Effectiveness and tolerability of the combined use of anti-VEGF agents in clinical practice by A.V. Kuroyedov, O.V. Gapon’ko, V.V. Gorodnichiy, S.V. Diordiychuk, I.V. Kondrakova, N.M. Sol’nov, N.E. Fomin

“…</i> </p> <p> <i><b>Keywords</b>: age-related macular degeneration, anti-VEGF drugs, intravitreal administration, IOP level, aflibercept, ranibizumab.…”
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The Efficacy of Conbercept in Polypoidal Choroidal Vasculopathy: A Systematic Review by Yimin Wang, Mengxi Shen, Jinwei Cheng, Xiaodong Sun, Peter K. Kaiser

“…The use of antivascular endothelial growth factor (VEGF) therapy in polypoidal choroidal vasculopathy (PCV), a subtype of neovascular age-related macular degeneration (nAMD), has been well established in randomized clinical trials. …”
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Potential guidelines for cataract surgery and rehabilitation in visually impaired patients: Literature analysis by Paolo Giuseppe Limoli, Celeste Limoli, Marcella Nebbioso

“…The most common causes of low vision include age‐related macular degeneration (AMD), high myopia (HM), diabetic retinopathy (DR), glaucoma (GL), and inherited degenerative ocular diseases. …”
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RatDNA: DATABASE ON MICROARRAY STUDIES OF RATS BEARING GENES ASSOCIATED WITH AGE-RELATED DISEASES by O. S. Kozhevnikova, M. K. Martyschenko, M. A. Genaev, E. E. Korbolina, N. A. Muraleva, N. G. Kolosova, Y. L. Orlov

“…People do not die of «healthy» aging: at any age conditions whose probability increases with age become the cause of their death. Age-related macular degeneration (AMD) becomes the main cause of vision problems and sight loss in people aged above 50. …”
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Visual, Musculoskeletal, and Balance Complaints in AMD: A Follow-Up Study by Christina Zetterlund, Hans Olof Richter, Lars-Olov Lundqvist

“…To investigate whether patients with age-related macular degeneration (AMD) run a potentially higher risk of developing visual, musculoskeletal, and balance complaints than age-matched controls with normal vision. …”
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Systems Biology Profiling of AMD on the Basis of Gene Expression by Mones S. Abu-Asab, Jose Salazar, Jingsheng Tuo, Chi-Chao Chan

“…Genetic pathways underlying the initiation and progression of age-related macular degeneration (AMD) have not been yet sufficiently revealed, and the correlations of AMD’s genotypes, phenotypes, and disease spectrum are still awaiting resolution. …”
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Lutein Leads to a Decrease of Factor D Secretion by Cultured Mature Human Adipocytes by Yuan Tian, Aize Kijlstra, Johan Renes, Martin Wabitsch, Carroll A. B. Webers, Tos T. J. M. Berendschot

“…Complement plays an important role in the pathogenesis of age related macular degeneration (AMD) and trials are currently being conducted to investigate the effect of complement inhibition on AMD progression. …”
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Histological Characterization of the Dicer1 Mutant Zebrafish Retina by Saeed Akhtar, Sarita Rani Patnaik, Rakesh Kotapati Raghupathy, Turki M. Al-Mubrad, John A. Craft, Xinhua Shu

“…DICER1 was recently shown to have another function of silencing the toxicity of Alu RNAs in retinal pigment epithelium (RPE) cells, which are involved in the pathogenesis of age related macular degeneration. In this study, we characterized a Dicer1 mutant fish line, which carries a nonsense mutation (W1457Ter) induced by N-ethyl-N-nitrosourea mutagenesis. …”
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Distributed training of foundation models for ophthalmic diagnosis by Sina Gholami, Fatema-E Jannat, Atalie Carina Thompson, Sally Shin Yee Ong, Jennifer I. Lim, Theodore Leng, Hamed Tabkhivayghan, Minhaj Nur Alam

“…Abstract Vision impairment affects nearly 2.2 billion people globally, and nearly half of these cases could be prevented with early diagnosis and intervention—underscoring the urgent need for reliable and scalable detection methods for conditions like diabetic retinopathy and age-related macular degeneration. Here we propose a distributed deep learning framework that integrates self-supervised and domain-adaptive federated learning to enhance the detection of eye diseases from optical coherence tomography images. …”
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3D Curvelet-Based Segmentation and Quantification of Drusen in Optical Coherence Tomography Images by M. Esmaeili, A. M. Dehnavi, H. Rabbani

“…This imaging modality can assist clinicians in monitoring the progression of Age-related Macular Degeneration (AMD) by providing high-resolution visualization of drusen. …”
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Focal Choroidal Elevations: Localized Pigment Epithelial Contour Alterations due to Isolated Choroidal Vessels by Rachel L. Chu, Nicole A. Pannullo, Eric J. Sigler

“…FCE were observed in 25 patients with age-related macular degeneration (ARMD), in 5 patients with high myopia, and in 8 patients with age-related choroidal atrophy (ARCA). …”
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ROCK Inhibitor-Induced Promotion of Retinal Pigment Epithelial Cell Motility during Wound Healing by Hiroyuki Kamao, Atsushi Miki, Junichi Kiryu

“…No standard therapy for RPE tear, a complication of neovascular age-related macular degeneration, exists even though RPE tears cause severe vision loss, and promotion of cell proliferation and/or migration could be a candidate RPE tear therapy. …”
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The Prevalence of Age-Related Eye Diseases and Cataract Surgery among Older Adults in the City of Lodz, Poland by Michal Szymon Nowak, Janusz Smigielski

“…The prevalence rates of DR and myopic macular degeneration were 1.72% (95% CI 0.95–2.48) and 0.45% (95% CI 0.06–0.85), respectively. …”
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The Frequency of Exfoliation Syndrome in the Central Anatolia Region of Turkey by Raşit Kılıç, Hafize Sezer, Sebile Ü. Çomçalı, Serdar Bayraktar, Gökay Göktolga, Yasin Çakmak, Abdi B. Çetin, Tongabay Cumurcu

“…A significant relationship was found between exfoliation syndrome and glaucoma, cataracts, age-related macular degeneration, and phacodonesis. While no relationship was found between exfoliation syndrome and hypertension or diabetes mellitus, a significant relationship was found with coronary artery disease. …”
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Photobiomodulation in ocular therapy: current status and future perspectives by Hasan Chichan, Iftkhar Hamzah Aldujaly, Konstantinos Michalakis, Levent Kanal

“…This review specifically targets the treatment of retinal diseases including age-related macular degeneration, diabetic macular edema, myopia and acute retinal light injury with photobiomodulation. …”
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Keratoacanthoma of the Nasal Septum Secondary to Ranibizumab Use by Jason E. Cohn, Hilary M. Caruso Sales, Giang Huong Nguyen, Harvey Spector, Kenneth Briskin

“…Additionally, this patient was taking ranibizumab, a vascular endothelial growth factor (VEGF) inhibitor for macular degeneration. Despite ranibizumab not being directly linked to precancerous and cancerous skin lesions, agents in this medication class have been. …”
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Postpartum Exudation of Idiopathic Quiescent Macular Neovascularization: A Narrative Review with a Related Case Report by Livio Vitiello, Maddalena De Bernardo, Ilaria De Pascale, Giulio Salerno, Alfonso Pellegrino, Nicola Rosa

“…People over 50 are often affected by this disorder, which is typically brought on by age-related macular degeneration. In addition, MNV can be found in people under 50 years of age, who may present primary ophthalmic diseases such as pathological myopia, angioid streaks, traumatic choroidal rupture, or suspected ocular histoplasmosis syndrome. …”
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Evaluation of the protective role of ellagic acid in retinal degeneration: an experimental model by Eman E. Mousa, Aziza A. Elsaied, Mohammad M. Murad, Amal E. Ibrahim

“…Group I served as the control group, while group II and group III, the macular degeneration (MD) induction groups that received a single intravitreal injection of sodium iodate (SI). …”
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The Mitochondria-Targeted Antioxidant SkQ1 Downregulates Aryl Hydrocarbon Receptor-Dependent Genes in the Retina of OXYS Rats with AMD-Like Retinopathy by M. L. Perepechaeva, A. Yu. Grishanova, E. A. Rudnitskaya, N. G. Kolosova

“…It has been shown that SkQ1 reduces clinical signs of retinopathy in senescence-accelerated OXYS rats, which are a known animal model of human age-related macular degeneration (AMD). The aim of this work was to test whether SkQ1 affects transcriptional activity of AhR (aryl hydrocarbon receptor) and Nrf2 (nuclear factor erythroid 2-related factor 2), which are considered as AMD-associated genes in the retina of OXYS and Wistar rats. …”
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Rho-Kinase/ROCK as a Potential Drug Target for Vitreoretinal Diseases by Muneo Yamaguchi, Shintaro Nakao, Mitsuru Arima, Iori Wada, Yoshihiro Kaizu, Feng Hao, Shigeo Yoshida, Koh-hei Sonoda

“…Vitreoretinal diseases including diabetic retinopathy, age-related macular degeneration, and proliferative vitreoretinoapthy are still a major cause of blindness. …”
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