Cross-cultural validation and reference norms for the DCDDaily-Q questionnaire Chinese version (DCDDaily-Q-CN): evaluating children’s motor performance in activities of daily livin... by Meihuan Huang, Yujun Zhan, Haishan Zhou, Ping Song, Yanping Fan, Yang Lu, Yijing Chen, Zhen Lv, Qing Liu, Guojun Yun, Jianguo Cao

“…The total performance score effectively differentiated between children with DCD and controls (U = 9.0, p < 0.001), with a cutoff score of 45, demonstrating a sensitivity of 93% (95%CI: 77–99%) and specificity of 90% (95%CI: 74–98%).ConclusionThe findings support that the DCDDaily-Q-CN is a reliable and valid measure to assess participation and performance in motor-based ADLs and fulfill criterion B of the diagnostic criteria for DCD.…”
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The Interactive Effects of Fruit Intake Frequency and Serum miR-484 Levels as Biomarkers for Incident Type 2 Diabetes in a Prospective Cohort of the Spanish Adult Population: The D... by Ana Lago-Sampedro, Wasima Oualla-Bachiri, Cristina Maldonado-Araque, Sergio Valdés, Inmaculada González-Molero, Viyey Doulatram-Gamgaram, Elias Delgado, Felipe J. Chaves, Luis Castaño, Alfonso Calle-Pascual, Josep Franch-Nadal, Gemma Rojo-Martínez, Sara García-Serrano, Eva García-Escobar

“…Baseline serum miR-484 levels were measured using real-time qPCR and categorized based on the 25th percentile. …”
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Changes in African lion demography and population growth with increased protection in a large, prey‐depleted ecosystem by Scott Creel, Matthew S. Becker, Ben Goodheart, Anna Kusler, Kachama Banda, Kambwiri Banda, Milan Vinks, Catherine Sun, Chase Dart, Stephi Matsushima, Ruth Kabwe, Will Donald, Luka Zyambo, Peter Indala, Adrian Kaluka, Clive Chifunte, Craig Reid

“…Here, we used an integrated population model to test whether lion demography and population dynamics were measurably improved by increased protection. We used data from monitoring of 358 individuals from 2013 to 2021 in the Greater Kafue Ecosystem, where prior research showed that lions were strongly limited by prey depletion, but protection increased in several well‐defined areas beginning in 2018. …”
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The CD4/CD8 ratio is associated with T lymphocyte functions in long-term virally suppressed patients with HIV by Qing Xiao, Fengting Yu, Liting Yan, Xiaojie Lao, Xuelei Liang, Hongxin Zhao, Liuyue Zhai, Zailin Yang, Xiaomei Zhang, Yao Liu, Fujie Zhang

“…The activation and proliferation phenotypes, mitochondrial functions, and inflammatory indexes of CD4+ T cells and CD8+ T cells were measured, and correlations between the CD4/CD8 ratio and T cell functions were analyzed. …”
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Paucity of viral infection symptoms in patients with immune-mediated inflammatory diseases by Carola Berking, Georg Schett, Andreas Ramming, Raja Atreya, Markus F Neurath, Bernhard Manger, Filippo Fagni, Arnd Kleyer, Milena L Pachowsky, Axel J Hueber, Stefan Kleinert, Karin Manger, Florian Schuch, Monika Ronneberger, David Simon, Michael Sticherling, Koray Tascilar, Christine Meder, Moritz Leppkes, Peter Dietrich, Verena Schoenau, Daniela Bohr, Fabian Hartmann, Selahattin Alp Temiz, Ioanna Minopoulou, Louis Schuster, Melek Yalcin Mutlu, Gerhard Kroenke, Till Orlemann, Johanna Mößner

“…This study aimed to investigate the symptom pattern of common viral infections in patients with IMID and compare it with controls without IMIDs.Design A cross-sectional study conducted between 1 February and 30 April 2020, using a questionnaire.Setting Seven tertiary regional care centers in Germany, which specialised in the care of patients with IMID (namely, in gastroenterology, dermatology, rheumatology and immunology clinical care).Participants One thousand nine hundred nine participants completed the survey (757 patients with IMID; 1152 non-IMID controls).Primary outcome measure The occurrence of 11 common viral illness symptoms within the preceding 3 months in patients with IMID and non-IMID controls.Results Symptom data were clustered, based on number and co-occurrance, into 3 major clusters and 2 subclusters ranked by the average number of symptoms. …”
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Effects on impulsivity and delay discounting of intermittent theta burst stimulation add-on to dialectical behavioral therapy in borderline personality disorder: a randomized, sham... by Milenko Kujovic, Christian Bahr, Mathias Riesbeck, Daniel Benz, Martina Deiß, Zsofia Margittai, Sebastian Henges, Dirk Reinermann, Christian Plewnia, Eva Meisenzahl

“…Results A mixed model repeated measures analysis with a 2 × 2 factorial between-subjects design showed a significant overall improvement over time in impulsivity but not in decision-making/delay discounting. …”
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Development of a zoonotic influenza distribution assessment and ranking system (ZIDAR): Technical application in Nepal to support cross-sectoral risk-based surveillance by Adam Charette-Castonguay, Dipendra Gautam, Binay Shrestha, Hemant Chandra Ojha, Barun Kumar Sharma, Mukul Upadhayaya, Sujan Rana, Roshika Shrestha, Lok Bandu Chaudhary, Bhawana Kandel, Rudra Prasad Marasini, Sharmila Chapagain, Tulsi Ram Gompo, Surendra Karki, Apsara Poudel, Saugat Shrestha, Avinash Sunny Kayastha, Arun Kumar Govindakarnavar, Reuben Samuel, Allison Gocotano, Pushpa Ranjan Wijesinghe, Nilesh Buddha, Edwin Ceniza Salvador, Manish Kakkar, Ricardo J. Soares Magalhães

“…Here, we introduce the development and application of a Zoonotic Influenza Distribution and Ranking (ZIDAR) framework to identify areas highly suitable for zoonotic influenza transmission across multiple exposure interfaces and to measure the importance of associated risk factors. …”
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Protocol for a feasibility study and process evaluation of a psychosocially modelled diabetes education programme for young people with type 1 diabetes: the Youth Empowerment Skill... by Nick Sevdalis, Khalida Ismail, Tayana Soukup, Trevor Murrells, Dulmini Kariyawasam, Stephen Thomas, Judith Parsons, Angus Forbes, Rita Forde, Maria Baldellou Lopez, Marie Jones, Martha Ford-Adams, Nardos Yemane, Siobhan Pender, Alex Silverstien

“…Study findings will be used to optimise the intervention components, outcome measures and recruitment methods to inform a subsequent definitive trial.Ethics and dissemination The protocol has ethical approval from the UK Health Research Authority (approval IRAS project ID: 279877). …”
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Predictive value of CT-based and AI-reconstructed 3D-TAPSE in patients undergoing transcatheter tricuspid valve repair by Johannes Kirchner, Muhammed Gerçek, Hazem Omran, Kai Peter Friedrichs, Felix Rudolph, Tobias Rossnagel, Misagh Piran, Arseniy Goncharov, Maria Ivannikova, Volker Rudolph, Tanja Katharina Rudolph

“…In multivariate Cox regression, posterior iTAPSE was found to be a significant predictor of outcome 1 year after TTVI.ConclusionsPosterior iTAPSE is an independent predictor of cardiovascular outcomes among patients undergoing TTVI. Furthermore, CT-measured TAPSE has incremental value and refines risk stratification for clinical outcomes in patients undergoing TTVI.…”
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Medical insurance-related professionals’ identification of the benefits of the medical insurance system in Northeast China: a cross-sectional study by Zili Zhou, Huan Liu, Linghan Shan, Ye Li, Xin Zhang, Jiahui Wang, Zheng Kang, Mingli Jiao, Yanhua Hao, Yangguang Chen, Qunhong Wu

“…Government departments can pay closer attention to these factors and formulate targeted intervention measures to improve the implementation effectiveness of medical insurance policies.…”
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Reductive acetogenesis is a dominant process in the ruminant hindgut by Qiushuang Li, Jiabin Huo, Gaofeng Ni, Fan Zhang, Shizhe Zhang, Xiumin Zhang, Rong Wang, Jinzhen Jiao, Zhongtang Yu, Xuanxuan Pu, Yipeng Yue, Emilio M. Ungerfeld, Xiaoli Zhang, Jian Wu, Zhiliang Tan, Chris Greening, Min Wang

“…Results To address this gap, we comparatively investigated the composition, capabilities, and activities of the rumen and the cecum microbiome using goats as an experimental ruminant model. In situ measurements showed significantly higher levels of dissolved hydrogen and acetate in the cecum than in the rumen. …”
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Nicotine dependence is associated with an increased risk of developing chronic, non-communicable inflammatory disease: a large-scale retrospective cohort study by Khalaf Kridin, Khalaf Kridin, Khalaf Kridin, Cristian Papara, Katja Bieber, David A. De Luca, Jan Philipp Klein, Marlene A. Ludwig, Philip Curman, Philip Curman, Philip Curman, Philip Curman, Artem Vorobyev, Astrid Dempfle, Ralf J. Ludwig

“…The sex-stratified analysis revealed few sex-specific differences in CID risk.DiscussionOur study emphasizes the importance of preventive measures targeting nicotine addiction to reduce the global burden of CIDs.…”
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Exploring the Impact of the Multimodal CAPABLE eHealth Intervention on Health-Related Quality of Life in Patients With Melanoma Undergoing Immune-Checkpoint Inhibition: Prospective... by Itske Fraterman, Lucia Sacchi, Henk Mallo, Valentina Tibollo, Savannah Lucia Catherina Glaser, Stephanie Medlock, Ronald Cornet, Matteo Gabetta, Vitali Hisko, Vadzim Khadakou, Ella Barkan, Laura Del Campo, David Glasspool, Alexandra Kogan, Giordano Lanzola, Roy Leizer, Manuel Ottaviano, Mor Peleg, Konrad Śniatała, Aneta Lisowska, Szymon Wilk, Enea Parimbelli, Silvana Quaglini, Mimma Rizzo, Laura Deborah Locati, Annelies Boekhout, Lonneke V van de Poll-Franse, Sofie Wilgenhof

“…MethodsThis prospective pilot study compared an exploratory cohort that received the CAPABLE smartphone app and a multisensory smartwatch for 6 months (intervention) to a 2:1 individually matched historical prospective control group. HRQoL data were measured with the European Organization for Research and Treatment of Cancer Quality of Life Questionnaire-Core 30 at baseline (T0), 3 months (T1), and 6 months (T2) after start of treatment. …”
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Azithromycin Promotes the Osteogenic Differentiation of Human Periodontal Ligament Stem Cells after Stimulation with TNF-α by Tingting Meng, Ying Zhou, Jingkun Li, Meilin Hu, Xiaomeng Li, Pingting Wang, Zhi Jia, Liyu Li, Dayong Liu

“…Western blotting was used to measure the NF-κB signaling pathway proteins p65, phosphorylated p65, IκB-α, phosphorylated IκB-α, and β-catenin as well as the apoptosis-related proteins caspase-8 and caspase-3. …”
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Extracellular acyl-CoA-binding protein as an independent biomarker of COVID-19 disease severity by Stephane Isnard, Stephane Isnard, Tsoarello Mabanga, Tsoarello Mabanga, Léna Royston, Léna Royston, Léna Royston, Carolina A. Berini, Carolina A. Berini, Simeng Bu, Simeng Bu, Orthy Aiyana, Orthy Aiyana, Hansen Feng, Hansen Feng, Bertrand Lebouché, Bertrand Lebouché, Bertrand Lebouché, Bertrand Lebouché, Cecilia T. Costiniuk, Cecilia T. Costiniuk, Joseph Cox, Joseph Cox, Guido Kroemer, Guido Kroemer, Guido Kroemer, Madeleine Durand, Jean-Pierre Routy, Jean-Pierre Routy, Jean-Pierre Routy, the Biobanque Québécoise de la COVID-19 (BQC-19)

“…Levels of anti-SARS-CoV-2 IgG were measured by ELISA and a cell-binding assay.ResultsThe median age of the participants was 59 years, 46% were female, 65% had comorbidities. …”
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Affective valence predictors from real-world based short sprint interval training by Stefano Benítez-Flores, Flávio A. de S. Castro, Eduardo Caldas Costa, Daniel Boullosa, Todd A. Astorino

“…These findings suggest that HR-based measures, particularly those related to in-task stress (time ≥ 90% HRpeak) and acute recovery (ΔHRRend-120s end, and RMSSDend), may predict affective valence during real-world sSIT.…”
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Association of handgrip strength asymmetry and weakness with intrinsic capacity impairment among older adults in China by Decheng Li, Yunhe Wang, Shuai Guo, Ziyang Ren, Binbin Su, Lichuan Zhang, Zuliyaer Talifu, Xiaoying Zheng

“…Asymmetry and weakness were measured using the maximum value of HGS. Logistic regression models were employed to examine the association of the individual and combined groupings of HGS asymmetry and weakness with IC impairment (a total score ≥ 2 across five domains). …”
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Determination and prediction of the apparent and standardized ileal amino acid digestibility in soybean meal fed to the pullets by Sumei Cao, Yuxin Yang, Guangtian Ma, Jing Wang, Kai Qiu, Zhigang Song, Shugeng Wu, Guanghai Qi, Haijun Zhang

“…This experiment was conducted to evaluate the chemical composition, apparent ileal digestibility (AID) and standardized ileal digestibility (SID) of amino acid (AA) in 10 different sources of soybean meal (SBM) fed to the pullets and established prediction equations based on the chemical composition of SBM. 792 Hy Line Brown hens aged 12-15 weeks were divided into 11 diet groups, the diets included one nitrogen-free diet (NFD) used to measure the basal endogenous losses of AA and 10 SBM test diets containing 35.2 % SBM as the sole source of AA. …”
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Examining the association between public health unit spending and adolescent substance use by Urvi Rai, Karen A. Patte, Brendan T. Smith, Ambikaipakan Senthilselvan, Elaine Hyshka, Scott T. Leatherdale, Roman Pabayo

“…The sample included 29,056 students in grades 9–12 attending 61 secondary schools in 15 PHUs across Ontario. Substance use was measured as the self-reported use of alcohol, cannabis, cigarettes and e-cigarettes, at least once per month on average. …”
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Geographical equity in Ethiopian infant feeding practices: a secondary analysis of a birth cohort study by Solomon Shiferaw, Joanna Schellenberg, Kassahun Alemu Gelaye, Tanya Marchant, Della Berhanu, Atkure Defar, Meseret Zelalem, Amare Tariku, Lars Persson, Zewditu Abdissa Denu, Seblewengel Lemma, Theodros Getachew Zemedu, Tadesse Guadu Delele, Girum Taye Zeleke

“…We performed geographically weighted regression to investigate whether sociodemographic factors explained the geographical feeding differences.Participants 1850 infants were prospectively followed from birth to 12 months.Outcome measures Exclusive breastfeeding at 5 months and minimum-level dietary diversity at 12 months.Results Sixty-nine percent (95% CI 67 to 71) of infants were exclusively breastfed at 5 months, while at 12 months, only 16% (95% CI 13 to 19) had complementary feeding from five or more food groups. …”
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