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  1. 421

    Impact of COVID-19 vaccination on tinnitus onset and severity: a comprehensive survey study by Anusha Yellamsetty, Egbe-Etu Etu, Shaowen Bao

    Published 2025-02-01
    “…There was no significant difference in tinnitus onset latency between mRNA vaccines (Pfizer and Moderna) and non-mRNA vaccines (Johnson & Johnson). …”
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  2. 422
  3. 423

    Effects of Dendrobium Officinale Polysaccharides on Brain Inflammation of Epileptic Rats by Lin Zhang, Hua Peng, Jin Xu, Yixin Xu, You Yin, Bin He, Jianhua Zhuang

    Published 2019-01-01
    “…At weeks 1, 2, 3, and 4 after modeling, there were no significant differences between the control group and the DOPS group in the mRNA and protein expression of IL-1β and TNF-α and phosphorylation of ERK1/2, JNK, p38, and MKP-1 (all P>0.05); the mRNA and protein expression of IL-1β and TNF-α and phosphorylation of ERK1/2, JNK, and p38 were significantly increased, while the phosphorylation of MKP-1 was decreased in the model group compared with the control group. …”
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  4. 424

    Effects of Stroke-ⅡOral Liquid on TLR4/MyD88/NF-κB Signal Pathway in Chemical Damaged PC12 Cells by Xinfu LIN, Ling SHI, Hengzhao ZHU, Sujuan CHEN, Xuehua ZHENG, Yiman WU

    Published 2016-12-01
    “…The cell proliferation was observed by MTT assay, the expression of TLR4, MyD88 and NF-κB mRNA were detected by RT-PCR, and their protein expressions were detected by Western Blot.Results:Compared with the blank control group, the proliferation of PC12 cells in the model group was decreased (<italic>P</italic>&lt;0.01), and the expression of TLR4, MyD88 and NF-κB mRNA and protein were increased significantly (<italic>P</italic>&lt;0.01, <italic>P</italic>&lt;0.05). …”
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  5. 425

    Troglitazone and Δ2Troglitazone Enhance Adiponectin Expression in Monocytes/Macrophages through the AMP-Activated Protein Kinase Pathway by Jaw-Shiun Tsai, Lee-Ming Chuang, Ching-Shih Chen, Chan-Jung Liang, Yuh-Lien Chen, Ching-Yu Chen

    Published 2014-01-01
    “…TG induced adiponectin mRNA expression through a PPARγ-dependent pathway whereas Δ2TG enhanced adiponectin mRNA expression through a PPARγ-independent pathway in THP-1 cells. …”
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  6. 426

    Regulation of interferon alpha production by the MAGUK-family protein CASK under H5N1 infection by Jing-Ying Huang, Jing-Ying Huang, Pei-Shan Sung, Shie-Liang Hsieh, Shie-Liang Hsieh, Shie-Liang Hsieh, Shie-Liang Hsieh

    Published 2025-01-01
    “…These associations recruit IRF7, POLR2C, TAF15, HNRNPs, and CRM1, enabling the CASK complex to bind to the Ifna promoter, bind co-transcriptionally to Ifna mRNA, and facilitate CRM1-dependent Ifna mRNA export. …”
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  7. 427

    Expression and significance of CEMIP and CYP11B2 in serum in women with foetal growth restriction by Yang Yue, Fang Fang Zhou, Jia Rong Zhang, Fu Xu

    Published 2024-12-01
    “…The diagnostic value of CEMIP and CYP11B2 for FGR was analysed.Results CEMIP and CYP11B2 mRNA expression in the serum of pregnant women with FGR decreased (both P < 0.001). …”
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  8. 428

    A prevalent caveolin-1 gene rs926198 variant is associated with type 2 diabetes mellitus in the Thai population by Metha Yaikwawong, Pornpimon Ek-eudomsuk, Gunya Sittithumcharee, Vipavee Anupunpisit, Thavatchai Peerapatdit, Chaicharn Deerochanawong, Thep Himathongkam, Siwanon Jirawatnotai, Somlak Chuengsamarn

    Published 2024-11-01
    “…Additionally, patients with Mets and T2DM who had the rs926198 variant exhibited a significant 44.3% reduction in CAV1 mRNA expression (P < 0.05). Clinical samples revealed that the rs926198 variant is strongly linked to T2DM, with significantly reduced CAV1 mRNA. …”
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  9. 429

    Opposing Effects of Omega-3 and Omega-6 Long Chain Polyunsaturated Fatty Acids on the Expression of Lipogenic Genes in Omental and Retroperitoneal Adipose Depots in the Rat by B. S. Muhlhausler, R. Cook-Johnson, M. James, D. Miljkovic, E. Duthoit, R. Gibson

    Published 2010-01-01
    “…The relationship between total n-6 PUFA and SREBP1c mRNA expression persisted when the effects of n-3 PUFA were controlled for. …”
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  10. 430

    Acanthopanax versus 3-Methyladenine Ameliorates Sodium Taurocholate-Induced Severe Acute Pancreatitis by Inhibiting the Autophagic Pathway in Rats by Xiaohong Wang, Guoxiong Zhou, Chun Liu, Ronglong Wei, Shunxing Zhu, Yuefen Xu, Mengjie Wu, Qing Miao

    Published 2016-01-01
    “…Serum amylase levels, protein, and mRNA expression levels of nucleus NF-κB p65, LC3-II, and Beclin-1 protein, mRNA expression levels of PI3K-III, and pathological score of the pancreas in both treatment groups were significantly lower than those in SAP group at 12 and 24 h after operation (P<0.05 or 0.01). …”
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  11. 431

    Prostacyclin Synthase: Upregulation during Renal Development and in Glomerular Disease as well as Its Constitutive Expression in Cultured Human Mesangial Cells by Thomas Klein, Günther Klaus, Martin Kömhoff

    Published 2015-01-01
    “…Under these conditions expression of PGIS mRNA and protein remained unaltered whereas mRNA for cyclooxygenase-2 was markedly induced. …”
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  12. 432

    Multiple Regression Analysis Reveals MicroRNA Regulatory Networks in Oryza sativa under Drought Stress by Jiajia Chen, Liangzhi Li

    Published 2018-01-01
    “…Here we performed microarray analysis of miRNAs and matched mRNA expression profiles of drought-treated rice cultivar Nipponbare. …”
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  13. 433

    Spatio-temporal models of synthetic genetic oscillators by Cicely K. Macnamara, Mark A. J. Chaplain

    Published 2017-01-01
    “…If the binding reduces the transcription rate there is a negative feedback leading to oscillatory behaviour in mRNA and protein levels, both spatially (e.g. by observing fluorescently labelled molecules in single cells) and temporally (e.g. by observing protein/mRNA levels over time). …”
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  14. 434

    The Expression of miR-34a in Gingival Crevicular Fluid of Chronic Periodontitis and Its Connection with the TLR/NF-κB Signaling Pathway by Jiaxin Pan, Jue Liu, Lu Zhao

    Published 2022-01-01
    “…We collected the GCF of the two groups of subjects, using RT-PCR to detect the expression of miR-34a and NF-κB p65 mRNA and TLR4 mRNA and ELISA to detect the inflammatory factor degree in GCF, and performed periodontal examinations on both groups. …”
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  15. 435

    以地高辛标记探针检测瘦素基因的表达 by 徐明彤, 钟光恕, 傅祖值

    Published 2001-01-01
    “…【结论】肥胖者脂肪组织瘦素mRNA 水平明显增高, 且与BM I 呈正相关。…”
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  16. 436

    How energy determines spatial localisation and copy number of molecules in neurons by Cornelius Bergmann, Kanaan Mousaei, Silvio O. Rizzoli, Tatjana Tchumatchenko

    Published 2025-02-01
    “…We found that energy minimisation principles explain experimentally-reported exponential rank distributions of mRNA and protein copy numbers. Our results further reveal robust energy benefits when certain mRNA classes are moved into dendrites, for example mRNAs of proteins with long amino acid chains or mRNAs with large non-coding regions and long half-lives proving surprising insights at the level of molecular populations.…”
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  17. 437

    Ovarian Development and Vitellogenin Gene Expression under Heat Stress in Silkworm, Bombyx mori by Satinath Paul, Bela Keshan

    Published 2016-01-01
    “…The study further showed a developmental- and tissue-specific expression of vitellogenin mRNA in fat body and ovary upon heat shock. When heat shock treatment was done at 39°C and 42°C to spinning larvae, ovary showed an upregulation in the expression of vitellogenin mRNA, whereas fat body failed to do so. …”
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  18. 438

    <i>Cannabis sativa</i> L. Extract Increases COX-1, COX-2 and TNF-α in the Hippocampus of Rats with Neuropathic Pain by Joanna Bartkowiak-Wieczorek, Małgorzata Jamka, Radosław Kujawski, Marcin Hołysz, Agnieszka Bienert, Kamila Czora-Poczwardowska, Michał Szulc, Przemysław Mikołajczak, Anna Bogacz, Anna-Maria Wizner, Karolina Wielgus, Ryszard Słomski, Edyta Mądry

    Published 2025-01-01
    “…Extract D dose-dependently increased COX-1 mRNA and protein in the hippocampus and cortex. In contrast, Extract B dose-dependently increased COX-1 mRNA and decreased COX-2 mRNA (in a dose of 7.5 mg/kg) and TNF-α protein levels in the cortex. …”
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  19. 439

    Circulating levels of adiponectin and AdipoR expression in peripheral blood mononuclear cells are associated with lower respiratory tract Infection by Qian Wang, Xuemei Wang, Danning Xu, Mengjie Jiang, Yidan Gao, Lijuan Jiang, Meilian Liu, Haoneng Tang, Lingli Tang

    Published 2025-01-01
    “…Serum APN was quantified using ELISA, and mRNA levels of PBMC AdipoRs were determined by RT-qPCR.ResultsBoth levels of APN in circulation and AdipoR1 mRNA were significantly elevated in the LRTI patients (P=2.61E-04; P=2.49E-08), while no statistical difference was observed for AdipoR2. …”
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  20. 440