Showing 561 - 580 results of 2,553 for search '"mRNA"', query time: 0.08s Refine Results
  1. 561

    QRFP43 modulates the activity of the hypothalamic-pituitary-thyroid axis in female sheep by Bartosz Jarosław Przybył, Michał Szlis, Anna Misztal, Anna Wójcik-Gładysz

    Published 2025-01-01
    “…Moreover, the relationship between QRFP34 and mRNA expression of the Dio1, Dio2, and Dio3 genes was explored in selected tissues of the HPT axis. …”
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  2. 562

    RETRACTED ARTICLE: Combined treatment of glibenclamide and CoCl2 decreases MMP9 expression and inhibits growth in highly metastatic breast cancer by Zhe Rong, Li Li, Fei Fei, Lailong Luo, Yang Qu

    Published 2013-05-01
    “…Some fresh tissues without necrosis were stored at −80°C for mRNA detection and the other tumor tissue was fixed with 10% formalin for H&E and immunohistochemical staining. …”
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  3. 563

    大鼠脑缺血/再灌注过程中脑型葡萄糖转运体在缺血半影区的表达 by 李方成, 陶宗玉, 刘安民, 李军亮, 吴中华, 林吉惠

    Published 2005-01-01
    “…MCAO1h/R 组GLUT1、GLUT3 mRNA 缺血后升高, 24 h 到达高峰, 但GLUT1 比GLUT3 提前升高, 且升高的幅度更大。 …”
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  4. 564

    Inhibitory Effect of Lactobacillus delbrueckii subsp. bulgaricus KSFY07 on Kappa-Carrageenan-Induced Thrombosis in Mice and the Regulation of Oxidative Damage by Pan Wang, Fang Tan, Jianfei Mu, Hongjiang Chen, Xin Zhao, Yanan Xu

    Published 2022-01-01
    “…Further, experimental results showed that LDSB-KSFY07 was able to upregulate the mRNA expression of copper/zinc-SOD (Cu/Zn-SOD), manganese-SOD, and GSH-Px in the liver tissue of thrombotic mice. …”
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  5. 565

    Transcriptional Regulation of Δ6-Desaturase by Peroxisome Proliferative-Activated Receptor δ Agonist in Human Pancreatic Cancer Cells: Role of MEK/ERK1/2 Pathway by Maryam Darabi, Shima Byagowi, Shabnam Fayezi, Masoud Darabi, Shahab Mirshahvaladi, Mehdi Sahmani

    Published 2013-01-01
    “…Furthermore, there may be an inhibitory crosstalk between these two regulatory pathways on the mRNA expression of Δ6D and subsequently on Δ6D protein expression.…”
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  6. 566

    马鹿<italic>CDK8</italic>基因生物信息学分析与组织表达 by 唐成怡, 吴玄烨, 吴尽, 杨帆, 刘学东

    Published 2023-08-01
    “…为探究细胞周期蛋白依赖性蛋白激酶8基因(<italic>CDK8</italic>)在马鹿(<italic>Cervus elaphus</italic>)鹿茸的皮、间充质、前软骨和软骨组织中的mRNA表达水平和该基因编码蛋白的生物学特性,采用PCR方法克隆马鹿<italic>CDK8</italic>基因编码区(CDS)全长序列,并连入pMD-18T载体,测得核苷酸序列,进行相似性比对和系统进化树构建;利用生物信息学方法分析CDK8蛋白的组成、结构和理化性质;利用实时荧光定量PCR技术检测<italic>CDK8</italic>基因mRNA在鹿茸组织中的表达水平。…”
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  7. 567

    P-glycoprotein and/or Histone Deacetylase 2 Regulates Steroid Responsiveness in Childhood Nephrotic Syndrome by Harshit Singh, Narayan Prasad, Durga Prasanna Misra, Akhilesh Kumar Jaiswal, Vikas Agarwal

    Published 2020-01-01
    “…Similarly, the expression of HDAC2 mRNA was significantly higher at baseline and at remission following 6-week steroid therapy as compared to their expression in those who were resistant to steroids (P < 0.005). …”
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  8. 568

    Exploring the prognostic role of microbial and genetic markers in lung squamous cell carcinoma by Fan Yang, Xiaodong Jia, Zihuan Ma, Siyao Liu, Chunzi Liu, Dan Chen, Xiuju Wang, Niansong Qian, Hui Ma

    Published 2025-02-01
    “…The microbial signature built with these microbial genera, exhibited robust predictive accuracy in both the training and validation datasets. Furthermore, hub mRNA between high- and low-risk groups were selected by XGBOOST and intersect with mRNAs screened by univariate Cox regression analysis, finally identifying four mRNA significantly associated with LUSC prognosis. …”
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    Article
  9. 569

    Influence of Dietary Chromium and Vitamin E Supplementation on Performance, Metabolism, and Physiology of Broilers Subjected to Cyclic Heat Stress by ML X Júnior, RD Bernardes, CH Oliveira, KMM Dias, BF Almeida, SO Borges, FS Dalólio, KM Gomes, CJ Rodrigues, AA Calderano

    Published 2025-01-01
    “…ABSTRACT This experiment evaluated the influence of chromium (Cr) and vitamin E (VitE) supplementation on the performance, glucose levels, thyroid hormone levels, immune and oxidative response, and 70 kilodalton heat shock protein (HSP70) mRNA expression of broilers under heat stress (HS). …”
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  10. 570

    Effects of Placenta-Derived Mesenchymal Stem Cells on the Particulate Matter-Induced Damages in Human Middle Ear Epithelial Cells by So Young Kim, Seung Ha Oh, Jun Ho Lee, Myung-Whan Suh, Moo Kyun Park

    Published 2019-01-01
    “…The mRNA expression levels of PGE2, TGFβ, and VEGF were elevated in cocultured PL-MSCs compared to those of control PL-MSCs. …”
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  11. 571

    Effects of Maternal Hypoxia during Pregnancy on Bone Development in Offspring: A Guinea Pig Model by Alice M. C. Lee, Janna L. Morrison, Kimberley J. Botting, Tetyana Shandala, Cory J. Xian

    Published 2014-01-01
    “…MH did not change primary spongiosa height but lowered collagen-1 mRNA expression in postnatal offspring. There was increased mRNA expression of adipogenesis-related gene (FABP4) in bone from the MH postnatal offspring. …”
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  12. 572

    Role of Transforming Growth Factor-β1 and Smads Signaling Pathway in Intrauterine Adhesion by Umme Salma, Min Xue, Md Sayed Ali Sheikh, Xiaoming Guan, Bin Xu, Aiqian Zhang, Lihua Huang, Dabao Xu

    Published 2016-01-01
    “…This altered ratio recommended that IUA was positively correlated to the mRNA and protein expression levels of Smad3, Smad7, and TGF-β1 in blood and uterine tissue. …”
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    Article
  13. 573

    YBX1 alleviates ferroptosis in osteoporosis via the ATF4/FSP1 axis in an m5C manner by Lei Tong, Yanbo Chen, Yan Gao, Xiaoming Gao, Yanming Hao

    Published 2025-01-01
    “…RNA pulldown and RNA immunoprecipitation experiments were used to determine the binding between YBX1 and ATF4 mRNA and to test the effect of YBX1 on ATF4 mRNA stability in a 5-methylcytosine (m5C)-dependent manner. …”
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  14. 574

    eIF3 engages with 3’-UTR termini of highly translated mRNAs by Santi Mestre-Fos, Lucas Ferguson, Marena I Trinidad, Nicholas T Ingolia, Jamie HD Cate

    Published 2025-01-01
    “…The results presented here show that eIF3 engages with 3’-UTR termini of highly translated mRNAs, likely reflecting a general rather than specific regulatory function of eIF3, and supporting a role of mRNA circularization in the mechanisms governing mRNA translation.…”
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  15. 575

    METTL3 inhibition promotes radiosensitivity in hepatocellular carcinoma through regulation of SLC7A11 expression by Chen Zhang, Tianpeng Yang, Hanbin Chen, Xiaofeng Ding, Huajian Chen, Zhenzhen Liang, Yinlong Zhao, Shumei Ma, Xiaodong Liu

    Published 2025-01-01
    “…Mechanistically, METTL3 targeted adenine (+1795) on the SLC7A11 mRNA, and the m6A reader IGF2BP2 promoted SLC7A11 mRNA stability by recognizing and binding to the m6A site. …”
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  16. 576

    Indoleamine 2,3-Dioxygenase (IDO) Expression Is an Independent Prognostic Marker in Esophageal Adenocarcinoma by Heike Loeser, Max Kraemer, Florian Gebauer, Christiane Bruns, Wolfgang Schröder, Thomas Zander, Hakan Alakus, Arnulf Hoelscher, Reinhard Buettner, Philipp Lohneis, Alexander Quaas

    Published 2020-01-01
    “…We analyzed 551 patients with EAC using single-protein and multiplex immunohistochemistry as well as mRNA in situ technology for the expression and distribution of IDO on subtypes of TILs (INF-γ mRNA and CD4- and CD8-positive T lymphocytes). …”
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  17. 577

    Nutrient Induced Type 2 and Chemical Induced Type 1 Experimental Diabetes Differently Modulate Gastric GLP-1 Receptor Expression by Olga Bloch, Efrat Broide, Gilad Ben-Yehudah, Dror Cantrell, Haim Shirin, Micha J. Rapoport

    Published 2015-01-01
    “…In contrast, SD diabetic rats demonstrated decreased GLP-1 mRNA, cellular GLP-1R immunoreactivity, and frequency of GLP-1R immunoreactive cells in the neck area compared with controls. …”
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    Article
  18. 578

    High Intestinal and Systemic Levels of Interleukin-23/T-Helper 17 Pathway in Chinese Patients with Inflammatory Bowel Disease by Lu Song, Rui Zhou, Sha Huang, Feng Zhou, Shufang Xu, Wei Wang, Fengming Yi, Xiaobing Wang, Bing Xia

    Published 2013-01-01
    “…Our results indicated that the mRNA levels of IL-12p40 and TL1A were increased in ulcerative colitis (UC) patients. …”
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  19. 579

    SPARC Levels Modulate the Capacity of Mitomycin to Inhibit the Proliferation of Human Tenon’s Capsule Fibroblasts by Yuanyuan Guo, Shouxiang Ni, Weiyan Zhou, Jiangping Hou, Jiaquan Shen

    Published 2020-01-01
    “…Compared to control, the si-SPARC and MMC downregulated the SPARC protein by 91% (P<0.01) and 65% (P<0.01) and mRNA by 96% (P<0.01) and 64% (P<0.01), respectively. …”
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  20. 580

    The Effect and Mechanism of TLR9/KLF4 in FFA-Induced Adipocyte Inflammation by Cuizhe Wang, Meixiu Zhang, Jinxiu Wu, Wei Li, Xiaodan Ha, Yajuan Gu, Bo Han, Jianxin Xie, Jun Zhang

    Published 2018-01-01
    “…Methods. qRT-PCR and Western blot were used to detect the mRNA and protein expression levels of TLR9, KLF4, and key inflammation-related factors. …”
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    Article