The influence of monosodium glutamate on the development of oxidative-nitrosative stress in the large cerebral hemispheres of rats under the combination of a change in the “light-d... by O. A. Volkova, O. Ye. Akimov, V. O. Kostenko

“…The aim of the work was to find out the influence of monosodium glutamate on the development of oxidative-nitrosative stress in the homogenate of the large cerebral hemispheres of rats with a combination of acute desynchronosis (AD), SIR and administration of monosodium glutamate. Material and methods. The research was carried out on 72 white Wistar rats weighing 150–200 of different sexes, divided into 5 groups: control (n = 15), AD (n = 13), SIR (n = 15), a combination of SIR and AD (n = 14), a combination of SIR, AD, and glutamate (n = 15). …”
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Investigation of antioxidant capacity in farmed beluga (Huso huso) fingerling fed with Echinacea purpurea and garlic (Allium sativum) powder extracts by Soheil Bazari Moghadam, Forouzan Bagherzadeh Lakani, Jalil Jalilpoor, Mehdi Masoumzadeh

“…So, this study was performed to evaluate the effects of two types of powdered extract Echinacea and garlic on antioxidant capacity of farmed beluga Huso huso during a two-month period. Materials and methods: A total of 210 fish with an average weight of 27.74 ± 0.26 g were randomly placed in twenty one 500-L fiberglass tanks, and fed with basal diet supplemented with powder extracts in seven treatments (with three replications) including control (without adding garlic and E. purpurea), treatment 1 = 250 mg/kg garlic, treatment 2 = 500 mg/kg garlic, treatment 3 = 1000 mg/kg garlic, treatment 4 = 250 mg/kg E. purpurea, treatment 5 = 500 mg/kg E. purpurea, treatment 6 = 1000 mg/kg E. purpurea for 8 weeks. …”
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Sustainability assessment of animal feed production from by-products of Sago palm smallholder industry by Allaily ., A.D. Santoso, M.N. Rofiq, N.A. Sasongko, H. Daulay, E.I. Wiloso, E. Widjaja, B.N. Utomo, A.I. Yanuar, S. Suryani, Y.P. Erlambang, U.N. Thiyas, D. Iskandar, A. Anhar, M. Rahmawati, T. Simamora, Y. Yusriani, G. Maghfirah, M. Ammar

“…BACKGROUND AND OBJECTIVES: Sago plant is a valuable source of raw material for the processing industry and every part is very useful for food and shelter. …”
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Alterations in the polarization of liver M1/M2 macrophages upon long-term administration of triptorelin in rats by M.V. Rud, Y.V. Stetsuk, V.I. Shepitko, O.V. Vilkhova, L.B. Pelypenko, O.V. Voloshyna, A.G. Sydorenko, H.P. Pavlenko, N.M. Sharlai, O.V. Sych

“…The study employed a series of experimental periods, with the introduction of triptorelin and quercetin at varying stages. Materials and methods. The study was conducted on 35 sexually mature male rats. …”
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Altered Topological Properties of Grey Matter Structural Covariance Networks in Complete Thoracic Spinal Cord Injury Patients: A Graph Theoretical Network Analysis by Wen-Li Wang, Yu-Lin Li, Mou-Xiong Zheng, Xu-Yun Hua, Jia-Jia Wu, Fei-Fei Yang, Nan Yang, Xia He, Li-Juan Ao, Jian-Guang Xu

“…This study is aimed at investigating brain structural changes and structural network properties in complete spinal cord injury (SCI) patients, as well as their relationship with clinical variables. Materials and Methods. Structural MRI of brain was acquired in 24 complete thoracic SCI patients (38.50±11.19 years, 22 males) within the first postinjury year, while 26 age- and gender-matched healthy participants (38.38±10.63 years, 24 males) were enrolled as control. …”
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Acinetobacter baumannii infection in critically ill patients with COVID-19 from Tehran, Iran: the prevalence, antimicrobial resistance patterns and molecular characteristics of iso... by Mahsa Ghamari, Fereshteh Jabalameli, Shirin Afhami, Shahnaz Halimi, Mohammad Emaneini, Reza Beigverdi

“…This study aimed to determine the prevalence, antimicrobial resistance patterns, presence of selected antimicrobial resistance genes, and genetic diversity of A. baumannii isolates obtained from COVID-19 cases admitted to the ICU at the University Hospital in Iran.Materials and methodsThis was a cross-sectional and single-center study comprising patients with A. baumannii infections admitted to the ICU with COVID-19 between April and November 2021. …”
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Comparison of Intraoperative and Postoperative Outcomes of Sleeve and Dorsal Slit Technique of Circumcision: A Prospective Interventional Study by N Snigdha, R Lakshmana, Das Debarath, Natarjan Soorya, A Pravindhas, M Malar Mannan

“…Aim: To compare the intraoperative and postoperative outcomes of the dorsal slit technique and sleeve technique of circumcision. Materials and Methods: A prospective interventional study was conducted at SRM Medical College Hospital and Research Centre, Chennai, Tamil Nadu, India from October 2022 to April 2024. …”
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Assessment of Learning Styles of First-year Medical Students’ using VARK 8.02 Model Questionnaire: A Cross-sectional Study by Senthil Ganesh P Kannappan, Ravichandran Doraisamy, Vijayakumar Jagadesan

“…Aim: To evaluate the learning styles of first-year MBBS students in a private medical college in Tamil Nadu India, identify the prevalence of unimodal and multimodal learners, and examine the correlation of learning styles between genders. Materials and Methods: A descriptive cross-sectional questionnaire survey was conducted among first-year MBBS students at Sri Venkateswaraa Medical College in Tamil Nadu, India from January 2024 to March 2024. …”
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Confocal Microscopy for Detection of Intracellular Bacteria in Urine Samples of patients Suspected with Urinary Tract Infection: A Cross-sectional Observational Study by Bhagyashri Patil-Takbhate, Nilam Memane, Srikanth Tripathy, Nageswari Gandham, Shahzad Mirza

“…Aim: To study the presence of ICB in exfoliated urothelial cells using confocal microscopy. Materials and Methods: A cross-sectional observational study was conducted at Dr. …”
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Development of Cephradine-Loaded Gelatin/Polyvinyl Alcohol Electrospun Nanofibers for Effective Diabetic Wound Healing: In-Vitro and In-Vivo Assessments by Anam Razzaq, Zaheer Ullah Khan, Aasim Saeed, Kiramat Ali Shah, Naveed Ullah Khan, Bouzid Menaa, Haroon Iqbal, Farid Menaa

“…LNF-based therapy could be employed as a valuable dressing material to heal <i>S. aureus</i>-induced chronic wounds in diabetic subjects.…”
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Development and usability testing of a multifaceted intervention to reduce low-value injury care by Mélanie Bérubé, Alexandra Lapierre, Michael Sykes, Jeremy Grimshaw, Alexis F. Turgeon, François Lauzier, Monica Taljaard, Henry Thomas Stelfox, Holly Witteman, Simon Berthelot, Éric Mercier, Catherine Gonthier, Jérôme Paquet, Robert Fowler, Natalie Yanchar, Barbara Haas, Paule Lessard-Bonaventure, Patrick Archambault, Belinda Gabbe, Jason R. Guertin, Yougdong Ouyang, Lynne Moore, the Canadian Traumatic Brain Injury Research Consortium

“…Accordingly, the following intervention strategies were selected: involving governing structures and leaders, distributing audit & feedback reports on performance, and providing educational materials, de-implementation support tools and educational/facilitation visits. …”
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Biological activities of Usnea lethariiformis lichen extracts and UHPLC-ESI-QTOF-MS analysis of their secondary metabolites by Mauricio Piñeiro, Mauricio Piñeiro, Sofía Manrique, Jessica Gómez, Jessica Gómez, Juan Manuel Rodriguez, Patricia Barrera, Duilio Caballero, Miguel A. Sosa, Gabriel Vargas-Arana, Gabriel Vargas-Arana, Alejandro Tapia, Beatriz Lima, Beatriz Lima, Mario J. Simirgiotis

“…The air-dried U. lethariiformis material was extracted successively with dichloromethane and methanol (UlMeOH). …”
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Promoting trans patient autonomy in surgical preparation for phalloplasty and metoidioplasty: results from a community-based cross-sectional survey and implications for preoperativ... by Leo L. Rutherford, Elijah R. Castle, Noah Adams, Logan Berrian, Linden Jennings, Ayden Scheim, Aaron Devor, Nathan J. Lachowsky

“…Across surgical disciplines, a variety of resources are used to assist patients who are preparing for surgeries, including educational materials, workshops, peer support, and lifestyle changes. …”
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Safety and efficacy of telaprevir in treatment of a chronic hepatitis C in patients of the Russian population included in early access program study by D. T. Abrurakhmanov, V. G. Morozov, I. G. Nikitin, P. O. Bogomolov, N. I. Geyvandova, Ye. N. Bessonova, I. G. Bakulin, V. A. Isakov, K. V. Zhdanov, M. V. Mayevskaya, Ye. A. Nurmukhametova, E. Z. Burnevich, Ye. V. Chesnokov, V. D. Pasechnikov, A. Hill, I. Lonjon-Domanec, S. N. Kizhlo

“…Efficacy and safety of this therapeutic mode were evaluated in intermediate analysis on 16-th week of treatment in 153 patients from Russia who have already reached the 16-th week of treatment or potentially can do so.Material and methods. The study has prospectively included 153 HCV infected patients (genotype 1), with bridging fibrosis or compensated liver cirrhosis who received treatment by telaprevir in combination to peginterferon-alpha and ribavirin for 12 wks with subsequent 12-or 36-week rate of antiviral therapy (AVT) by peginterferon alpha and ribavirin in relation to virologic response and fibrosis severity. …”
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Interleukin-12 Inhibits Tumor Growth and Metastasis Promoted by Tumor-Associated Mesenchymal Stem Cells in Triple-Negative Breast Cancer by Babak Jahangiri, Zahra-Soheila Soheili, Elahe Asadollahi, Mehdi Shamsara, Vahid Shariati, Alireza Zomorodipour

“…Objective: The aim of this study was to understand the interactions between tumor-associated mesenchymal stemcells (TA-MSCs) and triple-negative breast cancer (TNBC) cells, which appear to be necessary for developing effectivetherapies.Materials and Methods: In this experimental study, MDA-MB-231 and 4T1 TNBC cells were co-cultured with bonemarrow-derived MSCs, and TA-MSCs conditioned media (CM) were collected. …”
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Functional Characteristics and Lipid Lowering Activity of Auricularia heimuer Soluble Dietary Fiber by Xueyu SHANG, Heriban MEI, Ling SU, Qi WANG

“…In this study, the residue of Auricularia heimuer polysaccharide after hot water extraction was used as raw material, and the soluble dietary fiber (HSDF) of A. heimuer was extracted by compound enzyme method. …”
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Immunomodulatory Effects of Combination Therapy with Bushen Formula plus Entecavir for Chronic Hepatitis B Patients by Long-Shan Ji, Qiu-Tian Gao, Ruo-Wen Guo, Xin Zhang, Zhen-Hua Zhou, Zhuo Yu, Xiao-Jun Zhu, Ya-Ting Gao, Xue-Hua Sun, Yue-Qiu Gao, Man Li

“…To compare the clinical efficacy of the combination therapy with Bushen formula (BSF) plus entecavir (ETV) in naïve chronic hepatitis B (CHB) patients and that in CHB patients with partial virological response to ETV and explore the relevant immunoregulatory mechanism. Materials and Methods. Two hundred and twenty CHB patients were enrolled in the historical prospective cohort study. …”
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Association between serum albumin and severe impairment of activities of daily living in patients with stroke: a cross-sectional study by Ranran Bi, Yupeng Shi, Manrong Li, Xiaochen Liu, Zhenchao Ma, Yiqing Huang, Bingyin Liang, Fang Cui

“…This study aims to provide further results.Materials and methodsThis study examined cross-sectional data from patients aged 18 years or older with a diagnosis of stroke confirmed by cranial CT or MRI within 24 h of admission, gathered from January 2020 to August 2022. …”
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Simultaneous Debridement and Titanium Mesh Reconstruction in Patients with Compound Depressed Skull Fracture: A Retrospective Descriptive Study by Srikant Das, Acharya Suryakant Pattajoshi, Mahesh Kumar Kusta, Dibakar Sarkar

“…Aim: To analyse the results of single-stage titanium mesh reconstruction in the management of compound and comminuted skull fractures. Materials and Methods: This was a retrospective descriptive study in the Neurosurgery Department at Veer Surendra Medical Sciences and Research (VIMSAR), Burla, Sambalpur, Odisha, India, from January 2018 to June 2023 and consisting of case records of 98 patients with head injuries associated with compound skull fractures who were admitted. …”
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CD44-Receptors-Mediated Multiprong Targeting Strategy Against Breast Cancer and Tumor-Associated Macrophages: Design, Optimization, Characterization, and Cytologic Evaluation by Hussain Z, Abdulrahim Abdul Moti L, Jagal J, Thu HE, Khan S, Kazi M

“…In this research, we aimed to design a multiprong targeting strategy for concurrent action against different phenotypes of BC (MCF-7 and SK-BR-3) and tumor-associated macrophages (TAMs) for relapse-free treatment of BC.Methods: Paclitaxel (PTX) and tamoxifen (TMX) co-loaded chitosan (CS) nanoparticles (NPs) were prepared using the ionic-gelation method and optimized using the Design Expert® software by controlling different material attributes. For selective targeting through CD44-receptors that are heavily expressed on the BC cells and TAMs, the fabricated NPs (PTX-TMX-CS-NPs) were functionalized with hyaluronic acid (HA) as a targeting ligand.Results: The optimized HA-PTX-TMX-CS-NPs exhibited desired physicochemical properties (PS ~230 nm, PDI 0.30, zeta potential ~21.5 mV), smooth spherical morphology, high encapsulation efficiency (PTX ~72% and TMX ~97%), good colloidal stability, and biphasic release kinetics. …”
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