Regulatory Role of rno-miR-30b-5p in IL-10 and Toll-like Receptor 4 Expressions of T Lymphocytes in Experimental Autoimmune Uveitis In Vitro by Yuanyuan Sun, Dadong Guo, Bin Liu, Xuewei Yin, Huixia Wei, Kai Tang, Hongsheng Bi

“…MicroRNAs (miRNAs) are a class of small noncoding RNAs which regulate messenger RNA (mRNA) expression. It is predicted that rno-miR-30b-5p can regulate the expressions of interleukin-10 (IL-10) and Toll-like receptor 4 (TLR4). …”
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CircSLC8A1_005通过编码蛋白抑制心肌成纤维细胞纤维化表型的作用 by 胡雅婷, 高原, 伍华燕, 梁俣, 李晖, 徐金东, 刘宇鹏, 单志新

“…通过RNA结合蛋白免疫沉淀（RIP）实验检测SLC8A1-605aa与Sod2 mRNA的结合作用。放线菌素D实验检测SLC8A1-605aa对Sod2 mRNA稳定性的影响。结果利用腺病毒可在mCFs中有效介导过表达circSLC8A1_005，过表达circSLC8A1_005可显著抑制mCFs中纤维化相关基因表达，抑制mCFs的增殖和迁移能力。…”
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The Response of Corneal Endothelial Cells to Shear Stress in an In Vitro Flow Model by Sujuan Duan, Yingjie Li, Yanyan Zhang, Xuan Zhu, Yan Mei, Dongmei Xu, Guofu Huang

“…The expression of the corneal endothelium-related markers ZO-1, N-cadherin, and Na+-K+-ATPase in rabbit corneal endothelial cells (RCECs) was upregulated at both the mRNA and protein levels after exposure to shear stress. …”
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人巨细胞病毒对红系祖细胞的影响 by 陈健良, 何政贤, 李建英, 李　琨, 王清文, 邹小兵, 黄略峰

“…CFU-E 集落细胞中的HCM V DNA 均为阳性, 而late m RNA 为阴性。【结论】HCMV AD169 株可直接感染红系祖细胞, 并抑制其分化与增殖, 该抑制作用可出现于仅有病毒潜伏的细胞。…”
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Tissue Factor Expression in Obese Type 2 Diabetic Subjects and Its Regulation by Antidiabetic Agents by Jing Wang, Theodore P. Ciaraldi, Fahumiya Samad

“…Plasma TF antigen, activity, and adipose TF mRNA were greater in obese T2D subjects compared with obese nondiabetics. …”
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Chronic asymptomatic orchitis in dogs alters Sertoli cell number and maturation status by Pauline Rehder, Eva-Maria Packeiser, Hanna Körber, Sandra Goericke-Pesch

“…Sertoli cells also partly returned to an immature status, as indicated by the expression of AMH and CK18 at mRNA and protein levels. The degree of spermatogenesis disruption matched with the degree of Sertoli cell alterations. …”
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tRNA-Uridine Aminocarboxypropyltransferase DTW Domain Containing 2 Suppresses Colon Adenocarcinoma Progression by Yun Qian, Yu-Jiang Li, Yi-Wei Fu, Cui-Xia Liu, Juan Wang, Bin Yang

“…Besides, we tested its mRNA and protein expression in our enrolled retrospective cohort. …”
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Articular Cartilage Gene Expression after Coxofemoral Joint Luxation in the Dog by Korakot Nganvongpanit, Waranee Pradit, Siriwadee Chomdej

“…Ten mRNA, including nonapoptotic genes (AGG, COL2A1, MMP-3, HAS-1, HAS-2, and TIMP-1) and apoptotic genes (BAX, BCL-2, CAS-3, and CAS-9), were studied for their expression using real-time PCR. …”
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Mutanome Engineered RNA Immunotherapy: Towards Patient-Centered Tumor Vaccination by Mathias Vormehr, Barbara Schrörs, Sebastian Boegel, Martin Löwer, Özlem Türeci, Ugur Sahin

“…Preclinical and early clinical data suggest that synthetic mRNA can serve as potent drug format allowing the cost efficient production of highly efficient vaccines in a timely manner. …”
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Altered Peroxisome-Proliferator Activated Receptors Expression in Human Endometrial Cancer by Paweł Knapp, Adrian Chabowski, Agnieszka Błachnio-Zabielska, Katarzyna Jarząbek, Sławomir Wołczyński

“…We sought to analyze PPARs mRNA content as well as protein immunohistochemical expression that was further quantified by Western Blot technique. …”
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Goblet Cells and Mucin Related Gene Expression in Mice Infected with Eimeria papillata by Mohamed A. Dkhil, Denis Delic, Saleh Al-Quraishy

“…Moreover, the mRNA expression of TLR4 was significantly upregulated, whereas the expression of MUC2 is significantly downregulated upon infection. …”
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Suppression of Human Tenon Fibroblast Cell Proliferation by Lentivirus-Mediated VEGF Small Hairpin RNA by Zhongqiu Li, Wen Hua, Xuedong Li, Wei Wang

“…Lentivirus-VEGF-shRNA was constructed and transfected into HTF cells. Subsequently, VEGF mRNA and protein expression were analyzed using quantitative RT-PCR and western blotting, respectively, and the effects of VEGF knockdown were analyzed. …”
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Nationwide multi-centric prospective study for the identification of biomarkers to predict the treatment responses of nivolumab through comprehensive analyses of pretreatment plasm... by Kuniaki Sato, Satoshi Toh, Taku Murakami, Takafumi Nakano, Takahiro Hongo, Mioko Matsuo, Kazuki Hashimoto, Masashi Sugasawa, Keisuke Yamazaki, Yushi Ueki, Torahiko Nakashima, Hideoki Uryu, Takeharu Ono, Hirohito Umeno, Tsutomu Ueda, Satoshi Kano, Kiyoaki Tsukahara, Akihito Watanabe, Ichiro Ota, Nobuya Monden, Shigemichi Iwae, Takashi Maruo, Yukinori Asada, Nobuhiro Hanai, Daisuke Sano, Hiroyuki Ozawa, Takahiro Asakage, Takahito Fukusumi, Muneyuki Masuda

“…This nationwide multi-centric prospective study aimed to identify a plasma exosome (PEX) mRNA signature, which serves as a companion diagnostic of nivolumab and provides a biological clue to develop effective therapies for a majority of non-survivors.MethodsPre-treatment plasmas (N = 104) of RM-HNSCC patients were subjected to comprehensive PEX mRNA analyses for prognostic marker discovery and validation. …”
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Antibody Avidity and Neutralizing Response against SARS-CoV-2 Omicron Variant after Infection or Vaccination by Francesca Dapporto, Serena Marchi, Margherita Leonardi, Pietro Piu, Piero Lovreglio, Nicola Decaro, Nicola Buonvino, Angela Stufano, Eleonora Lorusso, Emilio Bombardieri, Antonella Ruello, Simonetta Viviani, Eleonora Molesti, Claudia Maria Trombetta, Alessandro Manenti, Emanuele Montomoli

“…Samples were collected from 42 SARS-CoV-2 infected patients during the first pandemic wave, 50 subjects who received 2 doses of mRNA vaccine before the Omicron wave, 44 subjects who received 3 doses of mRNA vaccine, and 35 subjects who received heterologous vaccination (2 doses of adenovirus-based vaccine plus mRNA vaccine) during the Omicron wave. …”
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Effects of early neonatal proinflammatory stress on the expression of BDNF transcripts in the brain regions of prepubertal male rats by D. I. Peregud, S. V. Freiman, A. O. Tishkina, L. S. Sokhranyaeva, N. A. Lazareva, M. V. Onufriev, M. Y. Stepanichev, N. V. Gulyaeva

“…In the rats treated with LPS, the level of BDNF mRNA, containing exon IV, was lower in the neocortex, but not in the hippocampus. …”
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Liraglutide Enhances the Activity of the ACE-2/Ang(1–7)/Mas Receptor Pathway in Lungs of Male Pups from Food-Restricted Mothers and Prevents the Reduction of SP-A by J. Fandiño, A. A. Vaz, L. Toba, M. Romaní-Pérez, L. González-Matías, F. Mallo, Y. Diz-Chaves

“…Surfactant protein B (SP-B) mRNA expression is not affected by neither IUGR nor liraglutide treatment. …”
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The in vitro anticancer effects of FS48 from salivary glands of Xenopsylla cheopis on NCI-H460 cells via its blockage of voltage-gated K+ channels by Xiong Weichen, Fan Huizhen, Zeng Qingye, Deng Zhenhui, Li Guanhui, Lu Wancheng, Zhang Bei, Lai Shian, Chen Xin, Xu Xueqing

“…Finally, FS48 decreases the mRNA level of MMP-9 while increasing TIMP-1 mRNA level. …”
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糖尿病合并脓毒症小鼠肠损伤特点 by 庞昌季, 谭芳, 郑磊, 曹钰玲, 邓颖青, 池信锦

“…结果CLP后12 h，DMCLP组小鼠肠组织病理损伤Chiu's评分显著升高，肠组织Occludin、ZO-1蛋白表达量降低（<italic>P</italic>＜0.05）；DMCLP组小鼠肠组织巨噬细胞数量明显增加，M1标志物iNOS、CRR7 mRNA表达显著升高，炎症因子TNF-α、IL-1β和IL-6 mRNA表达明显上升（<italic>P</italic>＜0.05）。…”
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IL-10在系统性红斑狼疮患者PBMC B细胞刺激因子表达中的作用 by 叶玉津, 梁柳琴, 许韩师, 杨岫岩, 詹钟平, 连帆, 尹培达

“…【方法】梯度密度离心法分离25例系统性红斑狼疮患者和20名女性健康志愿者外周血单个核细胞,分为2组,IL-10(100ng/mL)组和培养基组(仅含RPMI1640培养基),分别于培养0、6、12、24、72h离心收集PBMCs,RT-PCR法检测刺激后0～24h细胞Blys mRNA表达,流式细胞仪和直接免疫荧光法检测72h膜结合型Blys蛋白表达。【结果】①系统性红斑狼疮患者外周血单个核细胞Blys mRNA和蛋白表达体外高于健康对照(P<0.001)。…”
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Wnt/ β-catenin and CTNNB1 gene mutation in hepatocellular carcinoma, a case study in Egyptian patients by Ramy A. Abdelsalam, Ibrahim M. El-Shawaf, Azza Abdel-Aziz, Tarek A. Bismar, Shaimaa M. Yussif

“…The relation between aberrant β-Catenin, Wnt2 IHC staining and CTNNB1 mRNA expression and different clinicopathological characteristics was studied. …”
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