The Frequency of Exfoliation Syndrome in the Central Anatolia Region of Turkey by Raşit Kılıç, Hafize Sezer, Sebile Ü. Çomçalı, Serdar Bayraktar, Gökay Göktolga, Yasin Çakmak, Abdi B. Çetin, Tongabay Cumurcu

“…A significant relationship was found between exfoliation syndrome and glaucoma, cataracts, age-related macular degeneration, and phacodonesis. While no relationship was found between exfoliation syndrome and hypertension or diabetes mellitus, a significant relationship was found with coronary artery disease. …”
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Keratoacanthoma of the Nasal Septum Secondary to Ranibizumab Use by Jason E. Cohn, Hilary M. Caruso Sales, Giang Huong Nguyen, Harvey Spector, Kenneth Briskin

“…Additionally, this patient was taking ranibizumab, a vascular endothelial growth factor (VEGF) inhibitor for macular degeneration. Despite ranibizumab not being directly linked to precancerous and cancerous skin lesions, agents in this medication class have been. …”
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Human Factors Studies to Assess the Usability of the Faricimab Prefilled Syringe by Barakat MR, Kwong Jr HM, Marcon G, O'Leary OE, Paris LP, Schneider P, Tang Y, Graff JM

“…., San Francisco, CA, USA; 6Barnet Dulaney Perkins Eye Center, Phoenix, AZ, USA; 7Ophthalmology Division, Creighton University School of Medicine, Phoenix, Arizona, USACorrespondence: Jordan M Graff, Barnet Dulaney Perkins Eye Center, Phoenix, AZ, USA, Tel +1 480 843 1868, Email JGraff@BDPEC.comPurpose: Faricimab, the first bispecific antibody designed for intraocular use, is approved for the treatment of neovascular age-related macular degeneration (nAMD), diabetic macular edema (DME), and retinal vein occlusion (RVO). …”
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Effect of intravitreal injections on the progression and prognosis of primary open-angle glaucoma by A.B. Movsisyan, N.G. Glazko, A.Yu. Brezhnev, A.V. Kuroyedov

“…Mandryka Military Clinical Hospital, Moscow, Russian Federation</b> </p> <p> <i>Intravitreal injections (IVI) have revolutionized management strategies for many disorders, e.g., age-related macular degeneration (AMD), diabetic macular edema, retinal vein occlusion, choroidal inflammatory diseases, and pathologic myopia. …”
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The Mitochondria-Targeted Antioxidant SkQ1 Downregulates Aryl Hydrocarbon Receptor-Dependent Genes in the Retina of OXYS Rats with AMD-Like Retinopathy by M. L. Perepechaeva, A. Yu. Grishanova, E. A. Rudnitskaya, N. G. Kolosova

“…It has been shown that SkQ1 reduces clinical signs of retinopathy in senescence-accelerated OXYS rats, which are a known animal model of human age-related macular degeneration (AMD). The aim of this work was to test whether SkQ1 affects transcriptional activity of AhR (aryl hydrocarbon receptor) and Nrf2 (nuclear factor erythroid 2-related factor 2), which are considered as AMD-associated genes in the retina of OXYS and Wistar rats. …”
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Rho-Kinase/ROCK as a Potential Drug Target for Vitreoretinal Diseases by Muneo Yamaguchi, Shintaro Nakao, Mitsuru Arima, Iori Wada, Yoshihiro Kaizu, Feng Hao, Shigeo Yoshida, Koh-hei Sonoda

“…Vitreoretinal diseases including diabetic retinopathy, age-related macular degeneration, and proliferative vitreoretinoapthy are still a major cause of blindness. …”
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Global, regional, and national burden of blindness and vision loss attributable to smoking from 1990 to 2021, and forecasts to 2030: findings from the Global Burden of Disease Stud... by Yi Zeng, Yixian Liu, Xingyi Chen, Jennifer Kenny, Rong Rong, Xiaobo Xia

“…Methods We extracted data on years lived with disability (YLDs) and age-standardized YLDs rate (ASYR) related to blindness and vision loss (BVL) caused by smoking, including cataracts and age-related macular degeneration (AMD), from the Global Burden of Disease (GBD) database for the years 1990 to 2021. …”
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Association of arterial stiffness and eye disease: a systematic review and meta-analysis by Robert Scragg, Angela L Beros, John D Sluyter

“…Background This systematic review and meta-analysis assesses the association of arterial stiffness with age-related macular degeneration (AMD), glaucoma, retinal vein occlusion (RVO) and retinopathy (diabetic and hypertensive).Methods Medline and Embase were systematically searched for observational studies of arterial stiffness and eye disease. …”
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Detection Rate and Diagnostic Value of Optical Coherence Tomography Angiography in the Diagnosis of Polypoidal Choroidal Vasculopathy: A Systematic Review and Meta-Analysis by Yuelin Wang, Jingyuan Yang, Bing Li, Mingzhen Yuan, Youxin Chen

“…This study aimed to evaluate the detection rate of polyps and branching vascular networks (BVNs) in polypoidal choroidal vasculopathy (PCV) by optical coherence tomography angiography (OCTA) and assess the sensitivity and specificity of OCTA in differentiating PCV from wet age-related macular degeneration (wAMD). Materials and Methods. …”
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Essential Role of Thioredoxin 2 in Mitigating Oxidative Stress in Retinal Epithelial Cells by Eriko Sugano, Namie Murayama, Maki Takahashi, Kitako Tabata, Makoto Tamai, Hiroshi Tomita

“…Disruption of these systems leads to the development of age-related macular degeneration. Thioredoxin 2 (Trx2) is a potent antioxidant, which acts directly on mitochondria. …”
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From botany to bedside: a review of the health benefits of Lycium barbarum as a functional food by Alois Berisha, Elena-Alexandra Alexa, Robbie Kelleher, Tao Zhang

“…Furthermore, its role in addressing age-related macular degeneration and chronic conditions such as cancer and metabolic syndrome is highlighted. …”
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Drug Screening of Flavonoids as Potential VEGF Inhibitors Through Computational Docking and Cell Models by Shengying Lin, Roy Wai-Lun Tang, Yutong Ye, Chenxi Xia, Jiahui Wu, Ran Duan, Ka-Wing Leung, Tina Ting-Xia Dong, Karl Wah-Keung Tsim

“…Vascular endothelial growth factor (VEGF), also known as VEGF-A, has been linked to various diseases, such as wet age-related macular degeneration (wAMD) and cancer. Even though there are VEGF inhibitors that are currently commercially available in clinical applications, severe adverse effects have been associated with these treatments. …”
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Acute-Onset Vitreous Hemorrhage of Unknown Origin before Vitrectomy: Causes and Prognosis by Dong Yoon Kim, Soo Geun Joe, Seunghee Baek, June-Gone Kim, Young Hee Yoon, Joo Yong Lee

“…Among these, retinal vein occlusion (RVO), retinal break, and age-related macular degeneration (AMD) were identified in 74 (43.8%), 50 (29.6%), and 21 (12.4%) patients, respectively. …”
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iPSC-Derived Retinal Pigment Epithelium Allografts Do Not Elicit Detrimental Effects in Rats: A Follow-Up Study by Peter D. Westenskow, Felicitas Bucher, Stephen Bravo, Toshihide Kurihara, Daniel Feitelberg, Liliana P. Paris, Edith Aguilar, Jonathan H. Lin, Martin Friedlander

“…Photoreceptors rely heavily on the RPE, and death or dysfunction of RPE is characteristic of age-related macular degeneration (AMD), a very common neurodegenerative disease for which no cure exists. …”
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Association of dietary inflammatory index with ocular diseases: a population-based cross-sectional study by Xue Wang, Can Zhang, Haitao Jiang

“…Abstract Background Our research was designed to investigate the relationship between dietary inflammatory index (DII) and risk of ocular diseases, including glaucoma, cataract, age-related macular degeneration (ARMD), and diabetic retinopathy. …”
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Repeated exposure to low doses of light induces retinal damage in vivo in a wavelength-dependent manner by Anaïs Françon, Laurent Jonet, Francine Behar-Cohen, Alicia Torriglia

“…However, meta-analyses pointed out the role of lifelong light exposure in the onset of age-related macular degeneration, suggesting a cumulative effect of light exposure. …”
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Promiscuous Chemokine Antagonist (BKT130) Suppresses Laser-Induced Choroidal Neovascularization by Inhibition of Monocyte Recruitment by Shira Hagbi-Levi, Michal Abraham, Liran Tiosano, Batya Rinsky, Michelle Grunin, Orly Eizenberg, Amnon Peled, Itay Chowers

“…Background. Age-related macular degeneration (AMD), the most common cause of blindness in the developed world, usually affects individuals older than 60 years of age. …”
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Clinical experience with recombinant prourokinase for complex retinal diseases in type 2 diabetes by L.K. Moshetova, Yu.B. Slonimsky, I.V. Vorobyeva, A. Dgebuadze, O.V. Agafonova, E.P. Delver, A.A. Belogurov

“…., diabetic retinopathy, hypertensive retinopathy, “wet” age-related macular degeneration (AMD) with hemorrhages in type 2 diabetes) using recombinant prourokinase by dynamic retinal changes and tear levels of vascular endothelial growth factor (VEGF-A).…”
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High-coverage whole-genome sequencing of a Jakun individual from the “Orang Asli” Proto-Malay subtribe from Peninsular Malaysia by Wai-Sum Yap, Alvin Cengnata, Woei-Yuh Saw, Thuhairah Abdul Rahman, Yik-Ying Teo, Renee Lay-Hong Lim, Boon-Peng Hoh

“…Some of these variants are associated with age-related macular degeneration, atrial fibrillation, and HDL cholesterol level. …”
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میزان سرب خون در بیماران مبتلا به دژنراسیون ماکولا وابسته به سن by مینا پولادوند, مصطفی فقهی, محمد ملک احمدی, فریدون فرهی, زهرا رمضانی, علی شهسواری, پردیس تولائی نژاد

“…مقاله پژوهشیمقدمه: هدف از این مطالعه، ارزیابی سطح سرب خون در بیماران مبتلا به دژنراسیون ماکولا وابسته به سن (Age-related macular degeneration ) AMD بود.روش‌ها: این مطالعه‌ی مورد- شاهدی، بر روی بیماران مبتلا به AMD و افراد سالم در شهر اهواز استان خوزستان در ایران انجام شد. …”
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