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741
Long noncoding RNA-EBIC promotes tumor cell invasion by binding to EZH2 and repressing E-cadherin in cervical cancer.
Published 2014-01-01“…We found 708 probe sets of lncRNAs increased and 836 probe sets decreased in CC tissues, while 1288 mRNA differential probe sets increased and 901 mRNA probe sets decreased. …”
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742
A Reduction in ADAM17 Expression Is Involved in the Protective Effect of the PPAR-α Activator Fenofibrate on Pressure Overload-Induced Cardiac Hypertrophy
Published 2018-01-01“…Similarly, in vitro experiments showed that fenofibrate significantly attenuated angiotensin II-induced cardiac hypertrophy and diminished ADAM17 mRNA and protein levels in primary cardiomyocytes stimulated with angiotensin II. …”
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743
Role of CTCF protein in regulating FMR1 locus transcription.
Published 2013-01-01“…CTCF depletion is also associated with FMR1-AS1 mRNA reduction. Antisense RNA, like sense transcript, is upregulated in UFM and absent in FXS cells and its splicing is correlated to that of the FMR1-mRNA. …”
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744
Gene expression of psychiatric disorder-related kinesin superfamily proteins (Kifs) is potentiated in alternatively activated primary cultured microglia
Published 2025-01-01“…We found that the relative amounts of Kif3a, Kif17, and Kif13a mRNA were potentiated in alternatively activated microglia, whereas there were no significant changes in activated microglia. …”
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745
膜型基质金属蛋白酶一1 在肝癌组织中的表达及意义
Published 2005-01-01“…【方法】应用半定量RT-PCR方法检测MT1-MMP mRNA在22例大肝癌及12例小肝癌组织中的表达;应用免疫组化方法检测MT1-MMP蛋白在53例大肝癌及40例小肝癌组织中的表达,并分析MT1-MMP蛋白表达水平与肝癌浸润、转移之间的关系。…”
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746
Bifidobacterium animalis subsp. lactis TG11 ameliorates loperamide-induced constipation in mice by modulating gut microbiota
Published 2025-01-01“…TG11 markedly upregulated mRNA expression of SCF and c-kit in colonic tissue. …”
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747
Involvement of transposable elements in neurogenesis
Published 2020-04-01“…In the memory formation, the role of the exchange of virus-like mRNA with the help of the Arc protein of endogenous retroviruses HERV between neurons has been revealed. …”
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748
Effects of atractylodin and β-Eudesmol on P-glycoprotein and Caco-2 cells permeability
Published 2025-02-01“…However, neither of the compounds were P-gp inhibitors nor modulators of the expression of MDR-1 mRNA, and P-gp function. Only a slight inhibitory effect was observed with atractylodin exposure at 160 µM for 24 hrs. …”
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749
In Vivo Hypoglycaemic Effect and Inhibitory Mechanism of the Branch Bark Extract of the Mulberry on STZ-Induced Diabetic Mice
Published 2014-01-01“…The mulberry BBE can increase the mRNA expression of the genes Ins1, Ins2 and pancreatic duodenal homeobox-1 (PDX-1) and may decrease the insulin resistance in diabetic mice. …”
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750
Distribution of Adiponectin Receptors 1 and 2 in the Rat Olfactory Bulb and the Effect of Adiponectin Injection on Insulin Receptor Expression
Published 2017-01-01“…We performed the double immunofluorescence technique to describe the distribution of AdipoRs and the cellular type they were expressing. mRNA transcript and protein content were assessed by RT-PCR and Western blot, respectively. …”
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751
雌激素对乳鼠心肌细胞脑钠肽表达的影响及机制
Published 2014-01-01“…【结果】 雌激素刺激能够显著上调心肌细胞内的BNP mRNA以及蛋白水平(P< 0.05),雌激素受体抑制剂ICI 182 780能够抑制该效应(P < 0.05)。…”
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752
Generation of IgM+ B cell-deficient Atlantic salmon (Salmo salar) by CRISPR/Cas9-mediated IgM knockout
Published 2025-01-01“…Notably, an upregulation of IgT mRNA was observed, suggesting a potential compensatory mechanism. …”
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753
Polymorphism of the rps16 gene intron in Malus Mill. and related Rosaceae Juss. species
Published 2017-11-01“…Domains V and VI were the most conservative, which may be due to their role in the positioning of the pre-mRNA structures and formation of the catalytically active secondary structure. …”
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754
Suppression of Matrix Metalloproteinase Production in Nasal Fibroblasts by Tranilast, an Antiallergic Agent, In Vitro
Published 2005-01-01“…The influence of TR on mRNA expression of MMPs and TIMPs in cells cultured for 12 hours was also evaluated by RT-PCR. …”
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755
Overexpression of microRNA-211 in Functional Dyspepsia via Downregulation of the Glial Cell Line-Derived Neurotrophic Factor (GDNF) by Increasing Phosphorylation of p38 MAPK Pathwa...
Published 2022-01-01“…Transfection with miR-211 mimics significantly decreased GDNF mRNA expression and protein secretion (p<0.001). …”
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756
Swimming Exercise Alleviated Insulin Resistance by Regulating Tripartite Motif Family Protein 72 Expression and AKT Signal Pathway in Sprague-Dawley Rats Fed with High-Fat Diet
Published 2016-01-01“…After 8 weeks, glucose infusion rate (GIR), markers of oxidative stress, mRNA and protein expression of TRIM72, protein of IRS, p-AKTSer473, and AKT were determined in quadriceps muscles. …”
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757
晚期糖基化终产物通过肾素-血管紧张素系统上调内皮细胞血管生成样蛋白-4的表达
Published 2013-01-01“…【方法】 不同浓度晚期糖基化终产物(AGE)干预内皮细胞24 h,实时荧光定量PCR 和免疫印迹检测血管生成样蛋白-4 mRNA和蛋白的表达,酶联免疫吸附试验法(ELISA)检测细胞上清和裂解液中血管紧张素Ⅱ的浓度,异硫氰酸荧光素标记的葡聚糖漏出率和跨内皮电阻检测内皮细胞的通透性?…”
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758
ppENK Gene Methylation Status in the Development of Pancreatic Carcinoma
Published 2013-01-01“…Methylated ppENK was detected in all the pancreatic cancer cell lines and was associated with loss of mRNA expression in the pancreatic carcinoma cell lines and normal pancreatic tissue. …”
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759
Construction of AMPK-related circRNA network in mouse myocardial ischemia–reperfusion injury model
Published 2024-12-01“…Results MIRI model was successfully constructed, and two AMPK related differentially expressed loops (novel_circ_043550 and novel_circ_035243) were screened out. A circRNA-miRNA-mRNA network consisting of 2 circRNA, 28 microRNA(miRNA) and 229 messengerRNA (mRNA) was constructed. …”
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760
Wharton’s Jelly-Derived Mesenchymal Stem Cells with High Aurora Kinase A Expression Show Improved Proliferation, Migration, and Therapeutic Potential
Published 2022-01-01“…This study is aimed at identifying the upregulated genes in human Wharton’s jelly-derived MSCs (WJ-MSCs) with high proliferation potential using mRNA sequencing. Aurora kinase A (AURKA) and dedicator of cytokinesis 2 (DOCK2) were selected as the upregulated genes, and their effects on proliferation, migration, and colony formation of the WJ-MSCs were verified using small interfering RNA (siRNA) techniques. mRNA expression levels of both the genes were positively correlated with the proliferation capacity of WJ-MSCs. …”
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