Reverse Shoulder Arthroplasty Baseplate Stability Is Affected by Bone Density and the Type and Amount of Augmentation by Daniel Ritter, Patric Raiss, Patrick J. Denard, Brian C. Werner, Manuel Kistler, Celina Lesnicar, Micheal van der Merwe, Peter E. Müller, Matthias Woiczinski, Coen A. Wijdicks, Samuel Bachmaier

“…Biomechanical testing included cyclic loading in an articulating setup, with optical pre- and post-cyclic micromotion measurements in a rocking horse setup. Results: There were no differences in bone density between groups based on CT scans (<i>p</i> > 0.126). …”
Get full text

Anti-Inflammatory and Healing Activity of the Hydroalcoholic Fruit Extract of Solanum diploconos (Mart.) Bohs by Larissa Benvenutti, Roberta Nunes, Ivonilce Venturi, Silvia Aparecida Ramos, Milena Fronza Broering, Fernanda Capitanio Goldoni, Sarah Eskelsen Pavan, Maria Verônica Dávila Pastor, Angela Malheiros, Nara Lins Meira Quintão, Elizabeth Soares Fernandes, José Roberto Santin

“…Inflammation resolution was measured by the efferocytosis assay and the healing activity by in vivo and in vitro assays. …”
Get full text

High HDL-C and high LDL-C are risk factors of pterygium in a population-based cross-sectional study in Southern China: the Dongguan Eye Study by Liang Zhang, Min Zhang, Ying Cui, Lixin Zhang, Guanrong Zhang, Qingyang Liu, Haike Guo, Qianli Meng, Siwen Zang, Chun-Han Lo, Yanlei Chen, Jin Zeng

“…Objectives To investigate the relationship between serum lipids and pterygium in a large-scale rural population aged 40 years or older from Southern China.Study design The Dongguan Eye Study was a cross-sectional population-based study from September 2011 to February 2012.Setting The area was set in the rural area of Dongguan, Southern China.Participants Adult rural population aged 40 or older.Methods Participants underwent physical, haematological and ophthalmic examinations.Primary and secondary outcome measures The frequency and risk factors of pterygium.Results A total of 11 357 participants were eligible for inclusion and 8952 (78.8%) participants were enrolled for the systemic and ophthalmic examinations. …”
Get full text

Variations in Water Stress and Its Driving Factors in the Yellow River Basin by Haodong Lyu, Jianmin Qiao, Gonghuan Fang, Wenting Liang, Zidong Tang, Furong Lv, Qin Zhang, Zewei Qiu, Gengning Huang

“…In response to the national strategy of ecological protection and high-quality development of the Yellow River Basin, as well as Sustainable Development Goal 6.4 (SDG 6.4), we applied the water stress index (WSI) to measure water stress in the basin. This analysis utilized land use datasets, socio-economic datasets, irrigation datasets, water withdrawal/consumption datasets, and runoff datasets from 2000 to 2020. …”
Get full text

Identifying strokes in Nigerian children with sickle cell disease as part of clinical trials: training curriculum for healthcare professionals in low-income settings by Djamila L. Ghafuri, Halima Bello-Manga, Fenella J. Kirkham, Mariana Ciobanu, Edwin Trevathan, Edwin Trevathan, Mark Rodeghier, Michael R. DeBaun, Michael R. DeBaun, Lori C. Jordan

“…We describe our health professional stroke training curriculum and specific application to detect strokes in clinical trials in low-resource settings.MethodsChildren aged 5–12 and 2–16 years with SCA in northern Nigeria were enrolled in the SPRING and SPRINT primary and secondary stroke prevention trials, respectively. The primary outcome measure in both trials was a clinical stroke based on the World Health Organization definition. …”
Get full text

Dissection of the genetic loci for grain hardness and variation of the key genes in common wheat (Triticum aestivum L.) by Jinna Hou, Pengge Sun, Pei Yan, Shenghui Geng, Wenxu Li, Maomao Qin, Ziju Dai, Baoming Tian, Zhengqing Wu, Zhengfu Zhou, Changwen Li, Zhensheng Lei

“…In the present study, an association population consisted with 207 wheat accessions was planted across three years and the grain hardness index (GHI) of each accession was measured. The genetic loci associated with GHI were dissected based on a high-throughput SNPs map through genome-wide association study (GWAS). …”
Get full text

The prevalence of malaria in the five districts of Limpopo Province, South Africa, 2015 - 2017 by M T Lamola, A Musekiwa, A de Voux, C Reddy, M Morifi, P C Mutevedzi

“…We estimated the prevalence of malaria, and the proportion of imported malaria cases in the five districts of Limpopo, from January 2015 to December 2017. Objective. To measure the prevalence of malaria in Limpopo Province, the proportion of malaria cases that are imported and to determine factors associated with malaria from January 2015 to December 2017. …”
Get full text

Impact of witnessing abuse of their mother and childhood trauma on men's perpetration of intimate partner violence in the cross-sectional UN multi-country study on men and violence... by Rachel Jewkes, Ruchira Tabassum Naved, Naeema Abrahams, Nwabisa Shai, Leane Ramsoomar, Bianca Dekel, Andrew Gibbs, Jani Nöthling, Samantha Willan, Esnat Chirwa

“…Paths were mediated by food insecurity, depression, and a latent variable measuring gender inequitable and anti-social masculinities. …”
Get full text

Multi-Isotope Geochemical Baseline Study of the Carbon Management Canada Research Institutes CCS Field Research Station (Alberta, Canada), Prior to CO2 Injection by Rachel E. Utley, Emma Martin-Roberts, Nicholas Utting, Gareth Johnson, Domokos Györe, Marta Zurakowska, Finlay M. Stuart, Adrian J. Boyce, Thomas H. Darrah, Pauline Gulliver, R. Stuart Haszeldine, Don Lawton, Stuart M. V. Gilfillan

“…Importantly, 4He concentrations in all gas samples lie on a mixing line between the atmosphere and the elevated 4He concentration present in a hydrocarbon well sampled from a reservoir located below the Field Research Station (FRS) implying a diffusive or advective crustal flux of 4He at the site. In contrast, the measured 4He concentrations in shallow groundwaters at the site are much lower and may be explained by gas loss from the system or in situ production generated by radioactive decay of U and Th within the host rocks. …”
Get full text

Network Meta-Analysis and Trial Sequential Analysis of Randomised Controlled Trials Comparing Robotic, Laparoscopic, and Open Pancreatoduodenectomy by Nejo Joseph, MBChB, Chris Varghese, MBChB, James Lucocq, MBChB, Matthew J. McGuinness, MBChB, Samuel Tingle, MBChB, Giovanni Marchegiani, PhD, Kjetil Soreide, PhD, Mohammed Abu-Hilal, Jas Samra, Marc Besselink, PhD, Steve White, Sanjay Pandanaboyana, FRCS

“…However, few studies demonstrated robust statistical significance in outcome measures, suggesting an underpowered evidence base and possible selection bias. …”
Get full text

Exploring urban-rural inequalities of maternal healthcare utilization in Bangladesh by A.T.M. Shariful Alam, Shorful Alam, Kashfia Mobasshira, S.M. Nuruzzaman Anik, Mohammad Nayeem Hasan, Muhammad Abdul Baker Chowdhury, Md Jamal Uddin

“…Additionally, the Wagstaff decomposition method measures the concentration index, elasticity, contribution, and percentage contributions of different factors. …”
Get full text

Associations between WASH-related violence and depressive symptoms in adolescent girls and young women in South Africa (HPTN 068): a cross-sectional analysis by Ruvani T Jayaweera, Kathleen Kahn, Sheri A Lippman, Torsten B Neilands, Rhian Twine, Jennifer Ahern, Ryan G Wagner, Audrey Pettifor, Dana Goin

“…Lifetime experience of violence or fear of violence when using the toilet and collecting water was collected by self-report; depressive symptoms in the past week were measured using the Center for Epidemiological Studies Depression Scale (CES-D). …”
Get full text

Lung function improvement on triple modulators: high-resolution, nationwide data from the Danish Cystic Fibrosis Cohort by Christian Leo-Hansen, Daniel Faurholt-Jepsen, Tavs Qvist, Christine Højte, Bibi U. Nielsen, Thomas Bryrup, Esben H. Henriksen, Terese Katzenstein, Marianne Skov, Inger H.M. Mathiesen, Majbritt Jeppesen, Søren Jensen-Fangel, Hanne V. Olesen, Frederik Fouirnaies Buchvald, Kim Gjerum Nielsen, Espen Jimenez-Solem, Christian Ritz, Tacjana Pressler, Mette F. Olsen, the TransformCF Study Group

“…Results We included 392 people living with cystic fibrosis with a median (interquartile range) 12 (nine to 15) spirometry measurements per person. The mean (95% CI) improvement in ppFEV1 was 13.0 (11.3–14.6) 12 months after initiation of elexacaftor/tezacaftor/ivacaftor treatment. …”
Get full text

Mobile application adjunct to the WHO basic emergency care course: a mixed methods study by Juma A Mfinanga, Hendry R Sawe, Anya L Greenberg, Andrea G Tenner, Alexandra Friedman, Paulina Nicholaus, Christian C Rose, Newton Addo, Catherine Reuben Shari, Upendo N George, Michael J Losak

“…We assessed whether a mobile application adjunct (BEC app) can have positive impact on knowledge acquisition and retention compared with the BEC course alone and evaluated perceptions, acceptability and barriers to adoption of such a tool.Design Mixed-methods prospective cohort study.Participants Adult healthcare workers in six health facilities in Tanzania who enrolled in the BEC course and were divided into the control arm (BEC course) or the intervention arm (BEC course plus BEC app).Main outcome measures Changes in knowledge assessment scores, self-efficacy and perceptions of BEC app.Results 92 enrolees, 46 (50%) in each arm, completed the BEC course. 71 (77%) returned for the 4-month follow-up. …”
Get full text

Nature and Origin of Mineralizing Fluids in Hyperextensional Systems: The Case of Cretaceous Mg Metasomatism in the Pyrenees by Benoît Quesnel, Marie-Christine Boiron, Michel Cathelineau, Laurent Truche, Thomas Rigaudier, Gérard Bardoux, Pierre Agrinier, Michel de Saint Blanquat, Emmanuel Masini, Eric C. Gaucher

“…Stable isotope analyses (δ13C, δ18O, δD, and δ37Cl) and Cl/Br ratio measurements in fluid inclusions and their host minerals were carried out in order to determine the origin of the fluid(s) involved in the formation of the ore deposit. …”
Get full text

Effectiveness of an electronic clinical decision support system in improving the management of childhood illness in primary care in rural Nigeria: an observational study by Marek Kwiatkowski, Rodolfo Rossi, Torsten Schmitz, Fenella Beynon, Capucine Musard, Marco Landi, Daniel Ishaya, Jeremiah Zira, Muazu Muazu, Camille Renner, Edwin Emmanuel, Solomon Gideon Bulus

“…Intervention and control facilities received supportive supervision based on the national supervision protocol.Primary and secondary outcome measures The primary outcome was caregiver-reported recovery at day 7, collected over the phone. …”
Get full text

Prevalence, risk factors and associated ocular diseases of cerebral stroke: the population-based Beijing Eye Study by Jost B Jonas, Ya Xing Wang, Liang Xu, Wen Bin Wei

“…Objective To assess the prevalence of cerebral stroke in the general population of Beijing and its association with systemic risk factors and ocular diseases.Setting The population-based Beijing Eye Study was conducted in a rural and urban region of Beijing.Participants With eligibility criteria of age 50+ years and living in the study regions, 3468 subjects (78.8%) out of 4403 eligible individuals participated.Primary and secondary outcome measures The study participants underwent a detailed systemic and ophthalmological examination and an interview in which the occurrence of a previous stroke was assessed.Results A previous stroke was reported by 235 individuals (7.33%; 95% CI 6.43% to 8.24%). …”
Get full text

ANO7 expression in the prostate modulates mitochondrial function and lipid metabolism by Christoffer Löf, Nasrin Sultana, Neha Goel, Samuel Heron, Gudrun Wahlström, Andrew House, Minna Holopainen, Reijo Käkelä, Johanna Schleutker

“…Results ANO7 expression resulted in the downregulation of metabolic pathways, particularly genes associated with the MYC pathway and oxidative phosphorylation (OXPHOS) in both prostate tissue and ANO7-expressing cells. Measurements of OXPHOS and glycolysis in the ANO7-expressing cells revealed a metabolic shift towards glycolysis. …”
Get full text

The Influence of Vitamin D Levels and Supplementation on the Treatment of Patients Affected by MRONJ by Filip Michalak, Marzena Dominiak, Jan Kiryk, Paweł Popecki, Dominik Kubicki, Jacek Matys, Kinga Grzech-Leśniak

“…Vitamin D levels were measured at baseline, 3 months, and 6 months, and the relationship between vitamin D supplementation and clinical outcomes, including MRONJ risk and healing, was evaluated. …”
Get full text

A comparative study of the effect of capsular repair in the Latarjet procedure by Andrew P. McBride, Thibault Lafosse, Alex N. Karanja, Laurent Lafosse, Ian P. Hughes, Gregory A. Hoy, Eugene T. Ek, Shane A. Barwood, Fraser Taylor, Ezekiel Tan

“…Range of motion was measured using a Proteck goniometer. Clinical outcomes were assessed using the Western Ontario Shoulder Instability Index (WOSI), Oxford shoulder, Oxford instability, Walch-Duplay and Rowe scores. …”
Get full text