Ultramodern natural and synthetic polymer hydrogel scaffolds for articular cartilage repair and regeneration by Chun-Sheng Li, Yan Xu, Juan Li, Shu-Hao Qin, Shao-Wen Huang, Xue-Mei Chen, Yi Luo, Cheng-Tao Gao, Jian-Hui Xiao

“…Cellular scaffolds, which are among three key elements of tissue engineering, play significant roles in the repair of damaged articular cartilage by regulating cellular responses and promoting cartilage tissue regeneration. Biological macromolecules are commonly used as scaffold materials owing to their unique properties. …”
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Dynamic Change of Polymer in Rice Analogues and Its Effect on Texture Quality by Ke Zhang, Yang Tian, Chenglong Liu, Wentong Xue

“…Macromolecules will leach from the inside of rice analogues (RA) to the external environment and form escaping substances (ES) when boiling in water for a long time. …”
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Physicochemical Characteristics of Chitosan–Alginate Scaffold Containing Atorvastatin by Hananeh Hamedfar, Tayebeh Zivari-Ghader, Abolfazl Akbarzadeh, Soodabeh Davaran

“…Owing to its high porosity and swelling, the CS/ALG hydrogel crosslinked with PPT is an ideal scaffold for loading drugs, macromolecules, and cells.…”
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Study on the Interaction between Cadmium Sulphide Nanoparticles and Proteins by Resonance Rayleigh Scattering Spectra by Weiwei Zhu, Qi Wang, Dan Su

“…Below the isoelectric point, proteins such as bovine serum albumin (BSA), human serum albumin (HSA), lysozyme (Lys), hemoglobin (HGB), and ovalbumin (OVA) can bind with CdSn to form macromolecules by virtue of electrostatic attraction and hydrophobic force. …”
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Inhibited peroxidase activity of peroxiredoxin 1 by palmitic acid exacerbates nonalcoholic steatohepatitis in male mice by Wen Yin, Heng Xu, Zhonghao Bai, Yue Wu, Yan Zhang, Rui Liu, Zhangzhao Wang, Bei Zhang, Jing Shen, Hao Zhang, Xin Chen, Danting Ma, Xiaofeng Shi, Lihui Yan, Chang Zhang, Hualiang Jiang, Kaixian Chen, Dean Guo, Wenyan Niu, Huiyong Yin, Weiping J. Zhang, Cheng Luo, Xiangyang Xie

“…Abstract Reactive oxygen species exacerbate nonalcoholic steatohepatitis (NASH) by oxidizing macromolecules; yet how they promote NASH remains poorly understood. …”
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Growth Phase-Dependent Proteomes of the Malaysian Isolated Lactococcus lactis Dairy Strain M4 Using Label-Free Qualitative Shotgun Proteomics Analysis by Theresa Wan Chen Yap, Amir Rabu, Farah Diba Abu Bakar, Raha Abdul Rahim, Nor Muhammad Mahadi, Rosli Md. Illias, Abdul Munir Abdul Murad

“…Thus, the metabolism of the cells shifted from energy production in the exponential phase to the synthesis of macromolecules in the stationary phase. The resultant proteomes are essential in providing an improved view of the cellular machinery of L. lactis during the transition of growth phases and hence provide insight into various biotechnological applications.…”
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Scalable fabrication of an array-type fixed-target device for automated room temperature X-ray protein crystallography by Sarthak Saha, Yaozu Chen, Silvia Russi, Darya Marchany-Rivera, Aina Cohen, Sarah L. Perry

“…Abstract X-ray crystallography is one of the leading tools to analyze the 3-D structure, and therefore, function of proteins and other biological macromolecules. Traditional methods of mounting individual crystals for X-ray diffraction analysis can be tedious and result in damage to fragile protein crystals. …”
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Sulfated and Phosphorylated Agarose as Biomaterials for a Biomimetic Paradigm for FGF-2 Release by Aurelien Forget, V. Prasad Shastri

“…To access injectable biomaterials that can mimic such natural electrostatic interactions between soluble signals and macromolecules and mechanically tunable environments, the backbone of agarose, a thermogelling marine–algae-derived polysaccharide, was modified with sulfate, phosphate, and carboxylic moieties and the interaction and release of FGF-2 from these functionalized hydrogels was assessed by ELISA in vitro and CAM assay in ovo. …”
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Study of the Adsorption Mechanism and the Structure of Adsorbed Layers of Polyelectrolytes at the Metal Oxide/Solution Interface by S. Chibowski, M. Wiśniewska

“…The calculated concentrations of the various surface groups on ZrO 2 and Fe 2 O 3 enabled an investigation of the possible mechanism for the bonding of the studied polyelectrolytes with the surfaces of both oxides. PAA and PAM macromolecules bond with the solid surface mainly via the –OH groups of the oxides, which may interact with the carboxy groups of polyelectrolytes through hydrogen bridging. …”
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Enter the Matrix: Fibroblast-immune cell interactions shape extracellular matrix deposition in health and disease. [version 2; peer review: 1 approved, 2 approved with reservations... by Anthony Altieri, Grace V. Visser, Matthew B. Buechler

“…Fibroblasts regulate the composition of the extracellular matrix (ECM), a 3-dimensional network of macromolecules that comprise the acellular milieu of tissues. …”
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Scaffold-enabled high-resolution cryo-EM structure determination of RNA by Daniel B. Haack, Boris Rudolfs, Shouhong Jin, Alexandra Khitun, Kevin M. Weeks, Navtej Toor

“…These difficulties are compounded for small RNAs as cryo-EM is inherently more difficult for lower molecular weight macromolecules. Here we present a strategy for fusing small RNAs to a group II intron that yields high resolution structures of the appended RNA. …”
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Short-term airborne ultrasound induced cell death in tobacco cells and changed their wall components by Mahsa Sardari, Faezeh Ghanati, Hamid Mobasheri, Abazar Hajnorouzi

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New fruit waste-derived activated carbons of high adsorption performance towards metal, metalloid, and polymer species in multicomponent systems by Sylwia Kukowska, Piotr Nowicki, Katarzyna Szewczuk-Karpisz

“…It was noted that microwave heating favoured surface development and thus enhanced adsorbent ability to bind ions or macromolecules. Direct biomass activation led to higher microporosity compared to indirect (two-stage) one, whilst CO2-consuming activation increased aromaticity and hydrophobicity of the solids. …”
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Commercially Supplied Amine-Modified siRNAs May Require Ultrafiltration prior to Conjugation with Amine-Reactive Compounds by Shannen Lau, Bim Graham, Ben J. Boyd, Colin W. Pouton, Paul J. White

“…Conjugation of siRNA to macromolecules such as serum albumin has multiple potential benefits, including enhanced extravasation via albumin-mediated transcytosis across endothelial cells and reduced renal clearance. …”
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Analysis of Biomolecular Changes in HeLa Cervical Cancer Cell Line Induced by Interaction with [Pd(dach)Cl₂] by Vanja Ralić, Maja D. Nešić, Tanja Dučić, Milutin Stepić, Lela Korićanac, Katarina Davalieva, Marijana Petković

“…A spectral analysis, complemented by statistics, revealed that the Pd(II) complex considerably affected all major types of macromolecules in HeLa cells and induced structural changes in proteins through an increased formation of cross-β-sheets and causes structural rearrangement in deoxyribonucleic acid (DNA) through potential chromosome fragmentation. …”
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Effects of Maillard reaction and its product AGEs on aging and age-related diseases by Huan Peng, Yuqi Gao, Chenye Zeng, Rui Hua, Yannan Guo, Yida Wang, Zhao Wang

“…Despite certain advantages based on Maillard reaction products (MRPs) found in some food for health and storage application have appeared, however, the MR occurring in human physiological environment can produce advanced glycation end products (AGEs) by non-enzymatic modif ication of macromolecules such as proteins, lipids and nucleic acid, which could change the structure and functional activity of the molecules themselves. …”
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Testing the Performance of Various Polymeric Antiscalants for Mitigation of Sb-Rich Precipitates Mimicking Stibnite-Based Geothermal Deposits by Celal Çiftçi, Emre Karaburun, Serhat Tonkul, Alper Baba, Mustafa M. Demir, Mehmet İrfan Yeşilnacar

“…Various polymeric macromolecules have been used as antiscalants to mitigate the formation of scale. …”
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Unlocking the potential of azide-phosphine Staudinger reaction for the synthesis of poly(arylene iminophosphorane)s and materials therefrom by Tomaž Kotnik, Antoine Debuigne, Julien De Winter, Matej Huš, Albin Pintar, Sebastijan Kovačič

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Structural evolution characteristics of sulfur in coal during gold-tube thermal simulation by Liping Xue, Yuegang Tang, Shuo Gao

“…This study used a gold tube thermal simulation experiment to investigate the release of gases, the formation of free sulfur-containing compounds, and the evolution of coal macromolecules and organic sulfur structures. Results indicate that at Easy%Ro = 0.71, the drying coefficient (C1/ΣC1–5) of high-organic‑sulfur coal is significantly higher than that of low-organic‑sulfur coal. …”
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Integrated bioinformatics analysis identifies ALDH18A1 as a prognostic hub gene in glutamine metabolism in lung adenocarcinoma by Hao Ren, Deng-Feng Ge, Zi-Chen Yang, Zhen-Ting Cheng, Shou-Xiang Zhao, Bin Zhang

“…Cancer cells often exhibit an elevated dependence on glutamine for essential functions such as energy production, biosynthesis of macromolecules, and maintenance of redox balance. Moreover, altered glutamine metabolism can contribute to the formation of an immune-suppressive tumor microenvironment characterized by reduced immune cell infiltration and activity. …”
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