冷冻保存时长对卵裂期胚胎组蛋白表观遗传修饰的影响 by 马家璇

“…同时去乙酰化酶HDAC1、甲基化酶SUV39H1对应mRNA的表达量也无统计学意义的差异（P>0.05）。随着胚胎冷冻时长的增加，甲基化酶SETDB1对应mRNA的表达量有递增趋势，然而差异无统计学意义（P>0.05）。…”
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THE CHARACTERISTICS OF MIRNA BINDING SITES IN MRNA OF ZFHX3 GENE AND ITS ORTHOLOGS by A. М. Kondybayeva, A. N. Akimniyazova, S. U. Kamenova, A. Т. Ivashchenko

“…The characteristics of miRNA–mRNA interaction were determined using MirTarget software. …”
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Mild heat stress promotes the differentiation of odontoblast-like MDPC-23 cells via yes-associated protein by Peiqi Liu, Zhen Li, Hui Zhang, Yijie Wang, Yuxin Liao, Yi Guo, Chenxu Wang, Yuanwu Zou, Rui Zou, Lin Niu

“…MHS also increased YAP activity, as well as the levels of HSP25 mRNA, HSP70 mRNA, HSP90α mRNA, DMP1 mRNA, and DSPP protein. …”
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Purpurogallin, a Natural Phenol, Attenuates High-Mobility Group Box 1 in Subarachnoid Hemorrhage Induced Vasospasm in a Rat Model by Chih-Zen Chang, Chih-Lung Lin, Shu-Chuan Wu, Aij-Lie Kwan

“…Likewise, high dose purpurogallin reduced TNF-α and HMGB1 mRNA levels. In conclusion, purpurogallin exerts its neuroinflammation effect through the dual effect of inhibiting IL-6 and TNF-α mRNA expression and reducing HMGB1 protein and mRNA expression. …”
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IL-18在系统性红斑狼疮肾损害患者外周血中过度表达 by 米向斌, 谭国珍, 曾凡钦

“…【方法】采用RT-PCR及ELISA法测定了20例SLE患者(其中10例伴有肾损、10例无肾损)及10例健康人的外周血单个核细胞(PBMC)表达IL-18 mRNA和血清IL-18蛋白水平。【结果】SLE肾损组和非肾损组、健康对照组PBMC的IL-18 mRNA表达分别为1.35±0.30、0.91±0.27、0.69±0.17。…”
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Differential Expression of Motilin Receptor in Various Parts of Gastrointestinal Tract in Dogs by Yu He, Hui Wang, DongYan Yang, ChengYan Wang, LanLan Yang, Chunxiang Jin

“…The expression levels of motilin receptor mRNA in different regions were measured by RT-PCR. …”
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Importance of the 5’ untranslated region for recombinant enzyme production in isolated Bacillus subtilis 007 by Jana Senger, Adriana Schulz, Ines Seitl, Martin Heider, Lutz Fischer

“…Since the aprE 5’ untranslated region contributes to a high mRNA stability, it was incorporated into the P43 construct to determine whether mRNA stability is responsible for the differences observed in β-galactosidase production. …”
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Chimonanthus nitens Oliv. leaves flavonoids alleviate hyperuricemia by regulating uric acid metabolism and intestinal homeostasis in mice by Wenya Meng, Lingli Chen, Kehui Ouyang, Suyun Lin, Yang Zhang, Jing He, Wenjun Wang

“…In addition, CLF repaired renal injury by significantly down-regulating mRNA and protein expressions of renal UA reabsorption-related proteins and up-regulating the mRNA and protein expressions of UA secretory-related proteins. …”
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干扰素α、5-AZA-CdR对白血病细胞HL-60和K562的作用 by 黄云燕, 夏焱, 郭海霞, 李文益

“…[方法]1000U/mL INFα和不同剂量的5-AZA-CdR作用于HL-60和K562 48h,通过RT-PCR检测Xaf1和XIAP mRNA的表达,流式细胞技术检测Bcl-2家族成员、线粒体膜电位（Δψm）和细胞凋亡的情况。[结果]INFα和5-AZA-CdR使HL-60和K562 Xaf1 mRNA表达增加,且与5-AZA-CdR呈剂量依赖性,其中5-AZA-CdR（5μmol/L）的作用最明显;XIAP mRNA表达无变化。…”
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Effects of cardiac contractility modulation on autophagy and apoptosis of cardiac myocytes in rabbits with chronic heart failure. by Qingqing Hao, Shilin Lv, Jing Zhang, Huiliang Liu

“…However, the expression of ALDH2 mRNA in the CCM group was not statistically significant. …”
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JNK Signaling Pathway Suppresses LPS-Mediated Apoptosis of HK-2 Cells by Upregulating NGAL by Mei Han, Yuxia Pan, Mengying Gao, Junli Zhang, Fan Wang

“…NGAL and caspase-3 gene expression levels were then determined. Results. NGAL mRNA was increased significantly within 6 hours, and caspase-3 mRNA was increased within 3 hours after treatment (P<0.05). …”
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MDR1 siRNA对结肠癌细胞多药耐药性的影响

“…[目的]探讨MDR1 siRNA对结肠癌细胞多药耐药性的影响。[方法]设计合成两种针对MDR1 mRNA的siRNA双链分子（#4123 MDR1 siRNA和#4029 MDR1 siRNA）,并转染入COLO 320DM和HT-29结肠癌细胞,观察其对结肠癌细胞MDR1 mRNA和P-gp表达的影响。…”
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The Expression of T Cell FOXP3 and T-Bet Is Upregulated in Severe but Not Euthyroid Hashimoto’s Thyroiditis by Stana Tokić, Mario Štefanić, Ljubica Glavaš-Obrovac, Sonja Jaman, Eva Novosadová, Jana Petrkova, Zdenka Navratilova, Mirjana Suver Stević, Martin Petrek

“…By contrast, no differences in mRNA expression levels of ETS1, BLIMP1, and HIF1α were observed across the study groups. …”
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伊马替尼抑制脂多糖诱导的巨噬细胞炎症表型

“…和LPS组相比，Ima提前处理后，IL-1β、CCL2、iNOS和TNF-α的mRNA及蛋白水平显著下降（P<0.01，P<0.001）而IL-10的mRNA及蛋白水平显著升高（P<0.001），这种抑制作用具有剂量依赖性。…”
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血管紧张素Ⅱ对心肌细胞内皮型 一氧化氮合酶基因表达的影响 by 詹昌德, 潘敬运

“…【方法】用逆转录聚合酶链式反 应(RT -PCR)检测新生大鼠心肌细胞 eNOS mRNA(以 GAPDH 为内标)水平。【结果】在培养新生大鼠心肌细胞和非心肌细 胞中均能检测到 eNOS mRNA ,其中心肌细胞的表达高于非心肌细胞; 血管紧张素Ⅱ作用 6、12 和 24 h, 心肌细胞 eNOS mRNA 水平明显减少。…”
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Entangled evidence: epistemic injustice, and systemic neglect in the assessment of menstrual disorders following COVID-19 vaccines by Maurizia Mezza

“…In the context of the COVID-19 pandemic, pharmacovigilance activities detected and assessed symptoms, such as rare blood clotting disorders, myocarditis, and erythema multiforme, potentially linked to some adenovirus-based and mRNA-based vaccines. While some presumed side effects were swiftly assessed, others, such as menstrual disorders following mRNA vaccination, were subjected to prolonged debates. …”
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Effects of Thalidomide on the Expression of Adhesion Molecules in Rat Liver Cirrhosis

“…Close positive correlation was observed in the expression of the TNF-<mml:math> <mml:mi>&#x03B1;</mml:mi> </mml:math> mRNA and that of ICAM-1, VCAM-1, and E-selectin mRNA, respectively. …”
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Effects of Thalidomide on the Expression of Adhesion Molecules in Rat Liver Cirrhosis by Peng Lv, Shelley Chireyath Paul, Yanjv Xiao, Shiquan Liu, Hesheng Luo

“…Close positive correlation was observed in the expression of the TNF-α mRNA and that of ICAM-1, VCAM-1, and E-selectin mRNA, respectively. …”
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控制性卵巢刺激对多囊卵巢综合征患者和正常排卵妇女卵源性因子表达的差异

“…在ＰＣＯＳ患者的颗粒细胞中，ＧＤＦ９和ＢＭＰ１５ ｍＲＮＡ的表达水平在未刺激组分别为０．１１ （０．０６， ０．１６）和０．０００ ００５（０．０００ ００４ ８－０．０００ ００９），在卵巢刺激组分别为０．０５ （０．０３， ０．０９）和０．０２（０．００７－０．０３）， ＧＤＦ９ ｍＲＮＡ的表达在卵巢刺激组显著低于未刺激组，而ＢＭＰ１５ ｍＲＮＡ的表达在卵巢刺激组显著高于未刺激组，差异均有统计学意义（Ｐ ＜ ０．０５）。…”
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改良的 Trizol 法提取小鼠皮肤 RNA 技术 by 林震嘉, 张辉, 揭英桃, 熊媖, 唐源, 谈智, 刘先国, 周利君

“…②在不同小鼠皮肤样本处理组中，改良的2-Tri法和LNG-Tri法获得的RNA浓度更高，同时RNA降解、DNA污染更低，IL-1β mRNA表达更接近正常水平。更重要的是，在小鼠银屑病模型中，2-Tri法提取的RNA样本能真实反映出正常皮肤与银屑病变皮肤之间IL-1β mRNA的变化趋势。…”
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