Coexisting patterns and significance of serum HBV RNA and HBV DNA in patients with treatment-naïve chronic hepatitis B virus infection by Kun-yan Hao, Kun-yan Hao, Ye Fan, Yi-qing Zhang, Yue-cheng Yu

“…AimThe study aimed to explore the coexisting patterns and assess the significance of serum hepatitis B virus (HBV) RNA and traditional virological biomarkers in patients with antiviral treatment-naïve chronic hepatitis B virus (HBV) infection.MethodsSerum HBV RNA, HBV DNA, hepatitis B surface antigen (HBsAg), and hepatitis B envelope antigen (HBeAg) levels were measured and compared in patients with chronic hepatitis B virus infection. …”
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To what extent is the description of streets important in estimating local air quality: a case study over Paris by A. Squarcioni, A. Squarcioni, Y. Roustan, M. Valari, Y. Kim, K. Sartelet, L. Lugon, F. Dugay, R. Voitot

“…Simulation results for NO<span class="inline-formula">_<i>x</i></span>, NO<span class="inline-formula">₂</span>, and PM<span class="inline-formula">_2.5</span> concentrations over the city of Paris from both modeling approaches are compared with in situ measurements from traffic air quality stations. At stations located in downtown areas, with low traffic emissions, the street-network model MUNICH exhibits superior performance compared to the Subgrid approach for NO<span class="inline-formula">_<i>x</i></span> concentrations, while comparable results are obtained for NO<span class="inline-formula">₂</span>. …”
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Determination of Seroprevalence and Risk Factors of Crimean–Congo Haemorrhagic Fever (CCHF) in the Endemic Region in Turkey: A Population-Based Cross-Sectional Study by Rıza Çıtıl, Mücahit Eğri, Yalçın Önder, Fazilet Duygu, Yunus Emre Bulut, Özkan Yaşayancan, Nagehan Yıldız Çeltek, Şafak Şahin

“…The blood samples were taken, and anti-CCHFV IgG antibodies were measured with ELISA method. Results. 1272 (54.9%) out of 2319 participants were female, and the mean age was 47.3 ± 15.3. …”
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Duration of gargling and rinsing among frequent mouthwash users: a cross-sectional study by Eric P F Chow, Jane S Hocking, Catriona Bradshaw, Christopher Fairley, Kate Maddaford, Rebecca Wigan, Sabrina Trumpour, Tiffany Renee Phillips

“…Participants were observed and audio recorded using mouthwash.Primary and secondary outcome measures Descriptive analyses were conducted to calculate the median age, time rinsing and gargling, amount of mouthwash used and proportion of participants who rinsed, gargled or both, as determined from the audio files. …”
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Dihydrotanshinone I enhanced BRAF mutant melanoma treatment efficacy by inhibiting the STAT3/SOX2 signaling pathway by Xing Luo, Yi Duan, Jinwei He, CongGai Huang, Jun Liu, Yifan Liu, Mengdei Xu, Qiong Dai, Zhihui Yang

“…The diameter and weight of tumours in each group were then measured, and IHC and HE staining were used to assess the expression of two pathways and cytotoxicity, respectively.ResultsThis study found that DHT directly interacts with STAT3 protein and it can stop the feedback activation of the STAT3/SOX2 pathway caused by the use of MAPK pathway inhibitors. …”
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Longitudinal performance trajectories for youth female and male soccer players: 10m-sprint percentile curves adapted to biological age by Julia Hernandez, Chantal Widmer, Stephen Cobley, Dennis-Peter Born, Wolfgang Taube, Michael Romann

“…To estimate biological age, the Mirwald test was used, with 18’748 measurements utilized for the analysis. These data were extracted from the Swiss Football Association’s online database, covering the period from 2014, respectively 2019 to 2024. …”
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Spatial distribution and influencing factors of secondhand smoke exposure in Chinese healthcare facilities: a cross-sectional survey by Ying LIU, Xinying ZENG, Lin XIAO, Shiwei LIU

“…ObjectiveTo understand the spatial distribution and influencing factors of secondhand smoke (SHS) exposure in healthcare facilities in China, and to provide a reference for the development of regional tobacco control strategies and measures in these facilities. MethodsData were collected from the 2022 China Adult Tobacco Survey, including relevant data from non-collectively residing Chinese residents aged ≥ 15 years old and above in 31 provinces (autonomous regions, municipalities) across the country. …”
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Nissen-Sleeve procedure versus laparoscopic Roux-en-Y gastric bypass in patients with morbid obesity and gastro-oesophageal reflux disease: protocol for a non-inferiority randomise... by Jan A Apers, Martin Dunkelgrun, Ivonne Leeuwenburgh, Judith W H 't Hart, Bo J Noordman, Laser U Biter

“…Absence of GORD is defined as &lt;8 points on the GORD questionnaire. Secondary outcome measures are long-term GORD improvement; failure rate of procedure; health-related quality of live; weight loss; proton pump inhibitor use; postoperative complications &lt;30 days and &gt;30 days; length of hospital stay; duration of primary surgery; effect on comorbidities; presence and grade of oesophagitis (grade A–D) and/or presence of Barrett’s oesophagus and cost-effectiveness.Ethics and dissemination The protocol was approved by the Medical Research Ethics Committees United (MEC-U), Nieuwegein, on 15 September 2021. …”
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Leucocytosis and Asymptomatic Urinary Tract Infections in Sickle Cell Patients at a Tertiary Hospital in Zambia by Taonga Musonda, Mildred Zulu, Mulemba Samutela, Annie Kalonda, Hamakwa Mantina, Pauline Okuku, Musalula Sinkala, Panji Nkhoma

“…We found that all the measured patients’ haemoglobin (Hb) levels fell below the WHO-recommended reference range with a minimum of 5 g/dl, a maximum of 10.5 g/dl, and a mean of 8 ± 1 g/dl. …”
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Effectiveness of a Videoconference-Based Cognitive Behavioral Therapy Program for Patients with Schizophrenia: Pilot Randomized Controlled Trial by Masayuki Katsushima, Hideki Nakamura, Yuki Shiko, Hideki Hanaoka, Eiji Shimizu

“…The primary outcome was the Positive and Negative Syndrome Scale (PANSS) total score, which measures the difference in the mean change from baseline (week 0) to posttest (week 8). …”
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Effects of metabolizable energy intake and body weight restriction on layer pullets: 2 - Body composition and onset of lay by Thiago L. Noetzold, Jo Ann Chew, Douglas R. Korver, René P. Kwakkel, Laura Star, Martin J. Zuidhof

“…Weight of reproductive organs were measured only in Experiment 2. Data were submitted to ANOVA on each experiment with the two main effects and age as fixed factors. …”
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Effectiveness and safety of metformin in 51 675 patients with type 2 diabetes and different levels of renal function: a cohort study from the Swedish National Diabetes Register by Katarina Eeg-Olofsson, Soffia Gudbjörnsdottir, Ann-Marie Svensson, Björn Eliasson, Linus Schioler, Björn Zethelius, Nils Ekström, Jan Cederholm, Junmei Miao Jonasson

“…Objective To evaluate the effectiveness and safety of metformin use in clinical practice in a large sample of pharmacologically treated patients with type 2 diabetes and different levels of renal function.Design Observational study between July 2004 and December 2010, mean follow-up 3.9 years.Setting Hospital outpatient clinics and primary care in Sweden.Participants 51 675 men and women with type 2 diabetes, registered in the Swedish National Diabetes Register, and on continuous glucose-lowering treatment with oral hypoglycaemic agents (OHAs) or insulin.Main outcome measures Risks of cardiovascular disease (CVD), all-cause mortality and acidosis/serious infection, associated with each treatment regimens, were analysed in all patients and in subgroups with different estimated glomerular filtration rate (eGFR) intervals. …”
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Effect of Staggered vs. Simultaneous Co-Administration of Bempedoic Acid on Pharmacokinetics of Pravastatin: Randomized, Cross-Over Clinical Trial in Healthy Volunteers by Felicitas Stoll, Salvatore Amato, Max Sauter, Jürgen Burhenne, Johanna Weiss, Walter E. Haefeli, Antje Blank

“…After a baseline visit with pravastatin alone, BA was dosed to steady state at the approved oral dose of 180 mg. Outcome measures were the area under the plasma concentration–time curve, extrapolated to infinity (AUC_∞) and C_max of pravastatin, 3α-hydroxy-pravastatin (pravastatin 3-iso), and pravastatin lactone, and their geometric mean ratios (GMRs) of different schedules of administration. …”
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Providing a General Model for the Successful Implementation of Digital Transformation in Organizations by Haidar Ahmadi, Najme Parsaei, Seyyed Hamed Hashemi, Hamidreza Nematollahi

“…Key factors identified include leadership and vision, which are essential for creating an enabling environment for digital transformation; change management, which is necessary for coordinating and instituting changes within the organization; collaboration and partnership, which are critical for fostering integration and connectivity between departments; user-centered design, which is vital for engaging employees and customers; and maintaining robust privacy and data security measures, which are indispensable for establishing trust in digital interfaces. …”
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Effect of Implant Positions and Angulations on Retentive Strength of 2-Implant Mandibular Overdentures: An In Vitro Study with the New 3D-Printed Simulation Method by Pravinkumar G. Patil, Liang Lin Seow, Rashmi Uddanwadikar, Allan Pau, Piyush D. Ukey

“…A total of 4 simulated overdenture model sets for each of the 10 study groups were subjected to the universal testing machine thrice to measure a peak load (N) to disengage the attachments vertically. …”
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Ultrasonic Assisted Environmentally Friendly Extraction of Natural Dyes From Beta vulgaris for the Coloration of Silk Fabric Using Different Mordants by Rony Mia, Tafsir Uddin, A. Z. M. Mofasser, Nadim Ibn Sayed, Al Mojnun Shamim, Sanjida Islam, Khandaker Akil Mahadi Ohi, Moonis Ali Khan, Burhan Uddin Banna

“…The values of color intensity (K/S), CIE L* a* b*, and CIE L* c* h* were measured using a reflectance spectrophotometer. At the same time, dry and wet rubbing and lightfastness ratings of dyed silk fabrics were determined according to the ISO standards. …”
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Effects of Alzheimer’s disease plasma marker levels on multilayer centrality in healthy individuals by Alejandra García-Colomo, David López-Sanz, Ignacio Taguas, Martín Carrasco-Gómez, Carlos Spuch, María Comis-Tuche, Fernando Maestú

“…Abstract Background Changes in amyloid beta (Aβ) and phosphorylated tau brain levels are known to affect brain network organization but very little is known about how plasma markers can relate to these measures. We aimed to address the relationship between centrality network changes and two plasma pathology markers: phosphorylated tau at threonine 231 (p-tau231), a proxy for early Aβ change, and neurofilament light chain (Nfl), a marker of axonal degeneration. …”
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How does the first index mode of birth in public or private hospitals predict subsequent births? A 16-year Australian population-based linked data study by Soo Downe, Hannah G Dahlen, Ank de Jonge, Lilian Peters, Michiel de Boer

“…For those with 2 births and 3 births, 16 and 64 subsequent births patterns were created.Primary and secondary outcome measures Trend of index modes of birth and subsequent modes of birth over time and the prediction of subsequent birth modes based on the index birth. …”
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EFFECT OF GLOMUS MOSSEAE, AZOTOBACTER CHROOCOCCUM AND VERMICOMPOST TEA ON SOME RHIZOSPHERE CHARACTERS AND MYCORRHIZAL DEPENDENCY OF CUCUMBER PLANTS by Z. H. Al-Rawi, J. S. Alkobaisy

“…The length and weight of the root system, the number of bacteria, the percentage of root infection with Mycorrhiza fungus, and the mycorrhizal dependency of the root system, vegetative and yield were measured. The results proved that the use of mycorrhiza, acetobacter bacteria, and phosphate rock with half mineral recommendation (MAR) and spraying of vermicompost tea at a concentration of 10% are the best significantly in increasing dry weight and height of the root system and in increasing the number of total bacteria. …”
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The effect of hindrance stressors on the emotional exhaustion among front-line healthcare workers in the recuperation period during the COVID-19 epidemic in China: a prospective cr... by Hua Zhang, Huan Wang, Junying Ye, Hao Wu, Xinyao Zhou, Caiping Song, Pengpeng Yin, Renzhong Shi, Yang Dan

“…Exclusion criteria included recently affected by major events other than COVID-19 or those with a history of neurasthenia and trauma.Results Using descriptive analysis of average value and SD measured by a five-item scale (MBI-GS), we found that front-line healthcare workers’ emotional exhaustion score (2.45±0.88) was at the medium level. …”
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