A charge reversal nano-assembly prevents hepatic steatosis by resolving inflammation and improving lipid metabolism by Haoyu Wang, Sheng'e Su, Xin An, Yuan Xu, Jiacheng Sun, Mingming Zhen, Chunru Wang, Chunli Bai

“…Here we propose a charge reversal fullerene based nano-assembly to migrate hepatic steatosis via inhibiting macrophage-mediated inflammation and normalizing hepatocellular lipid metabolism in obesity mice. …”
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Contribution of cuproptosis and immune-related genes to idiopathic pulmonary fibrosis disease by Chengji Jin, Jia Li, Qiaoyu Li, Lipeng Zhang, Shaomao Zheng, Qiong Feng, Yongjie Li, Yu Zheng, Qiuli Nie, Jin Liang, Jing Wang, Jing Wang

“…The expression of the CTSG showed statistically significant differences in monocyte macrophages.ConclusionThe research methodically depicted the intricate interplay among five cuproptosis-related genes, four immune-related hub genes, and IPF, offering new ideas for diagnosing and treating patients with IPF.…”
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Exploring biomarkers and molecular mechanisms of Type 2 diabetes mellitus promotes colorectal cancer progression based on transcriptomics by Simin Luo, Yuhong Zhu, Zhanli Guo, Chuan Zheng, Xi Fu, Fengming You, Xueke Li

“…Immune infiltration analysis suggested that its expression related to the proportion of M2 macrophages. Single-cell transcriptome analysis revealed a close association of COX11 expression with endothelial cells and macrophages. …”
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Uridine-cytidine kinase 2 is correlated with immune, DNA damage repair and promotion of cancer stemness in pan-cancer by Jinlong Tian, Yanlei Li, Yu Tong, Yuan Zhang, Tingxiao Zhao, Yao Kang, Qing Bi

“…There were significant correlations between UCK2 and T cells, monocytes, mast cells, and macrophages. Moreover, as expected, the immune checkpoint human leucocyte antigen (HLA) was found to be negatively related to UCK2. …”
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Single-cell RNA sequencing of the spleen reveals differences in Salmonella typhimurium infection mechanisms between different chicken breeds by Qi Zhang, Qiao Wang, Jumei Zheng, Jin Zhang, Gaomeng Zhang, Fan Ying, Dawei Liu, Jie Wen, Qinghe Li, Guiping Zhao

“…In addition, we found complex macrophage phenotypes during bacterial infection, with a tendency in macrophages from pro-inflammatory phenotypes (Mac-IL1B) to anti-inflammatory phenotypes (Mac-C1QC/Mac-MARCO). …”
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Screening and identification of host signaling pathways for alleviating influenza-induced production of pro-inflammatory cytokines, IP-10, IL-8, and MCP-1, using a U937 cell-based... by Si Chen, Si Chen, Yang Yu, Yue Su, Xiaoqin Lian, Lefang Jiang, Zhuogang Li, Mingxin Zhang, Yarou Gao, Haonan Zhang, Xingjian Zhu, Jiaxin Ke, Xulin Chen

“…Prior research indicates that IP-10, IL-8, and MCP-1, primarily produced by monocytes and macrophages, play a crucial role in influenza-induced inflammation. …”
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Systemic and mammary inflammation and mammary gland development of Holstein dairy cows around dry-off and calving by J. Gao, T.N. Marins, J.O.S. Calix, Z. Qi, C.G. Savegnago, A.M. Roper, M.W. Woldemeskel, J.K. Bernard, S. Tao

“…Mammary tissues collected in the early dry period had greater percentages of CD20+ B lymphocytes, CD172a+ macrophages, and neutrophils than tissues collected during late lactation. …”
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The antiarthritic effect of CBR‐470‐1 in hypoxic environment is to increase the level of NOD‐like receptor family pyrin domain containing 3 ubiquitination by decreasing phosphoglyc... by Ao Duan, Zemeng Ma, Xiaolong Shao, Zhencheng Xiong, Chaoyi Zhang, Wenzheng Liu, Guanglin Wang, Shouye Hu, Wei Lin

“…Abstract Background Hypoxia can affect the occurrence and development of inflammation in humans, but its effects on the disease progression of osteoarthritis (OA) remain unclear. Synovial macrophages play an essential role in the progression of arthritis. …”
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Lipoxin A4 yields an electrophilic 15-oxo metabolite that mediates FPR2 receptor-independent anti-inflammatory signaling by Adolf Koudelka, Gregory J. Buchan, Veronika Cechova, James P. O’Brien, Emily R. Stevenson, Crystal E. Uvalle, Heng Liu, Steven R. Woodcock, Steven J. Mullett, Cheng Zhang, Bruce A. Freeman, Stacy L. Gelhaus

“…Synthetic LXA4 showed no impact on these macrophage anti-inflammatory and repair responses. In summary, these data show an absence of macrophage LXA4 formation and receptor-mediated signaling actions of synthetic LXA4. …”
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LANCL1 as the Key Immune Marker in Neuropathic Pain by Yu Shi, XueFei Zhang, Qian Fang, Hongrui Zhan, Xianglong Wang, Xiyan Huang, Tao Fan, Wei Liu, Wen Wu

“…Cascade reactions including mast cells, macrophages, and T cells may be an important reason for the aggravation of nerve damage.…”
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Application of Bionanomaterials in Tumor Immune Microenvironment Therapy by Jiawei Wang, Yan Bao, Yandan Yao

“…In this review, we will summarize the most current researches on bionanomaterials for targeted regulation of tumor-associated macrophages, myeloid-derived suppressor cells, dendritic cells, T lymphocyte cells, and cancer-associated fibroblasts and summarize the prospects and challenges of cell-targeted therapy and clinical translational potential in a tumor immune microenvironment in cancer treatment.…”
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Regulation of Glial Cell Functions by PPAR-𝜸 Natural and Synthetic Agonists by Antonietta Bernardo, Luisa Minghetti

“…The pleiotropic effects of PPAR-𝛾 agonists are likely to be mediated by several mechanisms involving anti-inflammatory activities on peripheral immune cells (macrophages and lymphocytes), as well as direct effects on neural cells including cerebral vascular endothelial cells, neurons, and glia. …”
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Tracking Tumor Cells in Lymphatics in a Mice Xenograft Model by Magnetic Resonance Imaging by Ting Liu, Haijun Zhou, Rui Xia, Jichun Liao, Changqiang Wu, Hui Wang, Hua Ai, Feng Bi, Fabao Gao

“…Histologic findings confirmed the in vivo MRI results and revealed lymphangiogenesis, angiogenesis, infiltration of macrophages, and expression of vascular endothelial growth factor C in tumor and draining lymph nodes as well. …”
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Innate Immune Response in Kidney Ischemia/Reperfusion Injury: Potential Target for Therapy by Aleksandra Kezić, Natasa Stajic, Friedrich Thaiss

“…This innate immune response is characterized by the activity of classical cells belonging to the immune system, such as neutrophils, macrophages, dendritic cells, lymphocytes, and also tubular epithelial cells and endothelial cells. …”
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Genetic Characteristics and Research Progress of Feline Coronavirus by TAO Lingyun

“…The findings revealed that while their genome structures were fundamentally similar, differences in their ability to efficiently infect monocytes/macrophages significantly influenced their pathogenicity and transmission characteristics, with FIPV exhibiting higher virulence. …”
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Therapeutic implications for the PD-1 axis in cerebrovascular injury by James Feghali, Christopher M. Jackson

“…In myeloid cells, PD-1 stimulation induces polarization of microglia and macrophages into an anti-inflammatory, restorative phenotype. …”
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A pan-orthohantavirus human lung xenograft mouse model and its utility for preclinical studies. by Melanie Rissmann, Danny Noack, Thomas M Spliethof, Vincent P Vaes, Rianne Stam, Peter van Run, Jordan J Clark, Georges M G M Verjans, Bart L Haagmans, Florian Krammer, Marion P G Koopmans, Judith M A van den Brand, Barry Rockx

“…The different orthohantaviruses primarily targeted the endothelium, respiratory epithelium and macrophages in the human lung. A proof-of-concept preclinical study showed treatment of these mice with a virus neutralizing antibody could block Andes orthohantavirus infection and dissemination. …”
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Androgen receptor dynamics in prostate cancer: from disease progression to treatment resistance by Caihong Li, Dongkai Cheng, Peng Li

“…The tumor microenvironment, particularly interactions with cancer-associated fibroblasts (CAFs) and tumor-associated macrophages (TAMs), further complicates treatment by promoting aggressive tumor behavior and immune evasion. …”
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Significance of Hyperreflective Foci as an Optical Coherence Tomography Biomarker in Retinal Diseases: Characterization and Clinical Implications by Serena Fragiotta, Solmaz Abdolrahimzadeh, Rosa Dolz-Marco, Yoichi Sakurada, Orly Gal-Or, Gianluca Scuderi

“…Histopathological correlates of HRF are not univocal, spacing from migrating retinal pigment epithelium cells, lipid-laden macrophages, microglial cells, and extravasated proteinaceous or lipid material. …”
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Case of the Diffuse Form of Xanthogranulomatous Pyelonephritis by Tateki Yoshino, Hiroyuki Moriyama

“…Microscopic findings of the left kidney revealed infiltration of lymphocytes and lipid-laden macrophages (xanthoma cells) corresponding to XGP.…”
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