Identification of circRNA/miRNA/mRNA regulatory network involving (+)-catechin ameliorates diabetic nephropathy mice by Chao Chen, Dina Zhu, Shuai Zhang, Wensheng Zhang

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The Pattern of mRNA Expression Is Changed in Sinoatrial Node from Goto-Kakizaki Type 2 Diabetic Rat Heart by F. C. Howarth, M. A. Qureshi, P. Jayaprakash, K. Parekh, M. Oz, H. Dobrzynski, T. E. Adrian

“…There were many differences in expression of mRNA, and some of these differences were of particular interest. …”
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Erythromycin and clarithromycin modulation of growth factor-induced expression of heparanase mRNA on human lung cancer cells in vitro by Masahiro Sasaki, Takefumi Ito, Masayuki Kashima, Shin Fukui, Noriko Izumiyama, Akiko Watanabe, Masaaki Sano, Yosimasa Fujiwara, Mamoru Miura

“…We investigated the effect of three growth factors, plateletderived growth factor (PDGF), hepatocyte growth factor (HGF) and basic fibroblast growth factor (bFGF), on heparanase mRNA induction in lung cancer cells in vitro. In addition, we examined the effect of erythromycin (EM) and clarithromycin (CAM), which are 14-membered ring macrolide antibiotics that act as biological response modifiers, on the expression of heparanase mRNA induced by growth factors.…”
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Mining Potential Drug Targets and Constructing Diagnostic Models for Heart Failure Based on miRNA-mRNA Networks by Xiangming Fang, Rensheng Song, Jiaxing Wei, Qin Liao, Zhenhong Zeng

“…Based on the inflammation-related score, hypoxia-related score, and energy metabolism-related score, we identified key miRNA-mRNA pairs and constructed an interaction network. …”
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Induction of xenobiotic-metabolizing enzymes in hepatocytes by beta-naphthoflavone: Time-dependent changes in activities, protein and mRNA levels by Lněničková Kateřina, Skálová Lenka, Stuchlíková Lucie, Szotáková Barbora, Matoušková Petra

“…In the present study, time-dependency of the induction effect of a selective inducer on the activity, protein and mRNA levels of cytochromes P450 1A1/2 (CYP1A1/2), NAD(P)H:quinone oxidoreductase 1 (NQO1) and glutathione S-transferases (GSTA), in primary culture of rat hepatocytes was tested and evaluated. …”
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Gene expression signature of neuropathic pain: Unveiling compassion through pain genetics and genome-wide mRNA profiles by Ashok Kumar Saxena, Suman Choudhary, Geetanjali Chilkote

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Differential Expression Profiles of mRNA and Noncoding RNA and Analysis of Competitive Endogenous RNA Regulatory Networks in Nonalcoholic Steatohepatitis by Mengjia Gao, Jingxin Xin, Xiaoling Li, Ling Gao, Shanshan Shao, Meng Zhao

“…In this study, differentially expressed circular RNAs (circRNAs) were obtained by analyzing NASH-related circRNA datasets, and then, corresponding target microRNAs (miRNAs) and messenger RNAs (mRNAs) were predicted to construct a circRNA–miRNA–mRNA regulatory network. On this basis, a total of 38 circRNAs, 7 miRNAs, and 10 mRNAs were screened out. …”
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Altering the intracellular trafficking of Necator americanus GST-1 antigen yields novel hookworm mRNA vaccine candidates. by Athos Silva De Oliveira, Leroy Versteeg, Neima Briggs, Rakesh Adhikari, Maria Jose Villar, JeAnna R Redd, Peter Hotez, Maria Elena Bottazzi, Jeroen Pollet

“…After one immunization in mice, mRNA vaccines induced an earlier onset of antigen-specific antibodies compared to rNa-GST-1. …”
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lncRNA, miRNA, and mRNA of plasma and tumor-derived exosomes of cardiac myxoma-related ischaemic stroke by Lin Ma, Yu-Hua Liu, Chun Liu, Shu-Qi Wang, Jun Ma, Xiao-Qing Li, Min Ren, Ting-Ting Yang, Guang-Zhi Liu

“…Hence,we established an RNA-sequencing dataset for long non-coding RNA (lncRNA), microRNA (miRNA), and messenger RNA (mRNA) in the plasma and tumour-derived exosomes from four patients with cardiac myxoma-related ischaemic stroke (CM-IS) and six patients with cardiac myxoma without ischaemic stroke (non-IS CM). …”
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The Roles of Insulin-Like Growth Factor 2 mRNA-Binding Protein 2 in Cancer and Cancer Stem Cells by Junguo Cao, Qingchun Mu, Haiyan Huang

“…The insulin-like growth factor (IGF) 2 mRNA-binding protein (IGF2BP, IMP) family comprises three RBPs, IGF2BP1, IGF2BP2, and IGF2BP3, capable of associating with IGF2 and other transcripts and mediating their processing. …”
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Identification of MYC and STAT3 for early diagnosis based on the long noncoding RNA-mRNA network and bioinformatics in colorectal cancer by Kunhou Yao, Hao Fan, Tiancheng Yang, Can Yang, Guibin Wang, Xingwang Li, Xin-Ying Ji, Qun Wang, Shaojiang Lv, Shihao Guo

“…Bioinformatics analysis was performed to explore lncRNA-mRNA networks, leading to the identification of five potential blood biomarkers. …”
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The Expression Level of mRNA, Protein, and DNA Methylation Status of FOSL2 of Uyghur in XinJiang in Type 2 Diabetes by Jun Li, Siyuan Li, Ying Hu, Guolei Cao, Siyao Wang, Partab Rai, Xiaoli Wang, Kan Sun

“…We investigated the expression levels of both FOSL2 mRNA and protein as well as evaluating DNA methylation in the blood of type 2 diabetes mellitus (T2DM) Uyghur patients from Xinjiang. …”
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用荧光定量RT-PCR检测鼻咽癌病人外周血CK-19 mRNA的表达

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Genome-wide DNA methylation and mRNA transcription analysis revealed aberrant gene regulation pathways in patients with dermatomyositis and polymyositis by Hui Luo, Honglin Zhu, Ding Bao, Yizhi Xiao, Bin Zhou, Gong Xiao, Lihua Zhang, Siming Gao, Liya Li, Yangtengyu Liu, Di Liu, Junjiao Wu, Qiming Meng, Meng Meng, Tao Chen, Xiaoxia Zuo, Quanzhen Li, Huali Zhang, Xiangxiang Pan

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Generation of iPSCs by Nonintegrative RNA-Based Reprogramming Techniques: Benefits of Self-Replicating RNA versus Synthetic mRNA by Heidrun Steinle, Marbod Weber, Andreas Behring, Ulrike Mau-Holzmann, Christian Schlensak, Hans Peter Wendel, Meltem Avci-Adali

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Development of a Cationic Polymeric Micellar Structure with Endosomal Escape Capability Enables Enhanced Intramuscular Transfection of mRNA-LNPs by Siyuan Deng, Han Shao, Hongtao Shang, Lingjin Pang, Xiaomeng Chen, Jingyi Cao, Yi Wang, Zhao Zhao

Subjects: “…mRNA-LNP…”
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Systematic review of spontaneous reports of myocarditis and pericarditis in transplant recipients and immunocompromised patients following COVID-19 mRNA vaccination by Saad Shakir, Samantha Lane, Alison Yeomans

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Alterations in mRNA level of proteins related to redox state and mitochondria in an Alzheimer’s disease animal model: Promising targets in neuroprotection by Sylwia Żulińska, Przemysław L. Wencel, Kinga Czubowicz, Joanna B. Strosznajder

“…Then, mt-CytB and mt-Co1 (complex III and IV) mRNA levels were increased in 12- and 6-month-old AD brains, respectively. …”
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mRNA-LNP vaccines combined with tPA signal sequence elicit strong protective immunity against Klebsiella pneumoniae by Ting Huang, Siyou Che, Zheng Lv, Danrui Hao, Runyu Wang, Qinxuan Yi, Ling Mei, Yang Yuan, Hang Zou, Yidong Guo, Xinrong Wang, Yiwen Chu, Kelei Zhao

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氯沙坦对糖尿病大鼠肾组织TIMP2 mRNA 表达的影响 by 宛　霞, 黄湖辉, 李劲高

“…【目的】研究实验性糖尿病大鼠肾组织2 型金属蛋白组织抑制物(TIMP2)mRNA 表达的变化及氯沙坦对它的 影响。【方法】纯种雄性Wistar 大鼠分为3 组, 正常对照组(11 只), 糖尿病大鼠无干预组(11 只), 糖尿病大鼠氯沙坦(血管紧 张素Ⅱ1 型受体阻断剂)干预组(9 只)。…”
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