The Role of Serum Cytokines in the Pathogenesis of Hepatic Osteodystrophy in Male Cirrhotic Patients by Ali Riza Soylu, Cengiz Tuglu, Ender Arikan, Tarkan Yetisyigit, Hakan Kunduracılar, Ibrahim Hakki Koker, Gulbin Unsal, Ahmet Huseyin Tezel, Hasan Umit, Sakir Berkarda

“…Matherial and Methods. 44 consecutive male cirrhotic patients (17 alcoholic, 20 hepatitis B, 7 hepatitis C), 15 age- and sex-matched chronic alcoholics without liver disease, and 17 age- and sex-matched healthy controls were included in the study during one year period. …”
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Vaccinating Adult Patients with Cirrhosis: Trends over a Decade in the United States by Abhijeet Waghray, Nisheet Waghray, Hicham Khallafi, K. V. Narayanan Menon

“…The progression of chronic liver disease to cirrhosis involves both innate and adaptive immune system dysfunction resulting in increased risk of infectious complications. …”
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Apelin Serum Level in Egyptian Patients with Chronic Hepatitis C by Hala O. El-Mesallamy, Nadia M. Hamdy, Hanan H. Rizk, Abdel-Rahman El-Zayadi

“…Highlighting the apelin system would present a new therapeutic target for liver disease. Apelin; endogenous ligand for the orphan receptor APJ, was recently suggested to be associated with fibrosis progression and cirrhosis in addition to insulin resistance (IR) and inflammation. …”
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NIR-II-excited off-on-off fluorescent nanoprobes for sensitive molecular imaging in vivo by Yufu Tang, Yuanyuan Li, Chunxu He, Zhen Wang, Wei Huang, Quli Fan, Bin Liu

“…Abstract Strong background interference signals from normal tissues have significantly compromised the sensitive fluorescence imaging of early disease tissues with exogenous probes in vivo, particularly for sensitive fluorescence imaging of early liver disease due to the liver’s significant uptake and accumulation of exogenous nanoprobes, coupled with high tissue autofluorescence and deep tissue depth. …”
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Spinal cord injury induces transient activation of hepatic stellate cells in rat liver by Inmaculada Fernandez-Canadas, Alejandro Badajoz, Jesús Jimenez-Gonzalez, Martin Wirenfeldt, Beatriz Paniagua-Torija, Clara Bravo-Jimenez, Mar Del Cerro, Angel Arevalo-Martin, Daniel Garcia-Ovejero

“…Abstract Spinal cord injury (SCI) causes abnormal liver function, the development of metabolic dysfunction-associated steatotic liver disease features and metabolic impairment in patients. …”
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Exploring the application of dietary antioxidant index for disease risk assessment: a comprehensive review by Hossein Pourmontaseri, Sina Bazmi, Matin Sepehrinia, Matin Sepehrinia, Ayda Mostafavi, Reza Arefnezhad, Reza Arefnezhad, Reza Homayounfar, Farhad Vahid

“…It is suggested that a high DAI score prevents obesity-related diseases, including diabetes mellitus, hyperuricemia, dyslipidemia, and metabolic (dysfunction)-associated steatotic liver disease (MASLD). Additionally, DAI is negatively associated with Helicobacter pylori and Human papillomavirus infection, thus reducing the risk of gastric and cervical cancer. …”
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Fungal Bezoar: A Rare Cause of Ureteral Obstruction by Nabil Zeineddine, Wissam Mansour, Sandy El Bitar, Marco Campitelli, Neville Mobarakai

“…A 52-year-old male, with diabetes mellitus and alcoholic liver disease, presented to the Emergency Room for right flank pain of 3 days’ duration, associated with dysuria. …”
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Effectively Screening for Coronary Artery Disease in Patients Undergoing Orthotopic Liver Transplant Evaluation by Bryan C. Lee, Feng Li, Adam J. Hanje, Khalid Mumtaz, Konstantinos D. Boudoulas, Scott M. Lilly

“…Coronary artery disease (CAD) is prevalent in patients with end-stage liver disease and associated with poor outcomes when undergoing orthotopic liver transplantation (OLT); however, noninvasive screening for CAD in this population is less sensitive. …”
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The Role of Monocyte/Macrophage and CXCR3 in Differentiation between Recurrent Hepatitis C and Acute Cellular Rejection Postliver Transplantation by Asmaa Ibrahim Gomaa, Nermine Ahmed Ehsan, Ahmed A. Elrefaei, Mervat Mohamed Sultan, Maha Mohamed Elsabaawy

“…Liver transplantation (LT) is the recommended treatment for patients with advanced liver disease and cirrhosis in all guidelines, mostly as a complication of HCV. …”
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Foxp3 Expression in Liver Correlates with the Degree but Not the Cause of Inflammation by Matthaios Speletas, Nikoletta Argentou, Georgios Germanidis, Themistoclis Vasiliadis, Konstantinos Mantzoukis, Kalliopi Patsiaoura, Pavlos Nikolaidis, Vaios Karanikas, Konstantinos Ritis, Anastasios E. Germenis

“…Liver biopsies obtained from 69 individuals (26 chronic HBV hepatitis, 14 chronic HCV hepatitis, 11 nonalcoholic fatty liver disease, 8 autoimmune diseases, 2 methotrexate-related toxicity, and 8 controls) were examined, by qRT-PCR, for the mRNA expression of Foxp3, IL-10, TGF-β1, Fas, FasL, TRAIL, caspase-3, TNF-α, IFN-γ, and IL-1β. …”
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Beneficial Effects of Capybara Oil Supplementation on Steatosis and Liver Apoptosis in Obese Mice by Luciana Lontro Alves, Priscila Gomes Pereira, Bianca Torres Ciambarella, Miguel Porto Campos, Kíssila Rabelo, Ana Lúcia Rosa Nascimento, Raíssa Leal de Carvalho dos Santos Cunha, Cherley Borba Vieira Andrade, Alan Cesar Nunes Moraes, Andressa Bernardi, Fernanda Verdini Guimarães, Jemima Fuentes Ribeiro da Silva, Jorge José de Carvalho

“…It may be associated with several diseases, such as nonalcoholic fatty liver disease (NAFLD). Polyunsaturated fatty acids (PUFA) are lipid mediators that have anti-inflammatory characteristics and can be found in animals and plants, with capybara oil (CO) being a promising source. …”
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Altered mitochondrial unfolded protein response and FGF21 secretion in MASLD progression and the effect of exercise intervention by Xinmeng Yuan, Wen Sun, Ye Xu, Mengqi Xiang, Yaran Gao, Wanyu Feng, Hongjian Xiao, Liumei Zhang, Qiang Tang, Jiao Lu, Yuan Zhang

“…Abstract A high-calorie diet and lack of exercise are the most important risk factors contributing to metabolic dysfunction-associated steatotic liver disease (MASLD) initiation and progression. The precise molecular mechanisms of mitochondrial function alteration during MASLD development remain to be fully elucidated. …”
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The Relationship between Inflammatory Marker Levels and Hepatitis C Virus Severity by Qitian He, Quan He, Xue Qin, Shan Li, Taijie Li, Li Xie, Yan Deng, Yu He, Yongbin Chen, Zhifu Wei

“…We aim to investigate the relationship between RDW and PLR and the severity of hepatitis C virus- (HCV-) related liver disease. Methods. We included fifty-two chronic HCV and 42 HCV-related cirrhosis patients and 84 healthy controls. …”
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Point of Care Perioperative Coagulation Management in Liver Transplantation and Complete Portal Vein Thrombosis by Cristiano Piangatelli, Lucia Faloia, Claudia Cristiani, Ilaria Valentini, Marco Vivarelli

“…We report the successful application of a point-of-care (POC) rotational viscoelastic thromboelastometry-guided (TEM) testing system (ROTEM) which allowed management of coagulation during LT in a 64-year-old cirrhotic patient with a model for end-stage liver disease (MELD) score of 16. Perioperatively, the patient showed complete PVT, hepatomegaly, splenomegaly, recanalization of the umbilical vein, and portosystemic shunt. …”
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Development of novel nucleic acid therapy aimed at directly controlling liver fibrosis by Tomohiro Umezu, Masakatsu Takanashi, Koji Fujita, Akio Ishikawa, Yuichirou Harada, Yoshinari Matsumoto, Masahiko Kuroda, Yoshiki Murakami

“…In a mouse model of chronic liver disease treated with carbon tetrachloride (CCl4), the inhibitory effect on liver fibrosis was evaluated with oral administration of the modified nucleic acid. …”
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Slow Metabolism–Driven Amplification of Hepatic PPARγ Agonism Mediates Benzbromarone‐Induced Obesity‐Specific Liver Injury by Guanting Li, Yourong Hu, Han Zhao, Ziyu Peng, Xin Shang, Jia Zhang, Kunxin Xie, Meiwei Li, Xiaohang Zhou, Qinyao Zhou, Kai Li, Fang Zhou, Heyao Wang, Zhijian Xu, Jiali Liu, Peng Sun

“…Abstract Obesity and nonalcoholic fatty liver disease (NAFLD) are established risk factors for drug‐induced liver injury (DILI). …”
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Safety Profile of Liver FibroScan in Patients with Cardiac Pacemakers or Implantable Cardioverter-Defibrillators by Yin Chan, Stephanie Pranke, Farid Rashidi, Shravan Nosib, Lawrence Worobetz

“…Emerging evidence suggests that nonalcoholic fatty liver disease (NAFLD) is associated with coronary artery diseases and arrhythmias. …”
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Mesenchymal Stem Cell Transplantation for Liver Cell Failure: A New Direction and Option by Yantian Cao, Bangjie Zhang, Rong Lin, Qingzhi Wang, Jie Wang, Fangfang Shen

“…Notably, the decreased value (D value) of Model for End-Stage Liver Disease score (MELD) of acute-on-chronic liver failure (ACLF) group was higher than that of chronic liver failure (CLF) group (14.93 ± 1.24 versus 4.6 ± 5.66, P<0.05). …”
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Toll-Like Receptor Signaling and Liver Fibrosis by Tomonori Aoyama, Yong-Han Paik, Ekihiro Seki

“…Liver fibrosis occurs as a wound-healing scar response following acute and chronic liver inflammation including alcoholic liver disease, non-alcoholic steatohepatitis, hepatitis B and C, and autoimmune hepatitis. …”
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Fermented Lentinus edodes extract containing α-glucan ameliorates concanavalin A-induced autoimmune hepatitis in mice by Xin Hu, Dan Cheng, Yingxia Zhang, Po Li, Xiaoping Wu, Junsheng Fu

“…Autoimmune hepatitis (AIH) is a chronic inflammatory liver disease that threatens human health worldwide. …”
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