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1201
Common biomarkers of idiopathic pulmonary fibrosis and systemic sclerosis based on WGCNA and machine learning
Published 2025-01-01“…Single-cell RNA sequencing (sc-RNAseq) revealed a significant difference in CCL2 expression in alveolar epithelial type 1/2 cells, mast cells, ciliated cells, club cells, fibroblasts, M1/M2 macrophages, monocytes and plasma cells between IPF patients and healthy donors. …”
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1202
Antigen-Induced Immunomodulation in the Pathogenesis of Atherosclerosis
Published 2008-01-01“…Atherosclerosis is a chronic inflammatory disorder characterised by the accumulation of monocytes/macrophages, smooth muscle cells, and lymphocytes within the arterial wall in response to the release of proinflammatory molecules. …”
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1203
Effect of an inhaled glucocorticoid on reactive oxygen species production by bronchoalveolar lavage cells from smoking COPD patients
Published 2000-01-01“…Apparently, heavy smoking impaired the ability of alveolar macrophages to produce ROS, which was not further decreased by FP.…”
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1204
Visfatin Amplifies Cardiac Inflammation and Aggravates Cardiac Injury via the NF-κB p65 Signaling Pathway in LPS-Treated Mice
Published 2022-01-01“…Visfatin expression levels in both the heart and serum were increased in LPS-treated mice and peaked at 6 hours, and visfatin was derived from cardiac macrophages. In septic mice, pretreatment with visfatin reduced the survival rate, worsened cardiac dysfunction, and increased the expression of cardiac injury markers, including creatine kinase myocardial bound (CK-MB) and lactate dehydrogenase (LDH). …”
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1205
Proinflammatory Stimuli Enhance Phagocytosis of Apoptotic Cells by Neutrophil Granulocytes
Published 2011-01-01“…Recently, we have reported that, in addition to macrophages, also neutrophil granulocytes can phagocytose apoptotic neutrophils. …”
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1206
Role of astrocytes and microglia in hepatic encephalopathy associated with advanced chronic liver disease: lessons from animal studies
Published 2025-12-01“…Microglia, the brain resident macrophages, have been linked to the translation of systemic inflammation to the brain microenvironment. …”
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1207
Construction of a Cuprotosis-Related Gene-Based Model to Improve the Prognostic Evaluation of Patients with Gastric Cancer
Published 2022-01-01“…The plasma cells, monocytes, and mast cells in GC tissue were significantly less than those in adjacent tissue (p<0.05), while T cell CD4 memory activated macrophage M0, macrophage M1, and macrophages in GC tissue. …”
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1208
Crotoxin Isolated from Crotalus durissus terrificus Venom Modulates the Functional Activity of Dendritic Cells via Formyl Peptide Receptors
Published 2018-01-01“…Formyl peptide receptors (FPRs) and lipoxin A4 (LXA4) are involved in CTX’s effect on macrophages and neutrophils. Dendritic cells (DCs) are plasticity cells involved in the induction of adaptive immunity and tolerance maintenance. …”
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1209
Control of Intracellular Francisella tularensis by Different Cell Types and the Role of Nitric Oxide
Published 2014-01-01“…Here we assess the role of nitric oxide in control of intracellular infections in two murine macrophage cell lines of different provenance: the alveolar macrophage cell line, MH-S, and the widely used peritoneal macrophage cell line, J774A.1. …”
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1210
An Improved Yolov10n for Detection of Bronchoalveolar Lavage Cells
Published 2025-01-01“…This study presents an improved Yolov10 method for the detection and classification of BALF cells, specifically targeting macrophages, lymphocytes, neutrophils, and eosinophils. …”
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1211
Effect of innate and induced immunity on infectious bursal disease pathogenesis
Published 2023-09-01“…The infectious bursal disease virus (IBDV) affects chicken’s immune system in a comprehensive and integrated manner thus destructing B-lymphocytes, attracting T-cells and activating macrophages. Being the RNA-virus, the agent is specified by high frequency of mutations, which result in the emergence of the strains with modified antigenicity and increased virulence. …”
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1212
Curcumin mimics of potential chemoprevention with NQO1 induction properties
Published 2025-01-01“…LPS-induced iNOS production in RAW264.7 macrophages of the most promising agents discovered (5ab and 5ac) displayed concentration-dependent with comparable activities to the reference anti-inflammatory drug indomethacin. …”
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1213
The effect of nuclear transcriptional factor κВ activation inhibitor – curcumine on the experimental immune liver disease
Published 2010-02-01“…At Т-cellular hepatitis cytolytic component of liver lesion, primary and secondary cell necrosis, depression of cytophagous activity of macrophages that causes preconditions for enhancement of inflammation were more intensive. …”
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1214
Insulin Resistance, Inflammation, and Obesity: Role of Monocyte Chemoattractant Protein-1 (orCCL2) in the Regulation of Metabolism
Published 2010-01-01“…This coordination requires a complex relationship between cells, hormones, and cytokines in which inflammatory and metabolic pathways are convergent at multiple levels. Recruitment of macrophages to metabolically compromised tissue is a primary event in which chemokines play a crucial role. …”
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1215
Morphological Changes in the Bone Marrow of the Dogs with Visceral Leishmaniasis
Published 2014-01-01“…Possibly, the bone marrow dysplasia may arise from the presence of many parasitized and activated macrophages in this organ. Consequently, it affects the profile of hematopoietic cells in the bone marrow and systemic circulation.…”
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1216
Sickle Cell Disease Activates Peripheral Blood Mononuclear Cells to Induce Cathepsins K and V Activity in Endothelial Cells
Published 2012-01-01“…Cathepsins are powerful elastases and collagenases secreted by endothelial cells and monocyte-derived macrophages in atherosclerosis, but their involvement in sickle cell disease has not been studied. …”
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1217
Proteomic Profiling and Functional Analysis of B Cell-Derived Exosomes upon Pneumocystis Infection
Published 2022-01-01“…Also, the effects of B cell exosomes on CD4+ T cell response and phagocytic function of macrophages were clarified. Briefly, 1701 proteins were identified from B cell exosomes, and the majority of them were reported in Vesiclepedia. …”
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1218
Vaccination with an Attenuated Ferritin Mutant Protects Mice against Virulent Mycobacterium tuberculosis
Published 2015-01-01“…We previously showed that a ferritin (bfrB) mutant of M. tuberculosis has altered iron homeostasis and increased sensitivity to antibiotics and to microbicidal effectors produced by activated macrophages. Most importantly, M. tuberculosis lacking BfrB is strongly attenuated in mice, especially, during the chronic phase of infection. …”
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1219
Molecular Mechanisms Underlying Anti-Inflammatory Actions of 6-(Methylsulfinyl)hexyl Isothiocyanate Derived from Wasabi (Wasabia japonica)
Published 2012-01-01“…In this paper, we review the anti-inflammatory properties of 6-MSITC and discuss potential molecular mechanisms focusing on inflammatory responses by macrophages.…”
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1220
Salivary Metabolomics Fingerprint of Chronic Apical Abscess with Sinus Tract: A Pilot Study
Published 2019-01-01“…Chronic apical abscess (CAA) is a lesion of apical periodontitis mostly characterized by areas of liquefactive necrosis with disintegrating polymorphonuclear neutrophils surrounded by macrophages. Its presence leads to local bacterial infection, systemic inflammatory response, pain, and swelling. …”
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