela P Haveri, Dinesh Bhatnagar, Subrata Kumar Palo, Priyesh Marskole, Prashant Verma, Dinesh Kumar Pal, Neelam Toppo, Sanjay R Quraishi, Sunil Panigrahi, Rambadan Chauhan, Jayashree Gothankar, Swapnali S Kadam, Dasi Rao, Sudhir Wanje, Pallavi Uplap, Ningombam Joenna Devi, Rikrak Ch Marak, Markordor Lyngdoh, Manoj B Patki, Satyajit Sundar Ray, Kavita Vasudevan, Mahesh Satija, Mahesh Choudhary, Mitin Parmar, Venkatesh Govindasamy, Karlapudi Nitesh Kumar, Goutham Thumari, Amar Tripura, Chanda Mog, Shampa Das, Ritesh Singh, Chandra Shekar Maity, Mamta Gehlawat

“…The survey continued until 30 Mycobacterium tuberculosis cases were identified in a district.Outcome measures We calculated a direct estimate of TB incidence based on incident cases identified in the survey. …”
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Incidence of shoulder dislocations in the UK, 1995–2015: a population-based cohort study by Gary S Collins, Sarah E Lamb, Sally Hopewell, Daniel Prieto-Alhambra, Andrew Judge, Amar Rangan, Andrew J Carr, Jonathan L Rees, Nigel K Arden, Katherine Edwards, Tim A Holt, Anjali Shah, Antonella Delmestri, Rafael A Pinedo-Villanueva

“…Coding of primary shoulder dislocations was validated using the CPRD general practitioner questionnaire service.Participants A cohort of 16 763 patients with shoulder dislocation aged 16–70 years during 1995–2015 were identified.Primary outcome measure Incidence rates per 100 000 person-years and 95% CIs were calculated.Results Correct coding of shoulder dislocation within CPRD was 89% (95% CI 83% to 95%), and confirmation that the dislocation was a ‘primary’ was 76% (95% CI 67% to 85%). …”
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Short-term association between ambient air pollution and childhood non-allergic rhinitis: A time-series study at a National Children's Regional Medical Center, in Hefei, China, fro... by Wei Cui, Hongxia Gao, Liran Zhu, Yuanyuan Xu, Haipeng Liu

“…Therefore, stronger control measures to mitigate air pollution must be implemented to decrease NAR incidence in the pediatric population.…”
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Efficacy and safety of guanabenz acetate treatment for non-alcoholic fatty liver disease: a study protocol for a randomised investigator-initiated phase IIa study by Atsushi Nakajima, Yasushi Honda, Kento Imajo, Masato Yoneda, Yuji Ogawa, Takaomi Kessoku, Takashi Kobayashi, Anna Ozaki, Asako Nogami, Satoru Saito, Michihiro Iwaki, Kosuke Tanaka, Atsushi Yamamoto, Kota Takahashi, Yuki Kasai, Noritoshi Kobayashi

“…The primary endpoint will be the percentage reduction in hepatic fat content (%) measured using MRI-proton density fat fraction from baseline by at least 3.46% at week 16 after treatment initiation.Ethics and dissemination Ethics approval was obtained from the Ethics Committee of Yokohama City University Hospital before participant enrolment (YCU021001). …”
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Protocol for a phase IV double-blind randomised controlled trial to investigate the effect of the 13-valent pneumococcal conjugate vaccine and the 23-valent pneumococcal polysaccha... by Tao Chen, Duolao Wang, Konstantinos Liatsikos, Stephen B Gordon, Hassan Burhan, Ben Morton, Tinashe K Nyazika, Bradford D Gessner, Helen Hill, Andrea Collins, Josh Hamilton, Kelly Davies, Fred Fyles, Phoebe Hazenberg, Elizabeth Begier, Angela Hyder-Wright, Sherin Pojar, Christopher Myerscough, Jesus Reine, Ryan E Robinson, Britta Urban, Elena Mitsi, Carla Solorzano, Angela Quinn, Kaijie Pan, Annaliesa S Anderson, Christian Theilacker, Daniela M Ferreira, Kelly Convey, James Court, Madlen Farrar, Lisa Hitchins, Ashleigh Howard, Lauren Kerruish, Samuel Latham, Annabel Murphy, Elissavet Nikolaou, Angelina Peterson

“…Density and duration of colonisation, comparison of acquisition rates using molecular methods and evaluation of the above measurements for individual SPN3 clades and SPN6B form the secondary objectives. …”
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Identification of novel autoantibodies in Sjögren’s disease by Fiona Engelke, Petra Budde, Salvatore De Vita, Thomas Dörner, Diana Ernst, Jan Gras, Harald Heidecke, Annika Loredana Kilian, Katja Kniesch, Ann-Sophie Lindemann, Luca Quartuccio, Jacob Ritter, Kai Schulze-Forster, Benjamin Seeliger, Hans-Dieter Zucht, Torsten Witte

“…To assess disease specificity, the novel autoantibodies were also measured in serum of patients with Rheumatoid Arthritis (RA, n=50), Systemic Lupus Erythematosus (SLE, n=49), and Systemic Sclerosis (SSc, n=37). …”
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Disrupting USP39 deubiquitinase function impairs the survival and migration of multiple myeloma cells through ZEB1 degradation by Jessy Sirera, Saharnaz Sarlak, Manon Teisseire, Alexandrine Carminati, Victoria J. Nicolini, Coline Savy, Patrick Brest, Thierry Juel, Christophe Bontoux, Marcel Deckert, Mickael Ohanna, Sandy Giuliano, Maeva Dufies, Gilles Pages, Frederic Luciano

“…The impact of USP39 knockdown via SiRNA was assessed through in vitro assays measuring cellular metabolism, clonogenic capacity, cell cycle progression, apoptosis, and sensitivity to BTZ. …”
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Caloric labels do not influence taste pleasantness and neural responses to erythritol and sucrose by Aleksandra Budzinska, Laura Byl, Fabienne Teysseire, Emilie Flad, Patrick Dupont, Bettina Wölnerhanssen, Anne Christin Meyer-Gerspach, Lukas Van Oudenhove, Nathalie Weltens

“…., beliefs, expectations) on reward system responses to NCSs, thereby changing their rewarding properties. We measured the impact of cognitive influences about the caloric content on brain responses and liking ratings to erythritol, a natural NCS with satiating properties, versus sugar (i.e., sucrose). …”
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Investigating Elevated E-Selectin and P-Selectin Levels in Non-Arteritic Anterior Ischemic Optic Neuropathy (NAION) Patients: The Stepping Stone to a Future Clinical Approach by Syntia Nusanti, Andhika Rachman, Brigitta Marcia Budihardja, Lourisa Ruth Eldinia, Nadia Delima Andini, Arief Kartasasmita, M Sidik, Seskoati Prayitnaningsih, Alida Roswita Harahap, Aria Kekalih, Tjahjono Darminto Gondhowiardjo

“…All patients were evaluated for E-selectin and P-selectin levels measured using flow cytometry.  Results: A total of 42 subjects comprising 14 hypercoagulation and 28 non-hypercoagulation subjects were included. …”
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A flood resilience assessment method of green-grey-blue coupled urban drainage system considering backwater effects by Yue Liu, Xiang Zhang, Jie Liu, Yao Wang, Haifeng Jia, Shiyong Tao

“…Among these approaches, green-grey-blue coupling measures have emerged as one of the prominent technical solutions. …”
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Comparative Analysis of Automated and Handheld Breast Ultrasound Findings for Small (≤1 cm) Breast Cancers Based on BI-RADS Category by Han Song Mun, Eun Young Ko, Boo-Kyung Han, Eun Sook Ko, Ji Soo Choi, Haejung Kim, Myoung Kyoung Kim, Jieun Kim

“…Patients with tumors measuring ≤1 cm on either modality were enrolled. Two breast radiologists retrospectively evaluated multiple imaging features, including shape, orientation, margin, echo pattern, and posterior characteristics and assigned BI-RADS categories. …”
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